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MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Macaca thibetana thibetana ]

Gene ID: 126934050, updated on 24-Mar-2024

Summary

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Gene symbol
MTHFD2
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
See related
EnsemblRapid:ENSMTBG00000005963
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca thibetana thibetana (sub-species: thibetana)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MTHFD2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_02 current ASM2454274v1 (GCF_024542745.1) 13 NC_065590.1 (32834884..32851360, complement)

Chromosome 13 - NC_065590.1Genomic Context describing neighboring genes Neighboring gene INO80 complex subunit B Neighboring gene U6 spliceosomal RNA Neighboring gene keratin, type I cytoskeletal 18-like Neighboring gene solute carrier family 4 member 5 Neighboring gene bolA family member 3 Neighboring gene MOB kinase activator 1A Neighboring gene tet methylcytosine dioxygenase 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_065590.1 Chromosome 13 Reference ASM2454274v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_024542745.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2454274v1

Genomic

  1. NC_065590.1 Reference ASM2454274v1

    Range
    32834884..32851360 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_050754496.1 → XP_050610453.1  bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

    Related
    ENSMTBP00000008367.1, ENSMTBT00000010494.1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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