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IQSEC3 IQ motif and Sec7 domain ArfGEF 3 [ Canis lupus familiaris (dog) ]

Gene ID: 486747, updated on 17-Aug-2024

Summary

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Official Symbol
IQSEC3provided by VGNC
Official Full Name
IQ motif and Sec7 domain ArfGEF 3provided by VGNC
Primary source
VGNC:VGNC:42085
See related
Ensembl:ENSCAFG00845026692
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See IQSEC3 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
16
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (42507444..42618070)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (4424441..4534976, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (3784423..3895047, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (42448683..42559183)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (42418597..42529299)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene DEAD/H-box helicase 11 Neighboring gene uncharacterized LOC111092838 Neighboring gene WASH complex subunit 1 Neighboring gene solute carrier family 6 member 12 Neighboring gene solute carrier family 6 member 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Seven novel cosmid-derived canine microsatellites. Schelling C, et al. Anim Genet, 2000 Feb. PMID 10690376
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
IQ motif and SEC7 domain-containing protein 3; LOW QUALITY PROTEIN: IQ motif and SEC7 domain-containing protein 3
Names
IQ motif and Sec7 domain 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    42507444..42618070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038439357.1 → XP_038295285.1  IQ motif and SEC7 domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PPJ4, A0A8I3PQB2
    Related
    ENSCAFP00845036930.1, ENSCAFT00845047058.1
    Conserved Domains (3) summary
    cd14686
    Location:32 → 63
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    pfam01369
    Location:673 → 861
    Sec7; Sec7 domain
    pfam16453
    Location:881 → 1018
    IQ_SEC7_PH; PH domain

  2. XM_038439359.1 → XP_038295287.1  IQ motif and SEC7 domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PJT9
    Conserved Domains (2) summary
    pfam01369
    Location:476 → 664
    Sec7; Sec7 domain
    pfam16453
    Location:684 → 821
    IQ_SEC7_PH; PH domain

  3. XM_038439360.1 → XP_038295288.1  IQ motif and SEC7 domain-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PJV0
    Conserved Domains (2) summary
    pfam01369
    Location:476 → 664
    Sec7; Sec7 domain
    pfam16453
    Location:684 → 821
    IQ_SEC7_PH; PH domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    42448683..42559183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038514017.1 → XP_038369945.1  LOW QUALITY PROTEIN: IQ motif and SEC7 domain-containing protein 3 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    42418597..42529299
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038641865.1 → XP_038497793.1  IQ motif and SEC7 domain-containing protein 3 isoform X2

  2. XM_038641866.1 → XP_038497794.1  IQ motif and SEC7 domain-containing protein 3 isoform X1

RNA

  1. XR_005413924.1 RNA Sequence

  2. XR_005413925.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    3784423..3895047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038576408.1 → XP_038432336.1  IQ motif and SEC7 domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0TS94

  2. XM_038576411.1 → XP_038432339.1  IQ motif and SEC7 domain-containing protein 3 isoform X5

    UniProtKB/TrEMBL
    A0A8C0PJV0, A0A8C0TVW8
    Conserved Domains (2) summary
    pfam01369
    Location:361 → 549
    Sec7; Sec7 domain
    pfam16453
    Location:569 → 706
    IQ_SEC7_PH; PH domain

  3. XM_038576410.1 → XP_038432338.1  IQ motif and SEC7 domain-containing protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PJV0
    Conserved Domains (2) summary
    pfam01369
    Location:446 → 634
    Sec7; Sec7 domain
    pfam16453
    Location:654 → 791
    IQ_SEC7_PH; PH domain

  4. XM_038576409.1 → XP_038432337.1  IQ motif and SEC7 domain-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PJV0
    Conserved Domains (2) summary
    pfam01369
    Location:476 → 664
    Sec7; Sec7 domain
    pfam16453
    Location:684 → 821
    IQ_SEC7_PH; PH domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    4424441..4534976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_543874.6 → XP_543874.2  IQ motif and SEC7 domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8C0TS94
    Conserved Domains (3) summary
    cd14686
    Location:32 → 63
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    pfam01369
    Location:673 → 861
    Sec7; Sec7 domain
    pfam16453
    Location:881 → 1018
    IQ_SEC7_PH; PH domain

  2. XM_038459657.1 → XP_038315585.1  IQ motif and SEC7 domain-containing protein 3 isoform X7

    UniProtKB/TrEMBL
    A0A8C0PJV0, A0A8C0TVW8
    Conserved Domains (2) summary
    pfam01369
    Location:361 → 549
    Sec7; Sec7 domain
    pfam16453
    Location:569 → 706
    IQ_SEC7_PH; PH domain

  3. XM_014108641.3 → XP_013964116.2  IQ motif and SEC7 domain-containing protein 3 isoform X6

    UniProtKB/TrEMBL
    A0A8C0PJV0
    Conserved Domains (2) summary
    pfam01369
    Location:446 → 634
    Sec7; Sec7 domain
    pfam16453
    Location:654 → 791
    IQ_SEC7_PH; PH domain

  4. XM_038459656.1 → XP_038315584.1  IQ motif and SEC7 domain-containing protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PJV0
    Conserved Domains (2) summary
    pfam01369
    Location:476 → 664
    Sec7; Sec7 domain
    pfam16453
    Location:684 → 821
    IQ_SEC7_PH; PH domain
Nucleotide Protein
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