Ag-DNA Emitter: Metal Nanorod or Supramolecular Complex?

J Phys Chem Lett. 2016 Sep 15;7(18):3560-6. doi: 10.1021/acs.jpclett.6b01672. Epub 2016 Aug 29.

Abstract

Ligand-stabilized luminescent metal clusters, in particular, DNA-based Ag clusters, are now employed in a host of applications such as sensing and bioimaging. Despite their utility, the nature of their excited states as well as detailed structures of the luminescent metal-ligand complexes remain poorly understood. We apply a new joint experimental and theoretical approach based on QM/MM-MD simulations of the fluorescence excitation spectra for three Ag clusters synthesized on a 12-mer DNA. Contrary to a previously proposed "rod-like" model, our results show that (1) three to four Ag atoms suffice to form a partially oxidized nanocluster emitting in visible range; (2) charge transfer from Ag cluster to DNA contributes to the excited states of the complexes; and (3) excitation spectra of the clusters are strongly affected by the bonding of Ag atoms to DNA bases. The presented approach can also provide a practical way to determine the structure and properties of other luminescent metal clusters.

Publication types

  • Letter

MeSH terms

  • Coordination Complexes / chemistry*
  • DNA / chemistry*
  • Models, Molecular
  • Nanotubes / chemistry*
  • Silver / chemistry*

Substances

  • Coordination Complexes
  • Silver
  • DNA