TSG-6: a multifunctional protein associated with inflammation (Q34190264)

31 July 2017

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title

TSG-6: a multifunctional protein associated with inflammation (English)

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31 July 2017

0 references

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23 December 2023

1

Caroline M. Milner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692188

reference URL

23 December 2023

2

Anthony J. Day

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12692188

reference URL

23 December 2023

language of work or name

English

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publication date

1 May 2003

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31 July 2017

15 May 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12692188

reference URL

23 December 2023

published in

Journal of Cell Science

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31 July 2017

volume

116

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31 July 2017

issue

Pt 10

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31 July 2017

page(s)

1863-1873

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Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis

31 July 2017

cites work

1

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Up-regulation and differential expression of the hyaluronan-binding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis

23 December 2023

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The source of the inter-alpha trypsin inhibitor in pathologic hyaluronateprotein

23 December 2023

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The CUB domain. A widespread module in developmentally regulated proteins

23 December 2023

4

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Stimulation of the hyaluronic acid levels of human synovial fibroblasts by recombinant human tumor necrosis factor alpha, tumor necrosis factor beta (lymphotoxin), interleukin-1 alpha, and interleukin-1 beta

23 December 2023

5

1 reference

TSG-6 is concentrated in the extracellular matrix of mouse cumulus oocyte complexes through hyaluronan and inter-alpha-inhibitor binding

23 December 2023

8

1 reference

Hyaluronic acid synthesis and gap junction endocytosis are necessary for normal expansion of the cumulus mass

23 December 2023

9

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Functional significance of cumulus expansion in the mouse: roles for the preovulatory synthesis of hyaluronic acid within the cumulus mass

23 December 2023

11

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Covalent linkage between proteins of the inter-alpha-inhibitor family and hyaluronic acid is mediated by a factor produced by granulosa cells

23 December 2023

13

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cDNA array analysis of altered gene expression in human endothelial cells in response to Chlamydia pneumoniae infection

23 December 2023

14

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Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta

23 December 2023

15

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Hyaluronan-binding proteins: tying up the giant

23 December 2023

16

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Organization of the inter-alpha-inhibitor heavy chains on the chondroitin sulfate originating from Ser(10) of bikunin: posttranslational modification of IalphaI-derived bikunin

23 December 2023

19

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FSH stimulates hyaluronic acid synthesis by oocyte–cumulus cell complexes from mouse preovulatory follicles

23 December 2023

20

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Transcriptional Profile of Mechanically Induced Genes in Human Vascular Smooth Muscle Cells

23 December 2023

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A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase.

23 December 2023

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Induction of the hyaluronic acid-binding protein, tumor necrosis factor-stimulated gene-6, in cervical smooth muscle cells by tumor necrosis factor-alpha and prostaglandin E(2).

23 December 2023

25

1 reference

The link module from human TSG-6 inhibits neutrophil migration in a hyaluronan- and inter-alpha -inhibitor-independent manner.

23 December 2023

28

1 reference

Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis

23 December 2023

29

1 reference

Interleukin 1 Enhances Synovial Cell Hyaluronate Synthesis

23 December 2023

30

1 reference

Inter-alpha-inhibitor binding to hyaluronan in the cumulus extracellular matrix is required for optimal ovulation and development of mouse oocytes

23 December 2023

32

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The CUB domains of procollagen C-proteinase enhancer control collagen assembly solely by their effect on procollagen C-proteinase/bone morphogenetic protein-1

23 December 2023

34

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Expression of inter-alpha-trypsin inhibitor and tumor necrosis factor-stimulated gene 6 in renal proximal tubular epithelial cells.

23 December 2023

35

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Role of tumour necrosis factor stimulated gene 6 (TSG-6) in the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human follicular fluid

23 December 2023

36

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Localization and characterization of the hyaluronan-binding site on the link module from human TSG-6.

23 December 2023

37

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Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor

23 December 2023

38

1 reference

NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1

23 December 2023

40

1 reference

Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration

23 December 2023

41

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Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics

23 December 2023

42

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Mechanical strain induces specific changes in the synthesis and organization of proteoglycans by vascular smooth muscle cells

23 December 2023

43

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Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts

23 December 2023

44

1 reference

A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44

23 December 2023

45

1 reference

Mapping the hyaluronan-binding site on the link module from human tumor necrosis factor-stimulated gene-6 by site-directed mutagenesis

23 December 2023

48

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Microarray analysis of lipopolysaccharide-treated human neutrophils

23 December 2023

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Complexity of IL-1 beta induced gene expression pattern in human articular chondrocytes

23 December 2023

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Isolation and characterization of lymphocyte-like cells from a lamprey

23 December 2023

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Oxidized low density lipoprotein exposure alters the transcriptional response of macrophages to inflammatory stimulus

23 December 2023

53

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Amelioration of collagen-induced arthritis in DBA/1J mice by recombinant TSG-6, a tumor necrosis factor/interleukin-1-inducible protein

23 December 2023

54

1 reference

Reduced susceptibility to collagen-induced arthritis in DBA/1J mice expressing the TSG-6 transgene

23 December 2023

55

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Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesion

23 December 2023

56

1 reference

Two distinct populations of tumor necrosis factor-stimulated gene-6 protein in the extracellular matrix of expanded mouse cumulus cell-oocyte complexes

23 December 2023

57

1 reference

Mechanisms for pro matrix metalloproteinase activation.

23 December 2023

58

1 reference

A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression

23 December 2023

59

1 reference

Decreased expression of tumor necrosis factor-alpha-stimulated gene 6 in cumulus cells of the cyclooxygenase-2 and EP2 null mice

23 December 2023

61

1 reference

Overlapping sites on the Link module of human TSG-6 mediate binding to hyaluronan and chrondroitin-4-sulphate

23 December 2023

62

1 reference

TSG-6 interacts with hyaluronan and aggrecan in a pH-dependent manner via a common functional element: implications for its regulation in inflamed cartilage

23 December 2023

63

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A crucial role for CD44 in inflammation

23 December 2023

66

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Ovulation: new dimensions and new regulators of the inflammatory-like response

23 December 2023

67

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The crystal structures of two spermadhesins reveal the CUB domain fold

23 December 2023

69

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The inter-alpha-inhibitor family: from structure to regulation

23 December 2023

70

1 reference

Localization and synthesis of hyaluronic acid in the cumulus cells and mural granulosa cells of the preovulatory follicle

23 December 2023

72

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Impaired fertility in female mice lacking urinary trypsin inhibitor

23 December 2023

74

1 reference

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis

23 December 2023

75

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Differential gene expression in p53-mediated G(1) arrest of human fibroblasts after gamma-irradiation or N-phosphoacetyl-L-aspartate treatment

23 December 2023

76

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Serine proteases of the complement system

23 December 2023

77

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Hyaluronan and homeostasis: a balancing act.

23 December 2023

79

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Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor

23 December 2023

80

1 reference

23 December 2023

Hyaluronan synthases

83

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TSG-6: an IL-1/TNF-inducible protein with anti-inflammatory activity

23 December 2023

84

1 reference

TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor

23 December 2023

87

1 reference

Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells

23 December 2023

89

1 reference

Growth factor and cytokine-regulated hyaluronan-binding protein TSG-6 is localized to the injury-induced rat neointima and confers enhanced growth in vascular smooth muscle cells

23 December 2023

90

1 reference

Expression of tumor necrosis factor-stimulated gene-6 in the rat ovary in response to an ovulatory dose of gonadotropin

23 December 2023

92

1 reference

Evidence for the Covalent Binding of SHAP, Heavy Chains of Inter-α-Trypsin Inhibitor, to Hyaluronan

23 December 2023

93

1 reference

Defect in SHAP-hyaluronan complex causes severe female infertility. A study by inactivation of the bikunin gene in mice

23 December 2023

94

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23 December 2023

Identifiers

DOI

10.1242/JCS.00407

1 reference

31 July 2017

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