Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization (Q35643021)

9 August 2017

title

Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization (English)

1 reference

9 August 2017

3

Hanqing Liu

1 reference

9 August 2017

Ursula D Ramirez

1

1 reference

9 August 2017

Anna S Nikonova

2

1 reference

9 August 2017

Anna Pecherskaya

4

1 reference

9 August 2017

Sarah H Lawrence

5

1 reference

9 August 2017

Ilya G Serebriiskii

6

1 reference

9 August 2017

Yan Zhou

7

1 reference

9 August 2017

Matthew K Robinson

8

1 reference

9 August 2017

Margret B Einarson

9

1 reference

9 August 2017

Erica A Golemis

10

1 reference

9 August 2017

Eileen K Jaffe

11

1 reference

9 August 2017

language of work or name

English

0 references

publication date

28 May 2015

1 reference

9 August 2017

1 reference

9 August 2017

volume

15

1 reference

9 August 2017

page(s)

436

1 reference

Monensin inhibits epidermal growth factor receptor trafficking and activation: synergistic cytotoxicity in combination with EGFR inhibitors

9 August 2017

cites work

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Allosteric modulation of protein oligomerization: an emerging approach to drug design

12 July 2018

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Recruitment of the adaptor protein Grb2 to EGFR tetramers

12 July 2018

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The EGFR family: not so prototypical receptor tyrosine kinases

12 July 2018

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Structure-function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface.

12 July 2018

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Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle

12 July 2018

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Temporal regulation of EGF signalling networks by the scaffold protein Shc1

12 July 2018

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Exploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach

12 July 2018

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12 July 2018

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Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.

12 July 2018

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EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

12 July 2018

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Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling

12 July 2018

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Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy

12 July 2018

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Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer

12 July 2018

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Allostery and the dynamic oligomerization of porphobilinogen synthase

12 July 2018

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Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer

12 July 2018

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Anti-tumor and cell cycle responses in KB cells treated with a chimeric anti-EGFR monoclonal antibody in combination with cisplatin.

12 July 2018

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Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry

12 July 2018

1 reference

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Feedback regulation of EGFR signalling: decision making by early and delayed loops.

12 July 2018

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Synthetic lethal screen of an EGFR-centered network to improve targeted therapies.

12 July 2018

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Structural Basis for Negative Cooperativity in Growth Factor Binding to an EGF Receptor

12 July 2018

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Epidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation

12 July 2018

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Allosteric inhibition of human porphobilinogen synthase

12 July 2018

1 reference

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Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers

12 July 2018

1 reference

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Shape shifting leads to small-molecule allosteric drug discovery

12 July 2018

1 reference

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Unligated epidermal growth factor receptor forms higher order oligomers within microclusters on A431 cells that are sensitive to tyrosine kinase inhibitor binding.

12 July 2018

1 reference

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Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

12 July 2018

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Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation

12 July 2018

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Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis

12 July 2018

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Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3.

12 July 2018

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

12 July 2018

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Lateral propagation of EGF signaling after local stimulation is dependent on receptor density.

12 July 2018

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The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

12 July 2018

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Heregulin reverses the oligomerization of HER3.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451962

Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: oligomerization of kinase domains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451962

Structural alterations of the epidermal growth factor receptor gene in human gliomas

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451962

Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451962

Ectodomain orientation, conformational plasticity and oligomerization of ErbB1 receptors investigated by molecular dynamics.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451962

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451962

Mechanisms of tumor resistance to EGFR-targeted therapies

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26016476

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26016476

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12885-015-1415-6

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

1 reference