Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803 (Q35729861)

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scientific article published on 6 December 2011

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English	Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803	scientific article published on 6 December 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803 (English)

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PubMed publication ID

9 August 2017

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Donna Spiegelman

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Donna Spiegelman

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Jeffrey A Meyerhardt

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Jeffrey A Meyerhardt

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Charles S. Fuchs

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Charles S Fuchs

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Leonard B. Saltz

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Leonard B Saltz

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Nadine Jackson McCleary

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Nadine J McCleary

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Shuji Ogino

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Kimmie Ng

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Donna Hollis

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Paul Schaefer

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Renaud Whittom

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Alexander Hantel

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Alexander Hantel

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Monica Bertagnolli

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Monica M Bertagnolli

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Kaori Shima

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Robert J Mayer

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Al B Benson

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Richard M Goldberg

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6 December 2011

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Clinical Cancer Research

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9 August 2017

890-900

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Europe PubMed Central

PubMed publication ID

9 August 2017

Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum

1 reference

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12 July 2018

Epigenetics and colorectal cancer

1 reference

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Cancer immunology--analysis of host and tumor factors for personalized medicine

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DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

1 reference

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12 July 2018

CpG island methylation in colorectal cancer: past, present and future

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Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).

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12 July 2018

Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer

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Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

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Cigarette smoking and colorectal cancer risk by molecularly defined subtypes

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BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients' outcome

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Oncogenic mutations as predictive factors in colorectal cancer

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Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

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12 July 2018

Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery

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12 July 2018

Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study

1 reference

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12 July 2018

Smoking, gender, and ethnicity predict somatic BRAF mutations in colorectal cancer

1 reference

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12 July 2018

The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status

1 reference

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12 July 2018

Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer

1 reference

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12 July 2018

KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271172

12 July 2018

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer

1 reference

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12 July 2018

Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271172

12 July 2018

Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample

1 reference

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12 July 2018

Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines

1 reference

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12 July 2018

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

1 reference

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Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.

1 reference

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Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.

1 reference

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12 July 2018

Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells

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Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma

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Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer

1 reference

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LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

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CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations

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Molecular determinants of irinotecan efficacy.

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

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Value of mismatch repair, KRAS, and BRAF mutations in predicting recurrence and benefits from chemotherapy in colorectal cancer.

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Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers.

1 reference

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Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis.

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25 September 2018

KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial

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Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases

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Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent oncogenic changes influence survival differences between colon and rectal adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22147942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-11-2246

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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