eptifibatide (Q2295855)

Eptifibatide (English)

18 November 2016

chemical formula

C₃₅H₄₉N₁₁O₉S₂

1 reference

Eptifibatide (English)

18 November 2016

canonical SMILES

C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N

1 reference

Eptifibatide (English)

18 November 2016

isomeric SMILES

C1C[C@H]2C(=O)N[C@@H](CSSCCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N

1 reference

Eptifibatide (English)

parenteral route of administration

18 November 2016

defined daily dose

0.2 gram

route of administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=B01AC16

active ingredient in

Eptifibatide Accord

1 reference

European Medicines Agency product number

EMEA/H/C/004104

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/004104/human_med_001946.jsp

22 March 2017

1 reference

14 February 2018

World Health Organisation international non-proprietary name

eptifibatide (English)

1 reference

Eptifibatide (English)

medical condition treated

19 January 2016

myocardial infarction

1 reference

13 December 2016

coronary artery disease

1 reference

13 December 2016

1 reference

Drug Indications Extracted from FAERS

13 December 2016

1 reference

cerebral artery occlusion

2 October 2018

1 reference

Drug Indications Extracted from FAERS

2 October 2018

7 June 1999

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/NA8320J834

http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020718s034lbl.pdf

significant drug interaction

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

aceclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

vortioxetine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibrutinib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

paroxetine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sertraline

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fluvoxamine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fluoxetine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(S)-duloxetine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

venlafaxine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-citalopram

1 reference

A reference set of clinically relevant adverse drug-drug interactions

anagrelide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

enoxaparin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

dalteparin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tinzaparin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rac-warfarin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fondaparinux

1 reference

A reference set of clinically relevant adverse drug-drug interactions

heparin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

phenindione

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rivaroxaban

1 reference

A reference set of clinically relevant adverse drug-drug interactions

apixaban

1 reference

A reference set of clinically relevant adverse drug-drug interactions

alteplase

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

integrin subunit alpha 2b

subject has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1174

Integrin subunit beta 3

subject has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1174

pregnancy category

US pregnancy category B

1 reference

imported from Wikimedia project

1 reference

Eptifibatide (English)

DrugBank

platelet aggregation inhibitors

17 November 2015

1 reference

Medical Subject Headings

MeSH descriptor ID

C086648

InChI=1S/C35H49N11O9S2/c36-30(51)25-18-57-56-13-10-27(47)42-22(8-3-4-11-39-35(37)38)31(52)41-17-28(48)43-23(15-29(49)50)32(53)44-24(14-19-16-40-21-7-2-1-6-20(19)21)34(55)46-12-5-9-26(46)33(54)45-25/h1-2,6-7,16,22-26,40H,3-5,8-15,17-18H2,(H2,36,51)(H,41,52)(H,42,47)(H,43,48)(H,44,53)(H,45,54)(H,49,50)(H4,37,38,39)/t22-,23-,24-,25-,26-/m0/s1

15 March 2018

Identifiers

InChI

1 reference

Eptifibatide (English)

18 November 2016

2 references

Eptifibatide (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

188627-80-7

1 reference

eptifibatide (English)

18 November 2016

1 reference

Eptifibatide (English)

18 November 2016

2 references

Eptifibatide (English)

18 November 2016

Reaxys registry number

9608167

1 reference

eptifibatide (English)

3 October 2016

ChEBI ID

291902

mapping relation type

2 references

EPTIFIBATIDE (English)

18 November 2016

International Chemical Identifier

InChI

InChI=1S/C35H49N11O9S2/c36-30(51)25-18-57-56-13-10-27(47)42-22(8-3-4-11-39-35(37)38)31(52)41-17-28(48)43-23(15-29(49)50)32(53)44-24(14-19-16-40-21-7-2-1-6-20(19)21)34(55)46-12-5-9-26(46)33(54)45-25/h1-2,6-7,16,22-26,40H,3-5,8-15,17-18H2,(H2,36,51)(H,41,52)(H,42,47)(H,43,48)(H,44,53)(H,45,54)(H,49,50)(H4,37,38,39)/t22-,23-,24-,25-,26-/m0/s1

1 reference

EPTIFIBATIDE (English)

18 November 2016

2 references

inferred from InChIKey

Hazardous Substances Data Bank

1 reference

1 reference

28 October 2019

Eptifibatide (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

DTXCID5026673

0 references

EC number

641-366-7

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.169.160

27 December 2018

ECHA Substance Infocard ID

Eptifibatide (English)

quotation

CAS no.: 188627-80-7 (English)

100.169.160

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.169.160

27 December 2018

Eptifibatide (English)

quotation

CAS no.: 188627-80-7 (English)

1 reference

Guide to Pharmacology Ligand ID

Eptifibatide (English)

publication date

17 November 2015

6585

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6585

eptifibatide (English)

18 November 2016

Eptifibatide

0 references

0 references

1 reference

eptifibatide (English)

18 November 2016

0 references

2 references

eptifibatide (English)

18 November 2016

PatientsLikeMe treatment ID

0 references

1 reference

eptifibatide (English)

18 November 2016

0 references

1 reference

1 reference

Immune Epitope Database and Analysis Resource

eptifibatide (English)

3 October 2016

1 reference

1 March 2022

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C0253563

1 reference

eptifibatide (English)

inferred by common MeSH mappings on source and on Wikidata

18 November 2016

C0950902

1 reference

based on heuristic

UMLS 2023