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Fast Green FCF: Difference between revisions

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[[Category:Biochemistry detection methods]]
[[Category:Triarylmethane dyes]]
[[Category:Triarylmethane dyes]]
[[Category:Staining dyes]]
[[Category:Staining dyes]]

Revision as of 11:23, 9 March 2021

Fast Green FCF
Names
IUPAC name
ethyl-[4-[[4-[ethyl-[(3-sulfophenyl)methyl]amino]phenyl]-(4-hydroxy-2-sulfophenyl)methylidene]-1-cyclohexa-2,5-dienylidene]-[(3-sulfophenyl)methyl]azanium
Other names
Food green 3,
FD&C Green No. 3,
Green 1724,
Solid Green FCF, and
C.I. 42053
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.017.356 Edit this at Wikidata
E number E143 (colours)
KEGG
UNII
  • InChI=1S/C37H36N2O10S3.2Na/c1-3-38(24-26-7-5-9-33(21-26)50(41,42)43)30-15-11-28(12-16-30)37(35-20-19-32(40)23-36(35)52(47,48)49)29-13-17-31(18-14-29)39(4-2)25-27-8-6-10-34(22-27)51(44,45)46;;/h5-23H,3-4,24-25H2,1-2H3,(H3,41,42,43,44,45,46,47,48,49);;/q;2*+1/p-2 checkY
    Key: RZSYLLSAWYUBPE-UHFFFAOYSA-L checkY
  • InChI=1/C37H36N2O10S3.2Na/c1-3-38(24-26-7-5-9-33(21-26)50(41,42)43)30-15-11-28(12-16-30)37(35-20-19-32(40)23-36(35)52(47,48)49)29-13-17-31(18-14-29)39(4-2)25-27-8-6-10-34(22-27)51(44,45)46;;/h5-23H,3-4,24-25H2,1-2H3,(H3,41,42,43,44,45,46,47,48,49);;/q;2*+1/p-2
    Key: RZSYLLSAWYUBPE-NUQVWONBAL
  • CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC=C(C=C2)C(=C3C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3)C5=C(C=C(C=C5)O)S(=O)(=O)[O-].[Na+].[Na+]
Properties
C37H34N2O10S3+
Molar mass 765.89 g/mol
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
2
1
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Fast Green FCF, also called Food green 3, FD&C Green No. 3, Green 1724, Solid Green FCF, and C.I. 42053, is a turquoise triarylmethane food dye. Its E number is E143.

Fast Green FCF is recommended as a replacement of Light Green SF yellowish in Masson's trichrome, as its color is more brilliant and less likely to fade. It is used as a quantitative stain for histones at alkaline pH after acid extraction of DNA. It is also used as a protein stain in electrophoresis. Its absorption maximum is at 625 nm.

Fast Green FCF is poorly absorbed by the intestines.[1] Its use as a food dye is prohibited in the European Union and some other countries. It can be used for tinned green peas and other vegetables, jellies, sauces, fish, desserts, and dry bakery mixes at level of up to 100 mg/kg.[2] In the United States, Fast Green FCF is the least used of the seven main FDA approved dyes.

Toxicology

This substance has been found to have tumorigenic effects in experimental animals, as well as mutagenic effects in both experimental animals and humans. It furthermore risks irritation of eyes, skin, digestive tract, and respiratory tract in its undiluted form.[3]

Notes

  1. ^ "Fast Green FCF". IPCS INchem. Archived from the original on 2014-07-01. Retrieved 2007-10-18.
  2. ^ "Fast Green FCF, INS: 143". Food and Agriculture Organisation of the United Nations. Retrieved 2007-10-18.
  3. ^ http://fscimage.fishersci.com/msds/60270.htm
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