Early Release Articles

Last updated November 7, 2024

Early Release Articles are published online ahead of the issue in which they appear. The online first release date serves as the official date of publication. Upon release of the article's scheduled issue, the Early Release article (which may not be the final version) will move from this index to the issue's full Table of Contents in its final edited form.

November 7, 2024

    Corrigendum: Preclinical Modeling of Pathway-Targeted Therapy of Human Lung Cancer in the Mouse
    • Aria Vaishnavi,
    • Conan G. Kinsey,
    • and Martin McMahon
    Cold Spring Harb Perspect Med a041815doi:10.1101/cshperspect.a041815

November 5, 2024

    Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities
    • Navdeep S. Chandel,
    • Karen H. Vousden,
    • and Ralph J. DeBerardinis
    Cold Spring Harb Perspect Med a041814doi:10.1101/cshperspect.a041814
    Dopamine Cell-Based Replacement Therapies
    • Saeed Kayhanian and
    • Roger A. Barker
    Cold Spring Harb Perspect Med a041611doi:10.1101/cshperspect.a041611
    Epitope Hierarchy in Type 1 Diabetes Pathogenesis
    • Thomas Delong and
    • Maki Nakayama
    Cold Spring Harb Perspect Med a041594doi:10.1101/cshperspect.a041594

September 16, 2024

    Cancer Metabolism: Aspirations for the Coming Decade
    • Ralph J. DeBerardinis,
    • Karen H. Vousden,
    • and Navdeep S. Chandel
    Cold Spring Harb Perspect Med a041555doi:10.1101/cshperspect.a041555
    Rebalancing the Immune System to Treat Type 1 Diabetes
    • Yannick D. Muller,
    • Patrick Ho,
    • Jeffrey A. Bluestone,
    • and Qizhi Tang
    Cold Spring Harb Perspect Med a041599doi:10.1101/cshperspect.a041599
    Autoantigen-Specific Immunotherapies for the Prevention and Treatment of Type 1 Diabetes
    • Mark Peakman and
    • Pere Santamaria
    Cold Spring Harb Perspect Med a041598doi:10.1101/cshperspect.a041598
    Technologies for Decoding Cancer Metabolism with Spatial Resolution
    • Walter W. Chen,
    • Michael E. Pacold,
    • David M. Sabatini,
    • and Naama Kanarek
    Cold Spring Harb Perspect Med a041553doi:10.1101/cshperspect.a041553
    Understanding the Warburg Effect in Cancer
    • Zhaoqi Li,
    • Muhammad Bin Munim,
    • Daniel A. Sharygin,
    • Brooke J. Bevis,
    • and Matthew G. Vander Heiden
    Cold Spring Harb Perspect Med a041532doi:10.1101/cshperspect.a041532
    Ovarian Clear Cell Carcinoma: An Endometriosis-Associated Cancer with Therapeutic Challenges
    • Ruby Yun-Ju Huang and
    • Jimmy Jin-Che Lin
    Cold Spring Harb Perspect Med a041315doi:10.1101/cshperspect.a041315
    The Teplizumab Saga: The Challenge of Not Getting Lost in Clinical Translation
    • Lucienne Chatenoud,
    • Kevan C. Herold,
    • Jean-François Bach,
    • and Jeffrey A. Bluestone
    Cold Spring Harb Perspect Med a041600doi:10.1101/cshperspect.a041600

August 12, 2024

    The Human Pancreas in Type 1 Diabetes: Lessons Learned from the Network of Pancreatic Organ Donors with Diabetes
    • Irina Kusmartseva,
    • Amanda Posgai,
    • Mingder Yang,
    • Richard Oram,
    • Mark Atkinson,
    • Alberto Pugliese,
    • and Carmella Evans-Molina
    Cold Spring Harb Perspect Med a041588doi:10.1101/cshperspect.a041588
    Genetics and Epigenetics of Type 1 Diabetes Self-Reactive T Cells
    • Tae Gun Kang and
    • Benjamin Youngblood
    Cold Spring Harb Perspect Med a041586doi:10.1101/cshperspect.a041586
    The Role of B Lymphocytes in Type 1 Diabetes
    • Mia J. Smith,
    • Joanne Boldison,
    • and F. Susan Wong
    Cold Spring Harb Perspect Med a041593doi:10.1101/cshperspect.a041593
    The Pathogenesis of Type 1 Diabetes
    • Kevan C. Herold and
    • Jeffrey P. Krischer
    Cold Spring Harb Perspect Med a041623doi:10.1101/cshperspect.a041623
    Genetics of Parkinson's Disease: From Causes to Treatment
    • Ana Westenberger,
    • Norbert Brüggemann,
    • and Christine Klein
    Cold Spring Harb Perspect Med a041774doi:10.1101/cshperspect.a041774

July 29, 2024

    Innate Immunity in Type 1 Diabetes
    • Léo Bertrand,
    • Alexander V. Chervonsky,
    • and Agnès Lehuen
    Cold Spring Harb Perspect Med a041595doi:10.1101/cshperspect.a041595
    Advances in Islet Transplantation and the Future of Stem Cell–Derived Islets to Treat Diabetes
    • Timothy J. Kieffer,
    • Corinne A. Hoesli,
    • and A.M. James Shapiro
    Cold Spring Harb Perspect Med a041624doi:10.1101/cshperspect.a041624
    Angiogenesis: Biology and Pathology, Second Edition
    • Diane R. Bielenberg and
    • Patricia A. D'Amore
    Cold Spring Harb Perspect Med a041779doi:10.1101/cshperspect.a041779

July 25, 2024

    Corrigendum: Modeling Parkinson's Disease in Primates
    • Erwan Bezard,
    • Margaux Teil,
    • Marie-Laure Arotcarena,
    • Gregory Porras,
    • Qin Li,
    • and Benjamin Dehay
    Cold Spring Harb Perspect Med a041802doi:10.1101/cshperspect.a041802

July 22, 2024

    Cross Talk between β Cells and Immune Cells: What We Know, What We Think We Know, and What We Should Learn
    • Fatoumata Samassa,
    • Capucine Holtzmann,
    • and Roberto Mallone
    Cold Spring Harb Perspect Med a041604doi:10.1101/cshperspect.a041604
    Inflammatory β-Cell Stress and Immune Surveillance in Type 1 Diabetes
    • Anil Bhushan and
    • Peter J. Thompson
    Cold Spring Harb Perspect Med a041605doi:10.1101/cshperspect.a041605
    Checkpoint Inhibitor-Induced Autoimmune Diabetes: An Autoinflammatory Disease
    • Zoe Quandt,
    • Ana Perdigoto,
    • Mark S. Anderson,
    • and Kevan C. Herold
    Cold Spring Harb Perspect Med a041603doi:10.1101/cshperspect.a041603

July 15, 2024

    Targeting Hyperactive Ras Signaling in Pediatric Cancer
    • Anya Levinson,
    • Kevin Shannon,
    • and Benjamin J. Huang
    Cold Spring Harb Perspect Med a041572doi:10.1101/cshperspect.a041572
    Imaging Tumor Metabolism
    • Thomas Ruan and
    • Kayvan R. Keshari
    Cold Spring Harb Perspect Med a041551doi:10.1101/cshperspect.a041551
    Metabolic Reprogramming in Human Cancer Patients and Patient-Derived Models
    • Teresa W.-M. Fan,
    • Richard M. Higashi,
    • and Andrew N. Lane
    Cold Spring Harb Perspect Med a041552doi:10.1101/cshperspect.a041552
    Principles in the Development of Contemporary Treatment of Childhood Malignancies: The First 75 Years
    • Katie A. Greenzang and
    • Stephen E. Sallan
    Cold Spring Harb Perspect Med a041634doi:10.1101/cshperspect.a041634
    Immunotherapies for Childhood Cancer
    • Jeong A. Park and
    • Nai-Kong V. Cheung
    Cold Spring Harb Perspect Med a041574doi:10.1101/cshperspect.a041574
    Modeling Parkinson's Disease in Primates
    • Erwan Bezard,
    • Margaux Teil,
    • Marie-Laure Arotcarena,
    • Gregory Porras,
    • Qin Li,
    • and Benjamin Dehay
    Cold Spring Harb Perspect Med a041612doi:10.1101/cshperspect.a041612

July 1, 2024

    Interactions of Fatty Acid and Cholesterol Metabolism with Cellular Stress Response Pathways in Cancer
    • Alina M. Winkelkotte,
    • Kamal Al-Shami,
    • Adriano B. Chaves-Filho,
    • Felix C.E. Vogel,
    • and Almut Schulze
    Cold Spring Harb Perspect Med a041548doi:10.1101/cshperspect.a041548
    Toxin-Induced Animal Models of Parkinson's Disease
    • Kim Tieu,
    • Said S. Salehe,
    • and Harry J. Brown
    Cold Spring Harb Perspect Med a041643doi:10.1101/cshperspect.a041643
    The Chicken or the Egg Dilemma: Understanding the Interplay between the Immune System and the β Cell in Type 1 Diabetes
    • Maria Skjøtt Hansen,
    • Pravil Pokharel,
    • Jon Piganelli,
    • and Lori Sussel
    Cold Spring Harb Perspect Med a041591doi:10.1101/cshperspect.a041591

June 10, 2024

    Metabolic Signaling in Cancer
    • Laura V. Pinheiro,
    • Pedro Costa-Pinheiro,
    • and Kathryn E. Wellen
    Cold Spring Harb Perspect Med a041544doi:10.1101/cshperspect.a041544
    Historical Perspectives of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies
    • Christopher G. Goetz
    Cold Spring Harb Perspect Med a041642doi:10.1101/cshperspect.a041642
    Lessons Learned from Cancer Metabolism for Physiology and Disease
    • Sydney L. Campbell and
    • Heather R. Christofk
    Cold Spring Harb Perspect Med a041554doi:10.1101/cshperspect.a041554

May 28, 2024

May 21, 2024

    Advances in Studying Cancer Immunology in Mice
    • Marcus Bosenberg
    Cold Spring Harb Perspect Med a041682doi:10.1101/cshperspect.a041682
    Developmental Heterogeneity of Rhabdomyosarcoma
    • Bradley T. Stevens and
    • Mark E. Hatley
    Cold Spring Harb Perspect Med a041583doi:10.1101/cshperspect.a041583
    The Evolution of Mouse Models of Cancer: Past, Present, and Future
    • Cory Abate-Shen and
    • Katerina Politi
    Cold Spring Harb Perspect Med a041736doi:10.1101/cshperspect.a041736
    The Gut–Brain Axis in Parkinson's Disease
    • Virginia Gao,
    • Carl V. Crawford,
    • and Jacqueline Burré
    Cold Spring Harb Perspect Med a041618doi:10.1101/cshperspect.a041618

May 1, 2024

    Mitochondria and Cancer
    • Timothy C. Kenny and
    • Kıvanç Birsoy
    Cold Spring Harb Perspect Med a041534doi:10.1101/cshperspect.a041534
    Angiogenesis and Microvascular Permeability
    • Ye Zeng and
    • Bingmei M. Fu
    Cold Spring Harb Perspect Med a041163doi:10.1101/cshperspect.a041163
    Vascular Organization: Lessons from Development and Disease
    • Steve Spurgin and
    • Ondine Cleaver
    Cold Spring Harb Perspect Med a041160doi:10.1101/cshperspect.a041160
    Mechanics of Lymphatic Pumping and Lymphatic Function
    • Mohammad S. Razavi,
    • Lance L. Munn,
    • and Timothy P. Padera
    Cold Spring Harb Perspect Med a041171doi:10.1101/cshperspect.a041171

April 15, 2024

    Diet and Cancer Metabolism
    • Jason W. Locasale,
    • Marcus D. Goncalves,
    • Maira Di Tano,
    • and Guillermo Burgos-Barragan
    Cold Spring Harb Perspect Med a041549doi:10.1101/cshperspect.a041549
    Harnessing Antitumor Immunity in Ovarian Cancer
    • Katherine C. Kurnit and
    • Kunle Odunsi
    Cold Spring Harb Perspect Med a041336doi:10.1101/cshperspect.a041336

April 2, 2024

    Prostanoids Regulate Angiogenesis and Lymphangiogenesis in Pathological Conditions
    • Masataka Majima,
    • Yasuhiro Matsuda,
    • Shin-Ichi Watanabe,
    • Yasuaki Ohtaki,
    • Kanako Hosono,
    • Yoshiya Ito,
    • and Hideki Amano
    Cold Spring Harb Perspect Med a041182doi:10.1101/cshperspect.a041182
    Retinal Disorders
    • José-Alain Sahel,
    • Eyal Banin,
    • Jean Bennett,
    • Jacque L. Duncan,
    • and Botond Roska
    Cold Spring Harb Perspect Med a041728doi:10.1101/cshperspect.a041728

October 17, 2023

    Neurotrophic Factors in the Treatment of Inherited Retinal Diseases
    • Laure Blouin,
    • José-Alain Sahel,
    • and Daniel C. Chung
    Cold Spring Harb Perspect Med a041665doi:10.1101/cshperspect.a041665

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