http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_05555cdd4aa3ec47746878b037248531
Outgoing Links
| Predicate | Object |
|---|---|
| family-name | Wong |
| name | Kwok-Kin Wong |
| given-name | Kwok-Kin |
| organization-name | 4Lowe Center for Thoracic Oncology and; 5Department of Medical Oncology, Dana-Farber Cancer Institute;; 7Departments of Medicine, Brigham and Women's Hospital and Harvard Medical School; Authors' Affiliations: 1Departments of Medical Oncology and 5Biological Chemistry and Molecular Pharmacology, 18 Center for Cancer Genome Discovery, and 21Ludwig Center, Dana-Farber Cancer Institute, Boston; 4Broad Institute, Cambridge, Massachusetts; 2Max Planck Institute for Neurological Research, Klaus-Joachim-Zülch Laboratories of the Max Planck Society, and University of Köln Medical Faculty; 3Department I of Internal Medicine and Laboratory of Translational Cancer Genomics, Center for Integrated Oncology Köln-Bonn, University of Köln; 9Department I of Internal Medicine, Center for Integrated Oncology Köln-Bonn, University Hospital of Cologne; 15Kliniken der Stadt Köln gGmbH, Cologne; 6Chemical Genomics Center of the Max Planck Society and 19Technical University Dortmund, Dortmund; 13Department of Hematology/Oncology, Jena University Hospital, Jena, Germany; 7Department of Obstetrics and Gynecology, Haukeland University Hospital, and 8Department of Clinical Medicine, University of Bergen, Bergen; 12Divi; Authors' Affiliations: 1Departments of Medical Oncology and 5Biological Chemistry and Molecular Pharmacology, 18 Center for Cancer Genome Discovery, and 21Ludwig Center, Dana-Farber Cancer Institute, Boston; 4Broad Institute, Cambridge, Massachusetts; 2Max Planck Institute for Neurological Research, Klaus-Joachim-Zülch Laboratories of the Max Planck Society, and University of Köln Medical Faculty; 3Department I of Internal Medicine and Laboratory of Translational Cancer Genomics, Center for Integrated Oncology Köln-Bonn, University of Köln; 9Department I of Internal Medicine, Center for Integrated Oncology Köln-Bonn, University Hospital of Cologne; 15Kliniken der Stadt Köln gGmbH, Cologne; 6Chemical Genomics Center of the Max Planck Society and 19Technical University Dortmund, Dortmund; 13Department of Hematology/Oncology, Jena University Hospital, Jena, Germany; 7Department of Obstetrics and Gynecology, Haukeland University Hospital, and 8Department of Clinical Medicine, University of Bergen, Bergen; 12Divi Department of Medical Oncology,; Departments of bMedicine and; Department of cMedicine and Authors' Affiliations: 1Department of Medicine, Harvard Medical School; Departments of 2Medical Oncology and 3Imaging, 4Lowe Center for Thoracic Oncology, 5Department of Pediatrics, Columbia University Medical Center, New York, New York, 6Ludwig Center at Dana-Farber/Harvard Cancer Center, 7Early Drug Development Center, Dana-Farber Cancer Institute; 8Department of Medical Oncology, Massachusetts General Hospital Cancer Center; 9Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; and 10Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, North Carolina; Authors' Affiliations: 1Department of Medicine, Harvard Medical School; Departments of 2Medical Oncology and 3Imaging, 4Lowe Center for Thoracic Oncology, 5Department of Pediatrics, Columbia University Medical Center, New York, New York, 6Ludwig Center at Dana-Farber/Harvard Cancer Center, 7Early Drug Development Center, Dana-Farber Cancer Institute; 8Department of Medical Oncology, Massachusetts General Hospital Cancer Center; 9Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; and 10Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, North Carolina; Authors' Affiliations: 1Department of Medicine, Harvard Medical School; Departments of 2Medical Oncology and 3Imaging, 4Lowe Center for Thoracic Oncology, 5Department of Pediatrics, Columbia University Medical Center, New York, New York, 6Ludwig Center at Dana-Farber/Harvard Cancer Center, 7Early Drug Development Center, Dana-Farber Cancer Institute; 8Department of Medical Oncology, Massachusetts General Hospital Cancer Center; 9Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; and 10Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, North Carolina; Authors' Affiliations: 1Department of Medicine, Harvard Medical School; Departments of 2Medical Oncology and 3Imaging, 4Lowe Center for Thoracic Oncology, 5Department of Pediatrics, Columbia University Medical Center, New York, New York, 6Ludwig Center at Dana-Farber/Harvard Cancer Center, 7Early Drug Development Center, Dana-Farber Cancer Institute; 8Department of Medical Oncology, Massachusetts General Hospital Cancer Center; 9Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; and 10Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, North Carolina Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02215; Division of Hematology and Medical Oncology, Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA. Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA 1Department of Medical Oncology and; 3Ludwig Center at Dana-Farber/Harvard Cancer Center; Departments of; 4Medicine and 1Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 8Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; 9Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts. 13Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York. 7Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York. Authors' Affiliations: 1Merrimack Pharmaceuticals, Inc., Cambridge, Massachusetts; 2Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts; 3Department of Medical Oncology, Dana-Farber Cancer Institute; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Department of Medicine, Harvard Medical School, Boston, Massachusetts; and 6Cell Signaling Technology, Danvers, Massachusetts; Authors' Affiliations: 1Merrimack Pharmaceuticals, Inc., Cambridge, Massachusetts; 2Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts; 3Department of Medical Oncology, Dana-Farber Cancer Institute; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Department of Medicine, Harvard Medical School, Boston, Massachusetts; and 6Cell Signaling Technology, Danvers, Massachusetts; Authors' Affiliations: 1Merrimack Pharmaceuticals, Inc., Cambridge, Massachusetts; 2Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts; 3Department of Medical Oncology, Dana-Farber Cancer Institute; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Department of Medicine, Harvard Medical School, Boston, Massachusetts; and 6Cell Signaling Technology, Danvers, Massachusetts 2Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York. Authors' Affiliations: 1Harvard Radiation Oncology Program; 2Division of Medical Sciences, Harvard University; 3Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School; 4Department of Medical Oncology, 5Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute; 6Department of Pathology, Brigham and Women's Hospital, Boston; 7Chemical Biology Program; 8Howard Hughes Medical Institute, 9The Broad Institute of MIT and Harvard; 10Novartis Institute for Biomedical Research; 11Department of Chemistry and Chemical Biology, 12Harvard University, Cambridge, Massachusetts; and 13Department of Medicine, Baylor College of Medicine, Houston, Texas; Authors' Affiliations: 1Harvard Radiation Oncology Program; 2Division of Medical Sciences, Harvard University; 3Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School; 4Department of Medical Oncology, 5Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute; 6Department of Pathology, Brigham and Women's Hospital, Boston; 7Chemical Biology Program; 8Howard Hughes Medical Institute, 9The Broad Institute of MIT and Harvard; 10Novartis Institute for Biomedical Research; 11Department of Chemistry and Chemical Biology, 12Harvard University, Cambridge, Massachusetts; and 13Department of Medicine, Baylor College of Medicine, Houston, Texas 2Dana-Farber Cancer Institute, The Lowe Center for Thoracic Oncology, Boston, Massachusetts; 1Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.; 7Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York University, New York, New York. 1Division of Hematology and Medical Oncology, Laura and Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, New York. Dana Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Center for Cancer Genome Discovery, 3Department of Medical Oncology, 4Department of Cancer Biology, and 5Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute; 6Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 7Medicine, 8Pathology, and 9Genetics Division, Brigham and Women's Hospital, Boston; 10Broad Institute of Harvard and MIT, Cambridge, Massachusetts; 11Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania; Departments of 12Pediatrics, 13Medicine, and 14Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York; and 15Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Center for Cancer Genome Discovery, 3Department of Medical Oncology, 4Department of Cancer Biology, and 5Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute; 6Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 7Medicine, 8Pathology, and 9Genetics Division, Brigham and Women's Hospital, Boston; 10Broad Institute of Harvard and MIT, Cambridge, Massachusetts; 11Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania; Departments of 12Pediatrics, 13Medicine, and 14Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York; and 15Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Center for Cancer Genome Discovery, 3Department of Medical Oncology, 4Department of Cancer Biology, and 5Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute; 6Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 7Medicine, 8Pathology, and 9Genetics Division, Brigham and Women's Hospital, Boston; 10Broad Institute of Harvard and MIT, Cambridge, Massachusetts; 11Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania; Departments of 12Pediatrics, 13Medicine, and 14Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York; and 15Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Center for Cancer Genome Discovery, 3Department of Medical Oncology, 4Department of Cancer Biology, and 5Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute; 6Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 7Medicine, 8Pathology, and 9Genetics Division, Brigham and Women's Hospital, Boston; 10Broad Institute of Harvard and MIT, Cambridge, Massachusetts; 11Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania; Departments of 12Pediatrics, 13Medicine, and 14Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York; and 15Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois Authors' Affiliations: Departments of 1Medical Oncology and 2Cancer Biology; 3Center for Cancer Genome Discovery, 4Lowe Center for Thoracic Oncology, and 5Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute; Departments of 6Medicine, Brigham and Women's Hospital; Departments of 7Biological Chemistry and Molecular Pharmacology and 8Pathology, Harvard Medical School, Boston, Massachusetts; 9Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea; and 10The Broad Institute of Harvard and MIT, Cambridge, Massachusetts; Authors' Affiliations: Departments of 1Medical Oncology and 2Cancer Biology; 3Center for Cancer Genome Discovery, 4Lowe Center for Thoracic Oncology, and 5Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute; Departments of 6Medicine, Brigham and Women's Hospital; Departments of 7Biological Chemistry and Molecular Pharmacology and 8Pathology, Harvard Medical School, Boston, Massachusetts; 9Samsung Genome Institute, Samsung Medical Center, Seoul, Republic of Korea; and 10The Broad Institute of Harvard and MIT, Cambridge, Massachusetts Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Ludwig Center at Dana-Farber/Harvard Cancer Center, Boston, MA, USA Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Perlmutter Cancer Center, New York University, Langone Medical Center, New York, New York, USA Authors' Affiliations: Departments of 1Cancer Biology and 2Medical Oncology; 3Departments of Medicine and Medical Oncology, Ludwig Center at Dana-Farber–Harvard Cancer Center; 4Lowe Center for Thoracic Oncology; 5Lurie Family Imaging Center, Dana-Farber Cancer Institute; 6Division of Genetics, Howard Hughes Medical Institute; 7Department of Medicine, Brigham and Women's Hospital; 8Department of Radiation Oncology, Massachusetts General Hospital; Departments of 9Biological Chemistry and Molecular Pharmacology and 10Genetics, 11Center for Cell Decision Processes, Department of Systems Biology, Harvard Medical School; 12Harvard Radiation Oncology Program, Boston; 13Whitehead Institute for Biomedical Research; 14Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology; 15Koch Center for Integrative Cancer Research at Massachusetts Institute of Technology, Cambridge, Massachusetts; and 16ActivX Biosciences, Inc., La Jolla, California 6Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; and 3Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York. Authors' Affiliations: 1University of Pittsburgh Cancer Institute, Pittsburgh; 2Penn State Hershey Cancer Institute, Hershey, Pennsylvania; 3Premiere Oncology, Santa Monica; 4City of Hope, Duarte, California; 5Synta Pharmaceuticals Corp., Lexington; 6Massachusetts General Hospital; 7Beth Israel Deaconess Medical Center; 8Dana-Farber Cancer Institute, Boston, Massachusetts; 9Vanderbilt Ingram Cancer Center, Nashville, Tennessee; 10Piedmont Hematology Oncology Associates, Winston-Salem, North Carolina; 11University of Chicago Medical Center; 12Rush University Medical Center, Chicago, Illinois; 13Swedish Cancer Center, Seattle, Washington; 14Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland; 15Nevada Cancer Institute, Las Vegas, Nevada; 16OHSU, Knight Cancer Institute, Portland, Oregon; 17Genesis Cancer Center, Hot Springs, Arkansas; 18Hackensack University Medical Center, Hackensack, New Jersey; and 19Winship Cancer Institute, Emory University, Atlanta, Georgia 1Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York. 7Department of Medical Oncology and Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute Center and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 16Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York. 5Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. 1Laura & Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York. 24Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York. Authors' Affiliations: 1Massachusetts General Hospital Cancer Center, Charlestown; 2Department of Medicine, Harvard Medical School; 3Department of Medical Oncology, Dana-Farber Cancer Institute; and 4Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts; Authors' Affiliations: 1Massachusetts General Hospital Cancer Center, Charlestown; 2Department of Medicine, Harvard Medical School; 3Department of Medical Oncology, Dana-Farber Cancer Institute; and 4Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 9NYU Langone Health, New York, New York. 2Department of Medical Oncology, 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 2Department of Medicine, Harvard Medical School, Boston, Massachusetts.; 3Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 1Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. *Department of Medical Oncology, Dana–Farber Cancer Institute, Boston, MA 02115;; Departments of **Medicine and 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.; 2Department of Medicine, Harvard Medical School, Boston, Massachusetts.; 11Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts. Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. Authors' Affiliations: 1Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of 2Medical Oncology and 3Radiation Oncology; 4Belfer Institute for Applied Cancer Science; 5Ludwig Center at Dana-Farber/Harvard Cancer Center; 6Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; 7Department of Medicine, Brigham and Women's Hospital; 8Department of Medicine, Harvard Medical School, Boston, Massachusetts; 9Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and 10Department of Pediatrics, Columbia University Medical Center, New York, New York; Authors' Affiliations: 1Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of 2Medical Oncology and 3Radiation Oncology; 4Belfer Institute for Applied Cancer Science; 5Ludwig Center at Dana-Farber/Harvard Cancer Center; 6Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; 7Department of Medicine, Brigham and Women's Hospital; 8Department of Medicine, Harvard Medical School, Boston, Massachusetts; 9Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and 10Department of Pediatrics, Columbia University Medical Center, New York, New York; Authors' Affiliations: 1Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of 2Medical Oncology and 3Radiation Oncology; 4Belfer Institute for Applied Cancer Science; 5Ludwig Center at Dana-Farber/Harvard Cancer Center; 6Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; 7Department of Medicine, Brigham and Women's Hospital; 8Department of Medicine, Harvard Medical School, Boston, Massachusetts; 9Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and 10Department of Pediatrics, Columbia University Medical Center, New York, New York; Authors' Affiliations: 1Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of 2Medical Oncology and 3Radiation Oncology; 4Belfer Institute for Applied Cancer Science; 5Ludwig Center at Dana-Farber/Harvard Cancer Center; 6Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; 7Department of Medicine, Brigham and Women's Hospital; 8Department of Medicine, Harvard Medical School, Boston, Massachusetts; 9Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and 10Department of Pediatrics, Columbia University Medical Center, New York, New York; Authors' Affiliations: 1Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of 2Medical Oncology and 3Radiation Oncology; 4Belfer Institute for Applied Cancer Science; 5Ludwig Center at Dana-Farber/Harvard Cancer Center; 6Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; 7Department of Medicine, Brigham and Women's Hospital; 8Department of Medicine, Harvard Medical School, Boston, Massachusetts; 9Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and 10Department of Pediatrics, Columbia University Medical Center, New York, New York Authors' Affiliations: Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain; Authors' Affiliations: Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain; Authors' Affiliations: Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain; Authors' Affiliations: Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain 6Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York. Department of Medical Oncology, Dana–Farber Cancer Institute, Boston, MA 02115;; Ludwig Center at Dana–Farber/Harvard Cancer Center, Boston, MA 02115; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Department of Medical Oncology, 3Belfer Institute for Applied Cancer Science; and 4Departments of Cancer Biology and 5Biological Chemistry and Molecular Pharmacology, Dana Farber Cancer Institute, 6Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and 7Department of Research Pharmacology, Pfizer Global Research and Development, La Jolla, California; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Department of Medical Oncology, 3Belfer Institute for Applied Cancer Science; and 4Departments of Cancer Biology and 5Biological Chemistry and Molecular Pharmacology, Dana Farber Cancer Institute, 6Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and 7Department of Research Pharmacology, Pfizer Global Research and Development, La Jolla, California; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Department of Medical Oncology, 3Belfer Institute for Applied Cancer Science; and 4Departments of Cancer Biology and 5Biological Chemistry and Molecular Pharmacology, Dana Farber Cancer Institute, 6Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and 7Department of Research Pharmacology, Pfizer Global Research and Development, La Jolla, California; Authors' Affiliations: 1Lowe Center for Thoracic Oncology, 2Department of Medical Oncology, 3Belfer Institute for Applied Cancer Science; and 4Departments of Cancer Biology and 5Biological Chemistry and Molecular Pharmacology, Dana Farber Cancer Institute, 6Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and 7Department of Research Pharmacology, Pfizer Global Research and Development, La Jolla, California Division of Hematology and Medical Oncology, Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY 10016, USA 6Department of Medicine, Division of Hematology and Medical Oncology, New York University Langone Medical Center, New York, New York. Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York , NY 10016 , USA 2Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, NYU Langone Health, New York City, New York. 14Division of Hematology and Oncology, New York University School of Medicine, New York, New York. Authors' Affiliations: Departments of 1Medicine, 2Radiology, and 3Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 4Medical Oncology, 5Imaging, and 6Cancer Biology, 7Lowe Center for Thoracic Oncology, and 8Blais Proteomics Center, Dana-Farber Cancer Institute; 9Ludwig Center at Dana-Farber/Harvard Cancer Center; and 10Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and 11Department of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Authors' Affiliations: Departments of 1Medicine, 2Radiology, and 3Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 4Medical Oncology, 5Imaging, and 6Cancer Biology, 7Lowe Center for Thoracic Oncology, and 8Blais Proteomics Center, Dana-Farber Cancer Institute; 9Ludwig Center at Dana-Farber/Harvard Cancer Center; and 10Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and 11Department of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Authors' Affiliations: Departments of 1Medicine, 2Radiology, and 3Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 4Medical Oncology, 5Imaging, and 6Cancer Biology, 7Lowe Center for Thoracic Oncology, and 8Blais Proteomics Center, Dana-Farber Cancer Institute; 9Ludwig Center at Dana-Farber/Harvard Cancer Center; and 10Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and 11Department of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Authors' Affiliations: Departments of 1Medicine, 2Radiology, and 3Biological Chemistry and Molecular Pharmacology, Harvard Medical School; Departments of 4Medical Oncology, 5Imaging, and 6Cancer Biology, 7Lowe Center for Thoracic Oncology, and 8Blais Proteomics Center, Dana-Farber Cancer Institute; 9Ludwig Center at Dana-Farber/Harvard Cancer Center; and 10Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and 11Department of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 2Division of Hematology & Medical Oncology, Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York.; 7Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.; 12Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 2Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York. 2Departments of Medical Oncology and Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts; and 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. Department of Medical Oncology and Belfer Institute for Applied Cancer Science, Dana–Farber Cancer Institute, Boston, MA 02115;; Department of Medicine, Harvard Medical School, Boston, MA 02115; 2Dana-Farber Cancer Institute, Boston, Massachusetts; 1Department of Medical Oncology and Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute;; 2Department of Medicine, Brigham and Women's Hospital and Harvard Medical School; 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.; 4Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts. 3Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York. 1Lowe Center for Thoracic Oncology, Boston, Massachusetts.; 2Department of Medical Oncology, Boston, Massachusetts.; 5Department of Medicine, Boston, Massachusetts.; 6Belfer Institute for Applied Cancer Science, Dana Farber Cancer Institute, Boston, Massachusetts. 8Department of Medicine, New York University School of Medicine, New York, New York. Department of Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115;; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115; and Medical Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115;; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115; and 1Department of Medicine, Dana Farber Cancer Institute, Boston, Massachusetts.; 2Harvard Medical School, Boston, Massachusetts.; 3Ludwig Institute for Cancer, Cambridge, Massachusetts.; 7Belfer Institute for Applied Cancer Science, Boston, Massachusetts. 12Department of Medical Oncology and Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts. Authors' Affiliations: Departments of 1Medical Oncology, 2Cancer Biology, 3Biological Chemistry and Molecular Pharmacology, 4Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; Departments of 5Pathology and 6Medicine, Brigham and Women's Hospital, Boston; 7The Broad Institute, Cambridge, Massachusetts; and 8Pfizer Global Research and Development, Department of Research Pharmacology, La Jolla, California; Authors' Affiliations: Departments of 1Medical Oncology, 2Cancer Biology, 3Biological Chemistry and Molecular Pharmacology, 4Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; Departments of 5Pathology and 6Medicine, Brigham and Women's Hospital, Boston; 7The Broad Institute, Cambridge, Massachusetts; and 8Pfizer Global Research and Development, Department of Research Pharmacology, La Jolla, California; Authors' Affiliations: Departments of 1Medical Oncology, 2Cancer Biology, 3Biological Chemistry and Molecular Pharmacology, 4Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; Departments of 5Pathology and 6Medicine, Brigham and Women's Hospital, Boston; 7The Broad Institute, Cambridge, Massachusetts; and 8Pfizer Global Research and Development, Department of Research Pharmacology, La Jolla, California 1Department of Hematology and Oncology, Langone-Laura and Isaac Perlmutter Cancer Center, New York University, New York, New York. 2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 3Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.; 4Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 8Ludwig Center at Dana-Farber/Harvard Cancer Center, Dana-Farber Cancer Institute, Boston, Massachusetts. 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 3Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115;; Ludwig Center at Dana-Farber/Harvard Cancer Center, Boston, MA 02115;; Departments of dMedicine and 1Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115 Department of Medicine, Dana Farber Cancer Institute, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Ludwig Institute for Cancer, Cambridge, Massachusetts, USA; Belfer Institute for Applied Cancer Science, Boston, Massachusetts, USA 11Division of Hematology and Oncology, New York University, New York, New York. 2Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.; 4Division of Medical Oncology, Perlmutter Cancer Center, NYU Medical School, New York, New York. Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY 10016; Authors' Affiliations: 1Department of Medicine, Harvard Medical School; 2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; 3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts; and 4Howard Hughes Medical Institute, Chevy Chase, Maryland; Authors' Affiliations: 1Department of Medicine, Harvard Medical School; 2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; 3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts; and 4Howard Hughes Medical Institute, Chevy Chase, Maryland Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of 2Medicine and 3Pathology, Brigham and Women's Hospital/Harvard Medical School; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center/Harvard Medical School, Boston, Massachusetts; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of 2Medicine and 3Pathology, Brigham and Women's Hospital/Harvard Medical School; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center/Harvard Medical School, Boston, Massachusetts; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of 2Medicine and 3Pathology, Brigham and Women's Hospital/Harvard Medical School; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center/Harvard Medical School, Boston, Massachusetts Authors' Affiliations: Departments of 1Medicine, 2Biological Chemistry and Molecular Pharmacology, and 3Radiation Oncology; 4Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; 5Department of Medical Oncology; 6Lowe Center for Thoracic Oncology; 7Ludwig Center, Dana-Farber/Harvard Cancer Center; 8Massachusetts General Hospital Cancer Center; 9Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston; 10Agios Pharmaceuticals; 11Broad Institute of MIT and Harvard, Cambridge, Massachusetts; 12Lineberger Comprehensive Cancer Center; 13Department of Medicine and Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 14Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California; 15The University of Texas MD Anderson Cancer Center, Houston, Texas; 16Department of Pediatrics, Columbia University Medical Center, New York, New York; 17Department of Physiology, University of Valencia, Bur; Authors' Affiliations: Departments of 1Medicine, 2Biological Chemistry and Molecular Pharmacology, and 3Radiation Oncology; 4Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; 5Department of Medical Oncology; 6Lowe Center for Thoracic Oncology; 7Ludwig Center, Dana-Farber/Harvard Cancer Center; 8Massachusetts General Hospital Cancer Center; 9Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston; 10Agios Pharmaceuticals; 11Broad Institute of MIT and Harvard, Cambridge, Massachusetts; 12Lineberger Comprehensive Cancer Center; 13Department of Medicine and Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 14Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California; 15The University of Texas MD Anderson Cancer Center, Houston, Texas; 16Department of Pediatrics, Columbia University Medical Center, New York, New York; 17Department of Physiology, University of Valencia, Bur; Authors' Affiliations: Departments of 1Medicine, 2Biological Chemistry and Molecular Pharmacology, and 3Radiation Oncology; 4Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; 5Department of Medical Oncology; 6Lowe Center for Thoracic Oncology; 7Ludwig Center, Dana-Farber/Harvard Cancer Center; 8Massachusetts General Hospital Cancer Center; 9Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston; 10Agios Pharmaceuticals; 11Broad Institute of MIT and Harvard, Cambridge, Massachusetts; 12Lineberger Comprehensive Cancer Center; 13Department of Medicine and Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 14Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California; 15The University of Texas MD Anderson Cancer Center, Houston, Texas; 16Department of Pediatrics, Columbia University Medical Center, New York, New York; 17Department of Physiology, University of Valencia, Bur; Authors' Affiliations: Departments of 1Medicine, 2Biological Chemistry and Molecular Pharmacology, and 3Radiation Oncology; 4Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School; 5Department of Medical Oncology; 6Lowe Center for Thoracic Oncology; 7Ludwig Center, Dana-Farber/Harvard Cancer Center; 8Massachusetts General Hospital Cancer Center; 9Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston; 10Agios Pharmaceuticals; 11Broad Institute of MIT and Harvard, Cambridge, Massachusetts; 12Lineberger Comprehensive Cancer Center; 13Department of Medicine and Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; 14Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California; 15The University of Texas MD Anderson Cancer Center, Houston, Texas; 16Department of Pediatrics, Columbia University Medical Center, New York, New York; 17Department of Physiology, University of Valencia, Bur Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115 Integrated Program in Cellular, Molecular and Biophysical Studies, Columbia University, New York, New York 10032 Authors' Affiliations: 1Marlene and Stewart Greenebaum Cancer Center, 2Department of Pathology, University of Maryland School of Medicine; 3Department of Environmental Health Sciences, Johns Hopkins School of Public Health, Baltimore Maryland; and 4Department of Medicine, Dana-Farber Cancer Institute/Harvard Medical School, Boston, Massachusetts Department of Medical Oncology and 1Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 3Department of Medicine, Harvard Medical School, Boston, Massachusetts.; 6Belfer Center for Applied Cancer Science, Boston, Massachusetts. The Dana Farber Cancer Institute, Boston, Massachusetts; Authors' Affiliations: Departments of 1Molecular and Cellular Oncology and 2Breast Medical Oncology, and 3Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M.D. Anderson Cancer Center; and 4Graduate School of Biomedical Sciences, The University of Texas, Houston, Texas; 5Department of Medicine, Harvard Medical School, Boston, Massachusetts; and 6Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical, University and Hospital, Taichung, Taiwan Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of 2Medicine, 3Pathology, Brigham and Women's Hospital and Harvard Medical School; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Department of Pathology, Harvard Medical School, Boston; 6Synta Pharmaceuticals Corp., Lexington; and 7The Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of 2Medicine, 3Pathology, Brigham and Women's Hospital and Harvard Medical School; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Department of Pathology, Harvard Medical School, Boston; 6Synta Pharmaceuticals Corp., Lexington; and 7The Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of 2Medicine, 3Pathology, Brigham and Women's Hospital and Harvard Medical School; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Department of Pathology, Harvard Medical School, Boston; 6Synta Pharmaceuticals Corp., Lexington; and 7The Broad Institute of MIT and Harvard, Cambridge, Massachusetts Medical Oncology, Dana-Farber Cancer Institute, and Harvard Medical School, Boston, MA; and 4Department of Medicine, Harvard Medical School, Boston, Massachusetts.; 7Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Medical Oncology, Dana–Farber Cancer Institute, Boston, MA 02115; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115; and Departments of Dermatology and Genetics and Medicine, Harvard Medical School, Boston, MA 02115 Authors' Affiliations: Departments of 1Medical Oncology and 2Biological Chemistry and Molecular Pharmacology, Dana-Farber Cancer Institute, Boston; 3The Broad Institute of Harvard and MIT, Cambridge, Massachusetts; and 4Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Authors' Affiliations: 1Center for Advanced Preclinical Research, SAIC-Frederick, Inc., Frederick National Laboratory for Cancer Research/NCI, and 2Mouse Cancer Genetics Program, Frederick National Laboratory for Cancer Research/NCI, Frederick, Maryland; 3Genetics Division and 4Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School; 5Ludwig Center at Dana-Farber/Harvard Cancer Center, Boston, Massachusetts; 6Department of Physiology, University of Valencia, Burjassot, Spain; 7Molecular Imaging Program, National Cancer Institute, NIH, Bethesda, Maryland; 8Broad Institute of MIT and Harvard, Cambridge, Massachusetts; and 9Metabolon, Inc., Durham, North Carolina; Authors' Affiliations: 1Center for Advanced Preclinical Research, SAIC-Frederick, Inc., Frederick National Laboratory for Cancer Research/NCI, and 2Mouse Cancer Genetics Program, Frederick National Laboratory for Cancer Research/NCI, Frederick, Maryland; 3Genetics Division and 4Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School; 5Ludwig Center at Dana-Farber/Harvard Cancer Center, Boston, Massachusetts; 6Department of Physiology, University of Valencia, Burjassot, Spain; 7Molecular Imaging Program, National Cancer Institute, NIH, Bethesda, Maryland; 8Broad Institute of MIT and Harvard, Cambridge, Massachusetts; and 9Metabolon, Inc., Durham, North Carolina 1Department of Medical Oncology, Dana-Farber Cancer Institute;; 5Medicine, Brigham and Women's Hospital, Harvard Medical School; Author's Affiliation: Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215;; Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115;; Ludwig Center at Dana-Farber/Harvard Cancer Center, Boston, MA 02215; and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; 2Department of Medicine, Brigham and Women's Hospital, Harvard Medical School; 3Belfer Institute for Applied Cancer Science; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center; 6Department of Medicine, Harvard Medical School; 7Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; 8Shanghai Jiaotong University School of Medicine, Shanghai, China; and 9Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; 2Department of Medicine, Brigham and Women's Hospital, Harvard Medical School; 3Belfer Institute for Applied Cancer Science; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center; 6Department of Medicine, Harvard Medical School; 7Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; 8Shanghai Jiaotong University School of Medicine, Shanghai, China; and 9Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; 2Department of Medicine, Brigham and Women's Hospital, Harvard Medical School; 3Belfer Institute for Applied Cancer Science; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center; 6Department of Medicine, Harvard Medical School; 7Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; 8Shanghai Jiaotong University School of Medicine, Shanghai, China; and 9Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Authors' Affiliations: 1Department of Medical Oncology, Dana-Farber Cancer Institute; 2Department of Medicine, Brigham and Women's Hospital, Harvard Medical School; 3Belfer Institute for Applied Cancer Science; 4Ludwig Center at Dana-Farber/Harvard Cancer Center; 5Massachusetts General Hospital Cancer Center; 6Department of Medicine, Harvard Medical School; 7Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; 8Shanghai Jiaotong University School of Medicine, Shanghai, China; and 9Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 2Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; 3Harvard Medical School, Boston, Massachusetts.; 4Belfer Center for Applied Science, Dana-Farber Cancer Institute, Boston, Massachusetts. 2Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.; 3Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.; 12Belfer Institute for Applied Cancer Science, Dana Farber Cancer Institute, Boston, Massachusetts. *Department of Medical Oncology and; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115; 11Department of Hematology and Oncology, New York University Langone Medical School, New York, New York. Authors' Affiliations: Departments of 1Medical Oncology and 2Cancer Biology, Dana-Farber Cancer Institute; 3Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston; 4Broad Institute of Harvard and MIT, Cambridge; 5MGH Cancer Center, 6Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, Massachusetts; and 7Department of Surgery, Division of Biology and Biomedical Sciences, Washington University, St. Louis, Missouri 6Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center New York, New York. Authors' Affiliations: 1Belfer Institute for Applied Cancer Science;; 2Department of Medical Oncology, Dana-Farber Cancer Institute; and 2Department of Medical Oncology, Dana-Farber Cancer Institute; and; 3Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 19Laura and Isaac Perlmutter Cancer Center, Division of Hematology and Medical Oncology, New York University, New York, New York. Dana-Farber Cancer Institute, Harvard Medical School, Dana Building 810B, HIM243, Boston, MA 02115, USA Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center , New York , NY 10016 , USA 3Department of Medical Oncology, Dana-Farber Cancer Institute,; 6Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; and |
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