http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_0bed0bfc038d105c632b616d06eddac1
Outgoing Links
Predicate | Object |
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family-name | Peng Huang Huang |
name | Peng Huang |
given-name | Peng |
organization-name | Department of Cardiothoracic Surgery, Hunan Children's Hospital Institute of Microelectronics, Peking University, Beijing 100871, China Hunan Children's Hospital, Changsha 410007, Hunan, China. School of Control Science and Engineering, Shandong University, Jinan 250061, Shandong, China Department of Military Medical Psychology Air Force Medical University Xi'an China Shanghai Culture and Sports Promotion Center for Persons with Disabilities, Shanghai, China College of Ocean and Earth Sciences, Xiamen University, Xiamen 361102, China; College of Ocean and Meteorology, Guangdong Ocean University, Zhanjiang 524088, China College of Food Science, Sichuan Agricultural University, Ya’an 625014, China; Department of Quality Management and Inspection and Detection, Yibin University, Yibin 644000, China 6Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston Texas. Institute of Microelectronics Peking University Beijing 100871 P. R. China Department of Cardiothoracic surgery, Hunan Children's Hospital, Changsha, China. [email protected] Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410007, China. [email protected] Suzhou Cancer Center Core Laboratory, Suzhou Municipal Hospital, Gusu School The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou China School of Chemistry; University of Bristol; Bristol, UK Central South University of Forestry and Technology Changsha China Institute of Plant Protection, Fujian Academy of Agricultural Sciences, Fuzhou, Fujian, P.R. China; Fujian Key Laboratory for Monitoring and Integrated Management of Crop Pests, Fuzhou, Fujian, P.R. China Laboratory of Molecular Imaging and Nanomedicine (LOMIN) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institutes of Health (NIH) Bethesda MD 20892 USA Department of Epidemiology , National Vaccine Innovation Platform, Center for Global Health, School of Public Health, , Nanjing , China; Nanjing Medical University , National Vaccine Innovation Platform, Center for Global Health, School of Public Health, , Nanjing , China Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Okayama Medical Innovation Center, Okayama University, Okayama, Japan Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, School of Mechanical Engineering, Southeast University, Nanjing, People's Republic of China. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China; School of Pharmaceutical Sciences, Sun Yat-sen University, 132 Waihuan Road, Guangzhou 510006, China Laboratory of Molecular Imaging and Nanomedicine (LOMIN); National Institute of Biomedical Imaging and Bioengineering (NIBIB); National Institutes of Health (NIH); Bethesda, United States; Department of Biomedical Engineering Laboratory of Advanced Optoelectronic Materials, College of Chemistry Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, College of Life Sciences, Peking University, Beijing, 100871, P. R. China. Tibet Rhodiola Pharmaceutical Holding Company , Lhasa , China Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen 518060, China. Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, PR China; Key Laboratory of Infectious Diseases, School of Public Health, Nanjing Medical University, Nanjing, PR China Hunan Agricultural University College of Animal Science and Technology, , Changsha 410128, Hunan, China Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Guangxi Medical University, Nanning 530021, China Department of Molecular and Cellular Oncology, M. D. Anderson Cancer Center, The University of Texas, Houston, TX;; Molecular Pathology, and Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA 19140, U.S.A. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China;; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA Department of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College 17 Panjiayuannanli, Chaoyang District Beijing 100021 China Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410006, China [email protected]. 1Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center and; 2The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas and Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Chemistry and Life Sciences Zhejiang Normal University Jinhua Zhejiang China College of Mechanical and Electrical Engineering, Sichuan Agriculture University, Ya’an 625014, China Department of Experimental Pharmacology and Toxicology Jilin University Changchun Jilin China Institute of Information Science and Engineering, Guilin University of Technology, Guilin 541004, China Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, China Department of Emergency Medicine Nanfang Hospital, Southern Medical University Guangzhou China Department of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230012, P.R. China Department of Bio-Nano Science and Engineering; Research Institute of Micro/Nano Science and Technology; Shanghai Jiao Tong University; Shanghai 200240, P. R. China Laboratory of Advanced Optoelectronic Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China Prenatal Diagnostic Center, Guangxi Zhuang Autonomous Region Women and Children Care Hospital, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 1Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.; 5Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Institute of Pharmacology, Toxicology and Biological Pharmaceutics, Zhejiang University, Hangzhou, 310058, China. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University, Shenzhen 518060, China Nanjing University of Science and Technology Authors' Affiliations: 1Houston Methodist Research Institute; 2The University of Texas M.D. Anderson Cancer Center, Houston, Texas; 3Hematology Branch, National Heart Lung and Blood Institute (NHLBI); 4National Center for Advancing Translational Sciences, NIH, Bethesda, Maryland; 5The University of Kansas Medical Center; 6Institute for Advancing Medical Innovation, Kansas University, Kansas City, Kansas; 7Division of Hematology, Department of Internal Medicine, The Comprehensive Cancer Center at the Ohio State University, Columbus, Ohio; and 8Weill Cornell Medical College, New York, New York Department of General Surgery, Xiangya Hospital, Central South University China. SKCCC Oncology Biostatistics Division, School of Medicine, Johns Hopkins University, Baltimore, Maryland, U.S.A. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou Guangdong 510060 P. R. China; Metabolic Innovation Center Sun Yat‐sen University Guangzhou Guangdong 510080 P. R. China Oncology Biostatistics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD College of Chemistry; Chemical Engineering and Materials Science; Soochow University; Suzhou; China Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland 20892, United States Institute of Plant Stress Adaptation and Genetic Enhancement, Zhejiang Normal University , Jinhua 321004, China; Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, Department of Biology, College of Chemistry and Life Sciences, Zhejiang Normal University , Jinhua 321004, China Department of Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; and Department of Pediatric Orthopaedics, National Children's Medical Center Children's Hospital of Fudan University Shanghai China Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland 20892, United States; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen, 518060 Guangdong, P.R. China Department of Experimental Pharmacology and Toxicology, School of Pharmacy, Jilin University , Changchun , China Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas; and The Graduate School of Biomedical Sciences, The University of Texas at Houston, Houston, Texas College of Chemistry, Chemical Engineering and Materials Science, and ‡Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China From the Departments of Molecular Pathology, Experimental Therapeutics, and Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, TX. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen 518060, China; Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland 20892, United States Department of Civil Engineering The University of Hong Kong, Research Student Center, Haking Wong Building Pokfulam Hong Kong State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Agriculture, Nanjing Agricultural University, Nanjing, China Department of Cardiology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shangdong 264000, P.R. China Department of General Surgery Xiangya Hospital Central South University China Key Laboratory of Cell Proliferation and Differentiation of the Ministry of Education, College of Life Sciences, Peking University, Beijing 100871, P. R. China and 2Department of Molecular, Cell & Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, P. R. China; State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, P. R. China Center for Substance Abuse Research and Department of Pharmacology, Temple University School of Medicine, 3500 N. Broad Street, MERB 851, Philadelphia, PA, 19140, USA. Department of Translational Molecular Pathology; Division of Pathology and Laboratory Medicine; University of Texas MD Anderson Cancer Center; USA Department of Oncology, The Second Affiliated Hospital JiangXi Medical College, Nanchang University Nanchang China; JiangXi Key Laboratory of Clinical and Translational Cancer Research Nanchang China Marshall Laboratory of Biomedical Engineering International Cancer Center Laboratory of Evolutionary Theranostics (LET) School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen 518060 P. R. China Boston University Department of Mechanical Engineering, , Boston, Massachusetts 02215, USA BCMaterials, Basque Center for Materials, Applications and Nanostructures, Martina Casiano, UPV/EHU Science Park, 48940 Leioa, Spain; Research Institute of Frontier Science, Southwest Jiaotong University, 610031 Chengdu, China Prostate Cancer Research Program Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland Department of Neurosurgery, Center for Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Epidemiology School of Public Health, Nanjing Medical University Nanjing China Department of Experimental Pharmacology and Toxicology, School of Pharmacy Jilin University Changchun Jilin China Kidney Disease of Internal, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China MIIT Key Laboratory for Low-Dimensional Quantum Structure and Devices, School of Materials Science & Engineering, Beijing Institute of Technology, Beijing 100081, China Institute of Nano Biomedicine and Engineering; Shanghai Engineering Research Center for Intelligent diagnosis and treatment instrument; Department of Instrument Science and Engineering; School of Electronic Information and Electrical Engineering; Shanghai Jiao Tong University Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering Health Science Center, Shenzhen University Shenzhen China Department of Oncology, Division of Quantitative Science, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Department of Pharmacology and Center for Substance Abuse Research and Fels Institute for Molecular Biology and Cancer Research, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, and Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York 10029 Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China Heart Center Department of Pharmacology and Toxicology, Jilin University School of Pharmaceutical Sciences, 1163 Xinmin Ave, Changchun 130021, China Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Guangzhou Key Laboratory of Inflammatory and Immune Diseases, Zhujiang Hospital, Southern Medical University, Guangzhou, China.; Department of Urology, Okayama Medical Innovation Center, Okayama University, Okayama, Japan. Authors' Affiliations: Departments of 1Oncology, 2Surgery, and 3Pathology, Johns Hopkins University School of Medicine; 4Department of Epidemiology, Bloomberg School of Public Health, Baltimore, Maryland; 5Department of Surgery, Duke University School of Medicine, Durham, North Carolina; 6Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan; and 7Biomedical Engineering, Oregon Health Sciences University, Portland, Oregon Guangdong Engineering and Technology Research Centre for Advanced Nanomaterials School of Environment and Civil Engineering Dongguan University of Technology Dongguan 523808 P. R. China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen 518060, China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou People's Republic of China; Department of Experimental Research Sun Yat‐sen University Cancer Center Guangzhou People's Republic of China State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China; Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA 1Molecular Pathology and Departments of Laboratory of Molecular Imaging and Nanomedicine (LOMIN); National Institute of Biomedical Imaging and Bioengineering (NIBIB); National Institutes of Health (NIH); Bethesda, USA Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering Shenzhen University Shenzhen 518060 P.R. China Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China Peng Huang, PhD, is Associate Professor, Department of Biostatistics, Bioinformatics and Epidemiology, College of Graduate Studies, Medical University of Charleston, Charleston Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Okayama Medical Innovation Center, Okayama University, Okayama, Japan Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital, Harbin Medical University, Harbin, China; The Key Laboratory of Myocardial Ischemia, Harbin Medical University, Ministry of Education, Harbin, China School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, P.R. China; State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou 510275, P.R. China 1Molecular Pathology; Departments of Center for Evidence‐Based Medicine School of Public Health Nanchang University Nanchang China; Jiangxi Province Key Laboratory of Preventive Medicine School of Public Health Nanchang University Nanchang China From the Departments of Molecular Pathology, Cancer Biology, and Leukemia, the University of Texas M. D. Anderson Cancer Center, Houston, TX. Henan Institute of Advanced Technology, College of Chemistry Zhengzhou University Zhengzhou 450001 P.R. China Department of Biometry and Epidemiology, Medical University of South Carolina (MUSC), Charleston, South Carolina Dept of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina, Charleston, SC, USA Marshall Laboratory of Biomedical Engineering International Cancer Center Laboratory of Evolutionary Theranostics School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen 518060 China Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, P. R. China Johns Hopkins School of Medicine; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD Western Digital Technologies 1 , Irvine, California 92612, USA Department of Pharmacology and Center for Substance Abuse Research and Fels Institute for Molecular Biology and Cancer Research, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, and Center for Molecular Recognition, Columbia University College of Physicians and Surgeons, New York, New York 10029 Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials; Department of Chemistry, School of Chemistry and Chemical Engineering; Jiangsu Normal University; Xuzhou; P. R. China Department of Gastrointestinal Oncology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province, China State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China School of Environmental Studies, China University of Geosciences, Lumo road 388#, Hongshan district, Wuhan, Hubei 430074, China Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland 20892, United States; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen 518060, China 1Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, China. College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005, China Laboratory of Molecular Imaging and Nanomedicine (LOMIN); National Institute of Biomedical Imaging and Bioengineering (NIBIB); National Institutes of Health (NIH); Bethesda MD 20892 USA Beijing Key Laboratory of Nanophotonics and Ultrafine Optoelectronic Systems School of Materials Science & Engineering Micro Nano Technology Center School of Physics Beijing Institute of Technology 5 Zhongguancun South Street, Haidian District Beijing 100081 China 1Sidney Kimmel Cancer Center, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.; 6Department of Biostatistics, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Laboratory of Molecular Imaging and Nanomedicine (LOMIN); National Institute of Biomedical Imaging and Bioengineering (NIBIB); National Institutes of Health; Bethesda, USA Shanghai Jiaotong University Center for Substance Abuse Research and Department of Pharmacology, Temple University Lewis Katz School of Medicine, Philadelphia, PA 19140, U.S.A. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng East Road, Guangzhou 510060, China Department of Hepatopancreatobiliary Surgery,Second Affiliated Hospital of Harbin Medical University,Harbin,China; The Key Laboratory of Myocardial Ischemia,Ministry of Education,Harbin Medical University,Harbin,China Center for Evidence‑Based Medicine, School of Public Health, Nanchang University, Nanchang, Jiangxi 330006, P.R. China College of Life Sciences, Zhejiang Normal University, Jinhua 321004, China Department of Emergency, Tengzhou Hospital of Traditional Chinese Medicine Tengzhou 277500, Shandong, China. Department of Otolaryngology of Binzhou Centre Hospital, Binzhou 251700, China. Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Sun Yat-sen University; Guangzhou 510060 Department of Neurosurgery, Center for Functional Neurosurgery, RuiJin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine Shanghai China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, China Chinese PLA General Hospita,the Fourth Medical Center,Department of Orthopedics,Beijing,China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging School of Biomedical Engineering Shenzhen University Shenzhen 518060 P. R. China Beijing Key Laboratory of Nanophotonics and Ultrafine Optoelectronic Systems School of Materials Science & Engineering Beijing Institute of Technology Beijing 100081 China Authors' Affiliations: 1Department of Biochemistry, Nagoya University Graduate School of Medicine; 2Department of Computer Science/Scientific and Engineering Simulation, Nagoya Institute of Technology, Nagoya; and 3Transgenic Animal Research Center, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki, Japan Department of Paediatric Orthopaedics, National Center for Children’s Health, Children’s Hospital of Fudan University, Minhang District, Shanghai 201102, China Fudan University Department of Orthopedic Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH. Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China; Key Laboratory of Infectious Diseases, School of Public Health, Nanjing Medical University, Nanjing, China Sun Yat‐Sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China; Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Burns and Reconstructive Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng East Road, Guangzhou 510060, China Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892 State Key Laboratory of Oncology in South China; Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine; Guangzhou China; Department of Translational Molecular Pathology; University of Texas M.D. Anderson Cancer Center; Houston TX USA State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, 2999 North Renmin Road, Shanghai 201620, People’s Republic of China Division of Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA; Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, P. R. China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou 510060 Guangdong P. R. China Authors' Affiliations: 1State Key Laboratory of Oncology in Southern China and Departments of 2Experimental Research and 3Medical Oncology, Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong, China; and 4School of Engineering, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China; Authors' Affiliations: 1State Key Laboratory of Oncology in Southern China and Departments of 2Experimental Research and 3Medical Oncology, Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong, China; and 4School of Engineering, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China Department of Pharmacology and Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA 19140, USA. [email protected] Collaborative Innovation Center for Biomedicine, School of Clinical Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, China College of Chemistry Liaoning University 110036 Shenyang Liaoning China; Judicial Authentication & Forensic Sciences Institute Liaoning University 110036 Shenyang Liaoning China Department of Pharmacology and Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA 19140 Department of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H 4R2, Canada; Chongming Hospital, Shanghai University of Medicine and Health Sciences, Shanghai 202150, China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials; College of Materials Science and Engineering; Donghua University; Shanghai 201620; P. R. China Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Shanghai Disabled Persons' Sport Training Center, Shanghai 200083. Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX; The College of Pharmacy; Anhui University of Chinese Medicine; Hefei; China Liver Center and Gastrointestinal Division,Department of Medicine,Massachusetts General Hospital,Harvard Medical School,Boston,MA Center for Evidence-based Medicine; Jiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang, China. State Key Laboratory of Microbial Metabolism School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai 200240 China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen China Animal Nutritional Genome and Germplasm Innovation Research Center, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha 410007, China. Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100021, China; State Key Laboratory of Molecular Oncology, National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA School of Sports Medicine and Physical Therapy, Beijing Sport University, Beijing, P. R. China Key Laboratory of Automobile Materials; Ministry of Education; and College of Materials Science and Engineering; Jilin University; Changchun 130022 Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas. Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA The College of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui, China; College of Chemistry, Chemical Engineering and Materials Science Soochow University Suzhou 215123 China Department of Mechanical Engineering, Boston University 1 , Boston, Massachusetts 02215, USA Department of General Surgery, The First Hospital of China Medical University, Shenyang - China State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing 210095, China Department of Molecular and Cellular Biology, Center for Brain Science,Harvard Stem Cell Institute, Broad Institute, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA. 6Molecular Pathology, University of Texas M. D. Anderson Cancer Center; Department of Urology, Guizhou Provincial People's Hospital Guiyang 550002, Guizhou, China. State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou 510060 China School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China; Foshan Maternal and Child Health Research Institute, Affiliated Hospital of Southern Medical University, Foshan, Guangdong, China State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou China Department of General Surgery, The Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Changsha 410013, China Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada. 2Molecular Pathology, Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston Laboratory of Molecular Imaging and Nanomedicine (LOMIN); National Institute of Biomedical Imaging and Bioengineering (NIBIB); National Institutes of Health (NIH); Bethesda; USA National Institute of Biomedical Imaging and Bioengineering (NIBIB); National Institutes of Health (NIH); Bethesda, USA State Key Laboratory of Physical Chemistry of Solid Surfaces and College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, People’s Republic of China. The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging; Department of Biomedical Engineering; School of Medicine; Shenzhen University; Shenzhen 518060 Marshall Laboratory of Biomedical Engineering International Cancer Center Laboratory of Evolutionary Theranostics (LET) School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen 518060 China Key Laboratory of Automobile Materials Ministry of Education and College of Materials Science and Engineering Jilin University Changchun 130022 P. R. China Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, TX Department of Experimental Pharmacology and Toxicology, School of Pharmacy, Jilin University, Changchun, China Department of Pediatrics, South Medical University Affiliated Maternal and Child Health Hospital of Foshan, Foshan, Guangdong 528000, P.R. China Bioscience and Biotechnology Center Nagoya University Nagoya 464‐8601 Japan; State Key Laboratory of Crop Genetics and Germplasm Enhancement Nanjing Agricultural University Nanjing 210095 China Key Laboratory of Zoonosis, Jilin University, Changchun, China Center for Regenerative Medicine and Department of Laboratory Medicine and Pathology, Mayo Clinic Jacksonville Florida USA Department of Radiology, Zhongshan Hospital Fudan University Shanghai China; Department of Cancer Center Zhongshan Hospital, Fudan University Shanghai China Jiangsu Key Laboratory for Design and Manufacture of Micro‐Nano Biomedical Instruments School of Mechanical Engineering Southeast University Nanjing 211189 P. R. China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, China Marshall Laboratory of Biomedical Engineering, International Cancer Center, Shenzhen Key Laboratory of Tumor Visualization Molecular Medicine, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518055, China. Department of Gastrointestinal Oncology, Harbin Medical University Cancer Hospital, Harbin 150081, China Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Alberta, Canada Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland 20892, United States; Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, China Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.; Key Laboratory of Infectious Diseases, School of Public Health, Nanjing Medical University, Nanjing, China. State Key Laboratory of Tribology, Tsinghua University, Beijing100084, China Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan; Okayama Medical Innovation Center, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan Medical University of South Carolina, Charleston Department Institute of Functional Material Chemistry, Key Lab of Polyoxometalate Science of Ministry of Education, Department of Chemistry, Northeast Normal University, Changchun 130024, P. R. China Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; State Key Laboratory of Oncology in Southern China, Sun Yat-Sen University Cancer Center, Guangzhou, China. Department of Orthopaedic Surgery, PLA General Hospital, Beijing,100853, PR China. School of Clinical Medicine, Shanghai College of Medical and Health Sciences, Shanghai 201318, China. Prenatal Diagnostic Center, Institute of Birth Defect Prevention and Control, Guangxi Zhuang Autonomous Region Women and Children Care Hospital, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; Division of Hematology and Department of Experimental Pharmacology and Toxicology School of Pharmacy Jilin University Changchun China Department of General Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an Jiaotong University, PR China; Department of General Surgery, Shaanxi Provincial Corps Hospital of Chinese People’s Armed Police Force, Xi’an, Shaanxi, PR China Department of Thoracic Cardiac Surgery, Hunan Children's Hospital, Changsha, Hunan, China Division of Hematology, Children’s Hospital of Philadelphia, Philadelphia, PA; Department of Orthopaedics General Hospital of Chinese People's Liberation Army Beijing P. R. China Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangzhou 510060; China Department of Respiratory Medicine Zhuzhou Central Hospital Zhuzhou Hunan China College of Basic Medicine, Shanghai University of Medicine and Health Sciences, Shanghai 201318, China. *Corresponding authors, E-mail: [email protected]. State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China Okayama Medical Innovation Center, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences. Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston;; The University of Texas Graduate School of Biomedical Sciences at Houston; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Tokyo 163‑8001, Japan School of Basic Medicine, Shanghai College of Medicine and Health Sciences, Shanghai 201318, China. Department of Pharmacology and Center for Substance Abuse Research and Fels Institute for Molecular Biology and Cancer Research, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York, and Center for Molecular Recognition, Columbia University College of Physicians and Surgeons, New York, New York College of Chemistry & Green Catalysis Center Zhengzhou University Zhengzhou Henan 450001 P. R. China Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials; Department of Chemistry; School of Chemistry and Material Science; Jiangsu Normal University; Xuzhou Department of Pharmacology Center for Substance Abuse Research Temple University School of Medicine Philadelphia PA USA 3Molecular Pathology, and Key Laboratory of Synthetic Rubber, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences From the Departments of Clinical Investigation and Hematology, The University of Texas MD Anderson Cancer Center, Houston. Department of Gastrointestinal Oncology Harbin Medical University Cancer Hospital, Harbin Medical University Harbin Heilongjiang China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China; Department of Translational Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA Xiangya Hospital, Central South University, Changsha, Hunan, China Department of General Surgery, Xiangya Hospital, Central South University Xiangya Road, Changsha, Hunan 410008, China. Department of Chemistry, Key Laboratory for Preparation and Application of Ordered Structural Material of Guangdong Province, and Guangdong Provincial Key Laboratory of Marine Disaster Prediction and Prevention, Shantou University, Shantou, Guangdong, 515063, China Department of Urology The First Affiliated Hospital of Fujian Medical University Fuzhou China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, China; Center for Cancer Metabolism and Intervention Research, Sun Yat-sen University Cancer Center, Guangzhou, China College of Chemistry and Life Science, Sichuan Provincial Key Laboratory for Structural Optimization and Application of Functional Molecules, Chengdu Normal University Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging School of Biomedical Engineering, Health Science Center, Shenzhen University Shenzhen, 518060 China Laboratory of Molecular Imaging and Nanomedicine (LOMIN) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institutes of Health Bethesda MD 20892 USA State Key Laboratory of Oncology in Southern China Collaborative Innovation Center for Cancer Medicine Sun Yat‐Sen University Cancer Center Guangzhou China BCMaterials, Basque Center for Materials, Applications and Nanostructures, Martina Casiano, UPV/EHU Science Park, 48940 Leioa, Spain Department of Pharmacology, Zhejiang University School of Medicine, Hangzhou 310058, China. Department of Molecular and Cellular Biology, Broad Institute/Center for Brain Science, Harvard Stem Cell Institute/Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China; College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, People’s Republic of China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging School of Biomedical Engineering, Health Science Center Shenzhen University Shenzhen 518060 China School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, China Exercise Biological Center, China Institute of Sport Science, Beijing 100061, China; School of Exercise and Health, Shanghai University of Sport, Shanghai 200438, China State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Sun Yat-sen University Cancer Center; Guangzhou 510060; China Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China College of Chemistry, Liaoning University, Shenyang, Liaoning 110036, P. R. China; Judicial Authentication & Forensic Sciences Institute, Liaoning University, Shenyang, Liaoning 110036, P. R. China Institute of Microelectronics Peking University No.5 Yiheyuan Road Haidian District Beijing 100871 P. R.China Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean Energy Hunan University Changsha 410082 China Department of Laboratory Medicine and Pathology Mayo Clinic Jacksonville Florida USA Department of Experimental Pharmacology and Toxicology, School of Pharmaceutical Sciences Jilin University Changchun China College of Food Science, Sichuan Agricultural University, Yaan 625014, China; Department of Quality Management and Inspection and Detection, Yibin University, Yibin 644000, China Center for Substance Abuse Research and Department of Pharmacology, Temple University Lewis Katz School of Medicine, Philadelphia, PA, USA. Department of Oncology; Biostatistics and Bioinformatics Division, School of Medicine and Department of Biostatistics, Bloomberg School of Public Health, The Johns Hopkins University; Baltimore MD USA; Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins University School of Medicine; Baltimore MD USA Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA; Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China School of Integrated Circuit Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China Center for Substance Abuse Research, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania 19140, United States Department of Cell Biology and Anatomy, Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging; Department of Biomedical Engineering; School of Medicine; Shenzhen University; Shenzhen 518060, China Department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China; Sicence and Technology on Surface Physics and Chemistry Laboratory, Mianyang 621908, Sichuan, China Department of Cardiology, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging School of Biomedical Engineering Health Science Center Shenzhen University Shenzhen 518060 China College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, Hunan, P. R. China Anhui University of Chinese Medicine, College of Pharmacy, Hefei, 230012, Anhui, China 1Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center;; 2Graduate School of Biomedical Sciences, The University of Texas at Houston, Houston, Texas; and Department of Orthopaedic Surgery, People's Liberation Army General Hospital, Beijing 100853, China. College of Information Science and Technology, Nanjing Forestry University, Nanjing, China Institute of Nano Biomedicine and Engineering, Key Laboratory for Thin Film and Microfabrication Technology of the Ministry of Education, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China Institute of Functional Material Chemistry, Key Laboratory of Polyoxometalate Science of Ministry of Education, Northeast Normal University, Changchun, 130024 Jilin, People’s Republic of China Ruian People’s Hospital, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China Department of Molecular Pathology University of Texas MD Anderson Cancer Center Houston Texas Department of Respiratory Medicine, Zhuzhou Central Hospital, Zhuzhou, Hunan, China Department of Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Epidemiology, Nanjing Medical University, Nanjing 211166, China; Key Laboratory of Infectious Diseases, Nanjing Medical University, Nanjing 211166, China Department of Nephrology, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000 Guangxi, Guangxi Zhuang Autonomous Region, China Institute of Functional Materials Chemistry, Key Laboratory of Polyoxometalate Science of Ministry of Education, Department of Chemistry, Northeast Normal University, Changchun 130024, People's Republic of China School of Basic Medicine, Shanghai University of Medical and Health Sciences, Shanghai 201318, China. Department of Cardiothoracic Surgery, Hunan Children's Hospital, Changsha, Hunan Department of Radiation Oncology Cancer Institute & Hospital Chinese Academy of Medical Sciences Beijing China Director, Department of Molecular Imaging Chief, Laboratory of Evolutionary Theranostics (LET) Distinguished Professor, School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen, Guangdong 518060, China Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, P.R. China Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, United States College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging Department of Biomedical Engineering School of Medicine Shenzhen University Shenzhen 518060 China State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Sun Yat‐sen University Cancer Center Guangzhou 510060 China Hunan Children’s Hospital, Changsha, China Chongming Hospital, Shanghai University of Medicine and Health Sciences, Shanghai, China; Department of Physiology and Biophysics, Dalhousie University, Halifax, Nova Scotia, Canada Shanghai Aure Technology Limited Company, Shanghai 201800, China School of Mechanical Engineering Nanjing University of Science and Technology Nanjing Jiangsu 210094 China Department of General Surgery, Central South University, Changsha, China. Department of Epidemiology, School of Public Health, Nanchang University, Nanchang, P.R. China.; Jiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang, P.R. China. Department of Pediatrics, Second Xiangya Hospital, Central South University, Changsha 410011. [email protected]. Children's Brain Development and Brain Injury Research Office, Second Xiangya Hospital, Central South University, Changsha 410011, China. [email protected]. State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China Academy of Sports Medicine and Physiotherapy, Beijing Sport University Beijing, China Department of Urology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350004, China. Shenzhen University Health Science Center; Shenzhen 518060 China; School of Biomedical Engineering; Shenzhen University; Shenzhen 518060 China Key Lab Eco-Functional Polymer Materials of MOE, Institute of Polymer, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China Division of Oncology Biostatistics, Johns Hopkins University, Baltimore, Maryland, USA. [email protected] School of Mechanical Engineering, Southeast University, Nanjing 211189, People’s Republic of China National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College 17 Panjiayuannanli Chaoyang District, Beijing 100021 China Department of Psychology, School of Aerospace Medicine, Fourth Military Medical University, Xi'an, China Sun Yat‐sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou Guangdong 510060 P. R. China; Metabolic Research Platform Center for Precision Medicine Zhongshan School of Medicine Sun Yat‐sen University Guangzhou Guangdong 510080 P. R. China Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, No.50 Yikesong Road, Haidian District, 100093 Beijing, P.R. China Department of Pharmacology and Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, and Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York, New York 10029 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China. Department of General Surgery, Xiangya Hospital, Central South University, China Department of Pancreatic Surgery, First Hospital of China Medical University, Shenyang 110001, China. 1Department of Hepatopancreatobiliary Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin, China.; 2The Key Laboratory of Myocardial Ischemia, Harbin Medical University, Ministry of Education, Harbin, China. Department of Orthopaedics, PLA General Hospital, Beijing 100853, China. School of Public Health, Central South University, Changsha 410078, China. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging; School of Biomedical Engineering; Shenzhen University; Shenzhen; P. R. China Institute for Advanced Interdisciplinary Research (iAIR); Collaborative Innovation Center of Technology and Equipment for Biological Diagnosis and Therapy in Universities of Shandong; School of Chemistry and Chemical Engineering; University of Jinan; Jinan 250022 Center for Evidence‐Based Medicine, School of Public Health Nanchang University Nanchang Jiangxi P. R. China; Jiangxi Province Key Laboratory of Preventive Medicine, School of Public Health Nanchang University Nanchang P. R. China College of Materials Science and Engineering; Hunan University; Changsha; China Department of Stereotactic and Functional Neurosurgery, Ruijin Hospital, Shanghai, Jiao Tong University School of Medicine, Shanghai, China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China Department of Urology, Okayama University, Okayama 700‑8558, Japan Foshan Maternal and Child Health Research Institute Affiliated Hospital of Southern Medical University Foshan China Department of Experimental Therapeutics Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine 651 Dong Feng East Road Guangzhou 510060 Guangdong P. R. China; Metabolic Innovation Center, Zhongshan School of Medicine Sun Yat‐sen University Guangzhou 510080 Guangdong P. R. China Department of Functional Neurosurgery, Ruijin Hospital, Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China From the Division of Hematology-Oncology, The Ohio State University, Columbus; Department of Molecular Pathology, University of Texas, MD Anderson Cancer Center, Houston; and Protein Design Labs Inc, Fremont, CA. §Department of Orthopaedics, Chinese People’s Liberation Army General Hospital, Beijing; Department of Neurosurgery, Affiliated Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Orthopedics 452nd Hospital of Chinese PLA Chengdu Sichuan 610021 China Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 210000, China Yale University School of Medicine, Department of Genetics, I-354 SHM, PO Box 208005, New Haven, CT 06520-8005, USA Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging School of Biomedical Engineering Shenzhen University Shenzhen 518060 China Department of Experimental Pharmacology and Toxicology, School of Pharmacy Jilin University Changchun China 5Departments of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, Texas. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA Department of Pharmacology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, United States; Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, United States Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P.R. China Department of Pharmacy, Affiliated Foshan Maternity & Child Healthcare Hospital, Southern Medical University, Foshan 528000, China State Key Laboratory of Oncology in South China, Cancer Metabolism and Intervention Research Center, Sun Yat-Sen University Cancer Center, Guangzhou510060, China; Metabolic Innovation Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou510080, China Marshall Laboratory of Biomedical Engineering International Cancer Center Laboratory of Evolutionary Theranostics (LET) School of Biomedical Engineering Shenzhen University Medical School Shenzhen 518060 China MIIT Key Laboratory for Low Dimensional Quantum Structure and Devices, School of Materials Sciences and Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing 100081, P.R. China Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangzhou 510060, China Department of Orthopaedics Surgery, Children’s Hospital of Fudan University, Minhang District, Shanghai Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China; Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangzhou, Guangdong 510515, China; Key Laboratory of Mental Health of the Ministry of Education, Southern Medical University, Guangzhou, Guangdong 510515, China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging; Laboratory of Evolutionary Theranostics; School of Biomedical Engineering; Health Science Center; Shenzhen University College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China Key Laboratory of Textile Fiber and Products, Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Intelligent Textile Materials & Application, Wuhan Textile University, Wuhan 430200, China Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland) Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China; The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China Department of Spine Surgery, Second Affiliated Hospital of Harbin Medical University, Haerbin, Hei Long Jiang 150086, PR China; Department of Spine Surgery, China Orthopaedics Department, Pla General Hospital Beijing 100083, PR China Department of Functional Neurosurgery, Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520-8005, USA Okayama Medical Innovation Center, Okayama University Okayama, Japan. Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore Department of Materials, University of Manchester, Manchester M13 9PL, U.K. College of Chemistry, Liaoning University, Shenyang, 110036, China Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX; and Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA Center for Evidence‐based Medicine, School of Public Health Nanchang University Nanchang China; Jiangxi Province Key Laboratory of Preventive Medicine, School of Public Health Nanchang University Nanchang China Department of Neurology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China; Hunan Key Laboratory of Traditional Chinese Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China Departments of Molecular Pathology and Department of Molecular Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, Jiangsu 215123, China School of Pharmacy Anhui University of Chinese Medicine Hefei China School of Pharmacy, Anhui University of Chinese Medicine, Hefei, China; Anhui Province Key Laboratory of Research and Development of Chinese Medicine, Hefei, China Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials; Department of Chemistry; School of Chemistry and Chemical Engineering; Jiangsu Normal University; Xuzhou School of Clinical Medicine, Shanghai College of Medicine and Health Sciences, Shanghai 201318, China. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging Carson International Cancer Center Laboratory of Evolutionary Theranostics School of Biomedical Engineering Health Science Center Shenzhen University Shenzhen 518060 China Authors' Affiliations: 1Massachusetts General Hospital Cancer Center, Boston, Massachusetts; 2Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; 3Center for Clinical Innovation, Parkland Health and Hospital System; 4ProPath, Dallas, Texas 5Inostics, GmbH, Hamburg, Germany; and 6GlaxoSmithKline, Oncology R&D, Collegeville, Pennsylvania Marshall Laboratory of Biomedical Engineering International Cancer Center Laboratory of Evolutionary Theranostics (LET) School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen Guangdong 518060 P. R. China School of Engineering and Physical Sciences; Heriot-Watt University; Edinburgh; UK Institute for Laser Medicine & Biophotonics, School of Life Sciences and Biotechnology, and National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China, Institute of Dermatology & Department of Dermatology at No. 1 Hospital, Anhui Medical University, the Key Laboratory of Gene Resource Utilization for Severe... Peng Huang, Jing Su, Hong-Bing Shen, Rong-Bin Yu, Zhi-Hang Peng, Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu Province, China. Department of Neurology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, 188 Shizi St, Suzhou 215006, China. Department of Urology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 332000, China. Department of Angrology, The Affiliated Hospital of Jiujiang College, Jiujiang, Jiangxi 332000, China. Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; State Key Laboratory of Pollution Control and Resource Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China Department of Stereotactic and Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; School of Materials Science and Hydrogen Energy, Foshan University, Foshan 528000, China; Guangdong Key Laboratory for Hydrogen Energy Technologies, Foshan University, Foshan 528000, China College of Materials Science and Engineering, Hunan Joint International Laboratory of Advanced Materials and Technology for Clean Energy, Hunan University, Changsha 410082, China Research Institute of Frontier Science Southwest Jiaotong University Chengdu 610031 P. R. China School of Pharmacy, Anhui University of Chinese Medicine Bioscience and Biotechnology Center, Nagoya University, 464-8601 Nagoya, Japan; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China Xiangya Hospital, Central South University, Changsha, China Laboratory of Molecular Imaging and Nanomedicine National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institutes of Health Bethesda MD 20892 USA State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Agriculture, Nanjing Agricultural University, Nanjing 210095, China Marshall Laboratory of Biomedical Engineering, International Cancer Center, Laboratory of Evolutionary Theranostics (LET), School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China |
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