http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_55f117cb378802eee1434154f7e33229
Outgoing Links
Predicate | Object |
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family-name | Hui Li Li |
name | Hui Li Hui. Li |
given-name | Hui. Hui |
organization-name | Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730000, Gansu, China. Department of Pathology, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China Department of Neurobiology, Beijing Key Laboratory of Neural Regeneration and Repair, Beijing Institute for Brain Disorders, Capital Medical University, 100069 Beijing, China; Center for Human Genome Research, Key Laboratory of Molecular Biophysics of the Ministry of Education College of Life Science and Technology Huazhong University of Science and Technology Wuhan P.R. China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012, People’s Republic of China Research Center of Integrative Medicine School Basic Medical Sciences Guangzhou University of Chinese Medicine Guangzhou China School of Materials Science and Engineering, Xiamen University of Technology, Xiamen 361024, China School of biological Science & Medical Engineering, Beihang University, Beijing, 100191, China Wuya College of Innovation Shenyang Pharmaceutical University Shenyang Liaoning P. R. China College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing, 211816, China Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium Center for Nanochemistry, Beijing National Laboratory for Molecular Sciences (BNLMS), State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, People’s Republic of China Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China Department of Cell Biology and Anatomy, Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA Viral Immunology Systems Program (VISP), The Kirby Institute University of New South Wales Sydney Australia College of Food Science and Pharmacy, Xinjiang Agricultural University, Urumqi 830052, China National Taiwan University Department of Thoracic Surgery Beijing Chao‐Yang Hospital Affiliated Capital Medical University Beijing China Department of Otorhinolaryngology Head and Neck Surgery, Peking University People’s Hospital, Beijing, People’s Republic of China Department of Pathology the First Affiliated Hospital Sun Yat‐Sen University Guangzhou China From the Institute for Translational Medicine and Therapeutics (H.L., D.J.R.), and Lipid Research Group, The Children’s Hospital of Philadelphia (P.D., E.T.A., M.C.P., S.L-K.), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. The University of Chicago, Department of Radiology, Chicago, Illinois Department of Nephrology, The First Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China Contribution from the Department of Chemistry, The University of Iowa, Iowa City, Iowa 52242, and Advanced Biomedical Computing Center, SAIC-Frederick, National Cancer Institute at Frederick, P.O. Box B, Frederick, Maryland 21702 Department of Pharmacology, School of Pharmacy Fudan University Shanghai China Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China. *Department of Dermatology, Key Laboratory for Liquid‐Solid Structural Evolution and Processing of Materials Ministry of Education School of Materials Science and Engineering Shandong University Jinan 250061 P. R. China Center for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan Key Laboratory of Reproduction and Genetics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan Provincial Obstetrical and Gynecological Diseases (Reproductive Medicine) Clinical Research Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan Engineering Laboratory of Preimplantation Genetic Diagnosis and Screening, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Faculty of Materials and Manufacturing, Beijing Key Lab of Microstructure and Properties of Advanced Materials, Beijing University of Technology, Beijing 100124, P. R. China Center for RNA Nanobiotechnology and Nanomedicine, College of Pharmacy, College of Medicine, Dorothy M. Davis Heart and Lung Research Institute, and James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, United States Department of Blood Transfusion, Chinese PLA General Hospital, Beijing, China. Weil Institute of Emergency and Critical Care Research, Virginia Commonwealth University, Richmond, Virginia Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing, School of Stomatology, Lanzhou University, Lanzhou 730030, China Department of Radiology The First Affiliated Hospital of Anhui Medical University Hefei China Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China College of Chemical Engineering Sichuan University Chengdu People's Republic of China Department of Respiratory Medicine, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, China Department of Chemical and Biomolecular Engineering, University of Houston, Houston, Texas 77204-4004, and Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204-5001 Department of Anesthesiology, Qingdao Municipal Hospital, Qingdao, Shandong 266011, P.R. China State Key Laboratory of Agrobiotechnology, College of Horticulture China Agricultural University Beijing China Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P.R. China Key Laboratory of Functional Molecular Solids; Ministry of Education; Anhui Key Laboratory of Chemo-Biosensing; College of Chemistry and Materials Science; Anhui Normal University Department of Pathology, First Affiliated Hospital; Sun Yat-Sen University; Guangzhou People's Republic of China Key Laboratory for Liquid−Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China State Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China Institute for Smart Materials & Engineering, University of Jinan, No. 336 Nanxinzhuang West Road, 250022 Jinan, P.R. China Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China Department of Chemistry National University of Singapore 3 Science Drive 3 117543 Singapore Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, People’s Republic of China The University of Chicago Department of Radiology Chicago Illinois USA State Key Laboratory of Biogeology and Environmental Geology Engineering Research Center of Nano-Geomaterials of Ministry of Education Faculty of Materials Science and Chemistry China University of Geosciences Wuhan 430074 P. R. China Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 200120, China Departments of Radiology, Biochemistry and Biophysics, Radiation Oncology, and Physics, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Chemistry, Shanghai University, Shanghai 200436, China; and Key Laboratory of Biomedical Photonics of Minister of Education, Huazhong University of Science and Technology, Wuhan 430074, China Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, East China University of Technology, Nanchang 330013, People’s Republic of China Key Laboratory of Chicken Genetics and Breeding of Agriculture Ministry, Key Laboratory of Animal Genetics, Breeding and Reproduction of Education Department of Heilongjiang Province, College of Animal Science and Technology, Northeast Agricultural University, Harbin, China Hubei Key Laboratory of Biomass Fibers and Eco‐dyeing and Finishing College of Chemistry and Chemical Engineering Wuhan Textile University Wuhan 430200 P. R. China Tianjin University College of Chemistry and Chemical Engineering Central South University Changsha Hunan 410083 China Beijing Key Laboratory of Microstructure and Properties of Advanced Material, Beijing University of Technology, 100, Pingleyuan, Chaoyang District, Beijing, 100124, China; Institute of Microstructure and Property of Advanced Materials, Beijing University of Technology, 100, Pingleyuan, Chaoyang District, Beijing, 100124, China State Key Laboratory of High Performance Ceramics and Superfine Microstructures Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co‐innovation Center of Neuroregeneration Nantong University Nantong PR China National‐Local Joint Engineering Laboratory of New Energy Photovoltaic Devices Key Laboratory of Digital Medical Engineering of Hebei Province College of Electron and Information Engineering Hebei University Baoding 071002 P. R. China State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, P. R. China Beijing FULLCAN Biotechnology Co. Ltd Beijing China Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China Department of Infectious Diseases and Clinical Microbiology Beijing Institute of Respiratory Medicine, Beijing Chao‐Yang Hospital, Capital Medical University Beijing Department of Chronic Diseases, Center for Disease Control and Prevention of Yangpu District, Shanghai 200090, China State Key Laboratory of Bioelectronics; Southeast University; Nanjing; People's Republic of China Institute of Pomology, Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China Authors' Affiliations: 1International Joint Cancer Institute, the Second Military Medical University; 2National Engineering Research Center for Antibody Medicine; 3State Key Laboratory of Antibody Medicine and Targeted Therapy; 4School of Medicine, Shanghai Jiao Tong University, Shanghai; and 5PLA General Hospital Cancer Center, PLA Postgraduate Medical School, Beijing, People's Republic of China Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Beijing 100020, China. Key Lab of Structures Dynamic Behavior and Control of the Ministry of Education (Harbin Institute of Technology) Harbin 150090 P. R. China; Center of Structural Health Monitoring and Control School of Civil Engineering Harbin Institute of Technology Harbin 150090 P. R. China Department of Pathology, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China Department of Medical Oncology, Ordos Central Hospital, Ordos, 017000, China Xiamen Key Laboratory of Marine Corrosion and Intelligent Protection Materials, Jimei University, Xiamen, 361021, China School of Chemical Engineering, Sichuan University, Chengdu, Sichuan, China School of Agricultural Engineering and Food Science Shandong University of Technology Zibo China Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China School of Marine Science and Technology, Northwestern Polytechnical University , Xi'an, Shaanxi 710072, China Department of Polymer Science, The University of Akron, Akron, Ohio 44325-3909, United States for the ATAMIS investigators Nanchang Center for Disease Control and Prevention Department of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China; Tongji Eye Institute, Tongji University School of Medicine, Shanghai, China Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China Department of Pharmacology Institute of Medical Sciences Shanghai Jiao Tong University School of Medicine Shanghai China The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing, China. Department of Cardiovascular Disease, The First Affiliated Hospital of Bengbu Medical College Department of Surgery and Anesthesia, The Third Affiliated Hospital of Sun Yatsen University Yuedong Hospital, Meizhou city, Guangdong Province, China. From the Acupuncture and Moxibustion Department (Y.Y., H.L., J.-W.Y., X.-R.W., G.-X.S., C.-Q.Y., S.-M.M., W.Z., Q.-Q.L., T.-R.L., C.-Z.L.) and Beijing Key Laboratory of Acupuncture Neuromodulation (X.-R.W.), Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, China; and Beijing University of Chinese Medicine, China (Y.Y., L.-Y.X.). Laboratory Animal Center and Department of Biochemistry Institute of Guangdong Engineering and Technology Research Center for Disease‐Model Animals Zhongshan School of Medicine Sun Yat‐sen University Guangzhou China Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RADX) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China iHuman Institute, ShanghaiTech University, Shanghai, China. Department of Pharmacology and Toxicology, The University of Arizona, Tucson, AZ Department of Anatomy Zunyi Medical University Zunyi China Department of Obstetrics and Gynaecology Laboratory for Corneal Tissue Engineering, College of Marine Life Sciences, Ocean University of China, Qingdao, Shandong 266100, China NMPA Key Laboratory for Technology Research and Evaluation of Drug Products Key Laboratory of Chemical Biology (Ministry of Education) Department of Pharmaceutics School of Pharmaceutical Sciences, Cheeloo College of Medicine Shandong University Jinan Shandong, 250012 China Institute of Theoretical and Computational Chemistry, Laboratory of Mesoscopic Chemistry, Department of Chemistry, Nanjing University, Nanjing, 210093, People’s Republic of China School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, People’s Republic of China. Northeast Normal University Institute of Functional Material Chemistry, Faculty of Chemistry, , Changchun 130024, People’s Republic of China Department of Clinical Pharmacology of Xiangya Hospital and Institute of Clinical Pharmacology Central South University Changsha 410078 China Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing, People’s Republic of China; Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, People’s Republic of China College of Food Science and Engineering, Ningxia University, Yinchuan 750021, China Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China College of Life Sciences and Shandong Engineering Research Center of Plant-Microbial Restoration for Saline-Alkali Land and State Key Laboratory of Crop Biology, Shandong Agricultural University, Tai’an, China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry; Jilin University; Changchun 130012; P. R. China Shanghai Key Lab of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200092, P. R. China Division of Respiratory Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, China Department of Pharmacy, Handan Central Hospital, Handan 056008, China Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Department of Pharmaceutics Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University Jinan Shandong Province 250012 P. R. China College of Chemical Engineering, Sichuan University, Chengdu, China Liquid‐Solid Structural Evolution & Processing of Materials (Ministry of Education) School of Materials Science and Engineering Shandong University Jinan Shandong 250061 China Univ Rennes, CNRS, ISCR-UMR 6226 35000 Rennes France Department of Gastrointestinal Cancer Biology, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin, P.R. China Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China Department of Neurology Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing, 210095, P.R. China.; Department of Medical Genetic and Cell Biology, Ningxia Medical University, Yinchuan, 750004, China. Tsinghua University Department of Pathology, Sir Run Run Shaw Hospital of Zhejiang University College of Medicine & Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou, China Department of Surgery, Division of Pediatric Surgery, Laboratory for Regenerative Tissue Repair, Texas Children’s Hospital and Baylor College of Medicine, Houston, TX, USA Institutes of Physical Science and Information Technology Anhui University Hefei 230601 P. R. China College of Agro-grassland Science, Nanjing Agricultural University, Nanjing, PR China Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, China School of Pharmacy, Guangxi Medical University, Nanning, Guangxi, China Department of Assisted Reproductive Centre, Zhuzhou Central Hospital, Xiangya Hospital Zhuzhou Central South University, Central South University, Zhuzhou, Hunan, China Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Jiangxi Key Laboratory of Organic Chemistry Jiangxi Science and Technology Normal University Nanchang People's Republic of China School of Public Health Southwest Medical University Luzhou Sichuan China Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, 29 Zhongguancun East Road, Haidian District, Beijing 100190, P. R. China Department of Chemistry Wake Forest University Winston‐Salem NC 27109 USA College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, People’s Republic of China Department of Pathology, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA Department of Anesthesiology The Second Xiangya Hospital Central South University Changsha China Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Chinese Academy of Medical Sciences, and Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, P.R. China Department of Ultrasound Shaanxi Provincial People's Hospital Xi'an China Department of Cell Biology and Anatomy, Chicago Medical School, 3333 Green Bay Road, North Chicago, Illinois 60064, USA College of Fisheries Henan Normal University Xinxiang China School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P. R. China Institute of Chinese Materia Medica; China Academy of Chinese Medical Sciences; Beijing 100700; China Department of Pediatrics, University of Texas Medical Branch at Galveston, Galveston, Texas, USA Department of Dermatology University of Alabama at Birmingham Birmingham AL Department of Chemistry; Wake Forest University; Winston-Salem; USA School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage; School of Chemistry and Chemical Engineering; Harbin Institute of Technology; Harbin 150001; People's Republic of China Department of Geology and Geophysics; Yale University; New Haven; USA The Research Centre of Anesthesiology and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Wuchang, Hubei Province, China East China Normal University Department of Stomatology, Aerospace Center Hospital, Beijing, China Key Laboratory for Liquid–Solid Structural Evolution and Processing of Materials; Ministry of Education; Shandong University; Jinan 250061; People's Republic of China Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802 School of Information Science and Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China Department of Pharmaceutics Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University Jinan 250012 P. R. China Inner Mongolia Key Laboratory of Chemistry and Physics of Rare Earth Materials, School of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China Beijing Institute of Basic Medical Sciences, Beijing, China. Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology , No. 8 Futong East Road, Chaoyang District, Beijing 100102 , China; Institute of Gene Science and Industrialization for Bamboo and Rattan Resources, International Centre for Bamboo and Rattan , No. 8 Futong East Road, Chaoyang District, Beijing 100102 , China Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China Center for Proteomics and Metabolomics, State Key Laboratory of Bio-Control, MOE Key Lab Aquatic Food Safety, School of Life Sciences, Sun Yat-sen University, University City, Guangzhou 510006, People’s Republic of China Institute of Clean Energy Chemistry, Key Laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials, College of Chemistry, Liaoning University, Shenyang 110036, China Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital and Institute, Beijing Beijing Key Laboratory of Environmental Science and Engineering, School of Chemical Engineering annd Environment, Beijing Institute of Technology, Beijing 100081, China Dep. of Crop and Soil Sciences Michigan State Univ. East Lansing MI 48824 Key Laboratory of Chicken Genetics and Breeding Ministry of Agriculture and Rural Affairs Harbin P.R. China; Key Laboratory of Animal Genetics, Breeding and Reproduction Education Department of Heilongjiang Province Harbin P.R. China; College of Animal Science and Technology Northeast Agricultural University Harbin P.R. China Jilin Cancer Hospital, Changchun 130012, China Department of Molecular PharmacologyStanford University School of MedicineStanfordCalifornia94305‐5332USA Peking University Sixth Hospital/Institute of Mental Health, China; National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Ministry of Health (Peking University), China Xiangya Nursing School, Central South University, Changsha, China Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science Beijing Institute of Technology Beijing China Nanoscience & Nanotechnology Initiative, Department of Physics, and Department of Chemistry, National University of Singapore, 2 Science Drive 3, 117542, Singapore Department of Biochemistry and Molecular Vascular Biology, Kanazawa University Graduate School of Medical Science, Kanazawa 920-8640, Japan Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China Co-Innovation Center for the Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, 210037, China; College of Forestry, Nanjing Forestry University, Nanjing, China Shanghai Key Laboratory of Chemical Biology, Center of Fluorine Chemical Technology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China for the CTS-AMI Investigators Triticeae Research Institute, Sichuan Agricultural University, Wenjiang, Chengdu, 611130, China Neurology-Neuroscience, University of Ottawa, Ottawa, Ontario, Canada Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, 600 Yishan Road, Shanghai 200233, China School of Resources and Civil Engineering, Northeastern University, Shenyang 110004, China Province Key Laboratory of Animal Resource and Epidemic Disease Prevention, School of Life Science, Liaoning University, Shenyang 110036, China Department of Medicine, Renal Electrolyte Division, and University of Waterloo 1 Department of Chemistry, , Waterloo, Ontario N2L 3G1, Canada From the University of Connecticut Health Center, Farmington, CT; The Cancer Institute of New Jersey; the Robert Wood Johnson Medical School, New Brunswick; and the University of Medicine and Dentistry of New Jersey School of Public Health, Piscataway, NJ. Beijing National Laboratory for Condensed Matter Physics and Institute of Physics; Chinese Academy of Sciences; Beijing 100190, China CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China Clean Nano Energy Center; State Key Laboratory of Metastable Materials Science and Technology; Yanshan University; Qinhuangdao 066004; P. R. China Central Laboratory of Xinjiang Medical University, Urumqi, Xinjiang 830011, P.R. China Institute of Cellular and Molecular Biology and Department of Molecular, Cellular, and Developmental Biology, University of Texas at Austin, Austin, TX 78712 Beijing Institute of Basic Medical Sciences, Beijing, China State Key Laboratory of Forest and Soil Ecology, Institute of Applied Ecology Chinese Academy of Sciences Shenyang China State Key Laboratory of Bio‐Control, Guangdong Key Laboratory of Pharmaceutical Functional Genes, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) Sun Yat‐sen University Guangzhou China; Laboratory for Marine Biology and Biotechnology and Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology Qingdao China Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School , Nanjing, Jiangsu , People’s Republic of China Department of Clinical Laboratory The Affiliated Hospital of Qingdao University Qingdao China Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, People's Republic of China; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, People's Republic of China; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, People's Republic of China Department of Medical Affairs, Jining No. 1 People's Hospital, Jining, Shandong 272011, P.R. China Department of Neurophysiology, The Second Affiliated Hospital of Qiqihar Medical College, Qiqihar, 161000, China Department of Pathology University of Iowa Carver College of Medicine Iowa City Iowa USA Clean Nano Energy Center State Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao 066004 China Department of Gynaecological Oncology, Sun Yat‐sen Memorial Hospital Sun Yat‐sen University Guangzhou China Beijing Institute of Basic Medical Sciences, Beijing 100850, China Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, P.R. China Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China Department of Pharmacology Peking University, Health Science Center Beijing China Clean Nano Energy Center, State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, China Renal-Electrolyte Division, Department of Medicine and; Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261 Department of Crop and Soil Sciences, and Environmental Science and Policy Program, Michigan State University, East Lansing, Michigan 48824, and Crop, Soil and Environmental Sciences, Lilly Hall of Life Sciences, Purdue University, West Lafayette, Indiana 47907 University of Nebraska-Lincoln Department of Chemistry, , Lincoln, Nebraska 68588, USA Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States Department of Pharmaceutics, Shenyang Pharmaceutical University Guangdong Provincial Center for Disease Control and Prevention, Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Panyu District, Guangzhou, China Authors' Affiliations: Divisions of 1Tumor Cell Biology and 2Comparative Medicine, Departments of 3Medical Oncology,4Pathology, and 5Information Science, 6Bioinformatics Core Facility, City of Hope Beckman Research Institute and Medical Center, Duarte, California; 7Department of Molecular Biology, 8Graduate School of Medicine, Sapporo Medical University, Sapporo, Japan; 9Department of Immunology & Biotherapy, Tianjin Cancer Hospital, Tianjin, China; and 10Incyte Corporation, Wilmington, Delaware Department of Physiology and Biophysical Sciences, State University of New York at Buffalo, Buffalo, NY 14214 1 Xiangya Hospital, Central South University Changsha China Department of Surgical Oncology, Xingtai People’s Hospital, No.16, Hongxing Street, Xingtai , 054031 , Hebei , China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry; Jilin University; Changchun 130012; China Guangdong Provincial Center for Disease Control and Prevention, Panyu District, Guangzhou, China Weil Institute of Emergency and Critical Care Research Virginia Commonwealth University Richmond VA Department of Orthopedics, the Second Xiangya Hospital of Central South University, Changsha - China School of Mechanical Engineering and Automation, Northeastern University, Shenyang 110819, China Jiangsu Engineering Technology Research Center of Meat Sheep & Goat Industry Nanjing Agricultural University Nanjing People's Republic of China; Jiangsu Livestock Embryo Engineering Laboratory Nanjing Agricultural University Nanjing People's Republic of China Department of Pediatrics Xi'an Jiaotong University First Hospital Xi'an PR China Key Laboratory of Cancer Prevention and Therapy, Department of Immunology, Tianjin Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China. Key Laboratory of Colloid and Interface Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, People’s Republic of China Department of Hepatobiliary Pancreatic Tumor Center, Chongqing University Cancer Hospital, Chongqing, 400030, China School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China College of Pharmaceutical Sciences, Southwest University Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, Peopleʼs Republic of China Department of Pathology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China School of Nursing Wenzhou Medical University Wenzhou China Department of Radiology University of Chicago Chicago Illinois State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, P. R. China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Orthopaedics TianjinNankai Hospital Tianjin China Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233000, P.R. China Department of Biotherapy State Key Laboratory of Biotherapy, West China Hospital Sichuan University Chengdu Sichuan China; West China Hospital, West China School of Medicine Sichuan University Chengdu Sichuan China State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology Chinese Academy of Sciences Beijing China Department of Abdominal Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, Fuzhou, Fujian, China Liver Cancer Institute and Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Fudan University, Ministry of Education, Shanghai, China Department of Orthopedics The Second Xiangya Hospital of Central South University Changsha Hunan China Department of Breast Surgery, Sichuan Cancer Hospital, Chengdu 610041, China Department of Anatomy, Guangzhou University of Chinese Medicine Department of Pathology, University of Washington, Seattle, Washington. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, People's Republic of China Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio‐X Center, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, China Beijing Key Laboratory of Environmental Science and Engineering, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, P.R. China Department of Chemistry, Nankai University, Tianjin 300071, China National Engineering Research Center for Advanced Polymer Processing Technology The Key Laboratory of Advanced Materials Processing & Mold of Ministry of Education Zhengzhou University Zhengzhou 450001 P. R. China Department of Gynecology and Obstetrics The First Affiliated Hospital of Harbin Medical University Harbin China Department of Epidemiology and Biostatistics,; Department of Pathology, and; Department of Gastrointestinal Surgery, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, People’s Republic of China; State Key Laboratory of Chemical Resource Engineering; Beijing University of Chemical Technology; Beijing 100029; China Maize Research Institute Sichuan Agricultural University ChengDu 611130 China College of Life Sciences Nanjing Agricultural University Nanjing China Ningbo Municipal Center for Disease Control and Prevention, China Department of Biochemistry and Molecular Biology, Beijing Institute of Basic Medical Sciences, Beijing, China. Department of Cardiology Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine (Luwan Branch) Shanghai China Beijing Chao‐Yang Hospital Capital Medical University Beijing China Department of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei Province, China. Department of Urology, Peking University International Hospital, Beijing 102206, P.R. China 4Laboratory of Biomedical Science, The Key Laboratory of Space Applied Physics and Chemistry Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology School of Science Northwestern Polytechnical University Xi'an 710072 P. R. China Peking University Sixth Hospital/Institute of Mental Health Beijing China; National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health Ministry of Health (Peking University Beijing China State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi University, Nanning 530005, China University of Science and Technology Beijing The First Department of Internal Medicine, Toyama Medical and Pharmaceutical University Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712 Institute of Pharmacy & Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hunan Provincial Key Laboratory of Tumor Microenvironment Responsive Drug Research, University of South China, Hengyang City, Hunan Province 421001, China State Key Laboratory for Conservation and Utilization of Subtropical Agro‐Bioresources Guangxi University Nanning China; School of Animal Science and Technology Guangxi University Nanning China National Center for Nanoscience and Technology, Beijing 100190, China Department of Medical Oncology, Ordos Central Hospital, Ordos 017000, China Department of Gastroenterology Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine Nanjing China College of Chemistry, Liaoning University, Shenyang 110036, P. R. China Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390;; Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390;; Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390; Department of Respiratory and Critical Care Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, P. R. China Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, Shandong 250061, P. R. China Department of Urology, Hebei Yanda Hospital, Langfang City 065201, Hebei Province, China Department of Dermatology Third Xiangya Hospital, Central South University Changsha China Department of Cardiology, Beijing Hospital, National Center of Gerontology, Dong Dan, Beijing, P.R. China School of Materials Science and Engineering, Hebei Provincial Key Laboratory of Traffic Engineering Materials, Shijiazhuang Tiedao University, Shijiazhuang 050043, China School of Computer and Communication Engineering, Zhengzhou University of Light Industry, Zhengzhou 450002, China Department of Pharmacology and Toxicology University of Arizona Tucson AZ 85721 USA Safety, Environment and Technology Supervision Research Institute of PetroChina Southwest Oil and Gas Field Company, Chengdu, China;; Sichuan Key Laboratory of Evaluation and Exploitation of Shale Gas, Chengdu, China; Department of Polymer Science; The University of Akron; Akron; USA State Key Laboratory of Precision Spectroscopy, East China Normal University, 200062 Shanghai, China; Division of Human Gene Therapy, Departments of Medicine, Pathology, and Surgery, and Gene Therapy Center, University of Alabama at Birmingham, Birmingham, AL 35294 Department of Neurology, The First Hospital of Jilin University, Changchun, China Department of Chemistry, University of Nebraska−Lincoln, Lincoln, Nebraska 68588, United States State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, People's Republic of China Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou 510006, People's Republic of China; National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou 510006, People's Republic of China Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm, College of Forestry and Landscape Architecture South China Agricultural University Guangzhou China Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors; Institute of Advanced Materials (IAM); Nanjing University of Posts & Telecommunications; Nanjing 210023; China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China Beijing National Laboratory for Molecular Sciences Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China The Univ. of Chicago University of Waterloo Department of Chemistry, , Waterloo, Ontario N2L 3G1, Canada College of Life Science, Liaoning University, Shenyang, 110036, China Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Sen. Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Department Of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Bengbu Medical College , Bengbu , Anhui 233000 , China Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, United States School of Chemical Engineering, Sichuan University, Chengdu, China; Department of Pathology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University The Kirby Institute, University of New South Wales, Australia Sydney NSW Australia College of Life and Environmental Science, Wenzhou University, Wenzhou, China College of Chemical Engineering; Sichuan University; Chengdu; China Department of Endocrinology Shaanxi Provincial People's Hospital Xi'an China From the Department of Clinical NeurosciencesUniversity of Calgary, Alberta, Canada. Beijing Key Laboratory of Environmental Science and Engineering, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada K1H 8M5 Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Shaanxi, Yangling 712100, China State Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry, Chinese Academy of Forestry, Beijing 100091, China *Department of Anesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Zhejiang 325027, China; and Key Laboratory of Plant Resources and Beijing Botanical Garden, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, Texas 78712, United States State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P.R. China School of Chinese Materia Medica Beijing University of Chinese Medicine Beijing China Ningbo Municipal Center for Disease Control and Prevention, Zhejiang Province, P R China Department of Radiology University of Chicago Chicago Illinois USA College of Life Sciences, Hunan Normal University, Changsha 410081, People’s Republic of China; Department of Cardiothoracic Surgery, ZhuJiang Hospital of Southern Medical University, Guangzhou, Guangdong, China Diabetes Center, Second Xiangya Hospital, and Institute of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University, Changsha, Hunan 410011, China. Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China; College of Forestry, Nanjing Forestry University, Nanjing 210037, China NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, PR China College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA School of Chemistry and Environmental Engineering; Wuhan Institute of Technology; Wuhan 430073; China Liver Cancer Institute Zhongshan Hospital Fudan University and Key Laboratory of Carcinogenesis and Cancer Invasion Ministry of Education Shanghai People's Republic of China Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi‑Organ Transplantation, Ministry of Public Health Key Laboratory of Organ Transplantation, Collaborative Innovation Center for Diagnosis Treatment of Infectious Diseases, Hangzhou, Zhejiang 310003, P.R. China State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Xinmin, Changchun, Jilin Province 130021, China Pfizer Global Research and Development, La Jolla Laboratories, 10777 Science Center Drive, San Diego, California 92121 Departments of Medicine and Cell Biology, University of Pittsburgh, Pittsburgh, PA 15261 Weil Institute of Emergency and Critical Care Research, Virginia Commonwealth University, Richmond, VA. Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, United States Department of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, Hebei Province, China Department of physics He Nan Normal University Xinxiang Henan 453007 China Department of Pharmacology and Molecular Toxicology University of Massachusetts Medical School Worcester, Massachusetts 01655-0126 Department of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing, China Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China Renal-Electrolyte Division, Department of Medicine and for the VICTORIA Study Group Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China Corresponding author. Institute of Endocrinology & Metabolism, The Second XiangYa Hospital of Central South University, Changsha, Hunan 410011, China State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210093, China Department of Chemical and Biomolecular Engineering, University of Notre Dame, 182 Fitzpatrick Hall, Notre Dame, Indiana 46556, United States Department of Cardiovascularology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China Department of Physics, Temple University, Philadelphia, Pennsylvania 19122, United States Department of Medical Oncology , Ordos Central Hospital , 017000 Ordos , Mongolia , China Department of Rehabilitation Medicine, Tianjin Medical University, Tianjin, China. The Water and Salt Research Center, and State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China Inflammation and Infection Research Centre, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia Center for Studies of Psychological Application and School of Psychology, South China Normal University , Guangzhou 510631 , China University of Nebraska-Lincoln Department of Chemistry, , Nebraska 68504, USA NMPA Key Laboratory for Technology Research and Evaluation of Drug Products Key Laboratory of Chemical Biology (Ministry of Education) Department of Pharmaceutics School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University Jinan 250012 P. R. China School of Life Sciences; Jilin University; Changchun 130012; China Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, P. R. China Department of Chemical and Biological Engineering, and ‡Energy Institute, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong; Department of Materials Science and Engineering, and ∥Department of Mechanical and Energy Engineering, South University of Science and Technology of China, 1088 Xueyuan Boulevard, Nanshan District, Shenzhen, Guangdong 518055, China State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210046, China College of Agronomy, Northwest A&F University/State Key Laboratory of Crop Stress Biology for Arid Areas , Yangling 712100, Shaanxi , China for the ARAIS Investigators Department of Hand and Foot Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China Key Laboratory of Water/Soil Toxic Pollutants Control and Bioremediation of Guangdong Higher Education Institutions, School of Environment, and ‡Department of Ecology, Jinan University, Guangzhou 510632, China Department of Ophthalmology, Shanghai Tenth People's Hospital, Shanghai, China; Devers Eye Institute, Legacy Research Institute, Portland, Oregon, United States MassGeneral Institute for Neurodegenerative Disease Department of Neurology, Massachusetts General Hospital Charlestown MA Liver Cancer Institute, Zhongshan Hospital,Fudan University and Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education,Shanghai,China Department of Neurology, The First Affiliated Hospital of Guangxi Medical University and Guangxi Key Laboratory of Precision Medicine in Cardio-Cerebrovascular Diseases Control and Prevention and Guangxi Clinical Research Center for Cardio-Cerebrovascular Diseases, Nanning, Guangxi, China (mainland) From the Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio-X Institute (Y.B., G.J., Yingchao Zhou, M.Z., Yuanyuan Zhao, S.L., F.W., Q. Lu, Y.H., Q.Y., T.K., H.L., X.R., C.X., X.T., Q.K.W.), and College of Life Science and Technology and Center for Human Genome Research, Institute of Cardiology (S.N., X.C., Y. Liao), Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Cardiology, Jining Medical College Affiliated... Department of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, Michigan 48824, United States Zhejiang University Department of Oral Surgery, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Center for Stomatology & National Clinical Research Center of Oral Disease, Shanghai, China; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China Department of Medical Affairs, Jining No.1 People’s Hospital, Jining, Shandong, China Department of Anesthesiology Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts & Telecommunications 9 Wenyuan Road Nanjing 210023 China College of Chemical Engineering Sichuan University Chengdu China Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104; Jiangxi Key Laboratory of Organic Chemistry Jiangxi Science and Technology Normal University Nanchang 330013 People's Republic of China Department of Respiratory Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu, People’s Republic of China Department of Endocrinology Shaanxi Provincial People's Hospital Xi'an City China National Institute of Biological Sciences, NIBS, Beijing, People's Republic of China School of Food and Biological Engineering Shaanxi University of Science and Technology Xi'an China Center for Proteomics, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, People’s Republic of China, School of Life Sciences, Guangxi University, Nanning 530004, People’s Republic of China, and Center for Proteomics, School of Life Sciences, Xiamen University, Xiamen 361005, People’s Republic of China Co-Innovation Center for Sustainable Forestry in Southern China, College of Forestry, Nanjing Forestry University, Nanjing 210037, China Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan The Institute for Advanced Studies, Wuhan University, Wuhan 430072, People’s Republic of China State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Xian Nong Tan Street 1, Xicheng District, Beijing 100050, China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jilin University Changchun 130012 P. R. China Department of Anesthesiology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China State Key Laboratory for Medical Genomics/Pôle Sino-Français de Recherche en Sciences du Vivant et Génomique, Ruijin Hospital Affiliated to Shanghai Second Medical University, 197 Rui Jin Road II, Shanghai 200025, China; Changchun University of Agriculture and Animal Sciences, Changchun 130062, China; Chinese National Human Genome Center, 250 Bi Bo Road, Zhang Jiang High Tech Park, Shanghai 201203, China; Guangdong Center for Disease Control and Prevention, 176 Xingangxi Road, Guangzhou 510300,... Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, PR China Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637; Department of Medical Oncology, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China The Third Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou China College of Agronomy Sichuan Agricultural University Chengdu 611130 China Department of Oncology Affiliated Hospital of Jining Medical University Jining China Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin University, Changchun 130021, China Institute of Life and Health Engineering/National Engineering Research Center of Genetic Medicine, Jinan University, Guangzhou, People's Republic of China. Department of Cardiology, The Second Affiliated Hospital of Soochow University , Suzhou , China Institute of Dermatology and Department of Dermatology at No. 1 Hospital Anhui Medical University Hefei China; Key Laboratory of Dermatology Anhui Medical University Ministry of Education Hefei China Key Laboratory of Intelligent Information Processing, Advanced Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China School of Biological Science and Technology University of Jinan Jinan 250022 China Neurology, and Key Laboratory of Chicken Genetics and Breeding Ministry of Agriculture Harbin China; Key Laboratory of Animal Genetics, Breeding and Reproduction Education Department of Heilongjiang Province Harbin China; College of Animal Science and Technology Northeast Agricultural University Harbin China The Second Xiangya Hospital of Central South University, Changsha, China China National GeneBank, Beijing Genomics Institute (BGI)–Shenzhen, Shenzhen, 518083, China. Yunnan Provincial Engineering and Research Center for Sustainable Utilization of Honeybee Resources, Eastern Bee Research Institute, College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China College of Chemical Engineering, Sichuan University, Chengdu 610065, Sichuan, China State Key Laboratory of Efficient Development of Offshore Oil, Beijing 100028, China; Bohai Petroleum Research Institute, Tianjin Branch of CNOOC (China) Co., Ltd., Tanggu, Tianjin 300450, China Department of Immunology and Microbiology, Medical School of Jishou University, Jishou, Hunan 416000, P.R. China Key Laboratory of Water/Soil Toxic Pollutants Control and Bioremediation of Guangdong Higher Education Institutions, School of Environment, Jinan University, Guangzhou 510632, China Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine , College of Veterinary Medicine , Northeast Agricultural University , Harbin 150030 , China Tea Science Research Institute, College of Horticulture, Nanjing Agricultural University, Nanjing, 210095, People’s Republic of China Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine Shanghai People's Republic of China State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China Department of Internal Medicine and Animal Reproduction Institute, State Key Laboratory for Conservation and Utilization of Subtropical Agro‐bioresources Guangxi University Nanning China Centre for Bioengineering and Biotechnology, China University of Petroleum (East China), 66 Changjiang West Road, Qingdao 266580, People’s Republic of China Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, Guangdong, China College of Chemistry and Key Laboratory of Polymeric Materials & Application Technology of Hunan Province, Xiangtan University, Xiangtan 411105, PR China, State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, PR China Department of Chemistry, Shanghai Normal University, Shanghai 200234, China, and Chemical and Biomolecular Engineering Department, University of California, Los Angeles, California 90095 Department of Hepatobiliary Surgery, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China State Key Laboratory of Applied Organic Chemistry; College of Chemistry and Chemical Engineering; Lanzhou University; Lanzhou 730000; China State Key Laboratory of Urban Water Resource and Environment (SKLUWRE), School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China Institute of Quality Standard and Testing Technology for Agro-Products, Key Laboratory of Agro-Product Quality and Safety, Chinese Academy of Agricultural Sciences; Key Laboratory of Agro-Product Quality and Safety, Ministry of Agriculture, Beijing 100081, P.R. China for the TESTING Study Group State Key Laboratory of Reproductive Medicine Nanjing Medical University Nanjing 211166 P. R. China Institute of Microstructure and Property of Advanced Materials Beijing Key Lab of Microstructure and Property of Advanced Materials Beijing University of Technology Beijing 100124 China Center for Proteomics and Metabolomics, State Key Laboratory of Biocontrol, School of Life Sciences, MOE Key Lab Aquat Food Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, People’s Republic of China Key Laboratory of Pediatric Hematology and OncologyMinistry of HealthShanghai Jiao Tong University School of Medicine Shanghai China; Pediatric Translational Medicine InstituteShanghai Children's Medical CenterShanghai Jiao Tong University School of Medicine Shanghai China; Department of Pharmacology and Chemical BiologySchool of Basic MedicineShanghai Jiao Tong University School of Medicine Shanghai China; Collaborative Innovation Center for Translational MedicineShanghai Jiao Tong University School of Medicine Shanghai China Department of Internal Medicine, College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA Department of Chemistry and Nebraska Center for Materials and Nanoscience, University of Nebraska-Lincoln, Lincoln, Nebraska 68588 Department of Orthopedics, The Second Xiangya Hospital of Central South University , Changsha , China Department of Medical Oncology, Ordos Central Hospital, Ordos, P.R. China Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin 300052, PR China Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, China. Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA State Key Laboratory of Inorganic Synthesis and Preparative Chemistry Jilin University Changchun 130012 China Clean Nano Energy Center, State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, P. R. China Cardiovascular Institute and Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China Key Laboratory of Chicken Genetics and Breeding; Ministry of Agriculture; Key Laboratory of Animal Genetics, Breeding and Reproduction; Education Department of Heilongjiang Province; College of Animal Science and Technology; Northeast Agricultural University; Harbin Heilongjiang 150030 China Department of Optoelectronic Science and Engineering; College of Science; Donghua University; Shanghai 201620; China State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, P. R. China, and Institute of Theoretical and Computational Chemistry, Key Laboratory of Mesoscopic Chemistry of MOE, Nanjing University, Nanjing 210093, P.R. China Beijing National Laboratory for Condensed Matter Physics, and Institute of Physics, Chinese Academy of Sciences, Beijing, 100190, P. R. China; Collaborative Innovation Center of Quantum Matter, Beijing 100190, China National Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology The Innovative Academy for Seed Design, Chinese Academy of Sciences Beijing 100101 China; University of Chinese Academy of Sciences Beijing 100039 China Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Departments of Biology and Biochemistry, Chemistry, and Chemical Engineering, University of Houston, Houston, Texas 77204-5513 Breast Cancer Center, East Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Tongji University, Shanghai 200120, People’s Republic of China Department of Colorectal Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, P. R. China Key Laboratory of Low Carbon Culture and Safety Production in Cattle in Sichuan, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China Department of Pulmonary and Critical Care Medicine, Beijing Anzhen Hospital Capital Medical University Beijing China; Beijing Institute of Heart, Lung and Blood Vessel Diseases Beijing China Institute of Nano Biomedicine and Engineering, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, PR China College of Chemical Engineering Sichuan University Chengdu 610065 People's Republic of China School of Thermal Engineering, Shandong Jianzhu University, Jinan 250101, China Clean Nano Energy Center State Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao 066004 P. R. China Shenzhen Technology University, Shenzhen 518118, People’s Republic of China Center for Reproductive Medicine The First Affiliated Hospital of Zhengzhou University Zhengzhou China; Henan Key Laboratory of Reproduction and Genetics The First Affiliated Hospital of Zhengzhou University Zhengzhou China; Henan Provincial Obstetrical and Gynecological Diseases (Reproductive Medicine) Clinical Research Center The First Affiliated Hospital of Zhengzhou University Zhengzhou China Joint National Laboratory for Antibody Drug Engineering, The First Affiliated Hospital, School of Basic Medicine Henan University Kaifeng China Hunan Academy of Forestry, Changsha 410000, Hunan, P. R. China School of Public Health, Anhui Medical University, Hefei, China Division of Respiratory Medicine, the Affiliated Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, People's Republic of China Laboratory of Pharmaceutical Engineering School of Life Science and Health Engineering Jiangnan University Wuxi China Department of Dermatology Institute of Dermatology The First Affiliated Hospital Anhui Medical University Hefei Anhui People's Republic of China State Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China. Collaborative Innovation Center for Marine Biomass Fibers Materials and Textiles of Shandong Province School of Environmental Science and Engineering Qingdao University Qingdao 266071 P. R. China Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, PR China Department of Breast Surgery II, BaoTou Tumor Hospital, Baotou, China Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China School of Kinesiology, Shanghai University of Sport, Shanghai 200438, P.R. China Department of Oncology, The Fourth Medical Center of PLA General Hospital College of Landscape Architecture and Life Science, Chongqing University of Arts and Sciences, Chongqing 402160, China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha, Hunan 410082, P. R. China Center for Studies of Psychological Application and School of Psychology, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province South China Normal University Guangzhou China Department of Pharmacology & Nutritional Sciences University of Kentucky College of Medicine Lexington Kentucky National Clinical Research Center of Cancer Tianjin China; Key Laboratory of Cancer Immunology and Biotherapy Tianjin China; Department of Immunology Tianjin Medical University Cancer Institute and Hospital Tianjin China Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Beijing 100700, China Department of Anesthesiology The Second Xiangya Hospital, Central South University Changsha City China; Department of Anatomy and Neurobiology, School of Basic Medical Science Central South University Changsha City China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials; Ministry of Education; Shandong University; Jinan; People's Republic of China Anhui Provincial Laboratory of Local Livestock and Poultry Genetical Resource Conservation and Breeding, College of Animal Science and Technology Anhui Agricultural University Hefei Anhui province China School of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China. Department of Chemistry and Biochemistry, University of Bern, CH-3012 Bern, Switzerland Department of Polymer Science The University of Akron Akron OH 44325-3909 USA The State Key Laboratory of Medical Genetics and School of Life Sciences Central South University Changsha China Qiqihaer Medical University, Qiqihaer, China State Key Laboratory of Vegetable Biobreeding, Beijing Vegetable Research Center, Beijing Academy of Agriculture and Forestry Science, Beijing 100097, China; National Engineering Research Center for Vegetables, Beijing Vegetable Research Center, Beijing Academy of Agriculture and Forestry Science, Beijing 100097, China; Beijing Key Laboratory of Vegetable Germplasms Improvement, Beijing 100097, China; Key Laboratory of Biology and Genetics Improvement of Horticultural Crops (North China), Beijing 100097, China School of Textile Science and Engineering, Tiangong University, Tianjin, 300387, China National-Local Joint Engineering Laboratory of New Energy Photovoltaic Devices, Machine Vision Engineering Technology Center of Hebei Province, Key Laboratory of Digital Medical Engineering of Hebei Province, College of Electron and Information Engineering, Hebei University, Baoding 071002, P. R. China Department of Ophthalmology, The Affiliated Hospital of Qingdao University Qingdao, Qingdao, China From the Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China (Y.Y., W.-L.B., S.-l. Zhang, H.-D.L., H.L., W.-Z.D., X.-Y.C., X.W., L.-X.L., X.S.) College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University Wuhan 430072 P. R. China Department of Thoracic Surgery, Beijing Chaoyang Hospital Capital Medical University Beijing China Thoracic Oncology Program, Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA Institute of Endocrinology and Metabolism, Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China Department of Head and Neck Surgery, Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center of Cancer Medicine Guangzhou Guangdong China Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China Breast Cancer Center East Hospital Affiliated to Tongji University Tongji University School of Medicine Shanghai Key Laboratory of Chemical Assessment and Sustainability School of Chemical Science and Engineering Tongji University Shanghai 200120 P. R. China Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, People’s Republic of China Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China Department of Joint Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, China CAS Key Laboratory of Soft Matter Chemistry; iChEM (Collaborative Innovation Center of Chemistry for Energy Materials); Department of Polymer Science and Engineering; University of Science and Technology of China; Hefei State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, P. R. China Department of Hematology, Qilu Hospital, and College of Nursing, University of Utah, Salt Lake City, UT, USA Key Laboratory of Plant Resources and Beijing Botanical Garden Institute of Botany, Chinese Academy of Sciences Xiangshan Beijing 100093 China Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; National Clinical Research Center of Cancer, Tianjin, China; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China University of Maryland School of Medicine Yunnan Green Field Biological Pharmaceutical Co., Ltd., Kunming, China State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Beijing 100029 P. R. China The University of Chicago, Department of Radiology, Chicago, Illinois, United States State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Sir Y.K. Pao Cancer Center, Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong SAR PR China Nanjing Glomerulonephritis Registry, National Clinical Research Center for Kidney Diseases, Jinling Hospital, Nanjing 210000, China Section of Molecular Cell & Developmental Biology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712 College of Chemistry and Chemical Engineering, North Minzu University, Yinchuan, Ningxia 750021, P. R. China Jilin Key Laboratory of Solid-State Laser Technology and Application, School of Physics, Changchun University of Science and Technology, Changchun 130022, China The Key Laboratory of Space Applied Physics and Chemistry; Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology; School of Science; Northwestern Polytechnical University; Xi'an College of Fundamental Medical Science, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences Fudan University Shanghai China State Key Laboratory of Analytical Chemistry for Life Science; School of Chemistry and Chemical Engineering; Nanjing University; China State Key Laboratory of Polymer Physics and Chemistry; Institute of Applied Chemistry; Chinese Academy of Sciences; Changchun 130022, P. R. China School of Environmental and Chemical Engineering; Shanghai University; Shanghai 200444; China State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Animal Science and Technology, Guangxi University, Nanning 530004, China Department of Biochemistry and Molecular Biology Harbin Medical University Harbin Heilongjiang 150081 People's Republic of China Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College Kunming China State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection Chinese Academy of Agricultural Sciences Beijing China University of Alabama at Birmingham, Birmingham, AL 35294 1 Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China; Department of Pathogen Biology, School of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Center for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Sun Yat-sen University, University City, Guangzhou 510006, People’s Republic of China, and School of Life Sciences, Xiamen University, Xiamen 361005, People’s Republic of China CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and Engineering University of Science and Technology of China Hefei Anhui 230026 P. R. China School of Science, RMIT University, Melbourne, Victoria 3000, Australia School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, China Department of Microbiology and Immunology, Medical School of Jishou University, Jishou, Hunan 416000, P.R. China Shanghai Engineering Research Center of Food Microbiology, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China Departments of Pharmacology and Molecular Toxicology and Cell Biology, Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655 State Key Laboratory of Forest and Soil Ecology Institute of Applied Ecology Chinese Academy of Sciences Shenyang 110016 China Department of Ultrasound, Xinqiao Hospital, Army Medical University, Chongqing, China Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland Department of Molecular Biology, Princeton University, Princeton, NJ 08544 Clinical College, Jilin University, Changchun Guangdong Center for Disease Control and Prevention, Guangzhou, Guangdong, People's Republic of China Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha 410008, China; Hunan Key Laboratory of Joint Degeneration and Injury, Changsha 410008, China School of Life Sciences and Biotechnology (H.L., Z.Y., W.L., J.Z., D.Z.) and State Key Laboratory of Hybrid Rice (Z.Y., D.Z.), Shanghai Jiao Tong University, Shanghai 200240, China; Plant Sciences Division, School of Biosciences, University of Nottingham, Loughborough, Leicstershire LE12 5RD, United Kingdom (Z.Y., G.V.-B., C.Y., Z.A.W.) grid.258151.a 0000000107081323 School of Pharmaceutical Science Jiangnan University 1800 Lihu Avenue 214122 Wuxi People’s Republic of China Ocean University of China Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement, Institute of Pomology, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China The Center for Human Genome Research, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan (C.F., P.W., D.Y., X.Z., D.G.,L.L., X.B., W.X., H.L., Y.Y., X.R., T.K., X.T., C.X., Q.K.W.). Max-Planck-Institut für Quantenoptik 1 , Hans-Kopfermann-Str. 1, D-85748 Garching, Germany; Ludwig-Maximilians-Universität München 2 Department of Physics, , Am Coulombwall 1, D-85748 Garching, Germany Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital,Zhejiang University,Hangzhou,China; National Health and Family Planning Commission of China Key Laboratory of Combined Multi-Organ Transplantation,Hangzhou,China; Key Laboratory of the Diagnosis and Treatment of Organ Transplantation,CAMS,Hangzhou,China; Key Laboratory of Organ Transplantation,Hangzhou,China; Collaborative Innovation Center for Diagnosis Treatment of Infectious Disease,Hangzhou,China Trauma Center/Department of Emergency and Traumatic Surgery, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China Key Laboratory of Food Nutrition and Safety of SDNU, Provincial Key Laboratory of Animal Resistant Biology, College of Life Science, Shandong Normal University, Jinan 250014, China Faculty of Materials and Manufacturing Beijing Key Lab of Microstructure and Properties of Advanced Materials Beijing University of Technology Beijing 100124 P. R. China Department of Polymer Science, The University of Akron, Akron, Ohio 44325, United States Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Sichuan Agricultural University, Chengdu 611130, China; Triticeae Research Institute, Sichuan Agricultural University, Chengdu 611130, China Department of Human Sperm Bank, West China Second University Hospital of Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China. College of Chemistry; Key Laboratory of Advanced Energy Materials Chemistry (MOE); Tianjin Key Laboratory of Metal and Molecule Based Material Chemistry; Collaborative Innovation Center of Chemical Science and Engineering; Nankai University College of Chemistry and Pharmaceutical Sciences; Qingdao Agricultural University; Qingdao; People's Republic of China Department of Taian, The 960 Hospital of the PLA, Taian, Shandong, China Department of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin, Helongjiang, China Shanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology Shanghai Public Security Bureau Shanghai P. R. China Key Laboratory of Colloid and Interface Chemistry Ministry of Education School of Chemistry and Chemical Engineering Shandong University Jinan 250100 P. R. China State Key Laboratory of Natural Medicines Jiangsu Key Laboratory of Carcinogenesis and Intervention Key Laboratory of Drug Quality Control and Pharmacovigilance Ministry of Education Jiangsu Key Laboratory of Drug Design and Optimization China Pharmaceutical University China Pharmaceutical University Nanjing Jiangsu China Department of New Drug Evaluation Beijing Institute of Pharmacology and Toxicology Beijing China Department of Cardiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, P.R. China Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu 610064, P. R. China Cancer Center, The Burnham Institute, La Jolla, California Department of Chemistry Dartmouth College Hanover NH 03755 USA College of Materials and Energy, South China Agricultural University, Guangzhou 510642, China College of Materials and Energy; South China Agricultural University; Guangzhou 510642; China College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao 266580, Shandong, China Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, China Department of Breast Surgery, the Second People’s Hospital of Sichuan Province Key Laboratory of Radiopharmacokinetics for Innovative Drugs Chinese Academy of Medical Sciences, and Institute of Radiation Medicine Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin 300192 P. R. China Beijing National Laboratory for Molecular Science (BNLMS); Institute of Chemistry; Chinese Academy of Science; Beijing 100190, P. R. China; Graduate University of Chinese Academy of Sciences (GUCAS) Department of Chemical Biology and ‡Department of Medicinal Chemistry, School of Pharmaceutical Sciences, The State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China Beijing National Laboratory for Molecular Sciences CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Department of Pathology, Shanghai Medical College, Fudan University Shanghai 200032, China. Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China Department of Materials Science and Engineering, Northwestern University, 2220 Campus Drive, Evanston, Illinois 60208, United States Dep. of Plant, Soil and Microbial Sciences; Michigan State Univ.; East Lansing MI 48824 State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, China School of Chemistry and Chemical Engineering Central South University Changsha China School of Materials Science and Engineering, Beijing University of Technology, Beijing 100124, People’s Republic of China KLMME, Institute of Evolution and Marine Biodiversity, Ocean University of China , Qingdao, Shandong Province 266003 , China Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China Department of Dermatology, Hospital of Weifang People Department of Liver Surgery & Transplantation, Liver Cancer Institute & Zhongshan Hospital, Fudan University, Shanghai, 200032, China; Key Laboratory of Carcinogenesis & Cancer Invasion (Fudan University), Ministry of Education, Fudan University, Shanghai, 200032, China University of Alabama at Birmingham, Birmingham, Alabama, United States Shenzhen Key Laboratory of Marine Bioresources and Ecology; Guangdong Provincial Key Laboratory for Plant Epigenetics; College of Life Sciences and Oceanography; Shenzhen University; Shenzhen 518055 China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China. State Key Laboratory of Applied Organic Chemistry & Department of Chemistry, Lanzhou University, Lanzhou 730000, P.R. China College of Sport Human Sciences, Harbin Sport University, Harbin, China School of Chemistry and Chemical Engineering, North Minzu University, Yinchuan 750021, China; Key Laboratory for Chemical Engineering and Technology, State Ethnic Affairs Commission, Yinchuan 750021, China Department of Bone and Joint Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China Department of Neurosurgery the First Affiliated Hospital of Chongqing Medical University Chongqing China Beijing Key Laboratory of Environmental Science and Engineering, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, PR China Beijing Center for Disease Prevention and Control, Beijing 100013, China. Key Laboratory of Rubber-Plastics, Ministry of Education/Shandong Provincial Key Laboratory of Rubber Plastics, Qingdao University of Science & Technology, Qingdao 266042, China Department of Internal Medicine‐Oncology Inner Mongolia Autonomous Region People's Hospital Hohhot P.R. China CAS Key Laboratory of Soft Matter Chemistry; Department of Polymer Science and Engineering; University of Science and Technology of China; Hefei; China Department of Anatomy and Neurobiology Northeast Ohio Medical University Rootstown OH USA Faculty of Psychology Beijing Normal University China From the Departments of Medicine (A.M.P., D.W.N., O.M.K., W.L., H.L., F.Y.S., M.A.J., W.K., R.M.W., C.D.S., M.E.A., K.G.L., I.M.G.), Molecular Physiology and Biophysics (C.D.S., M.E.A.), and Pharmacology (P.K., C.D.S., K.G.L.), University of Iowa Carver College of Medicine, Iowa City, IA; and Iowa City VA Healthcare System, Iowa City, IA (K.G.L., I.M.G.). Department of Infectious Disease Pfizer Global Research and Development, La Jolla Laboratories, 10724 Science Center Drive, San Diego, California 92121 Department of Materials Science and Engineering, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Peking University , Beijing , China College of Agriculture Northeast Agricultural University Harbin Heilongjiang China Department of Natural Products for Chemical Genetic Research, Key Laboratory of Brain Functional Genomics, Ministry of Education & Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, No. 3663 Zhongshan Road N, Shanghai 200062, People’s Republic of China, Institute of Biomedical Sciences, School of Life Science, East China Normal University, No. 500 Dongchuan Road, Shanghai 200240, People’s Republic of China, and Lab of Plant Health and Natural Product & Key Laboratory of... Shanghai Key Laboratory of Crime Scene Evidence; Shanghai Research Institute of Criminal Science and Technology; Shanghai 200083; China Key Laboratory for Advanced Materials, Center for Computational Chemistry and Research Institute of Industrial Catalysis, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China Department of Obstetrics and Gynecology, Center of Gynecologic Oncology Peking University People's Hospital Beijing China Departments of 1Medicine, College of Pharmacy, Dalian Medical University, Dalian 116044, China Department of Pathology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, Collaborative Innovation Center for Coal Based Energy (i-CCE), East China University of Science and Technology, Shanghai 200237, P. R. China University of Chicago, Department of Radiology, Chicago, Illinois State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China Hematology Department of Radiology, Department of Biochemistry and Biophysics, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104; and Department of Chemistry, Shanghai University, Shanghai 200436, China; and Department of Pediatric GI Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA 19104 Department of Endocrinology and Metabolism Tianjin Medical University General Hospital Tianjin China GanSu Provincial Center for Disease Control and Prevention, Lanzhou, China Department of Food Science and Engineering, School of Chemistry and Chemical Engineering Harbin Institute of Technology 73 Huanghe Road Harbin 150090 China State Key Laboratory of Pharmaceutical Biotechnology School of Life Sciences Nanjing University Nanjing 210023 P. R. China Departments of aMedicine and School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi 214122, China Guangdong Provincial Center for Disease Control and Prevention Guangdong Workstation for Emerging Infectious Disease Control and Prevention Guangzhou China Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing 100081, China Key Laboratory of Radiopharmacokinetics for Innovative Drugs Chinese Academy of Medical Sciences Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine Chinese Academy of Medical Sciences & Peking Union Medical College Tianjin 300192 P. R. China State Key Laboratory of Reproductive Medicine, Nanjing Medical University, 211166 Nanjing, People’s Republic of China; Key Laboratory of Pediatric Hematology and Oncology Ministry of Health, Department of Hematology and Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Pediatric Translational Medicine Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Pharmacology and Chemical Biology, School of Basic Medicine and Collaborative Innovation Center for Translational Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China Department of Chemical Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of Korea Beijing Key Lab of Microstructure and Properties of Advanced Materials Beijing University of Technology Beijing 100124 P. R. China Department of Pathology, Bethune International Peace Hospital, Shijiazhuang, Hebei 050082, P.R. China Department of Orthopedics, The Second Xiangya Hospital of Central South University, Changsha, China Department of Plant Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, People's Republic of China Department of Internal Medicine, College of Medicine, East Tennessee State University, Johnson City Department of Oncology, Nanjing Jinling Hospital of Nanjing University, Nanjing, Jiangsu 210002, P.R. China Key Laboratory of Health Ministry for Congenital Malformation Shengjing Hospital China Medical University Shenyang China Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, P.R. China College of Forestry, Nanjing Forestry University, Nanjing 210037, China; Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing 210037, China State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai’an, Shandong 271018, China College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China Shanghai Qeejen Bio-tech Institution, Shanghai, China Key Laboratory of Material Physics, Ministry of Education, School of Physics and Microelectronics, Zhengzhou University, Zhengzhou 450052, P. R. China Guangdong Provincial Center for Disease Control and Prevention, No. 160, Qunxian Road, Panyu District, Guangzhou, China State Key Laboratory of Microbial Metabolism & Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Key Laboratory of Chicken Genetics and Breeding Ministry of Agriculture and Rural Affairs Harbin China; Key Laboratory of Animal Genetics, Breeding and Reproduction Education Department of Heilongjiang Province Harbin China; College of Animal Science and Technology Northeast Agricultural University Harbin China Department of Chemistry; Collaborative Innovation Center of Chemical Science and Engineering; Nankai University; and Key Laboratory of Advanced Energy Materials Chemistry (MOE); Tianjin 300071 The School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China Beijing Key Laboratory for Optical Materials and Photonic Devices (BKLOMPD), Department of Chemistry, Capital Normal University, Beijing 100048, People’s Republic of China University of Chicago, Department of Radiology, 5841 South Maryland Avenue, MC 2026, Chicago, Illinois 60637, United States College of Chemistry and Molecular Science Wuhan University Wuhan 430072 China Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM) School of Physical and Mathematical Sciences Nanjing Tech University (NanjingTech) Nanjing 211816 China Department of Chemistry, University of Chicago, Chicago, IL 60637, USA. Institutes of Physical Science and Information Technology Anhui University Hefei 230601 China Department of Radiation Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou 350014, China Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, College of Life Sciences South China Normal University Guangzhou China 510631 Shaanxi Key Laboratory of Agricultural Molecular Biology, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China State Key Laboratory of Developmental Biology of Freshwater Fish, Hunan Provincial Key Laboratory of Microbial Molecular Biology, College of Life Science Hunan Normal University Changsha China State Key Laboratory of Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu China; National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu China; National Engineering Laboratory for Oral Regenerative Medicine West China Hospital of Stomatology Sichuan University Chengdu China Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing, China Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510 State Key Laboratory of Metal Matrix Composites; School of Materials Science and Engineering; Shanghai Jiao Tong University; Shanghai; China Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, Connecticut 06492 Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China, and State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China 1The First Affiliated Hospital; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases; Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, P.R. China. Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, China Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410013, Hunan, China National Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai 201306, China Department of General Medicine Dongfang Hospital Beijing University of Chinese Medicine (Western Section) Beijing China School of Environment, Beijing Normal University, Beijing 100875, China State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, P. R. China Basic Medicine Hebei Medical University Shijiazhuang Hebei People's Republic of China Departement für Chemie und Biochemie, Universität Bern, Freiestrasse 3, CH-3012 Bern, Switzerland, and College of Chemistry, Xiangtan University, Xiangtan 411105, P.R. China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Department of Chemistry Jilin University Changchun 130012 China Department of Ultrasound The Second Affiliated Hospital of Army Medical University Chongqing China College of Chemistry, Jilin University, Changchun 130012, People’s Republic of China Key Laboratory for Liquid−Solid Structural Evolution and Processing of Materials, Ministry of Education, Shandong University, Jinan 250061, People’s Republic of China Department of Cardiology, First Affiliated Hospital of Soochow University, Suzhou, China Department of Pharmacology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine , Hefei , China Key Laboratory of Animal Genetics, Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, College of Animal Science, Guizhou University, Guiyang 550025, China Key Laboratory of Bio-based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China Cancer Center and Department of Medicine, and Ireland Cancer Center, Department of Medicine, and Research Institute, University Hospitals of Cleveland and Case Western Reserve University, Cleveland, OH 44106; Departments of Molecular Biology and Microbiology, and Physiology and Biophysics, and Department of Pathology and Cancer Center, Case Western Reserve University, Cleveland, OH 44106; Division of Human Cancer Genetics, Ohio State University, Columbus, OH 43210; Howard Hughes Medical... National Glycoengineering Research Center, School of Pharmaceutical Science, Shandong University, Jinan, China Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco‐Environment and Bio‐Resource of the Three Gorges Area, Key Laboratory of Eco‐environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Southwest University Chongqing China School of Kinesiology, Shanghai University of Sport, Shanghai, China Jilin Ginseng Academy Changchun University of Chinese Medicine Changchun China Department of Hepatology The Second People's Hospital of Yunnan Province Kunming China Center for Nanochemistry, Beijing National Laboratory for Molecular Sciences (BNLMS), State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China Institute of Ultrafast Optical Physics Department of Applied Physics and MIIT Key Laboratory of Semiconductor Microstructure and Quantum Sensing Nanjing University of Science and Technology Nanjing 210094 P. R. China Department of Chemistry and Biochemistry, North Dakota State University, Fargo, North Dakota 58108, United States Department of Oncology, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia 010017, P.R. China Department of Pathology Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai People's Republic of China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012, P. R. China Hubei Key Lab of Electrochemical Power Sources, College of Chemistry & Molecular Science, Wuhan University, Wuhan 430072, China Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China Department of Chemistry, Teachers College of Qingdao University, Qingdao, Shandong 266071, China Renal-Electrolyte Division and Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA. From the Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, National Clinical Research Center for Respiratory Diseases (B.C., Yeming Wang, G.F., F.Z., X.G., Z.L., Y.Z., Hui Li, L.S., C.W.), and the Institute of Clinical Medical Sciences (G.F., X.G.), China–Japan Friendship Hospital, the Institute of Respiratory Medicine, Chinese Academy of Medical Sciences (B.C., Yeming Wang, F.Z., Z.L., Y.Z., Hui Li, C.W.), the Clinical and Research Center of Infectious Diseases, Beijing... Department of Gastrointestinal Cancer Biology, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China College of Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (MOE), Tianjin Key Laboratory of Metal and Molecule Based Material Chemistry, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, P. R. China State key Laboratory of Biocontrol, School of Life Sciences, Zhongshan University, Guangzhou, 510275, People Republic of China; 2Center for Proteomics, Department of Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People's Republic of China Department of Pharmacology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, P.R. China Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, United States Authors' Affiliations: Departments of 1Pathology and 2Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; and Departments of 3Pathology and 4Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas Department of Cardiology, West China Hospital of Sichuan University, Chengdu, P.R. China. College of Chemistry and Chemical Engineering, Advanced Catalytic Engineering Research Center of the Ministry of Education, Hunan University, Changsha 410082, China Harbin Medical University, Harbin, China Department of Respiratory Medicine The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan China Collaborative Innovation Center of Chemical Science and Engineering; Key Laboratory of Advanced Energy Materials Chemistry (MOE); College of Chemistry; Nankai University; Tianjin 300071 School of Material and Chemical Engineering; Tongren University; Tongren 554300; China Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan 410082, China Tea Science Research Institute, College of Horticulture, Nanjing Agricultural University, Nanjing, China. Department of Epidemiology and Biostatistics, West China School of Public Health, Sichuan University, Chengdu, People's Republic of China. Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China Department of Orthopedics China‐Japan Union Hospital Jilin University Changchun Jilin China Tianjin Normal University College of Mechanical Science and Engineering, Northeast Petroleum University, Daqing 163318, China Guangdong Center for Disease Control and Prevention, Guangzhou, People's Republic of China Centre for Organic Photonics & Electronics, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland 4072, Australia College of Agro‐grassland Science Nanjing Agricultural University Nanjing China Department of Gastroenterology Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China Second People's Hospital of Sichuan Province, Chengdu, P.R. China. 2Department of Pediatrics, Texas Children's Cancer Center, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas. Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China Department of Pathology, Hebei Medical University, Shijiazhuang, Hebei, China Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802; Department of Agronomy, Purdue University, West Lafayette, Indiana 47907-1150 Peking University Sixth Hospital/Institue of Mental Health, Beijing, China; National Clinical Research Center for Mental Disorders, Beijing, China The First Hospital, Hebei Medical University, Shijiazhuang, China College of Forestry, Nanjing Forestry University, Nanjing, Jiangsu 210037, China; Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, Jiangsu 210037, China Department Of Otolaryngology Head and Neck Surgery, Jinan University, Guangzhou, Guangdong; Department Of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China. Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China State Key Laboratory of Natural Medicines Jiangsu Key Laboratory of Carcinogenesis and Intervention Key Laboratory of Drug Quality Control and Pharmacovigilance China Pharmaceutical University Nanjing China Department of Obstetrics and GynecologyIndiana University Indianapolis Indiana USA Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, China Key Laboratory of Chicken Genetics and Breeding Ministry of Agriculture and Rural Affairs Key Laboratory of Animal Genetics, Breeding and Reproduction Education Department of Heilongjiang Province College of Animal Science and Technology Northeast Agricultural University Harbin P. R. China CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and Engineering University of Science and Technology of China Hefei Anhui 230026 China Department of Gastroenterology, Shengjing Hospital Affiliated to China Medical University, Sanhao Street 36, Shenyang, Liaoning, PR China School of Science, RMIT University, Melbourne, VIC 3000, Australia WuXi University BGI-Shenzhen, Shenzhen 518083, China; State Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen 518083, China Department of Otorhinolaryngology‐Head and Neck Surgery Seoul National University Hospital Seoul South Korea Guangdong Center for Disease Control and Prevention, Guangzhou, China. Xi’an University of Architecture and Technology, Xi’an, Shaanxi, People’s Republic of China Department of Spine Surgery, Honghui Hospital of Xi’an Jiaotong University Health Science Center, Xi’an, China Department of Thoracic Surgery, Beijing Chao‐yang Hospital Capital Medical University 100020 Beijing China Departments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA Department of Pathology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University , Harbin 150030 , P.R. China Liaoning Key Laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials College of Chemistry Liaoning University Shenyang 110036 China State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200030, China State Key Laboratory for Crop Genetics and Germplasm Enhancement Jiangsu Plant Gene Engineering Research Center Nanjing Agricultural University Nanjing 210095 China Fifth Medical Department, University Hospital Mannheim, Heidelberg University, 68167 Mannheim, Germany Department of Orthopaedics General Hospital of Tianjin Medical University Tianjin China Key Laboratory of Structure and Functional Regulation of Hybrid Materials (Anhui University), Ministry of Education, Institutes of Physical Science and Information Technology, Anhui University, Hefei 230601, P. R. China Guangzhou University of Chinese Medicine, Guangzhou, China Xiangya School of Medicine, Central South University, Changsha, China Respiratory and Critical Care Medicine, Mianyang Central Hospital, University of Electronic Science and Technology of China, Mianyang, Sichuan 621000, P.R. China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials; Ministry of Education; Shandong University; Jinan 250061; People's Republic of China The Second People's Hospital of Sichuan Province, Chengdu, P. R. China. State Key Laboratory of Analytical Chemistry for Life Science; School of Chemistry and Chemical Engineering; Nanjing University; Nanjing; China Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan Province, China State Key Laboratory of ASIC & System, School of Information Science and Technology, Fudan University, Shanghai 200433, China Department of Cardiology, The Second Affiliated Hospital of Soochow University, Suzhou, China Immunization Program Department, Gansu Provincial Center for Disease Control and Prevention, Lanzhou, Gansu, China Hepatology Unit and Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Center for Proteomics, Department of Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People's Republic of China, and State Key Laboratory of Biocontrol, School of Life Sciences, Zhongshan University, Guangzhou 510275, People's Republic of China Center for Proteomics, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China Department of Chemistry, Laboratory of Mesoscopic Chemistry, Institute of Theoretical and Computational Chemistry, Nanjing University, Nanjing 210093, People’s Republic of China Department of Chemistry Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology Tsinghua University Beijing 100084 China Department of Hepatobiliary Surgery Shaanxi Provincial People’s Hospital Xi’an China Xi’an Modern Chemistry Research Institute, Xi’an 710065, China College of Chemical Engineering Sichuan University Chengdu Sichuan China Univ Rennes CNRS ISCR-UMR 6226 35000 Rennes France CAS Key Laboratory of Soft Matter Chemistry iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Department of Polymer Science and Engineering University of Science and Technology of China Hefei 230026 China Hebei Province Chest Hospital The Center of Lung Cancer Prevention Shijiazhuang China State Key Laboratory of Chemo/Biosensing and Chemometrics; College of Chemistry and Chemical Engineering; Hunan University; Changsha; China Collaborative Innovation Center of Chemical Science and Engineering, Key Laboratory of Advanced Energy Materials Chemistry (MOE), College of Chemistry, Nankai University, Tianjin 300071, P. R. China Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Guangdong Provincial Engineering and Technological Research Center for Drug Carrier Development, Department of Biomedical Engineering, Jinan University, Guangzhou 510632, China Department of Orthopaedics, Xiangya Hospital Central South University Changsha China; Key Laboratory of Aging‐related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital Central South University Changsha China; Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University Changsha China College of Materials Science and Engineering, Xi’an University of Architecture and Technology, Xi’an 710055, China Institute for Chemical Research Kyoto University Uji, Kyoto 611-0011 Japan Laboratory for Polymer Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China China University of Petroleum (Beijing), Beijing 102249, China The Key Laboratory of Space Applied Physics and Chemistry; Ministry of Education and Shanxi Key Laboratory of Macromolecular Science and Technology; School of Science; Northwestern Polytechnical University; Xi'an Department of Pulmonary and Critical Care Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China Department of Physiology and Pathophysiology, Qingdao University Medical College, Qingdao, P.R. China. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, People's Republic of China Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China Department of Ultrasonography, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, Zhejiang Province, China Center for the Study of Itch, Washington University School of Medicine Pain Center, St. Louis, MO 63110, USA; Departments of Anesthesiology, Washington University School of Medicine Pain Center, St. Louis, MO 63110, USA Institute of Non-Communicable Disease Control and Prevention, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China Department of Chemistry, University of Nebraska—Lincoln, Lincoln, Nebraska 68588 Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, People’s Republic of China Hefei National Laboratory for Physical Science at Microscale and Departments of Chemistry and Material Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China. Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, P. R. China Clean Nano Energy Center, State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, People’s Republic of China Midwest Center for Structural Genomics and Structural Biology Center, Biosciences Division, Argonne National Laboratory, Argonne, IL 60439; Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, China Department of Pulmonary and Critical Care Medicine, National Clinical Research Center of Respiratory Diseases, Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing 100020, China Beijing Chao-Yang Hospital, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing, China. Centre for Disease Control and Prevention of Guangdong province Guangzhou Department of Materials Science and Engineering; National University of Singapore; Singapore Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences Lanzhou P. R. China School of Software, Shandong University, Jinan, Shandong, China State Key Laboratory of Tree Genetics and Breeding, Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China; Kernel-Apricot Engineering and Technology Research Center of State Forestry and Grassland Administration, Zhengzhou 450003, China; Key Laboratory of Non-Timber Forest Germplasm Enhancement and Utilization of National Forestry and Grassland Administration, Zhengzhou 450003, China School of Material Science and Engineering, University of Jinan, 250022, Jinan, P. R. China Department of Neurology Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine Nanjing China Department of Pharmacology and Chemical BiologyInstitute of Medical Sciences Shanghai China State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Animal Science and Technology, Guangxi University, Nanning, China Departement für Chemie und Biochemie; Universität Bern; 3012 Bern, Switzerland Rigel Pharmaceuticals Inc., South San Francisco, California 94080, United States Department of Respiratory Medicine The Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing China Key Laboratory of Space Applied Physics and Chemistry; Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology; School of Science; Northwestern Polytechnical University; Xi'an 710072, P. R. China Department of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853; Key Laboratory of Pediatric Hematology and Oncology Ministry of Health Pediatric Translational Medicine Institute Shanghai Children's Medical Center School of Medicine Shanghai Jiao Tong University China; Fujian Children's Hospital Fujian Branch of Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine China; Department of Pharmacology and Chemical Biology School of Basic Medicine and Collaborative Innovation Center for Translational Medicine School of Medicine Shanghai Jiao Tong University China Fujian Normal University School of Medicine, Henan University, Kaifeng, Henan 475004, China Department of Hepatobiliary Surgery, Xingtai People's Hospital of Hebei Medical University, Xingtai, Hebei 054001, P.R. China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials; Ministry of Education; Shandong University; Jinan 250061, People's Republic of China Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA Department of Liver Surgery, Liver Cancer Institute and Zhongshan Hospital, and Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University), Ministry of Education, Fudan University, Shanghai, People's Republic of China Department of Pathology University of Iowa Carver College of Medicine Iowa City IA USA State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China Department of Chemistry and Chemical Biology Northeastern University Boston MA 02115 USA Liver Cancer Institute, Zhongshan Hospital Fudan University Shanghai P. R. China; Key Laboratory of Carcinogenesis and Cancer Invasion Fundan University, Ministry of Education Shanghai P. R. China Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China Changchun Customs Technology Center , 4448 Freedom Road, Changchun , China Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China Joint National Laboratory for Antibody Drug Engineering, Key Laboratory of Cell and Molecular Immunology, School of Medical Sciences, Henan University, Kaifeng 475004, P.R. China. Beijing Advanced Innovation Center for Soft Matter Science and Engineering, State Key Laboratory of Chemical Resource Engineering, College of Materials Science and Engineering, Analysis and Test Center, Beijing University of Chemical Technology, North Third Ring Road 15, Chaoyang District, Beijing 100029, China Key Laboratory of Meat Processing of Sichuan Chengdu University Chengdu China Key Laboratory for Biobased Materials and Energy of Ministry of Education, Guangdong Provincial Engineering Technology Research Center for Optical Agriculture, College of Materials and Energy, South China Agricultural University, Guangzhou 510642, P. R. China Research Center of Machine Vision Engineering of Hebei University Key Laboratory of Digital Medical Engineering of Hebei Province College of Electron and Information Engineering Hebei University Baoding 071002 P. R. China Department of Ophthalmology Shanghai Tenth People's Hospital Tongji University School of Medicine Shanghai China Department of Orthopaedic Surgery , Sir Run Run Shaw Hospital, , No. 3, Qingchun Road East, Hangzhou, 310016 , P.R. China; Zhejiang University School of Medicine , Sir Run Run Shaw Hospital, , No. 3, Qingchun Road East, Hangzhou, 310016 , P.R. China; Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province , No. 3, Qingchun Road East, Hangzhou, 310016 , P.R. China Department of Geology and Geophysics, Yale University, New Haven, CT 06520-8109; Department of Orthopedics, The Second Xiangya Hospital of Central South University, Changsha 410011, China Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, Ministry of Education, Shandong University, Jinan 250061, China State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China Department of Chemistry, Yonsei University, Seoul 03722, Republic of Korea State Key Laboratory of Oncology in Southern China, Guangzhou;; Medical Imaging and Minimally Invasive Interventional Center, Cancer Center, Sun Yat-sen University, Guangzhou, People's Republic of China Department of Endocrinology The Second affiliated Hospital of Harbin Medical University Harbin China Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College Huazhong University of Science & Technology Wuhan China College of Chemistry, Chemical Engineering and Materials Science Soochow University No.199 Renai Road Suzhou Jiangsu Sheng 215123 P. R. China Department of Pulmonary and Critical Care Medicine, Center for Respiratory Diseases, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Beijing; Department of Respiratory Medicine, Capital Medical University, Beijing Beijing Huilongguan Hospital Peking University Huilongguan Clinical Medical School Beijing China Jilin Ginseng Academy Changchun University of Chinese Medicine Changchun P. R. China Centre for Organic Photonics & Electronics, School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Queensland 4072, Australia Department of Chemistry, Auburn University, Auburn, Alabama 36849-5312 Depatment of Biotherapy, Cancer Center West China Hospital, Sichuan University Chengdu China; West China School of Medicine West China Hospital, Sichuan University Chengdu China State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, People’s Republic of China Department of Blood Transfusion, Chinese PLA General Hospital, Beijing 100853, China Institute of Atomic and Molecular Physics, Jilin University, Changchun 130012, China University of Science and Technology of China Department of Emergency, The Affiliated Hospital of Qingdao University, Qingdao, China Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China Department of Spine Surgery, The Sixth Affiliated Hospital of Xinjiang Medical University, Xinjiang Urumqi, China State Key Laboratory of Hybrid Rice College of Life Sciences, Wuhan University Wuhan 430072 China Department of Pathology School of Medicine Nankai University Tianjin China Department of Ophthalmology, Heze Municipal Hospital, Heze 274000, Shandong, China Department of Orthopedic, Chongqing Jiangbei hospital of Traditional Chinese Medicine, Chongqing 400020, China Institute of Chinese Materia Medica, Chinese Academy of Chinese Medical Sciences, Beijing, China; Affiliated Hospital of Qingdao University, Qingdao, China Liver Failure Treatment and Research Center, The Fifth Medical Center of PLA General Hospital, Beijing, China Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing, China State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing, Jiangsu 210093, China School of Public Health, Southwest Medical University, Luzhou, China College of Biotechnology and Pharmaceutical Engineering; Nanjing Tech University; Nanjing 210000; China; State Key Laboratory of Materials-Oriented Chemical Engineering Department of Pathology, University of Washington, Seattle, WA, USA. Departments of Radiology and Department of Neurobiology, Beijing Key Laboratory of Neural Regeneration and Repair, Beijing Laboratory of Brain Disorders (Ministry of Science and Technology), Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China; Iowa State University Department of Chemistry, , Ames, Iowa 50011 Laboratory of Theoretical and Computational Chemistry; Institute of Theoretical Chemistry; Jilin University; Changchun 130023; People's Republic of China Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science; College of Life Sciences and Oceanography; Shenzhen University; Shenzhen 518060; China Department of Pharmaceutics College of Pharmaceutical Sciences Soochow University Suzhou 215123 China Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life Sciences Lanzhou University Lanzhou 730000 China Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041 Sichuan, China School of Electrical Engineering, Xi’an University of Technology, Xi’an 710048, China College of Biotechnology and Pharmaceutical Engineering; Nanjing Tech University; Nanjing; China; State Key Laboratory of Materials-Oriented Chemical Engineering Keck School of Medicine, University of Southern California, Los Angeles, California College of Agronomy Sichuan Agricultural University Chengdu China From the Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China. State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, P. R. China School of Computer and Information Engineering, Heilongjiang Provincial Key Laboratory of Electronic Commerce and Information Processing, Harbin University of Commerce, Harbin 150028, China †Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637 Department of Molecular Biology, Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center , 6000 Harry Hines Blvd., Dallas, TX 75390 , USA Department of Chemistry, University of Nebraska—Lincoln, Lincoln, Nebraska 68588, United States Department of Anatomy, Guangzhou University of Chinese Medicine, Guangzhou, China Department of Social Medicine and Health Management, Huazhong University of Science and Technology, China Department of Dermatology, Hospital of Weifang People,Weifang, (Department of Dermatology, the first affiliated Hospital of Weifang Medical College) Snapdragon Chemistry Inc., 300 Second Ave, Waltham, Massachusetts 02451, United States Department of Chemistry, Shanghai Normal University, Shanghai 200234, China, and Chemical & Biomolecular Engineering Department, University of California, Los Angeles, California 90095 Key Laboratory of Plant Resources Institute of Botany, Chinese Academy of Sciences Beijing China; China National Botanical Garden Beijing China Center for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Sun Yat-Sen University, University City, Guangzhou 510006, People’s Republic of China, School of Life Sciences, Xiamen University, Xiamen 361005, People’s Republic of China, and Center of Clinical Laboratory, Xiamen Zhongshan Hospital, Xiamen University, Xiamen 361004, Fujian, People’s Republic of China Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588 Zhengzhou Tobacco Research Institute, China National Tobacco Corporation, Zhengzhou 450001, China Committee on Medical Physics Department of Radiology University of Chicago MC 2026, 5841 South Maryland Avenue Chicago IL 60637 USA Departments of Laboratory Medicine College of Physics and Information Engineering; Henan Normal University; Xinxiang 453007; China Department of Ophthalmology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China Department of Laboratory Medicine, The First Hospital of Jiaxing Affiliated Hospital of Jiaxing University Jiaxing China Department of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, Hebei Province, China. Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China. CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China School of Chemistry and Chemical Engineering Hunan University of Science and Technology Xiangtan 411201 China; Key Laboratory of Theoretical Chemistry and Molecular Simulation of Ministry of Education Hunan University of Science and Technology Xiangtan 411201 China; Hunan Provincial University Key Laboratory of QSAR/QSPR Xiangtan 411201 China State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China Key Laboratory for Green Chemical Process of Ministry of Education; Hubei Key Laboratory for Novel Reactor and Green Chemistry Technology; Hubei Engineering Research Center for Advanced Fine Chemicals; School of Chemical Engineering and Pharmacy; Wuhan Institute of Technology Departments of Pharmacology and Molecular Toxicology, Molecular Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, MA 01655; and Department of Medicine, Cardiology Research Division, Wayne State University, Detroit, MI 48201 Department of Endocrinology The Second affiliated Hospital of Harbin Medical University Harbin Heilongjiang China Department of Plant and Soil Sciences, University of Delaware, Newark, Delaware 19716, United States Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin 150030, PR China; Key Laboratory of Animal Genetics, Breeding and Reproduction, Education Department of Heilongjiang Province, Harbin 150030, PR China; College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, PR China College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, PR China Pfizer Global Research and Development, La Jolla Laboratories, 10770 Science Center Drive, San Diego, California 92121 Departments of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States Co-Innovation Center for Sustainable Forestry in Southern China, Nanjing Forestry University , Nanjing 210037 , China; College of Forestry, Nanjing Forestry University , Nanjing 210037 , China MOE Key Laboratory of Fundamental Physical Quantities Measurement, Hubei Key Laboratory of Gravitation and Quantum Physics, School of Physics, Huazhong University of Science and Technology , 1037 Luoyu Road, Wuhan 430074, People’s Republic of China College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China Chinese Academy of Sciences Department of Gynecology and Obstetrics, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310006, China Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA Department of Materials Science and Engineering, National University of Singapore, Singapore 117576 State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China School of Science RMIT University Melbourne VIC 3000 Australia From the Institute for Nutrition and Food Safety, Liaoning Provincial Center for Disease Control and Prevention, Shenyang, China Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China Shanghai Institute of Cardiovascular Diseases Zhongshan Hospital Fudan University Shanghai China 0000 0001 0708 1323 grid.258151.a School of Pharmaceutical Science Jiangnan University 1800 Lihu Avenue 214122 Wuxi Jiangsu People’s Republic of China Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University Shenyang China School of Life Sciences and Technology, Shanghai Jiao Tong University, Shanghai 200240, China The Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Center for Human Genome Research Cardio‐X Institute, Huazhong University of Science and Technology Wuhan China Department of Neonatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China Cancer Center The First Hospital of Jilin University Changchun 130021 China Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi, P. R. China Department of Polymer Science The University of Akron Akron OH 44325 USA National–Local Joint Engineering Laboratory of New Energy Photovoltaic Devices Key Laboratory of Digital Medical Engineering of Hebei Province College of Electron and Information Engineering Hebei University Baoding 071002 P. R. China Department of Medical Imaging Fuzhou General Hospital, Second Military Medical University Fuzhou Fujian Province China Xi’an Modern Chemistry Research Institute, Xi’an, Shaanxi 710065, China State Key Laboratory of Radiation Medicine and Protection, School for Radiological and interdisciplinary Sciences (RAD-X) and Collaborative Innovation Centre of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, China The Institute for Advanced Studies Wuhan University Wuhan 430072 P. R. China CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 China; University of Chinese Academy of Sciences Beijing 100049 China State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals, Lanzhou University of Technology, Lanzhou 730050, Gansu, China; School of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, Gansu, China Department of Pediatric Surgery, Key Laboratory of Health Ministry for Congenital Malformation, Shengjing Hospital, China Medical University, Shenyang, China State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, People’s Republic of China Department of Pharmacy, Affiliated Hospital of Weifang Medical University, Weifang, Shandong Province, China Department of Colorectal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, P. R. China Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People’s Republic of China; School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, People’s Republic of China Shaanxi Key Laboratory of Molecular Biology for Agriculture College of Animal Science and Technology, Northwest A&F University Yangling Shaanxi China; College of Life Sciences Xinyang Normal University, Institute for Conservation and Utilization of Agro‐Bioresources in Dabie Mountains Xinyang Henan China Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China Key Laboratory of Molecular Biophysics of the Ministry of Education College of Life Science and Technology and Center for Human Genome ResearchHuazhong University of Science and Technology Wuhan P.R. China |
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