http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_6840bd1fc114de93ae7cde3e7c81da44
Outgoing Links
Predicate | Object |
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family-name | Fei Chen Chen |
name | Fei Chen |
given-name | Fei |
organization-name | Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211800, China Medical College of Jinhua Profession and Technology College, Jinhua 321000, China. [email protected] Key Laboratory for Special Functional Materials of Ministry of Education National & Local Joint Engineering Research Center for High-Efficiency Display and Lighting Technology Collaborative Innovation Center of Nano Functional Materials and Applications, Henan University, Kaifeng, 475004, P. R. China Department of Chemical Engineering and Human Mobility Research Centre, Queen’s University, Kingston, Canada School of Environment, Tsinghua University, Beijing 100084, China Department of Physics, Boston University, Boston, MA 02215, USA. State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine (SJTUSM) & Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), Shanghai 200031, China. [email protected]. Chinese National Center for Drug Screening, CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China Department of Spine Surgery, Second Xiangya Hospital of Central South University, Changsha 410011, China. [email protected] School of Control and Computer Engineering, North China Electric Power University, Beijing 102206, China Department of Radiology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China; Department of Radiology, Yancheng Third People’s Hospital, Yancheng, Jiangsu, China Changchun Institute of Optics, Fine Mechanics and Physics School of Chemistry and Chemical Engineering, Hefei University of Technology, Anhui Key Laboratory of Controllable Chemical Reaction & Material Chemical Engineering, Hefei, Anhui 230009, P.R. China grid.458441.8 0000000093395152 Center for Natural Products Research Chengdu Institute of Biology, Chinese Academy of Sciences 610041 Chengdu People’s Republic of China; grid.410726.6 0000000417978419 University of Chinese Academy of Sciences 100049 Beijing People’s Republic of China Evidence‐Based Nursing Center School of Nursing, Lanzhou University Lanzhou China Health Management Center Renji Hospital of Medical School of Shanghai Jiaotong University Shanghai China Rutgers–Robert Wood Johnson University Hospital CAS Key Laboratory of Materials for Energy Conversion, Department of Materials Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Hefei, Anhui 230026, China Department of Otorhinolaryngology Head & Neck Surgery, First Affiliated Hospital of Guiyang Medical College, Guiyang 550004, China. [email protected] Department of Spinal Surgery, Second Xiangya Hospital, Central South University, Changsha, China. School of Mechatronic Engineering, China University of Mining and Technology, Xuzhou, 221116, China Shaanxi Key Laboratory of Energy Chemical Process Intensification School of Chemical Engineering and Technology Xi'an Jiaotong University Xi'an Shaanxi 710049 P. R. China College of Environmental Science and Engineering, Hunan University 2 , Changsha 410082, People's Republic of China School of Science Western Sydney University Penrith NSW 2751 Australia; Hawkesbury Institute for the Environment Western Sydney University Penrith NSW 2751 Australia; College of Life and Environmental Sciences Hangzhou Normal University Hangzhou 310036 China CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, 100101, Beijing, PR China; China National Center for Bioinformation, Beijing 100101, PR China; University of Chinese Academy of Sciences, Beijing 100049, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China; Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China Organisch-Chemisches Institut Universität Heidelberg Im Neuenheimer Feld 270 69120 Heidelberg Germany Department of Spine Surgery, The Second Xiangya Hospital, Central University, Changsha, Hunan 410011, P.R.�China Department of Nuclear Medicine Nanjing Medical University Affiliated Wuxi People's Hospital Wuxi PR China CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, People’s Republic of China; University of Chinese Academy of Sciences, Beijing, People’s Republic of China; State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Urumqi, Xinjiang, People’s Republic of China Key Laboratory of Pu-er Tea Science; Ministry of Education; Yunnan Agricultural University; Kunming 650201; China South University of Science and Technology of China, Department of Electrical and Electronic Engineering, No. 1088, Xueyuan Road, Xili, Nanshan District, Shenzhen, Guangdong 518055, China School of First Clinical Medical Science Nanjing Medical University Nanjing China Department of Epidemiology The Johns Hopkins Bloomberg School of Public Health Baltimore MD USA State Key Laboratory of Water Resources Engineering and Management, Wuhan University, Wuhan 430072, China Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Department of Cardiology, West China Hospital, Sichuan University , Chengdu , China Authors' Affiliations: 1National Human Genome Center of Rui-Jin Hospital, Shanghai Jiaotong University School of Medicine; and 2Shanghai-MOST Key Laboratory for Disease and Health Genomics, Chinese National Human Genome Center at Shanghai, Shanghai, China School of Transportation Engineering, East China Jiaotong University, Nanchang 330013, China Department of General Surgery Zhujiang Hospital Guangzhou China; Institute of Biomedical Engineering Southern Medical University Guangzhou China Department of Spine Surgery, The Second Xiangya Hospital of Central South University, Changsha Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing. Department of Orthopaedics, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China, and College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, 2999 North Renmin Lu, Shanghai 201620, China Department of Pathology & Laboratory Medicine, UMD-New Jersey Medical School , Newark Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China Laboratory of Pathology, West China Hospital, Sichuan University, Key Laboratory of Transplant Engineering and Immunology, Sichuan University, Chengdu, China. Department of Clinical Medicine, Medical College, University of South China, Hengyang, Hunan 421001, P.R. China Department of Diagnostic Ultrasound, Peking University First Hospital, Beijing 100034, China. Foundation for Applied Molecular Evolution (FfAME), 720 SW Second Avenue, Suite 201, Gainesville, Florida 32601, United States; The Westheimer Institute for Science and Technology (TWIST), 720 SW Second Avenue, Suite 208, Gainesville, Florida 32601, United States Department of Chemistry and Biochemistry Concordia University Montreal H4B 1R6 Department of Radiology, Affiliated Yancheng Hospital, School of Medicine, Southeast University, Yancheng, Jiangsu, China CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People’s Republic of China College of Chemistry and Chemical Engineering Xinjiang University Urumqi 830046 People's Republic of China Prince Philip Dental Hospital, The University of Hong Kong, SAR, People’s Republic of China Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and Engineering College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China China CDC Key Laboratory of Radiological Pretection and Nuclear Emergency, National Institute for Radiological Protection, China CDC, Beijing 100088, People’s Republic of China; Key Lab of Nuclear Radiation and Nuclear Energy Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Statistics and Decision Sciences, Janssen Research & Development LLC, West Bridgewater, USA Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 State Key Laboratory of Agricultural Microbiology and College of Life Science and Technology Huazhong Agricultural University Wuhan 430070 China Laboratory of Pathology West China Hospital Sichuan University Chengdu China Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province, Key Laboratory of Molecular and Cellular Biology of Ministry of Education, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei 050024, China Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China Key Laboratory of Urban Pollutant Conversion Department of Environmental Science and Engineering University of Science & Technology of China Hefei 230026 China; Key Laboratory of the Three Gorges Reservoir Region's Eco‐Environment Ministry of Education College of Environment and Ecology Chongqing University Chongqing 400045 China CAS Key Laboratory of Genome Sciences & Information China National Center for Bioinformation Chinese Academy of Sciences Beijing Institute of Genomics Beijing 100101 China; University of Chinese Academy of Sciences Beijing 100049 China; State Key Laboratory of Pathogenesis, Prevention Treatment of High Incidence Diseases in Central Asia Xinjiang China; Beijing Key Laboratory of Genome and Precision Medicine Technologies Beijing China School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Department of Cardiothoracic Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang Province, China. Laboratory of Pharmaceutical Biotechnology Nanjing University Nanjing China; Department of Neurology Affiliated Drum Tower Hospital Nanjing Medical University Nanjing China Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410078, China Department of Spine Surgery, Second Xiangya Hospital of Central South University, Changsha 410011, China. Cancer Institute, Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, Zhejiang province, China. Beijing Tongren Eye Center,Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab,Beijing 100730, China. Department of Cardiology West China Hospital, Sichuan University Chengdu China The Fish Molecular Genetics and Biotechnology Laboratory, Department of Fisheries and Allied Aquacultures, Program of Cell and Molecular Biosciences, Aquatic Genomics Unit, Auburn University, Auburn, Alabama 36849 Beijing Institute of Genomics, Chinese Academy of Sciences, No. 7 Beitucheng West Road, Beijing, 100029, China Laboratory of Prof. Hadjikhani, EPFL-SV-BMI-GRHAD AAB023, Station 15, CH-1015 Lausanne, Switzerland, Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Coastal Ecosystems Research Station of the Yangtze River Estuary, Institute of Biodiversity Science, School of Life Sciences, Fudan University, 2005 Songhu Road, Shanghai 200438, People's Republic of China Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China Department of Electrical and Electronic Engineering, Southern University of Science and Technology 2 , Xueyuan Road 1088#, Xili, , Shenzhen, China [email protected] , [email protected] , [email protected]; Nanshan District 2 , Xueyuan Road 1088#, Xili, , Shenzhen, China [email protected] , [email protected] , [email protected] Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China. Department of Gastroenterology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.; Department of Gastroenterology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. Department of Chemistry & Biochemistry, Concordia University CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety; National Center for Nanoscience and Technology of China; Beijing 100190; People's Republic of China Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science; College of Chemistry and Chemical Engineering; Central South University; Changsha; China Key Laboratory of Flexible Electronics (KLOFE) Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing Tech University 30 South Puzhu Road Nanjing 211816 P. R. China †Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505; and Department of Anesthesiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina Southern University of Science and Technology Department of Electrical and Electronic Engineering, , Shenzhen, China Department of Otorhinolaryngology, West China Hospital, Sichuan University, Chengdu. Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, People’s Republic of China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha, China. Department of Sports Medicine, The First Affiliated Hospital of Shenzhen University Shenzhen Second People's Hospital Shenzhen Guangdong China Department of Anesthesiology, The University of North Carolina, Chapel Hill, North Carolina Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing, China Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China Department of Chemistry, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong, China, and Department of Chemistry, Fudan University, Shanghai 200433, China Department of Otorhinolaryngology-Head and Neck Surgery, West China Hospital of Sichuan University Key Laboratory of Natural Products of Henan Academy of Science, Zhengzhou 450002, PR China Department of Nephrology, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China School of Life Sciences, Zhengzhou University, Zhengzhou, China Hainan University College of Tropical Crops, Sanya Nanfan Research Institute, , Haikou 570228, China; Hainan Yazhou Bay Seed Laboratory , Sanya 572025, China College of Computer and Data Science Fuzhou University Fuzhou China CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics Chinese Academy of Sciences Beijing 100101 P. R. China; University of Chinese Academy of Sciences Beijing 100049 P. R. China University of Texas at Dallas Department of Electrical Engineering, , EC 33, 800 West Campbell Road, Richardson, Texas 75083-0688 University of Hong Kong, China Department of Speech and Hearing Sciences University of Hong Kong Hong Kong State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China Department of Chemical and Environmental Engineering University of Nottingham Ningbo China Ningbo 315100 China Department of Spine Surgery Department of Pharmaceutical Sciences; Wayne State University; Detroit, MI USA Department of Pathology NYU Langone Health New York New York USA Department of Gastroenterology Changzheng Hospital Second Military Medical University Shanghai China Department of Biological Engineering, Massachussetts Institute of Technology (MIT), Cambridge, MA, USA. Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University Hefei China; Institute for Liver Diseases of Anhui Medical University Hefei China Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA, [email protected]. Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China, and Department of Chemistry, Fudan University, Shanghai 200433, China [email protected] eHealthMe, Madison, Wisconsin Foundation for Applied Molecular Evolution (FfAME), 720 SW Second Avenue, Suite 201, Gainesville, Florida 32601, United States; The Westheimer Institute for Science and Technology (TWIST), 720 SW second Avenue, Suite 208, Gainesville, Florida 32601, United States; The CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China Department of Gastroenterology Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China; Institution of Gastroenterology Zhejiang University Hangzhou China 1The Health Effects Laboratory Division, National Institute for Occupational Safety and Health;; 2Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia; and Email: [email protected]. a Quantitative Decision Strategies , Janssen Research & Development , Raritan , New Jersey , USA Department of Gynaecology and Obstetrics Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China Department of Pathology and Institute of Clinical Pathology, West China Hospital Sichuan University Chengdu PR China Department of Physics; Boston University; Boston; USA School of Transportation, Southeast University, Nanjing, Jiangsu, China Department of Radiobiology, School of Radiation Medicine and Protection, Medical College of Soochow University, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, Suzhou, China. School of Pharmacy, Ningxia Engineering and Technology Research Center for Modernization of Traditional Chinese Medicine, and Key Laboratory of Traditional Chinese Medicine Modernization, Ministry of Education, Ningxia Medical University Department of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai, People's Republic of China; Department of Respiratory Medicine, Changxing People's Hospital of Zhejiang, Huzhou, Zhejiang 313100, P.R. China School of Computer Engineering, Nanyang Technological University Institute of Clinical Pathology West China Hospital Sichuan University Chengdu Sichuan China Department of Stem Cell and Regenerative Biology, Harvard University , Cambridge, MA 02138 , USA; Broad Institute of MIT and Harvard , Cambridge, MA 02142 , USA Key Laboratory of Novel Materials for Sensor of Zhejiang Province, College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China College of Life Science, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou, China Department of Neurosurgery, The Sixth People’s Hospital of Nantong, Nantong, Jiangsu, China Department of Thyroid Surgery Zhujiang Hospital Southern Medical University Guangzhou 510280 China Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Xueyuan Road 1088#, Xili, Nanshan District, Shenzhen 518055, China [email protected] State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China Department of Gastroenterology, The Second Affiliated Hospital of Shandong First Medical University, Taishan Street No. 366, Tai’an, 271000 Shandong Province, China State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China College of Materials and Environmental Engineering, Hangzhou Dianzi University, 310018 Hangzhou, China College of Pharmaceutics, Jinhua Polytechnic, Jinhua, Zhejiang, China (mainland) College of Environmental Science and Engineering, Hunan University, Changsha, People’s Republic of China College of Biomedical Engineering, Chongqing Medical University, State Key Laboratory of Ultrasound Engineering in Medicine Co-Founded by Chongqing and The Ministry of Science and Technology, Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing, China (mainland) Department of Nuclear Medicine, Ganzhou Tumour Hospital , Ganzhou , China Laboratory Animal Engineering Research Center of Ganzhou Gannan Medical University Jiangxi China Institute of Life Sciences, College of Biological Science and Engineering, Fuzhou University, Fuzhou, Fujian 350108, P.R. China CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry Chinese Academy of Sciences (CAS) University of Chinese Academy of Sciences Beijing 100190 P.R. China; Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072 P.R. China Laboratory of Polymer Materials and Engineering; Ningbo Institute of Technology; Zhejiang University; Ningbo 315100; China Department of Anesthesiology, University of North Carolina, Chapel Hill, North Carolina, CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences , Beijing 100101 , China Foundation for Applied Molecular Evolution (FfAME), 720 SW 2nd Avenue, Suite 201, Gainesville, FL 32601;; The Westheimer Institute for Science and Technology (TWIST), 720 SW 2nd Avenue, Suite 208, Gainesville, FL 32601; Department of Haematology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China. University of Texas at Dallas Department of Electrical Engineering, , Richardson, Texas 75083 Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Genetics, Breeding and Multiple Utilization of Corps, Ministry of Education, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou, China Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province, College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, Hebei, China University of Texas at Dallas Department of Electrical Engineering, EC 33, , 800 West Campbell Road, Richardson, Texas 75083-0688 Department of Hepatobiliary Surgery, The Second Hospital of Jiaxing, Jiaxing, Zhejiang 314000, P.R. China Division of Speech and Hearing Sciences, Prince Philip Dental Hospital, The University of Hong Kong , 34 Hospital Road, Hong Kong [email protected] Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Med, Chicago, IL. Evidence-based Nursing Center , School of Nursing, , Lanzhou, China; Lanzhou University , School of Nursing, , Lanzhou, China; Evidence-based Medicine Center , School of Basic Medical Sciences, , Lanzhou, China; Lanzhou University , School of Basic Medical Sciences, , Lanzhou, China State Key Laboratory of Drug Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China Department of Chemistry and Biochemistry, Concordia University, Montreal, QC, Canada Biotechnology and Planetary Protection Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109, USA Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Xueyuan Road 1088#, Xili, Nanshan District, Shenzhen 518055, China Media Arts and Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Broad Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA Department of Synopsis of the Golden Chamber, School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin 150040, China Institute of Life Sciences, Fuzhou University, Fuzhou, Fujian Province, P. R.China School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China. [email protected] Department of Neurosurgery, Zhuji People's Hospital of Zhejiang Province, Zhuji Affiliated Hospital of Wenzhou Medical University Zhuji 311800, Zhejiang, People's Republic of China. Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China; Department of Ophthalmology, Tengzhou Central People’s Hospital of Shandong Province, Shandong, China Department of Pharmaceutical Sciences Eugene Applebaum College of Pharmacy and Health Sciences Wayne State University Detroit MI USA Assistant Professor, Department of Anesthesiology, and Co-Director, TEACHER Lab, University of North Carolina at Chapel Hill School of Medicine Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and Institute of Polymer Science and Engineering, Lanzhou University, Lanzhou 730000, China Department of Gastroenterology, Zhuji People's Hospital of Zhejiang Province, Shaoxing, Zhejiang 311800, P.R. China Max Planck Institute for Polymer Research, 55128 Mainz, Germany College of Science China Agricultural University Beijing China Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China Asian Elephant Research Center of National Forestry and Grassland Administration, Kunming 650031, China; Southwest Survey and Planning Institute of National Forestry and Grassland Administration, Kunming 650031, China Department of Cardiology, the Fifth People’s Hospital of Shanghai, Fudan University, Shanghai, China Department of Chemical Engineering, Queen’s University, Kingston, Ontario K7L 3N6, Canada Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng, Henan 475004, China Hainan University Sanya Institute of Breeding and Multiplication, National Key Laboratory for Tropical Crop Breeding, , Sanya 572025, China; Hainan University School of Tropical Agriculture and Forestry, , Haikou 570228, China Department of Orthopedics, Fuyang First People's Hospital Department of Chinese and Bilingual Studies, The Hong Kong Polytechnic University , Hong Kong Special Administrative Region [email protected] , [email protected] 4Pathology and; 8Pathology and Southern University of Science and Technology Department of Electrical and Electronic Engineering, , Shenzhen, China [email protected] Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA. [email protected]. Department of Chemical Engineering, Queen’s University, Kingston, Ontario K7L 3N6, Canada; Human Mobility Research Centre, Kingston General Hospital, Kingston, Ontario K7L 2V7, Canada; Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China Department of Nephrology, The First People’s Hospital of Yunnan Province, Kunming, Yunnan, China (mainland) Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy, Wayne State University, 259 Mack Avenue, Detroit, MI, USA Department of Hematology, Zhongnan Hospital of Wuhan University, 169 Dong Hu Road, Wuhan 430071, China Department of Anesthesiology, University of North Carolina at Chapel Hill, NC Laboratory of Pathology Key Laboratory of Transplant Engineering and Immunology NHFPC West China Hospital Sichuan University Chengdu China Materials Genome Institute, Shanghai University, 200444 Shanghai, China Forestry Research Institute, Chengdu Academy of Agricultural and Forestry Sciences, Chengdu 611130, China Max Planck Institute of Polymer Research Ackermannweg 10 55128 Mainz Germany; Institute of Physiological Chemistry and Pathobiochemistry University of Münster Waldeyerstr. 15 48149 Münster Germany 1Institute for Nutritional Sciences, Chinese Academy of Sciences, Shanghai, P. R. China; and; 2The Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, P. R. China Department of Neurology, Xuanwu Hospital Capital Medical University Beijing China Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University Department of Obstetrics and Gynaecology Peking Union Medical College Hospital Beijing China School of Materials and Environmental Engineering, Chengdu Technological University, No. 1, Section 2, Zhongxin Avenue, Pidu District, Chengdu 611730, China The Broad Institute of MIT and Harvard Cambridge Massachusetts Max Planck Institute for Polymer Research Ackermannweg 10 55128 Mainz Germany Biotechnology and Planetary Protection Group, Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California. Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province, Ministry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei 050024, China Department of Cardiology, West China Hospital, Sichuan University , 37 Guoxue Road, Chengdu 610041 , China School of Biology and Basic Medical Science, Agricultural Biotechnology and Ecological Research Institute, Soochow University, Suzhou, 215123, China; Agricultural Biotechnology Research Institute, Agricultural Biotechnology and Ecological Research Institute, Soochow University, Suzhou, 215123, China College of Horticulture Academy for Advanced Interdisciplinary Studies Nanjing Agricultural University Nanjing 210095 China Genetic and Metabolic Central Laboratory, Guangxi Birth Defects Research and Prevention Institute Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region Nanning China; Guangxi Clinical Research Center for Pediatric Diseases, Guangxi Key Laboratory of Reproductive Health and Birth Defects Prevention, Guangxi Key Laboratory of Precision Medicine for Genetic Diseases, Guangxi Key Laboratory of Birth Defects and Stem Cell Biobank, Guangxi Key Laboratory of Birth Defects Research and Prevention Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region Nanning China Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, People’s Republic of China.; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Central South University, Changsha 410013, People’s Republic of China. Department of Pathology, NYU Langone Health, New York, New York *Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505; and Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA Department of Environmental Engineering and Earth Science, Clemson University, Clemson, South Carolina 29634-5002 Department of Otolaryngology, Head and Neck Surgery, West China Hospital, Chengdu 610041, China Hainan Key Laboratory for Sustainable Utilization of Tropical Bioresources, College of Tropical Crops Hainan University Haikou 570228 China; Hainan Yazhou Bay Seed Laboratory, College of Tropical Crops, Sanya Nanfan Research Institute Hainan University Sanya 572025 China Department of Oto‐Rhino‐Laryngology, National Clinical Research Center for Geriatrics, West China Hospital Sichuan University Chengdu China Broad Institute of MIT and Harvard; Harvard University. Laboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS), Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No. 11, First North Road, Zhongguancun, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China Southern University of Science and Technology,Department of Electrical and Electronic Engineering,Shenzhen,China Department of Otorhinolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, PR China. The authors are in the Department of Anesthesiology, University of North Carolina at Chapel Hill in Chapel Hill, NC. is an Assistant Professor; is an Adjunct Associate Professor; , , and are Professors. Department of Neurology, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai, China Laboratory of Pathology West China Hospital, Sichuan University Chengdu China State Key Laboratory of Medicinal Chemical Biology; Tianjin Key Laboratory of Biosensing and Molecular Recognition; College of Chemistry; Nankai University; Tianjin Department of Cardiology, Shanghai Tongji Hospital of Tongji University, Shanghai, PR China Department of Ultrasound, The First Affiliated Hospital of Jinzhou Medical University Jinzhou 121001, Liaoning Province, China. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China College of Life Science & Technology, Xinjiang University, Urumqi 830046, China; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, Urumqi 830046, China Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA PLA General Hospital, Institute of Hepatobiliary Surgery 28 Fuxing Road, Haidian District 100853 Beijing People’s Republic of China Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China Broad Institute of MIT and Harvard, Cambridge, United States Department of Surgery, Jiaxing Second Hospital, Jiaxing, Zhejiang 314000, P.R. China Genetic and Metabolic Central Laboratory Birth Defect Prevention Research Institute, Maternal and Child Health Hospital, Children’s Hospital of Guangxi Zhuang Autonomous Region Nanning China Department of Oncology, The Central Hospital of Xiaogan, Wuhan University of Science and Technology, Xiaogan, China Division of Neonatology and Paediatric Intensive Care, Children's University Hospital of Geneva and University of Geneva, Geneva, Switzerland Department of Child Health-Care, Shanghai Children's Hospital, Shanghai Jiaotong University, Shanghai, China. Biotechnology and Planetary Protection Group, California Institute of Technology, Jet Propulsion Laboratory, Pasadena, California, USA. Orthopedics Department, The First People's Hospital of Yunnan Province, Kunming, Yunnan 650034, P.R. China Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Xueyuan Road 1088#, Xili, Nanshan District, Shenzhen, China [email protected] Division of Speech and Hearing Sciences, The University of Hong Kong , Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong, [email protected] , [email protected] , [email protected]; Hong Kong , Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong, [email protected] , [email protected] , [email protected] Laboratory of Pathology, West China Hospital Sichuan University Chengdu Sichuan China Guangdong Engineering Research centre of Optoelectronic Functional Materials and Devices, Institute of Semiconductors, South China Normal University, Guangzhou, 510631, P. R. China From the Department of Anesthesiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina (S.M.M., R.S.I., F.C.); the Department of Anesthesiology, University of Kentucky College of Medicine, Lexington, Kentucky (R.M.S.); Beth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Boston, Massachusetts, (J.D.M. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Beijing, China. Department of Genetic and Metabolic Central Laboratory, Guangxi Maternal and Child Health Hospital, Nanning, Guangxi 530023, P.R. China School of Mechatronic Engineering, China University of Mining and Technology , No. 1, Daxue Road, Tongshan Zone, Xuzhou, Jiangsu Province 221116, People’s Republic of China Susan M. Martinelli, MD, is Associate Core Program Director and Associate Professor of Anesthesiology, University of North Carolina; Fei Chen, PhD, is Education Research Specialist, University of North Carolina; Amy N. DiLorenzo, MA, is Education Specialist, University of Kentucky; David C. Mayer, MD, is Professor of Anesthesiology, University of North Carolina; Stacy Fairbanks, MD, is Assistant Laboratory of Pathology West China Hospital Sichuan University Chengdu Sichuan China; Key Laboratory of Transplant Engineering and Immunology Ministry of Health West China Hospital Sichuan University Chengdu China Jet Propulsion Laboratory, Pasadena, California, USA. Nanjing Maternity and Child Health Care Institute Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University Nanjing China Hospital of Troop 94587 of Liberation Army of China Lianyungang China Evidence-Based Medicine Center, School of Basic Medical Sciences; Lanzhou University; Lanzhou City China; Evidence-Based Nursing Center, School of Nursing; Lanzhou University; Lanzhou City China Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province Kunming Institute of Zoology The Chinese Academy of Sciences Kunming China Southern University of Science and Technology,Department of Electrical and Electronic Engineering,Shenzhen,China,518055 Harbour BioMed, Shanghai 201203, China Department of Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA. [email protected] Department of Nuclear Medicine, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi, China Departments of Pathology, NYU Langone Health, New York, New York Monroe-Woodbury High School, Central Valley, New York, USA. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, P. R. China Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, China; Department of Electrical and Electronic Engineering, Southern University of Science and Technology of China, Shenzhen, China. Department of Pathology and Laboratory Medicine, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey Neurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA; Howard Hughes Medical Institute, University of California, San Diego, La Jolla, CA 92093, USA Chongqing Key Laboratory of Neurodegenerative Diseases, Yuzhong District, Chongqing 400013, China; Department of Neurology, Chongqing General Hospital, Yuzhong District, Chongqing 400013, China; Chongqing Medical University, Yuzhong District, Chongqing 400016, China Department of Gastroenterology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei Province China; Department of Gastroenterology First Affiliated Hospital of Guizhou Medical University Guiyang Guizhou Province China Department of Neurology Hainan Yazhou Bay Seed Laboratory , Sanya 572024, China; Hainan University College of Tropical Crops, , Haikou 570228, China; Sanya Nanfan Research Institute from Hainan University , Sanya 572025, China for the CASSISS Trial Investigators CAS Key Laboratory of Materials for Energy Conversions; Department of Materials Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology; University of Science and Technology of China; Anhui Hefei 230026; China CAS Key Laboratory of Materials for Energy Conversions, Department of Materials Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Hefei, Anhui 230026, China Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou 730000, China Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China Evidence-Based Nursing Center, School of Nursing; Lanzhou University; Lanzhou China Department of Otorhinolaryngology–Head and Neck Surgery, West China Hospital, West China School of Medicine, Sichuan University, Chengdu School of Foreign Languages, Hunan University, Changsha, Hunan, China Cangxi Plasmapheresis Station, Sichuan Yuanda Shuyang Pharmaceutical Company Limited, Guangyuan, China School of Foreign Languages, Hunan University , Changsha , Hunan , China Department of Obstetrics and Gynecology Key Laboratory for Major Obstetric Diseases of Guangdong Province The Third Affiliated Hospital of Guangzhou Medical University Guangzhou China; Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes The Third Affiliated Hospital of Guangzhou Medical University Guangzhou China State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Agriculture, Nanjing Agricultural University , Nanjing 210095, Jiangsu, China; State Key Laboratory of Cotton Biology, Institute of Cotton Research of CAAS, Anyang 455000 , Henan, China; Taicang Cotton Breeding Center, Taicang , Jiangsu, China i-LAB, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China Department of Cardio-Thoracic Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, P.R. China. Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences (CAS), and University of Chinese Academy of Sciences, Beijing 100190, P. R. China Ministry of Education Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei 050024, China School of Mechatronic Engineering, China University of Mining and Technology , Xuzhou 221116, China CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, No. 11 Beiyitiao, Zhongguancun, Beijing 100190, China Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, P.R. China. Key Laboratory for Space Bioscience and Space Biotechnology; School of Life Sciences; Northwestern Polytechnical University; Xi'an; China State Key Laboratory of Reproductive Medicine Department of Breast Surgery Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University Nanjing 210029 China State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, Taiyuan, China; Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, China College of Chemistry and Materials Science, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Jinan University, Guangzhou 510632, China CAS Key Laboratory of Materials for Energy Conversions, Department of Materials, Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Hefei 230026, Anhui, China Department of Oncology, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology, Xiaogan, Hubei 432000, P.R. China Institute of Stomatology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry Chinese Academy of Sciences (CAS) University of Chinese Academy of Sciences Beijing 100190 P. R. China; Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072 P. R. China Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering School of Life Sciences Fudan University Shanghai China State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, 210095, China grid.9227.e 0000000119573309 Center for Natural Products Research, Chengdu Institute of Biology Chinese Academy of Sciences 610041 Chengdu People’s Republic of China; grid.410726.6 0000000417978419 University of Chinese Academy of Sciences 100049 Beijing People’s Republic of China a Philipps-Universität Marburg, Fachbereich Chemie , Hans-Meerwein Strasse, D-35032 , Marburg , Germany Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen Department of Environmental Engineering & Earth Sciences Clemson University Clemson SC 29634 Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, China Department of Pediatric Surgery, Fujian Province Maternal and Child Health Hospital, Fuzhou, China. Chongqing Key Laboratory of Neurodegenerative Diseases, Chongqing, China; Department of Neurology, Chongqing General Hospital, University of Chinese Academy of Sciences, Chongqing, China Southern University of Science and Technology,Shenzhen Key Laboratory of Robotics Perception and Intelligence,The Department of Electronic and Electrical Engineering,Shenzhen,China,518055 School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin, China *Clinical Research Center, University of Medicine and Dentistry of New Jersey -Robert Wood Johnson Medical School, New Brunswick, NJ 08901; and Departments of *Pathology and Chongqing Hong Fu Cheng Electronic New Materials Co., Ltd, Chongqing 402760, P. R. China 1Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China; Department of Clinical Medicine, Affiliated Hospital of Kunming University of Science and Technology (The First People's Hospital of Yunnan Province), Kunming University of Science and Technology, Kunming, Yunnan 650500, P.R. China Beijing Key Lab of Special Elastomer Composite Materials College of Materials Science and Engineering Beijing Institute of Petrochemical Technology 19 North Qingyuan Road Beijing 102617 P.R. China Department of Emergency Liaocheng People's Hospital Liaocheng China School of Mathematics and Statistics, Guizhou University, Guiyang 550025, China a Foundation for Applied Molecular Evolution , Gainesville, Florida, USA State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Key Laboratory of Genetics, Breeding and Multiple Utilization of Corps, Ministry of Education, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China Southern University of Science and Technology, Shenzhen, China. Rutgers New Jersey Medical School Department of Cell Biology; Second Military Medical University; Shanghai P.R. China; Center for Stem Cell and Medicine, Graduate School; Second Military Medical University; Shanghai P.R. China Department of Spine Surgery, the 2nd Xiangya Hospital of Central South University, Changsha, China Southern University of Science and Technology,Shenzhen Key Laboratory of Robotics Perception and Intelligence,Department of Electrical and Electronic Engineering,Shenzhen,China College of Geomatics, Xi’an University of Science and Technology, Xian, Shaanxi, China Sino-German College of Intelligent Manufacturing, Shenzhen Technology University, Shenzhen 518118, China Beijing Key Laboratory of Genome and Precision Medicine Technologies, Beijing 100101, China. Department of Ultrasound, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, China. Central South University School of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, 550014 Guiyang, P. R. China Department of Medicinal and Organic Chemistry, College of Pharmacy Xinjiang Medical University Urumqi 830011 China School of Materials Science and Engineering; Beijing Institute of Petrochemical Technology; Beijing; China Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany Department of Thyroid Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China. State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO1 Xujiaping, Yanchangbu, Lanzhou 730046, China Department of Electrical and Electronic Engineering Southern University of Science and Technology Shenzhen People's Republic of China The University of North Carolina at Chapel Hill; Chapel Hill North Carolina USA Department of Interventional Neuroradiology, Neurosurgery & Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China (P.G., T.W., J.R., F.C., L.J.). The Affiliated Tengzhou Hospital of Xuzhou Medical University, Tengzhou, Shandong Province, China Department of Gynecology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Science Beijing China Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, 48149 Münster, Germany Shanghai University, China West China School of Public Health, Sichuan University, Chengdu, China Research Centre for Language, Cognition, and Neuroscience, Department of Chinese and Bilingual Studies, The Hong Kong Polytechnic University, Hong Kong SAR, China Department of Ultrasound, The First Affiliated Hospital of Jinzhou Medical University, Gu Ta district, Jinzhou, Liao Ning province 121001, China. Departments of Clinical Nutrition, the Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China. The CAS Key Laboratory of Genome Sciences and Information; Beijing Institute of Genomics, Chinese Academy of Sciences; Beijing 100101 China Division of Speech and Hearing Sciences, The University of Hong Kong, Prince Philip Dental Hospital , 34 Hospital Road, Hong Kong [email protected] , [email protected] Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Shenzhen, China [email protected] , [email protected] College of Life Science and Technology; Xinjiang University; Urumqi 130046; China CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China College of Horticulture Nanjing Agricultural University Nanjing China Particulate Fluids Processing Centre, School of Chemistry, University of Melbourne, VIC 3010, Australia, and Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA CAS Key Laboratory of Materials for Energy Conversions, Department of Materials Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Anhui Hefei 230026, China Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China. MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Department of Cardiology, West China Hospital, Sichuan University Storr Liver Centre,Westmead Institute for Medical Research, Westmead Hospital and University of Sydney,Westmead,NSW,Australia Department of Gastroenterology the Second Affiliated Hospital of Shandong First Medical University Taian China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China Fei Chen, PhD, MEd, is Assistant Professor of Anesthesiology, University of North Carolina School of Medicine Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505; and College of Environmental Science and Engineering, and ‡Key Laboratory of Environmental Biology and Pollution Control, Ministry of Education, Hunan University, Changsha 410082, People’s Republic of China Key Laboratory of Tissue Engineering of Shenzhen The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital Shenzhen China Service de Génétique Médicale, Centre Hospitalier Universitaire Vaudois, CH-1011 Lausanne, Switzerland.; Brain Mind Institute, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland. German Research Center for Artificial Intelligence (DFKI) , 66123 Saarbrücken, Germany State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000 P. R. China Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province College of Life Sciences Hebei Normal University Shijiazhuang China School of Chemistry and Chemical Engineering/State Key Laboratory Incubation Base for Green Processing of Chemical Engineering, Shihezi University, North 4th Road, Shihezi, Xinjiang 832003, China Department of Gastroenterology, Changzheng Hospital Second Military Medical University Shanghai PR China Storr Liver Centre,Westmead Institute for Medical Research,Westmead Hospital and University of Sydney,Westmead,New South Wales,Australia Beijing National Laboratory for Molecular Sciences (BNLMS) CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry, Chinese Academy of Sciences (CAS) University of Chinese Academy of Sciences Beijing 100190 P.R. China; Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072 P.R. China School of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550002, China; Dazhou Integrated, TCM&Western Medicine Hospital, Dazhou 635000, China Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China College of New Materials and Chemical Engineering, Beijing Key Lab of Special Elastomeric Composite Materials, Beijing Institute of Petrochemical Technology, Beijing 102617, China Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China. Department of Surgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang P.R. China Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry and Graduate School, Chinese Academy of Sciences (CAS), Beijing 100190, P. R. China State Key Laboratory of Optoelectronic Materials and Technologies; School of Physics & Engineering; Sun Yat-sen University; Guangzhou 510275, P. R. China Department of Orthopedics II, The First People's Hospital of Fuyang District, Zhejiang, China. The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology and Chongqing Eye Institute, Chongqing, China *Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611; Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, People's Republic of China; Department of Electrical and Electronic Engineering Southern University of Science and Technology Shenzhen People’s Republic of China School of Chemical Engineering and Technology Xi'an Jiaotong University Xi'an 710049 P. R. China Key Laboratory for Special Functional Materials of Ministry of Education National & Local Joint Engineering Research Center for High‐Efficiency Display and Lighting Technology School of Materials Henan University Kaifeng 475004 China Materials Genome Institute, Shanghai University; Shanghai 200444; China Department of Ultrasonics, The First Hospital of Jinzhou Medical UniversityJinzhou 121000, China. Department of Gastroenterology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Institute of Gastroenterology, Zhejiang University, Hangzhou 310009, China. Peking Union Medical College Hospital, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, China Stony Brook Cancer Center, and Department of Pathology, Stony Brook University, Stony Brook, NY, USA. School of Chemical Engineering and Technology, Xi’an Jiaotong University, Xi’an, 710049, P. R. China Physical Education Institute, Southwest Forestry University, Kunming 650224, China Department of Obstetrics and Gynecology Peking Union Medical College Hospital Beijing China Service de psychiatrie pour enfants et adolescents (SPEA), Secteur psychiatrique Nord (SPN), Département de psychiatrie, Centre hospitalier universitaire vaudois (CHUV), Yverdon-les-Bains, Switzerland. School of Chemistry and Chemical Engineering/State Key Laboratory Incubation Base for Green Processing of Chemical Engineering, Shihezi University, North fourth Road, Shihezi, Xinjiang 832003, China CAS Key Laboratory of Materials for Energy Conversions; Department of Materials Science and Engineering; Collaborative Innovation Center of Suzhou Nano Scienceand Technology; University of Science and Technology of China; Hefei 230026 Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi Jiangsu 214063 China School of Chemistry and Chemical Engineering Hefei University of Technology Anhui Key Laboratory of Controllable Chemical Reaction & Material Chemical Engineering Hefei Anhui 230009 P.R. China Department of Pediatric Orthopaedics and Department of Radiology Tianjin Hospital, Tianjin University Tianjin 300211 China Department of Breast Surgery, Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China *Division of Biology, California Institute of Technology, Pasadena, CA 91125; and CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China Southern University of Science and Technology Department of Electrical and Electronic Engineering, , Shenzhen, China [email protected] , [email protected] Department of Otolaryngology-Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610064, China; Head and Neck Surgical Center, West China Hospital, Sichuan University, Chengdu 610064, China School of Foreign Languages, Hunan University, Hunan, China From the Department of Pathology and Laboratory Medicine, UMDNJ–New Jersey Medical School, Newark. School of Automobile and Transportation, Xihua University, Chengdu, Sichuan Province, China; Provincial Engineering Research Center for New Energy Vehicle Intelligent Control and Simulation Test Technology of Sichuan, Xihua University, Chendu, Sichuan Province, China; Vehicle Measurement, Control and Safety Key Laboratory of Sichuan Province, Xihua University, Chendu, Sichuan Province, China College of Computer and Data Science Fuzhou University Fuzhou Fujian China Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, 518055, China Department of Spine Surgery, The Second Xiangya Hospital of Central South University, No.139, Renmin Middle Road, Changsha 410011, China Email:[email protected]. Department of Ultrasound The Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai China Department of Anesthesiology, Mindong Hospital Affiliated to Fujian Medical University, Ningde, Fujian 355000, P.R. China Keck School of Medicine, University of Southern California, Los Angeles College of Tropical Crops, Hainan University , Haikou 570228 , China Authors' Affiliations: 1Graduate Center for Toxicology, University of Kentucky, Lexington, Kentucky and 2The Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia Department of Cardiology, West China Hospital Sichuan University Chengdu China Department of Radiation Oncology, Affiliated Hospital of Jiangsu University, Zhenjiang 212000, China Department of Laboratory Medicine, Huadong Hospital affiliated to Fudan University, No. 221 Yanan West Road, Shanghai 200040, China Department of Epidemiology and Health Statistics, West China School of Public Health, Sichuan University, Chengdu Sichuan, China Department of Radiation Oncology Fujian Medical University Cancer Hospital, Fujian Cancer Hospital Fuzhou Fujian China Janssen Research & Development Johnson & Johnson 920 Rt 202 S. Raritan NJ 08869 U.S.A. Department of Cardiology, The Second Hospital of Hebei Medical University and The Institute of Cardiocerebrovascular Disease of Hebei Province, Shijiazhuang 050000, China Department of Andrology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing Evidence‐Based Nursing Center, School of Nursing Lanzhou University Lanzhou China; Evidence‐Based Medicine Center, School of Basic Medical Sciences Lanzhou University Lanzhou China CCDC Chuangqing Downhole Technology Company, Xi’an 710018, China National Laboratory of Solid State Microstructures and School of Physics, and Collaborative InnovationCenter of Advanced Microstructures Nanjing University Nanjing 210093 P. R. China Institute of Life Sciences Fuzhou University Fuzhou Fujian China 1Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, Maryland. Institute for Advanced Materials, Jiangsu University, Zhenjiang 212013, China Division of Speech and Hearing Sciences, The University of Hong Kong, Prince Philip Dental Hospital , 34 Hospital Road, Hong Kong [email protected] Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, 48149 Münster, Germany Engineering Research Centre of Utilization of Tropical Polysaccharide Resources of MOE, School of Food Science and Engineering Hainan University Haikou China Department of Hematology The Zhongnan Hospital Wuhan University Wuhan China Institute of Hepatobiliary Surgery Chinese PLA General Hospital Beijing China College of Life and Environmental Sciences Hangzhou Normal University Hangzhou China CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences (ICCAS), Beijing 100190, P. R. China School of Pharmacy, Second Military Medical University, Shanghai,China Department of Ultrasound Second Affiliated Hospital of Guangzhou Medical University Guangzhou China CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences (CAS), University of Chinese Academy of Sciences, Beijing 100190, P. R. China Institute of Cardiology, First Affiliated Hospital, Zhejiang University Medical College, Hangzhou, China; and Key Lab of Training, Monitoring and Intervention of Aquatic Sports of General Administration of Sport of China, Institute of Physical Education, Jiangxi Normal University, Nanchang, China Department of Gastroenterology Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang Province China; Institute of Gastroenterology Zhejiang University Hangzhou Zhejiang Province China Department of Obstetrics and Gynecology Peking University First Hospital Beijing China School of Transportation, Southeast University, Nanjing, China State Key Laboratory of Laser Interaction with Matter; Changchun Institute of Optics, Fine Mechanics and Physics; Chinese Academy of Sciences; Changchun; China Department of Pediatric Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China; CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, 11 Beiyitiao, Zhongguancun, Beijing 100190, China Department of Obstetrics and Gynecology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 Key Laboratory of Training Monitoring and Intervention of Aquatic Sports of General Administration of Sport of China, Institute of Physical Education, Jiangxi Normal University, Nanchang, China Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM); National Jiangsu Synergistic Innovation Center for Advanced Materials; Nanjing Tech University; Nanjing 211816; China Institute of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing, China. Nanjing University of Chinese Medicine, Nangjing 210046, China. [email protected] Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, College of Veterinary MedicineChina Agricultural University, Beijing 100193, China Department of Nuclear Medicine; Nanjing Medical University; Affiliated Wuxi People's Hospital; Wuxi; China Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat‐Sen Memorial Hospital Sun Yat‐Sen University Guangzhou China; Breast Tumor Center, Sun Yat‐Sen Memorial Hospital Sun Yat‐Sen University Guangzhou China Southern University of Science and Technology Department of Electrical and Electronic Engineering, , Xueyuan Road 1088#, Xili, Nanshan District, Shenzhen 518055, China State Key Laboratory of Laser Interaction with Matter, Changchun Institute of Optic, Fine Mechanic and Physics, Chinese Academy of Sciences 1 , Changchun 130033, China; Innovation Laboratory of Electro-Optical Countermeasures Technology, Changchun Institute of Optic, Fine Mechanic and Physics, Chinese Academy of Sciences 2 , Changchun 130033, China Key Lab for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun City, Jilin Province, 130023, P. R. China Chinese Academy of Sciences Children’s Research Institute, University of Texas Southwestern Medical Center, Dallas, United States; Departments of Neuroscience, University of Texas Southwestern Medical Center, Dallas, United States; Departments of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, United States Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan 430071, China, Graduate Center for Toxicology and Department of Medicine, University of Kentucky, 234 Health Science Research Building, Lexington, Kentucky 40536, and Laboratory of Cancer Signaling and Epigenetics, Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, West Virginia 26505 Lab of Pathology, Key Lab of Transplantation Engineering and Immunology, Ministry of Health, Precision Medicine Key Laboratory of Sichuan Province West China Hospital, Sichuan University Chengdu Sichuan Province China Institution of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Xueyuan Road 1088#, Xili, Nanshan District, Shenzhen, China [email protected] , [email protected] Department of Cardiology, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P. R. China Department of Oto-Rhino-Laryngology, and National Clinical Research Center for Geriatrics, West China Hospital, West China Medical School, Sichuan University Department of Clinical Nutrition Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. [email protected] Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455 The Second Department of Orthopedics, Hangzhou Fuyang District First People’s Hospital, Hangzhou, PR China College of Life Science and Technology, Xinjiang University, Urumqi 130046, China State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China Anesthesiology College of Food Science and Technology Hunan Agricultural University Changsha China Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Shenzhen, China [email protected] Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, 30 South Puzhu Road, Nanjing 211816, P. R. China School of Chemistry and Chemical Engineering/State Key Laboratory Incubation Base for Green Processing of Chemical Engineering, Shihezi University, North Fourth Road, Shihezi, Xinjiang 832003, China School of Foreign Languages, Hunan University 2 , Changsha, China School of Chemical Engineering and Technology; Xi'an Jiaotong University; Xi'an 710049; China; Smart Materials and Surfaces Laboratory Department of Applied Physics, The Hong Kong Polytechnic University, Hong Kong, China Zhongnan hospital of Wuhan University, Wuhan, China Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany Department of Ultrasound, The First Affiliated Hospital of Jinzhou Medical UniversityJinzhou, Liaoning Province, China. School of Chemistry and Chemical Engineering, Anhui Key Laboratory of Controllable Chemical Reaction & Material Chemical Engineering, Hefei University of Technology, Hefei, Anhui 230009, People’s Republic of China State Key Lab of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 China Author's Affiliation: Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan Department of Cardiology, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China. Beijing National Laboratory for Molecular Sciences; CAS Key Laboratory of Molecular Recognition and Function; Institute of Chemistry; Chinese Academy of Sciences (CAS); and University of Chinese Academy of Sciences a National Institute for Occupational Safety and Health, Health Effects Laboratory Division, and Department of Physiology and Pharmacology, West Virginia University, Morgantown, West Virginia, USA Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding, State Key Laboratory of Hybrid Rice, Jiangsu Key Laboratory of Crop Genetics and Physiology, Yangzhou University, Yangzhou 225009, China Department of Applied Chemistry, School of Engineering, University of Toyama, Gofuku 3190, Toyama 930-8555, Japan CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China Department of Ultrasound, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, PR China Department of Health Service, The Second Mobile Corps Hospital of Chinese People's Armed Police Force, Wuxi, Jiangsu 214000, P.R. China Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering School of Life Sciences Fudan University 2005 Songhu Road Shanghai 200438 China Spine Surgery Department, Second Xiang-Ya Hospital of Central South University, Changsha, Hunan 410011, China PPRB, NIOSH, Morgantown, WV 26505. State Key Laboratory on Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730030, China The second Department of Chest Radiation, Shanxi Cancer Hospital, Taiyuan City, Shanxi Province, China Reconstructive Pelvic Surgery, Departments of Obstetrics and Gynecology, the Third Affiliated Hospital of Zhengzhou University Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education), School of Materials Science and Engineering, Northeastern University, Shenyang, 110819, China Center for Stem Cell Biology and Tissue Engineering, Sun Yat-sen University, Guangzhou 510085, Guangdong Province, China. Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, Hebei, China Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing Tech University 30 South Puzhu Road Nanjing 211816 P.R. China Department of Child Health Care Qilu Children's Hospital of Shandong University Jinan Shandong China Department of Gastroenterology; Changzheng Hospital, Second Military Medical University; Shanghai China Department of Digestive Center, Tiantai Branch of Zhejiang Provincial Peoples' Hospital, Taizhou, Zhejiang 317200, P.R. China Chinese Academy of Sciences Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics; University of Chinese Academy of Sciences; Collaborative Innovation Center for Genetics and Development, Shanghai, China School of Computer Science and Engineering, Southeast University, Nanjing 211189, China; MOE Key Laboratory of Computer Network and Information Integration, Southeast University, Nanjing 211189, China Department of Medical Ultrasound The Second Affiliated Hospital of Guangzhou Medical University Guangzhou China CAS Key Laboratory of Materials for Energy Conversions, Department of Materials Science and Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China, Anhui Hefei, 230026, China From the Genetic and Metabolic Central Laboratory (Sheng Yi, F.C., Z.Q., Shang Yi, Limei Huang, H.W., Q.Y., Q.Z., J.L.), Guangxi Birth Defects Research and Prevention Institute, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region; Guangxi Key Laboratory of Reproductive Health and Birth Defects Prevention (Sheng Yi, F.C., Z.Q., Shang Yi, Limei Huang, H.W., Q.Y., Q.Z., J.L.), Guangxi Key Laboratory of Precision Medicine for Genetic Diseases, Guangxi Key Laboratory of Birth Defects... CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China; Collaborative Innovation Center for Genetics and Development, Shanghai, China The State Key Laboratory of Medical Genetics and School of Life Sciences, Central South University, Changsha, China People’s Liberation Army Troop 94587, Lianyungang, 222300, China Department of Respiratory The Foundation for Applied Molecular Evolution (FfAME), 13709 Progress Blvd., Box 17, Alachua, Florida 32615, United States State Key Laboratory of Cellular Stress Biology Innovation Center for Cell Signaling Network School of Life Sciences Xiamen University Xiamen Fujian 361102 China Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai’an City 271018, P. R. China Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA Department of Clinical Laboratory, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, China School of Mechatronic Engineering, China University of Mining and Technology, Xuzhou 221116, China School of Automobile and Transportation, Xihua University, Chengdu, Sichuan Province, China; Vehicle Measurement, Control and Safety Key Laboratory of Sichuan Province, Xihua University, Chengdu, China; Provincial Engineering Research Center for New Energy Vehicle Intelligent Control and Simulation Test Technology of Sichuan, Xihua University, Chengdu, China Department of Cardiology, West China Hospital Sichuan University Chengdu PR China CAS Key Laboratory of Genome Sciences & Information, Beijing Institute of Genomics Chinese Academy of Sciences, China National Center for Bioinformation Beijing China College of Life Sciences University of Chinese Academy of Sciences Beijing China East China Normal University Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, USA; Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, USA CAS Key Laboratory of Precision and Intelligent Chemistry, Department of Materials Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China Department of Neurology, Beijing Military 254 Hospital, Tianjin, China (mainland) School of Chemistry and Chemical Engineering/State Key Laboratory Incubation Base for Green Processing of Chemical Engineering Shihezi University North Fourth Road Shihezi Xinjiang 832003 China Department of Cell Biology, Second Military Medical University, Shanghai, P.R. China; Center for Stem Cell and Medicine, The Graduate School, Second Military Medical University, Shanghai, P.R. China School of Chemistry and Chemical Engineering, Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, North Fourth Road, Shihezi, Xinjiang 832003, People’s Republic of China Microbial Research Institute of Liaoning Province, Chaoyang, Liaoning, China, ; Department of Cardiology West China Hospital Sichuan University Chengdu China Graduate School, Kunming Medical University, Kunming, Yunnan 650500, P.R. China Department of Media Arts and Sciences, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Department of Spine Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China. School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, China; Laboratory of Pathology, Department of Pathology, West China Hospital Sichuan University, Chengdu, P.R. China Department of Pathology, Department of Population Health, NYU Langone Health, New York, NY Department of Neurosurgery, The Sixth People's Hospital of Nantong Nantong 226011, Jiangsu Province, China. Department of Neurology, Beijing Haidian Hospital, Beijing, China Department of Cardiology Tongji Hospital, Tongji University School of Medicine Shanghai China Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. People's Hospital of Xinjiang Uygur Autonomous Region Urumqi China The Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia College of Horticulture, Nanjing Agricultural University, Nanjing, China State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China McGowan Institute for Regenerative Medicine and Department of Pathology,University of Pittsburgh School of Medicine,Pittsburgh,Pennsylvania,USA; Department of Histology and Embryology,School of Basic Sciences,Guangzhou Medical University,Guangzhou,China Department of Anaesthesiology; University of North Carolina at Chapel Hill; Chapel Hill North Carolina USA Ningbo Institute of NPU Northwestern Polytechnical University Ningbo 315000 P. R. China Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China Department of Nutrition, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang 310052, China Key Laboratory for Anisotropy and Texture of Materials (Ministry of Education), School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505; and Howard Hughes Medical Institute and Department of Cell Biology and Physiology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8228, St. Louis, MO 63110-1093 Translational Medicine Institute National and Local Joint Engineering Laboratory for High‐throughput Molecular Diagnosis Technology, Affiliated The First People's Hospital of Chenzhou, University of South China Chenzhou China; The Fourth People's Hospital of Changde Hunan province China Department of Neurology, 254 Hospital Tianjin, China. Department of Chinese and Bilingual Studies, Research Centre for Language, Cognition, and Neuroscience, The Hong Kong Polytechnic University, Hong Kong SAR, China Evidence-Based Medicine Center, School of Basic Medical Sciences, Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou 730000, P.R. China Department of Oral Implants, School of Stomatology, State Key Laboratory of Military Stomatology The Fourth Military Medical University Xi'an China Key Lab for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, 130023, P.R. China. Genetic and Metabolic Central Laboratory Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region Nanning China Department of Electrical and Electronic Engineering, Southern University of Science and Technology , Shenzhen, China [email protected] College of Science; University of Shanghai for Science and Technology; 200093 Shanghai; China Genetic and Metabolic Central Laboratory, Birth Defects Prevention and Control Institute of Guangxi Zhuang Autonomous Region, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region , Nanning 530003 , China Department of Nuclear Medicine, The Affiliated Hospital of North Sichuan Medical College Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, People's Republic of China, and Department of Chemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People's Republic of China State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China Department of Ultrasound Xinqiao Hospital, Army Medical University Chongqing China Chinese Academy of Sciences (CAS), Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No. 11, First North Road, Zhongguancun, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China Department of Neurology Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University Nanjing China State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000 P. R. China Broad Institute of Harvard and MIT, Boston, Massachusetts 02142, USA; Guangxi Health Commission Key Laboratory of Precise Diagnosis and Treatment of Genetic Diseases Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region Nanning China; Genetic and Metabolic Central Laboratory Guangxi Birth Defects Research and Prevention Institute Nanning China Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, West Virginia 26506, and Nelson Institute of Environmental Medicine, New York University School of Medicine, New York, New York 10016 School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China; State Key Laboratory of Luminescent Materials and Devices, and Institute of Optical Communication Materials, South China University of Technology, Guangzhou 510641, China Department of Orthopedics, Changzheng Hospital, The Second Military Medical University, Shanghai, People's Republic of China College of Life Sciences, University of the Chinese Academy of Sciences , Beijing 10140 , China Institute of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry and Graduate School, Chinese Academy of Sciences (CAS), Beijing 100190, P. R. China, and Department of Chemistry, Renmin University of China, Beijing 100972, P. R. China Department of Biochemistry Zhongshan School of Medicine Sun Yat‐sen University Guangzhou China State Key Laboratory of Optoelectronic Materials and Technologies; School of Physics & Engineering; Sun Yat-sen University; Guangzhou 510275; P. R. China Department of Epidemiology, Bloomberg School of Public Health, and Department of Applied Physics; Donghua University; Shanghai 201620; P. R. China Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505; and State Key Laboratory of Laser Interaction with Matter; Innovation Laboratory of Electro-Optical Countermeasures Technology; Changchun Institute of Optics; Fine Mechanics and Physics; Chinese Academy of Sciences Chinese National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, 189 Guoshoujing Road, Shanghai, 201203, China Department of Geratology, Chongqing Mental Health Center, Chongqing, China Department of Neurology The Deqing People's Hospital Huzhou Zhejiang China Department of Orthopaedics Second Affiliated Hospital of Naval Medical University Shanghai China Teaching and Research Section, Nanjing Medical University, Nanjing 210029, China. |
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