http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_8cacf79e089c0a3fab2a8f2f884a64f8
Outgoing Links
Predicate | Object |
---|---|
family-name | Hua Wang Wang |
name | Hua Wang Hua. Wang |
given-name | Hua Hua. |
organization-name | Department of Orthopaedics, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 211100, China Key Laboratory for Special Functional Materials of Ministry of Education Henan University Kaifeng 475004 People's Republic of China; College of Chemistry and Chemical Engineering Henan University Kaifeng 475004 People's Republic of China Department of Neonatology, West China Second Hospital, Sichuan University, Chengdu, Sichuan 610041, China School of Pharmaceutical Sciences, Peking University Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, and Hope Heart Program, Benaroya Research Institute at Virginia Mason, Seattle, Washington 98101 Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, PR China.; Beijing Key Laboratory for Radiobiology, Beijing, PR China. College of Acupuncture and Orthopedics, Hubei University of CM, Wuhan 430061, China. Department of Electrical Engineering and Computer Science, Colorado School of Mines, Golden, Colorado. Hebei Medical University 361 East Zhongshan Road Shijiazhuang 050017 Hebei China Key Laboratory of Colloid and Interface Science, Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Institute for Liver Disease of Anhui Medical University, Hefei, Anhui, People’s Republic of China Stanley Ho Centre for Emerging Infectious Diseases The Chinese University of Hong Kong Hong Kong P. R. China Department of Computer Science, Colorado School of Mines , Golden, CO 80401, USA College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China Key Laboratory of Material Chemistry for Energy Conversion and Storage of Ministry of Education (HUST), and State Key Laboratory of Materials Processing and Mold Technology; School of Chemistry and Chemical Engineering; Huazhong University of Science and Technology (HUST); Wuhan 430074; China School of Civil Engineering and Architecture, Zhejiang University of Science and Technology, Hangzhou 310023, China The Key Laboratory of Functional Molecular Solids, Ministry of Education, School of Chemistry and Materials Science, Anhui Normal University, Wuhu241002, China Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390–9148, USA. Department of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan, China Department of Endocrinology, East Hospital Tongji University School of Medicine Shanghai China Hubei University of CM, Wuhan 430061, China. College of Enology, Northwest A&F University, Yangling, China; China Wine Industry Technology Institute, Yinchuan, China; Shaanxi Engineering Research Center for Viti-Viniculture, Yangling, China Department of Pediatrics, Second Clinical College, China Medical University, Shenyang 110004, China. [email protected] 1Radiation Oncology and Departments of Department of Basic Science of Stomatology, Affiliated Hospital of Stomatology Nanjing Medical University Nanjing China; Jiangsu Key Laboratory of Oral Diseases Nanjing Medical University Nanjing China; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing China University of Chinese Academy of Sciences, Beijing 100049, P.R. China Department of Endocrinology, Jiangyin Hospital of Traditional Chinese Medicine, Jiangyin, China. Department of Electronic Information Engineering, Rizhao Polytechnic, Rizhao 276826, China The Affiliated Hospital of Jiangsu University, Zhenjiang, China. Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China; Women and Children's Hospital of Hunan Province Changsha Hunan China Department of Ultrasonic Luoyang Central Hospital Affiliated to Zhengzhou University Luoyang China Anhui Chest Hospital (Anhui Provincial TB Institute) Hefei China Department of Laboratory Medicine Ren Ji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Shandong Province Key Laboratory of Life-Organic Analysis; School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu City, P. R. China Key Laboratory for Green Chemical Technology of the Ministry of Education, School of Chemical Engineering and Technology, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin University, Tianjin 300072, P. R. China Jiangsu Key Laboratory of Oral Diseases Nanjing Medical University Nanjing PR China; Department of Basic Science of Stomatology Affiliated Hospital of Stomatology, Nanjing Medical University Nanjing PR China Beijing Key Laboratory for Radiobiology, Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation Medicine, Beijing 100850, China College of Enology, Northwest A&F University, Shaanxi, Yangling 712100, China College of Chemistry and Materials Science; Sichuan Normal University; Chengdu 610066; China State Key Laboratory of Material Processing and Die & Mold Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China Bridge Engineering Research Institute, Guangxi Transportation Science and Technology Group Co., Ltd., Nanning 530007, China Department of Endocrinology Shanghai East Hospital Tongji University School of Medicine Shanghai China Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming 650093, PR China Neonatal Intensive Care Units Women's Hospital School of Medicine Zhejiang University Hangzhou Zhejiang China Jiangxi Key Laboratory of Clinical and Translational Cancer Research, Department of Oncology, The Second Affiliated Hospital of Nanchang University, Nanchang City, China.; Department of Oncology, The Second Affiliated Hospital of Nanchang University, Nanchang City, China. Department of Ophthalmology, Air Force General Hospital, Beijing 100089, P.R. China Department of Food Science and Nutrition, University of Minnesota, St. Paul, Minnesota 55108,1 and College of Enology Northwest A & F University Yangling China; Shaanxi Engineering Research Center for Viti‐Viniculture Yangling China Sorrento Therapeutics, Inc. , San Diego, CA 92121 , USA Department of Chemistry, Washington State University, Pullman, Washington 99164, United States College of Food Science and Engineering, College of Enology, Northwest Agriculture and Forestry University, Yangling 712100, China. [email protected] Institute of Molecular Medicine, Department of Gastrointestinal Surgery, Clinical Laboratory, Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of Urology, the First Affiliated Hospital, Zhejiang University Medical College, Hangzhou, Zhejiang 310003, China. [email protected] School of Mechanical Engineering, Shanghai Jiao Tong University, Dongchuan Road 800, Shanghai 200240, China Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health; Bethesda; MD State Key Laboratory of Pollution Control and Resources Reuse, Tongji University, Shanghai 200092, China. [email protected] Engineering Research Center for Nanomaterials Henan University Kaifeng 475004 P. R. China Guangdong Climate Center, Guangzhou 510080, China. Key Lab of Organic Optoelectronics and Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, People’s Republic of China From the Departments of Pathology (Drs S. Shroff, Rashid, and Huamin Wang), Gastrointestinal Medical Oncology (Drs Overman, R. T. Shroff, Hua Wang, Wolff, and Abbruzzese), and Surgical Oncology (Drs Chatterjee, Katz, Lee, and Fleming). The University of Texas M. D. Anderson Cancer Center, Houston. Division of Rheumatology and Immunology, Department of Medicine, University of Southern California School of Medicine, 2011 Zonal Avenue, HMR711, Los Angeles, CA 90033, USA The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China. Department of Orthopedics,The Affiliated Jiangning Hospital of Nanjing Medical University,Nanjing 211100,China. The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong China School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine Chinese Academy of Medical Sciences Beijing China Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China Key Laboratory of Materials Physics; Anhui Key Laboratory of Nanomaterials and Nanotechnology; Institute of Solid State Physics; Chinese Academy of Sciences; Hefei 230031 Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Medical University, Hefei, China Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China and Shimadzu Research Laboratory (Shanghai) Company, Ltd., Shanghai 201201, China Department of Computer Science and Engineering, University of Texas at Arlington, Arlington, Texas. Engineering Research Center for Nanomaterials, Henan University, Kaifeng, 475004, China Prenatal Diagnosis Center of Hunan Province, Hunan Maternal and Child Health Hospital, Changsha, Hunan 410008, P R China. [email protected] Authors' Affiliations: 1Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and 2Department of Dermatology, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts Key Laboratory of Colloid and Interface Science, Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China Department of Materials Science and Engineering, University of Illinois at Urbana−Champaign, Urbana, Illinois 61801, United States Department of Hematology, Hainan General Hospital, Haikou, Hainan, 570311, P.R. China Department of Oncology, the First Affiliated Hospital, Institute for Liver Diseases of Anhui Medical UniversityHefeiChina State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States College of Environmental and Energy Engineering, Anhui Jianzhu University, Hefei 230601, China; Anhui Key Laboratory of Environmental Pollution Control and Waste Resource Utilization, Anhui Jianzhu University, Hefei 230601, China College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Wuhan 430070, China Department of Pathology, Affiliated Hospital of Nantong University, Nantong, China Department of Oncology The First Affiliated Hospital of Anhui Medical University Hefei Anhui 230022 China; School of Pharmacy Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Anhui Medical University Hefei Anhui 230032 China Laboratory of General Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China Department of Medical Genetics, Maternal and Children Health Hospital of Hunan, Changsha 410008, Hunan Province, China,E-mail: [email protected]. Key Laboratory of Interface Science and Engineering in Advanced Materials of Ministry of Education and Research Center of Advanced Materials Science and Technology Taiyuan University of Technology No. 79, Yingze West Street Taiyuan 030024 P.R. China Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of the Ministry of Education, School of Chemistry and Environment, Beihang University, Beijing 100191, PR China Key Laboratory of Materials Physics; Anhui Key Laboratory of Nanomaterials and Nanostructures; Institute of Solid State Physics; Chinese Academy of Sciences; Hefei 230031 Department of Chemical Physiology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla CA 92037 USA; Department of Chemistry The Scripps Research Institute 10550 North Torrey Pines Road La Jolla CA 92037 USA Unité Mixte de Recherche 990 Institut National de la Recherche Agronomique/Institut National Polytechnique–Ecole Nationale Supérieure Agronomique Toulouse Génomique et Biotechnologie des Fruits Pôle de Biotechnologie Végétale 31326 Castanet-Tolosan Cedex France Department of Pharmacy, Taian Central Hospital Taian 271000, China. The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine; School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu 273165; China Department of General Surgery of Integrative Chinese and Western Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai. Institute of Plant Protection and Soil Fertilizer, Hubei Academy of Agricultural Sciences/Key Laboratory of Integrated Pest Management on Crops in Central China, Ministry of Agriculture/Hubei Key Laboratory of Crop Disease, Insect Pests and Weeds Control, Wuhan, Hubei, P.R. China Department of Gastroenterology, Xi'an Children's Hospital, Xi'an, Shaanxi, China; Medical College Jiangsu University Zhenjiang P.R. China Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, China. Department of Materials Science and Engineering, Texas A&M University, College Station, Texas 77843, United States Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA 5School of Biomedical Science, The Chinese University of Hong Kong, Hong Kong, China. Department of Orthopedics Clinical Medical College of Yangzhou University Yangzhou China; Department of Orthopedics Northern Jiangsu People’s Hospital Yangzhou China Department of Hematology, Yantai Yuhuangding Hospital, Yantai, Shandong Province, China. College of Enology, Shaanxi Engineering Research Center for Viti‐Viniculture Northwest A&F Univ. Yangling China Department of Chemistry, Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois 60208-3113, United States Department of Orthodontics The Affiliated Stomatological Hospital of Nanjing Medical University Nanjing China; Jiangsu Province Key Laboratory of Oral Diseases Nanjing China; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing China 2Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Anesthesiology, TISCO General Hospital, Taiyuan, Shanxi, 030000, China School of Electrical, Computer, and Energy Engineering, Arizona State University, Tempe, Arizona, United States Key Laboratory of Materials Physics, Anhui Key Laboratory of Nanomaterials and Nanotechnology Institute of Solid State Physics, Chinese Academy of Sciences, University of Science and Technology of China Hefei P. R. China Department of Medical Genetics National Health Commission Key Laboratory of Birth Defects Research Hunan Provincial Maternal and Child Health Care Hospital Changsha China Department of Food Science and Technology; The Ohio State University; Columbus; USA; Department of Microbiology School of Chemistry and Chemical Engineering, Jiangsu Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing 211189, PR China National Health Commission Key Laboratory for Birth Defect Research and Prevention, Hunan Provincial Maternal and Child Health Care Hospital , Changsha, Hunan 410008, China; Department of Medical Genetics, Maternal and Child Health Hospital of Hunan Province , Changsha, Hunan 410008, China Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China Department of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming 650093, China Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu City, Shandong Province 273165, P. R. China Institute of Forestry and Pomology Beijing Academy of Agriculture and Forestry Sciences Beijing China; Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) Ministry of Agriculture Beijing China Department of Spine Surgery The First Affiliated Hospital Sun Yat‐sen University 58, Zhongshan 2nd Road 510080 Guangzhou China The Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong, Jiangsu 226000, P.R. China Department of Oncology The First Affiliated Hospital of Anhui Medical University Hefei 230022 China Department of Pharmacology, College of Pharmaceutical Sciences, Beihua University, Jilin, China. Department of Health Outcomes and Policy, University of Florida, Gainesville, Florida. 1 Department of Computer Science and Engineering, University of Texas at Arlington, Arlington, TX 76019, USA 2Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 950 W. Walnut St, R2 E124F, Indianapolis, IN 46202, USA College of Enology, Northwest A&F University, Xianyang 712100, China Key Laboratory of Interface Science and Engineering in Advanced Materials Ministry of Education Taiyuan University of Technology 030024 Taiyuan P. R. China Stanley Ho Centre for Emerging Infectious Diseases, Third Military Medical University, Chongqing, 400038, P. R. China Department of Orthopedics, The First Affiliated Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510080, P.R.�China Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China. Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China Department of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China Department of Electronic Science and Technology, Huazhong University of Science and Technology, 430074, Wuhan, China;Department of Electron and Information, Guilin institute of Electronic Technology, 541004, Guilin, China Institute of Medicine and Material Applied Technologies, Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University Department of Cardiology Yantai Yuhuangding Hospital Qingdao Medical College Qingdao University Yantai China; The Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education Chinese National Health Commission and Chinese Academy of Medical Sciences The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine Department of Cardiology Qilu Hospital of Shandong University Jinan China State Key Laboratory of Advanced Welding and Joining Shenzhen 518055 China; Flexible Printed Electronic Technology Center Shenzhen 518055 China; School of Materials Science and Engineering Shenzhen 518055 China School of Chemistry and Materials Science Heilongjiang University 150080 Harbin People's Republic of China; Key Laboratory of Chemical Engineering Process and Technology for High‐Efficiency Conversion, College of Heilongjiang Province 150080 Harbin People's Republic of China The Key Laboratory of Life-Organic Analysis, Qufu Normal University, Qufu 273165, Shandong, China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Qufu Normal University, Qufu 273165, Shandong, China Kunshan Centers for Disease Control and Prevention, Suzhou, Jiangsu, PR China; Departments of Experimental Hematology Beijing China The First Bethune Hospital, Jilin University, Changchun, Jilin 130021, China; College of Veterinary Medicine, Jilin University, Changchun, Jilin 130062, China The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine; School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu 273165; P. R. China School of Life Sciences, Huzhou University, Huzhou, Zhejiang 313000, P. R. China Stanley Ho Centre for Emerging Infectious Diseases The Chinese University of Hong Kong Hong Kong P.R. China Key Laboratory of Interface Science and Engineering in Advanced Materials, Ministry of Education, Taiyuan University of Technology, Taiyuan 030024, China Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China Division of Genetics, Department of Pediatrics, Loma Linda University, Loma Linda, CA, USA Laboratory of Liver Diseases; National Institutes of Health/NIAAA; Bethesda MD USA Department Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts 02118, Department of Chemistry, University of Natural Resources and Applied Life Sciences, Vienna, Austria, Department of Immunochemistry and Biochemical Microbiology, Leibniz Center for Medicine and Biosciences, D-23845 Borstel, Germany, and Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri 63110 Bascom Palmer Eye Institute Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL 33136, USA Collaborative Innovation Center of Chemical Science and Engineering, Key Laboratory for Green Chemical Technology, School of Chemical Engineering and Technology, Tianjin University 1 , Tianjin 300350, China Department of Spine Surgery; First Affiliated Hospital of Sun Yat-sen University; 58 Zhongshan Second Road Guangzhou P.R. China Department of Basic Science of Stomatology The Affiliated Stomatological Hospital of Nanjing Medical University Nanjing China; Jiangsu Province Key Laboratory of Oral Diseases Nanjing China; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing China Key Laboratory of Materials Chemistry for Energy Conversion and Storage (HUST) of Ministry of Education; School of Chemistry and Chemical Engineering; HUST; Wuhan 430074; China Health Care Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250011, P.R. China Engineering Research Center for Nanomaterials, Henan University, Kaifeng 475004, China; Collaborative Innovation Center of Nano Functional Materials and Applications of Henan Province, Kaifeng 475004, China Key Laboratory of Materials Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST), Wuhan 430074, China Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Wuhan 430061, China; Acupuncture and Moxibustion College, Hubei University of Chinese Medicine, Wuhan 430061, China Department of Orthopaedic Surgery Zhongnan Hospital of Wuhan University Wuhan China Department of Pathology Affiliated Cancer Hospital of Nantong University Nantong University Nantong School of Pharmaceutical Sciences,South‐Central University for Nationalities,Wuhan,China State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China Department of Hematological Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China Beijing Key Lab for Immune-Mediated Inflammatory Diseases, Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, China *Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892; Department of Endocrinology Tongji University School of Medicine Shanghai China 1Cancer Biology, Departments of Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control Institute of Crop and Nuclear Technology Utilization Zhejiang Academy of Agricultural Sciences Hangzhou 310021 China Stowers Institute for Medical Research and Division of Biology 156–29, California Institute of Technology, Pasadena, CA 91125 Department of Medical Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230032, China Key Lab of Material Chemistry for Energy Conversion and Storage of Ministry of Education School of Chemistry and Chemical Engineering Huazhong University of Science and Technology (HUST) Wuhan 430074 P. R. China Key Lab of Organic Optoelectronics and Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, China Global Medical Affairs, Biogen Idec Inc., San Diego, CA College of Acupuncture-Moxibustion and Orthopaedics, Hubei University of CM/Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Wuhan 430061, China. Department of Ophthalmology, The First Affiliated Hospital of Human Normal University/Hunan Provincial People's Hospital, Changsha 410002, Hunan, China. Department of Cardiology (H.W., K.C., M.D., Y.L., W.Z., J.Y.), Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, China. Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, P.R. China. Purification Development Genentech, Inc., One DNA Way South San Francisco CA 94080 State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, People's Republic of China; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, People's Republic of China Department of Chemistry, The Scripps Research Institute, La Jolla, California 94037, United States; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States Department of Toxicology School of Public Health, Anhui Medical University Hefei China Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guanghua Hospital of Stomatology, Sun Yat‑sen University, Guangzhou, Guangdong 510055, P.R. China Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei 230032, P. R. China College of Material Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, China Department of Materials Science and Engineering, Texas A&M University, College Station, Texas 77840, United States Department of Food Science and Nutrition, Fuli Institute of Food Science, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang R&D Center for Food Technology and Equipment, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China Laboratory Medicine Engineering Research Center for Nanomaterials Henan University Kaifeng 475004 China Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China; Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of the Ministry of Education, Sichuan University, Chengdu, Sichuan, China Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, PR China Computer Science and Engineering, University of Texas at Arlington, TX, USA. [email protected] Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , China Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China Department of Oncology The First Affiliated Hospital of Anhui Medical University Hefei China Department of Chemical and Biomolecular Engineering; University of Akron; Akron; USA Faculty of Metallurgy and Energy Engineering; Kunming University of Science and Technology; Kunming 650093; China; State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Department of Respiratory Disease, The Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou 310006, Zhejiang Province, China National Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China Department of Chemistry, School of Science and MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi’an Jiaotong University, Xi’an 710049, China Emergency Department, Qinghai Provincial People's Hospital, Xining, Qinghai 810007, P.R. China Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, China National & Local Joint Engineering Research Center for Applied Technology of Hybrid Nanomaterials, Henan University, Kaifeng 475004, P.R. China Department of Orthopedics Shandong Provincial Qianfoshan Hospital Jinan Shandong China National Laboratory of Plant Molecular Genetics Shanghai Institute of Plant Physiology and Ecology Shanghai Institute for Biological Sciences Graduate School of Chinese Academy of Sciences Shanghai 200032 China Peking University Fifth School of Clinical Medicine Beijing China 100730; Department of Cardiology, Beijing Hospital; National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medical Sciences Beijing China 100730 College of Acupuncture-moxibustion and Orthopedics-traumatology of Hubei University of Chinese Medicine, Hubei Provincial Collaborative Innovation Center for Preventive Treatment of Illnesses by Acupuncture and Moxibustion, Wuhan 430061, China. [email protected]. Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China Department of Pharmacology, Toxicology and Therapeutics,University of Kansas Medical Center,Kansas City,KS; Department of Toxicology, School of Public Health,Anhui Medical University,Hefei,China Department of Cardiology The Affiliated Yantai Yuhuangding Hospital of Qingdao University Yantai China State Key Laboratory of Advanced Welding and Joining; Harbin Institute of Technology (Shenzhen); Shenzhen 518055; China; Centre of Flexible and Printable Electronics Department of Microbiology, School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, People's Republic of China Department of Chemistry, Case Western Reserve University, Cleveland, OH a Key Laboratory of Integrated Regulation and Resource Development on Shallow Lake of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China; b College of Environment, Hohai University, Nanjing 210098, China Department of Cancer Radiotherapy, Jiangxi Cancer Hospital of Jiangxi Province, Nanchang, China Engineering Research Center for Nanomaterials, Henan University, Kaifeng, 475004, P. R. China Department of Gynecology Taizhou Hospital Affiliated to Nanjing University of Chinese Medicine Taizhou China Key Laboratory of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, China Department of Medicine, Central Arkansas Veterans Healthcare System and University of Arkansas for Medical Sciences, Little Rock, AR 72205-5446, USA. Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui Province, China. Department of Toxicology, School of Public Health Anhui Medical University Hefei China; Anhui Provincial Key Laboratory of Population Health & Aristogenics Anhui Medical University Hefei China; Laboratory of Environmental Toxicology Anhui Medical University Hefei China Department of Neurobiology and Department of Ophthalmology of the First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain‐Machine Integration, School of Brain Science and Brain Medicine Zhejiang University Hangzhou China National Health Commission Key Laboratory of Birth Defects Research , Prevention and Treatment, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan 410008 , China; Department of Medical Genetics , Hunan Children’s Hospital, Changsha, Hunan 410007 , China Department of Radiology, Tianjin Medical University Cancer Institute & Hospital, Tianjin, PR China Department of Scientific Research, Taizhou people's Hospital Affiliated to Nanjing University of Chinese Medicine , No. 366 Taihu Road, Taizhou 225300, China Neurocrine Biosciences, 12780 El Camino Real, San Diego, California 92130 Department of Forensic Science, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, Xinjiang, China College of Horticulture and Forestry, Huazhong Agricultural University, Wuhan 430070, China. Massachusetts Institute of Technology Earth Resources Lab, , Cambridge, Massachusetts, 02139, USA Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST), Wuhan 430074, China Key Laboratory of Medical Electrophysiology, Ministry of Education of China, Luzhou Medical College, Luzhou, China. Department of Hematology, Lymphoma Research Center, Peking University Third Hospital, Beijing, People’s Republic of China Jiangsu Key Laboratory of Oral Disease, Nanjing Medical University, Nanjing, China.; Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing, China. Shengjing Hospital of China Medical University, Shenyang, China Department of Hematologic Oncology Sun Yat‐sen University Cancer Center Guangzhou China; State Key Laboratory of Oncology in South China Guangzhou China; Collaborative Innovation Center for Cancer Medicine Guangzhou China Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030 Department of Traumatic Surgery, Center for Orthopaedic Surgery Third Affiliated Hospital of Southern Medical University Guangzhou China Hebei Medical University, No. 361, East Zhongshan Road, Shijiazhuang 050017, Hebei, China. Hubei University of Chinese Medicine, Wuhan, China Pediatric Research Institute Hunan Children's Hospital Changsha 410007 China Department of Anatomy, Li Ka Shing Faculty of Medicine, Neuropsychology Laboratory, the University of Hong Kong, Hong Kong Special Administrative Region, China. Department of Oncology,the First Affiliated Hospital of Anhui Medical University,Hefei,China; Inflammation and Immune Mediated Disease Laboratory of Anhui Province,Hefei,China Department of Chemistry and Physics; Louisiana State University; Shreveport; USA Department of Genetics, Harvard Medical School, Boston, MA 02115;; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215; Department of Surgery, Peking University School of Oncology, Beijing Cancer Hospital, Beijing, 100036, China. Departments of aMaterials Science and Engineering, School of Medicine, Jiangsu University, Zhenjiang 212013, Jiangsu, PR China Institute of Medicine and Materials Applied Technologies, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, Shandong 273165, P. R. China Computer Science and Engineering, University of Texas at Arlington, TX. Department of Ophthalmology, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu Province, China Shandong Province Key Laboratory of Life-Organic Analysis, School of Chemistry and Chemical Engineering, Qufu Normal University Guangzhou Institute of Respiratory Diseases, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120, China. Anhui Laboratory of Molecule-Based Materials, The Key Laboratory of Functional Molecular Solids, Ministry of Education, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241002, China State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi’an, China 1 Department of Computer Science and Engineering, University of Texas at Arlington, TX 76019 and 2Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China Department of Ultrasound, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 471000, P.R. China Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230036, People’s Republic of China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei 230032, People’s Republic of China School of Functional Food and Wine; Shenyang Pharmaceutical University; Shenyang 110016; China The Third Affiliated Hospital of Southern Medical University, Guangzhou, China Department of Ultrasound, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang City, Henan Province, China 1 Department of Computer Science and Engineering, University of Texas at Arlington, TX 76019, USA Acupuncture and Moxibustion Institute, College of Acupuncture & Moxibustion, Hubei University of Chinese Medicine and Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Wuhan 430061, China Department of Urology, General Hospital of Armed Police Forces of China, Beijing, China. Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 510060, P.R. China; State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, 510060, P.R. China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, P.R. China College of Environmental Science and Engineering, Hohai University, Nanjing 210098, China. [email protected] Authors' Affiliations: Departments of 1Pathology, 2Gastrointestinal Medical Oncology, and 3Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas; and 4Department of Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin Institute of Forestry and Pomology, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China. [email protected] Department of Neurobiology (H.W., S.G., J.T.), Medical College of Soochow University, Suzhou 215123, China; Department of Endocrinology (H.W., B.F.), East Hospital, Tongji University School of Medicine, Shanghai 200120, China The University of Texas MD Anderson Cancer Center Jiangsu Provincial Center for Disease Prevention and Control, Nanjing 210009, China. State Key Laboratory of Material Processing and Die & Mold Technology School of Materials Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China Faculty of Life Sciences, Northwestern Polytechnical University, Xi'an 710072, China. Department of Obstetrics and Gynecology, Xiangyang No.1 People’s Hospital, Affiliated Hospital of Hubei University of Medicine, Xiangyang, Hubei, China (mainland) College of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan 430061, China. [email protected]. College of Chemistry and Materials Science; Sichuan Normal University; Chengdu 610068; China Department of Neonatology, West China Second Hospital Sichuan University, Chengdu 610041, China. [email protected]. Department of Toxicology, Anhui Medical University, Hefei, China School of Earth Resources, China University of Geosciences (Wuhan), Wuhan 430074, China Department of Physiology, The Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA Kunming University of Science and Technology 2 Center of Metallurgical Energy Conservation and Emission Reduction, Ministry of Education, , Kunming 650093, China Department of Cardiothoracic Surgery, Nanchong Central Hospital, The Second Clinical College of North Sichuan Medical College, Nanchong, Sichuan 637900, China School of Chemistry Beijing Advanced Innovation Center for Biomedical Engineering Beihang University Beijing 100191 China School of Pharmacy, Jiangsu Provincial Key Laboratory of Coastal Wetland Bioresources and Environmental Protection Yancheng Teachers' University Yancheng Jiangsu People's Republic of China Department of Gastrointestinal Medical Oncology The University of Texas MD Anderson Cancer Center Houston TX USA ShenSi Lab Shenzhen Institute for Advanced Study University of Electronic Science and Technology of China Longhua District, Shenzhen 518110 P. R. China The Key Laboratory of Functional Molecular Solids, Ministry of Education, School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, China ZJU‐Hangzhou Global Scientific and Technological Innovation Center Hangzhou 310027 China Faculty of Life Sciences, Northwestern Polytechnical University, Xi'an, China. 2Department of Immunology, Genentech Inc., South San Francisco, CA 94080 Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China 3Cell Biology Program,; 4Center for Epigenetics Research, College of Bioscience and Biotechnology; Hunan Agricultural University; Changsha; P. R. China; Key Laboratory for Rural Ecosystem Health in Dongting Lake Area of Hunan Province Contribution from the Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588-0304, and IUMSC, Department of Chemistry, Indiana University, Bloomington, Indiana 47405 Institute of Quality Development, Kunming University of Science and Technology, Kunming 650093, China Institute of Aeronautical Meteorology and Chemical Defence; Beijing 100085; P. R. China Clinical College of Acupuncture-moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510405. School of Sociology and Population Studies, Nanjing University of Posts and Telecommunications, Nanjing 210023, China Anhui Medical University, Heifei 230032, China Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; *Department of Toxicology, Anhui Medical University, Hefei 230032, China;; †Laboratory of Environmental Toxicology, Hefei 230032, China; and Department of ICU, Wujin People Hospital, The Affiliated Hospital of Jiangsu University, Changzhou Shanghai Telebio Biomedical Co. Ltd. Hefei China College of Chemistry and Chemical Engineering, Yulin University, Yulin 719000, China; Shaanxi Provincial Key Laboratory of Clean Utilization of Low-Modified Coal, Yulin University, Yulin 719000, China State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China, and Xiangya Medical College, Central South University, Changsha 410078, P. R. China Department of Anesthesiology, Affiliated Hospital of Guilin Medical University 15 Lequn Rd, Guilin 541001, China. From the Eye Institute and affiliated Xiamen Eye Center of Xiamen University, Fujian, China; and the Department of Biology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, People's Republic of China National Center for Children’s Health (NCCH), Beijing, China; Department of Otorhinolaryngology Head and Neck Surgery, Beijing Children’s Hospital Affiliated to Capital Medical University, Beijing, China; Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery, Beijing, China Division of Microbiology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences 116023 Dalian P. R. China Institute of Electronics and Information, Guangdong Institute of Science and Technology, Guangzhou, Guangdong 510640, China Key Lab for Special Functional Materials of Ministry of Education; National and Local Joint Engineering Research Center for High-efficiency Display and Lighting Technology; School of Materials Science and Engineering; Collaborative Innovation Center of Nano Functional Materials and Applications, Henan University, Kaifeng, Henan 475004, P. R. China Shandong Province Key Laboratory of Life-Organic Analysis, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu City, Shandong 273165, P. R. China School of Medicine, Jiangsu University, Zhenjiang, China. NHC Key Laboratory of Birth Defect for Research and Prevention Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China Department of Dermatology, Children’s Hospital, Chongqing Medical University, Chongqing, China Department of Surgery, The Brooklyn Hospital Center, 121 Dekalb Avenue, Brooklyn, NY 11201, USA School of Chemistry and Environment, Beihang University, Beijing 100191, People’s Republic of China Department of Orthopedics, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China (mainland) The Key Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University, Beijing, 100083, China; Hefei Innovation Research Institute, Beihang University, Hefei, 100083, Anhui, China Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, China Key Laboratory of Functional Molecular Solids; Ministry of Education; School of Chemistry and Materials Science; Anhui Normal University; Wuhu College of Materials Science and Engineering, Wuhan Textile University, Wuhan, People’s Republic of China Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu Province, China Department of Urology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, P.R. China Department of Critical Care Medicine, Zhujiang Hospital Department of Neonatology, West China Second University Hospital of Sichuan University, Chengdu 610041, China. Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Jiangsu's Key Laboratory of Targeted Antiviral Research Nanjing Jiangsu Province China National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, Shanghai 200032, China 1Department of Epidemiology, University of California-Los Angeles School of Public Health; 2University of California-Los Angeles Jonsson Comprehensive Cancer Center; 3Departments of Pathology and Laboratory Medicine, University of California-Los Angeles David Geffen School of Medicine; 4Department of Human Genetics, University of California-Los Angeles, Los Angeles, California; 5Department of Social and Preventive Medicine, State University of New York, Buffalo, New York; 6Department of Epidemiology, School of Public Health, Fujian Medical University, Fuzhou, China; 7Taixing City Center for Disease Prevention and Control, Taixing City, Jiangsu, China; 8Fudan University School of Public Health, Shanghai, China; 9Gates Foundation Beijing Office, Beijing, China; and 10Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China Institute for Plant Protection and Soil Science, Hubei Academy of Agricultural Sciences, Wuhan 430064, China. The Key Laboratory of Functional Molecular Solids; Ministry of Education; School of Chemistry and Materials Science; Anhui Normal University; Wuhu NHC Key Laboratory of Birth Defects Research, Prevention and Treatment, Hunan Provincial Maternal and Child Health Care Hospital; Department of Maternal Health Care, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province Baylor College of Medicine, and Department of Gastrointestinal Medical Oncology (H.W.), The University of Texas Medical School at Houston, Houston, Texas 77030 Department of Policy Analysis and Management Cornell University Ithaca NY USA Institute of Pathogenic Microbiology, Jiangsu Provincial Center for Disease Prevention and Control, Key Laboratory of Enteric Pathogenic Microbiology, Ministry Health, Nanjing, China Department of Dermatology, Children's Hospital of Chongqing Medical University, Chongqing, China. Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People's Republic of China Department of Spine Surgery The First Affiliated Hospital of Sun Yat‐sen University Guangzhou People's Republic of China; Guangdong Province Key Laboratory of Orthopaedics and Traumatology Guangzhou People's Republic of China Department of Toxicology, Anhui Medical University, Hefei, Anhui, China The Second Affiliated Hospital of Nanchang University, Nanchang 330031, China Hubei Engineering Research Center for Biomaterials and Medical Protective Materials School of Chemistry and Chemical Engineering Huazhong University of Science and Technology Wuhan 430074 P. R. China At the time of this writing, Susan S. Kum (PhD candidate), Peng Wang, Zhu Jin, and Sara S. Metcalf were with the Department of Geography, University at Buffalo, Buffalo, NY. Hua Wang was with the Department of Communication, University at Buffalo. Leydis De La Cruz, Carol Kunzel, and Stephen E. Marshall were with the Section of Population Oral Health, Columbia University College of Dental Medicine, New York, NY. Mary E. Northridge was with the Department of Epidemiology & Health Promotion, New York... Key Laboratory for Green Chemical Technology of Ministry of Education; School of Chemical Engineering and Technology; Tianjin University; Tianjin 300072; China Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland Department of Epidemiology, University of Florida, Gainesville, Florida. Department of Orthopedic Surgery, Zhabei Central Hospital, Jing’an, Shanghai 200070, China Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China; Jiangsu Preventive Medicine Association, Nanjing, Jiangsu, China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Engineering, Kunming University of Science and Technology, Kunming 650093, Yunnan, China Department of Chemistry, Beijing Key Laboratory for Analytical Methods and Instrumentation Tsinghua University Beijing 100084 China; School of Chemistry and Environment Beihang University Beijing 100191 China Department of Computer Science, Colorado School of Mines, Golden, Colorado. Department of Pharmacy, The Third Hospital of Hebei Medical University, Shijiazhuang, China Biogen Idec, San Diego, CA National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, People's Republic of China. Medical College; Jiangsu University; Zhenjiang P.R. China NHC Key Laboratory of Birth Defects Research, Prevention and Treatment, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, PR China. Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, and State Key Laboratory of Materials Processing and Mold Technology; School of Chemistry and Chemical Engineering; Huazhong University of Science and Technology (HUST); Wuhan 430074; China Jiangsu Key Laboratory of Oral Diseases Nanjing Medical University Nanjing China Department of Pathology and Laboratory MedicineUniversity of Rochester Medical CenterRochesterNYUSA; Jiangsu Key Laboratory of Oral DiseasesNanjing Medical UniversityNanjingChina Department of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Peking University Third Hospital, Beijing, China State Key Laboratory of Medicinal Chemical Biology College of Life Sciences Nankai University Tianjin China; Department of Cell Biology and Genetics College of Life Sciences Nankai University Tianjin China Department of Chemistry and Physics Louisiana State University Shreveport LA 71115 USA Hainan Provincial Key Laboratory of Tropical Medicine; Hainan Medical College; Haikou China Department of Materials Science and Engineering Texas A&M University College Station TX 77843 USA The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine; School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu 273165, China Jiangsu Center of Disease Control, Jiangsu, China. Division of Research (B.S., C.P.Q., H.W., S.-F.J., S.S.), Kaiser Permanente, Oakland, California 94612 Department of Otorhinolaryngology, Head and Neck Surgery, Second Affiliated Hospital, Xi’an Jiaotong University School of Medicine, Xi’an, People’s Republic of China; NHC Key Laboratory of Birth Defect for Research and Prevention (Hunan Provincial Maternal and Child Health Care Hospital), 58 Xiangchun Road, Changsha, Hunan, China. Department of Computer Science and Engineering, University of Texas at Arlington, Arlington, TX. Institute of Forestry and Pomology Beijing Academy of Agriculture and Forestry Sciences Beijing China; Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) Ministry of Agriculture and Rural Affairs Beijing China; Beijing Engineering Research Center of Functional Floriculture Beijing China Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine (Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University), Hangzhou, P. R. China State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science & Technology, Tianjin, 300457, China Collaborative Innovation Center of Chemical Science and Engineering Key Laboratory for Green Chemical Technology of Ministry of Education School of Chemical Engineering and Technology Tianjin University Tianjin 300072 China Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China Institute of Radiation and Irradiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China. School of Materials Science and Engineering, Shandong University, Jinan 250061, China Department of Gynecological Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China; Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, China; Hubei Cancer Clinical Study Center, Wuhan, China Department of Urology The First Affiliated Hospital of Sun Yat‐Sen University Guangzhou China Department of Medical Genetics Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China; National Health Commission Key Laboratory of Birth Defects Research, Prevention and Treatment Changsha Hunan China Department of Spine Surgery Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology The First Affiliated Hospital of Sun Yat‐sen University Guangzhou China Hubei University of CM. School of Chemistry and Materials Science, Liaoning Shihua University, Fushun 113001, P. R. China Institute of Pathogenic Microbiology, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China Department of Chemistry The Scripps Research Institute La Jolla CA 92037 USA Department of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Department of Ultrasound, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China Department of Hepatobiliary Surgery, The Second Hospital of Lanzhou City Key Lab of Organic Optoelectronics and Molecular Engineering; Department of Chemistry; Tsinghua University; Beijing 100084; China Department of Oncology, The Affiliated Provincial Hospital of Anhui Medical University; Hefei, People's Republic of China State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. [email protected] Department of Computer Science and Engineering, University of Texas at Arlington, Arlington, TX, 76019, USA Department of Toxicology, School of Public Health Anhui Medical University Hefei 230032 China Comprehensive AIDS Research Center and Center for Global Health and Infectious Diseases, Beijing Advanced Innovation Center for Structural Biology, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, People’s Republic of China State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020, China. Department of Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, China Zhejiang Provincial Key Laboratory of Aging and Neurological Disorder Research, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China; Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, China. Department of Materials Science and Engineering, University of Illinois at Urbana–Champaign, Urbana, IL 61801; Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing 100191, China; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104-2499, USA. Shandong Province Key Laboratory of Life-Organic Analysis; College of Chemistry and Chemical Engineering; Qufu Normal University; Qufu City, P. R. China State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Division of Microbiology, 5100 Paint Branch Pkwy, HFS-711, College Park, MD 20740 Department of Pathology Tianjin Union Medical Center Tianjin China Department of Orthopedics The First Affiliated Hospital of Sun Yat‐Sen University Guangzhou China Engineering Research Center for Nanomaterials, Henan University, Kaifeng 475004, P. R. China Laboratory of Liver Diseases and the,National Institutes of Health,Bethesda,MD Department of Medical Genetics Maternal, Child Health Hospital of Hunan Province Changsha China; National Health Commission Key Laboratory of Birth Defects Research, Prevention and Treatment Hunan Provincial Maternal and Child Health Care Hospital Changsha China Department of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.; Department of Pathology, Peking University Third Hospital, Beijing 100191, China. Oncology, the First Affiliated Hospital of Anhui Medical University; Institute for Liver Diseases of Anhui Medical University, Hefei, Anhui Province, China Department of Swine Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, PR China Institute of Molecular Medicine, Clinical Laboratory, Department of Gastrointestinal Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China ICU Department, Wujin People's Hospital Affiliated with Jiangsu University and Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, P. R. China. Department of Spine Surgery The First Affiliated Hospital of Sun Yat‐sen University Guangzhou China; Sun Yan Sen University Pain Research Center Guangzhou China; Guangdong Province Key Laboratory of Orthopaedics and Traumatology Guangzhou China Department of Dermatology Children's Hospital of Chongqing Medical University Ministry of Education Key Laboratory of Child Development and Disorders Key Laboratory of Pediatrics in Chongqing Chongqing International Science and Technology Cooperation Center for Child Development and Disorders Chongqing China Department of Toxicology, School of Public Health, Anhui Medical University, Hefei 230032, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Hefei 230032, China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization/Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming, Yunnan, 650093, China The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China The University of Akron Department of Chemical and Biomolecular Engineering, , Akron, Ohio 44325-3906 School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu City 273165; China Department of Orthopedics Department of Dermatology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. Department of Ultrasound The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi China Department of Urology The First Affiliated Hospital Sun Yat‐sen University Guangzhou Guangdong China Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China *Department of Toxicology, Anhui Medical University, Hefei 230032, China;; ‡Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei 230032, China; The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong P. R. China State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, P. R. China; Chongqing Key Laboratory of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, P. R. China Key Lab of Inorganic Coating Materials, Shanghai Institute of Ceramics, CASS, Shanghai 200050, China, Key Lab for Special Functional Materials, Ministry of Education, Henan University, Kaifeng 475004, China, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka 563-8577, Japan, and ARC Centre of Excellence for Functional Nanomaterials, School of Chemical Engineering and AIBN, The University of Queensland, St Lucia, QLD 4072, Australia Molecular, Cellular, and Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, Kansas, USA Department of Urology, First Affiliated Hospital of Jiaxing Medical College, Jiaxing 314000, China Department of Neonatal, West China Second Hospital, Sichuan University, Chengdu 610041, China. The People's Hospital of Lianjiang City, Guangdong. [email protected] National Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China; School of Biomedical Sciences The Chinese University of Hong Kong Shatin New Territories Hong Kong Department of Chemistry; School of Science and MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter; Xi'an Jiaotong University; Xi'an 710049; China Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA; Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing, China Department of No.2 Surgery, First People's Hospital of Yidu City, Yidu Hubei 443300, PR China. Authors' Affiliations: 1Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center; 2Program in Genes & Development, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas; 3Department of Surgical Oncology, the First Affiliated Hospital, China Medical University, Shenyang, Liaoning, PR China; 4Department of Oncology, Chi-Mei Medical Center, Tainan, Taiwan; Departments of 5GI Medical Oncology, 6Pathology, 7General Internal Medicine, Ambulatory Treatment, and Emergency Care, 8Endocrine Neoplasia and Hormonal Disorders, and 9Program in Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas Department of Chemical Engineering, National ESCA and Surface Analysis Center for Biomedical Problems, and University of Washington Engineered Biomaterials (UWEB), University of Washington, Seattle, Washington 98195 Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China Division of Endocrinology, Department of Internal Medicine, Central Arkansas Veterans Healthcare System and College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Key Lab for Special Functional Materials of Ministry of Education, Henan University, Kaifeng 475004, China Jiangsu Provincial Center for Disease Prevention and Control Nanjing China Department of Nuclear Science and Engineering and Department of Materials Science and Engineering Massachusetts Institute of Technology Cambridge MA 02139 USA Department of Experimental Hematology, Beijing Institute of Radiation Medicine of China, Academy of Military Medical Sciences, Beijing, China College of Enology, Northwest A&F University , Yangling , China; Shaanxi Engineering Research Center for Viti-Viniculture , Yangling , China Department of Pediatric Internal Medicine, The First People’s Hospital of Kunshan Affiliated to Jiangsu University, Kunshan 215300, China 1Gastrointestinal Medical Oncology, Departments of Department of Oncology the First Affiliated Hospital of Anhui Medical University Hefei China Department of Chemistry, University of Oxford, Oxford, United Kingdom Department of Hematological Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, China; State Key Laboratory of Oncology in South China, Guangzhou, 510060, China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana and Champaign, IL 61801 State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro‐products Institute of Virology and Biotechnology Zhejiang Academy of Agricultural Sciences Hangzhou China Department of Materials Science and Engineering, College of Engineering and College of Science, Texas A&M University, College Station, Texas 77843, United States Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, People's Republic of China; AnKang Hospital of Traditional Chinese Medicine, Ankang 725000, Shaanxi Province, China. Kunshan Centers for Disease Control and Prevention, Jiangsu, China; Jiangsu Provincial Public Health Research Institute Kunshan Branch, Jiangsu, China School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China School of Life Sciences, Xiamen University, South Xiang’an Road, Xiamen 361102, China Hunan Key Laboratory of Super Microstructure and Ultrafast Process; School of Physics and Electronics; Central South University; Changsha; China Department of Urology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China. Institute of Laboratory Medicine, School of medicine, Jiangsu University, Zhenjiang, China School of Materials Science and Engineering Nanyang Technological University Nanyang Avenue Singapore 639798 Singapore Jiangsu Province Environment Monitoring Centre, Nanjing 210036, China Department of Surgery, The Brooklyn Hospital Center, 121 Dekalb Avenue, Brooklyn, NY 11201, USA; Department of Surgery, Westchester Medical Center, New York Medical College, 100 Woods Road, Valhalla, NY 10595, USA Department of Orthopedics, Zhabei Central Hospital, Jing’an District, Shanghai 200070, China School of Biological Science and Medical Engineering, Beihang University, 100083 Beijing, China; Hefei Innovation Research Institute, Beihang University, 230013 Hefei, China Systems Biology and Medicine Center for Complex Diseases, Affiliated Hospital of Qingdao University, Qingdao, China; Department of Research Management, Affiliated Hospital of Qingdao University, Qingdao, China. Electronic address: [email protected]. Department of Bone and Joint, The Second Clinical Medical College (Shenzhen People’s Hospital), Jinan University, Shenzhen 518020, China School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue 639798 Singapore Department of Medical Genetics Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China; NHC Key Laboratory of Birth Defects Research Prevention and Treatment (Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China Shandong Province Key Laboratory of Life-Organic Analysis; College of Chemistry and Chemical Engineering; Qufu Normal University; Qufu City; P. R. China Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Wuhan, China Department of General Surgery, Nantong University Affiliated Hospital, Nantong, Jiangsu 226001, China Division of Endocrinology and Metabolism and Endocrinology Section, John L. McClellan Jr. Memorial Veterans Hospital and University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 School of Chemistry Beihang University Beijing 100191 P. R. China Department of Tuberculosis, Anhui Chest Hospital, Hefei, Anhui, China Department of General Surgery, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010050, China School of Chemistry and Environment Beihang University Beijing 100191 China Division of Endocrinology and Metabolism, Department of Medicine, University of Arkansas for Medical Sciences College of Medicine, Little Rock, Arkansas; Endocrine Division, Medicine and Research Services, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas Chengyue Li, Mei Sun, Ying Wang, Li Luo, and Mo Hao are with the Research Institute of Health Development Strategies and Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai, China. Mingzhu Yu and Jingjin Yu are with the Department of the Bureau of Disease Control and Prevention of National Health and Family Planning Commission, Beijing, China. Yu Zhang is with the Department of Health and Family Planning Commission of Hubei Province, Wuhan, Hubei, China. Hua... Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, HUST, Wuhan 430074, China Department of Spine Surgery; The First Affiliated Hospital; Sun Yat-sen University; Guangzhou 510080, Guangdong China Key Laboratory of Organic Optoelectronics & Molecular Engineering Department of Chemistry Tsinghua University Beijing 100084 China Key Laboratory of Biology and Cultivation of Herb Medicine, Ministry of Agriculture and Rural Affairs, Institute of Chinese Herbal Medicines, Hubei Academy of Agricultural Sciences, Enshi 445000, China Children’s Hospital of Chongqing Medical University Chongqing China Department of Toxicology, School of Public Health Anhui Medical University Hefei Anhui PR China Department of Antibody Engineering, Genentech, South San Francisco, California Department of Urology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, China. [email protected] Tianjin Institute for Women’s Health, Tianjin, China Jiangsu Provincial Centre for Disease Control and Prevention, Nanjing 210009, China Respiratory Medicine, Shaoxing People’s Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, Zhejiang, China Institute for Plant Protection and Soil Science; Hubei Academy of Agricultural Sciences; Wuhan; China The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, P.R. China; Jiangsu Province Key Laboratory of Oral Diseases, Nanjing, P.R. China; Jiangsu Province Engineering Research Center of Stomatological Translation Medicine, Nanjing, P.R. China Department of Gastroenterology, The Second People's Hospital of Hefei Hefei 230000, Anhui, China. Laboratory of Liver Diseases, Laboratory of Cardiovascular Physiology and Tissue Injury, National Institute on Alcohol Abuse and Alcoholism,National Institutes of Health,Bethesda,MD Center for Cell and Gene Therapy1 and School of Software, Shandong University , Jinan, China Department of Urology, Cancer Hospital of Zhejiang Province, Hangzhou 310022, China. Key Laboratory of Industrial Ecology and Environment Engineering (Ministry of Education, China), Faculty of Chemical, Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, China; School of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China Institute of Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Prevention and Control, 172 Jiangsu Road, Nanjing 210009, China Key Laboratory of Interface Science and Engineering in Advanced Materials; Taiyuan University of Technology; Taiyuan; China Department of Medical Genetics Hunan Provincial Maternal and Child Health Care Hospital Changsha PR China; National Health Commission Key Laboratory of Birth Defects Research Prevention and Treatment Changsha PR China Ministry of Education Key Laboratory of Interface Science and Engineering in Advanced Materials; Research Center of Advanced Materials Science and Technology; Taiyuan University of Technology; Taiyuan 030024; China Department of Cardiology Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, People’s Republic of China Key Lab for Special Functional Materials of Ministry of Education, National & Local Joint Engineering Research Center for High-efficiency Display and Lighting Technology, School of Materials Science and Engineering, and Collaborative Innovation Center of Nano Functional Materials and Applications, Henan University, Kaifeng, 475004, People’s Republic of China School of Mechatronics Engineering and Automation of Shanghai University, Shanghai Key Laboratory of Power Station Automation Technology, Shanghai - PR China Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China. The Key Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science; Anhui Normal University; Wuhu; China CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China Key Laboratory of Interface Science and Engineering in Advanced Materials; Ministry of Education; Taiyuan University of Technology; Taiyuan 030024; P. R. China School of Electrical and Computer Engineering; Georgia Institute of Technology; Atlanta; USA Pediatric Research Institute, Hunan Children’s Hospital, Changsha, Hunan 410007, China Zhejiang Cancer Hospital, Hangzhou, China 1 Beijing Institute of Radiation Medicine, Beijing, People's Republic of China Department of Urology, Zhejiang Cancer Hospital, Hangzhou 310022, China (Email: [email protected]). Acupuncture and Traumatology College, Hubei University of Traditional Chinese Medicine, Wuhan. Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, P.R. China. Department of Communication, University at Buffalo, The State University of New York, 359 Baldy Halll, Buffalo, NY 14260, USA. Key Lab of Photovoltaic and Energy Conservation Materials; Institute of Solid State Physics; HFIPS; Chinese Academy of Sciences; Hefei 230031 Hubei Academy of Agricultural Sciences, 117996, Wuhan, Hubei , China; Department of Pathology and Laboratory MedicineUniversity of British Columbia Vancouver Canada; School of Medical Science and Laboratory MedicineJiangsu University Jiangsu People's Republic of China Department of Pathology - 085 University of Texas M.D. Anderson Cancer Center 515 Holcombe Blvd. Houston, TX 77030 State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, PR China School of Computer Science and Engineering, Northeastern University, Shenyang, Liaoning, China State Key Laboratory of Material Processing and Die and Mold Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China Center for Research and Development of Fine Chemicals, Key Laboratory of Green Pesticide and Agriculture Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, People's Republic of China Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 354 Fenglin Road, Shanghai 200032, China [email protected] Shijiazhuang Junlebao Dairy Co. Ltd., Shijiazhuang, Hebei, China State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China Department of General Surgery Public Health Clinical Center of Chengdu Jingju Temple 18# 610066 Chengdu China Guangdong Jiana Energy Technology Co Ltd, Qingyuan 511500, China Department of Spine Surgery The First Affiliated Hospital of Sun Yat‐sen University No.58 Zhongshan 2nd Road Guangzhou 510080 China State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China, and Hematology Department, Xiangya Hospital, Central South University, Changsha 410008, P. R. China Department of Cardiology West China Hospital of Sichuan University Chengdu China Neonatal Intensive Care Unit, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China. College of Enology, Northwest A & F University, Yangling, China; Shaanxi Engineering Research Center for Viti-Viniculture, Yangling, China; Heyang Experimental and Demonstrational Stations for Grape, Weinan, China Hubei Provincial Collaborative Innovation Center of Preventive Treatment; Wuhan 430065; PR China; Department of Acupuncture and Moxibustion; Hubei University of Chinese Medicine 1Thoracic Surgery I, and Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Departments of Key Laboratory of Enteric Pathogenic Microbiology, Ministry of Health, Microbiological Laboratory, Jiangsu Center for Disease Prevention and Control (CDC), 172 Jiangsu Rd, Nanjing 210009, China College of Acu-moxibustion and Orthopedics, Hubei University of Chinese Medicine, Wuhan 430061, China. [email protected] Institute of Organic Chemistry, Faculty of Chemistry and Pharmacy, University of Regensburg, 93040 Regensburg, Germany Shandong Province Key Laboratory of Life-Organic Analysis, Qufu Normal University, Qufu, People's Republic of China Shandong Province Key Laboratory of Life-Organic Analysis; School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu City 273165, P.R. China Department of Forensic Science, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, P. R. China National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant Sciences Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences 300 Fenglin Road Shanghai 200032 China Key Laboratory of Integrated Regulation and Resource Development on Shallow Lake of Ministry of Education; College of Environment, Hohai University; NO.1 Xikang Road, Gulou District Nanjing Jiangsu Province China 210098 School of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Purification Development Genentech, Inc., One DNA Way South San Francisco California Taiyuan University of Technology; Key Laboratory of Interface Science and Engineering in Advanced Materials of Taiyuan University of Technology Jiangsu Center for Disease Control and Prevention, Nanjing, China (H.W.). Department of ICU, Wujin People Hospital Affiliated with Jiangsu University, and the Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, P. R. China. Department of Metabolic and Cardiovascular Diseases, Novartis Institutes for Biomedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, Hoffmann-La Roche, 340 Kingsland Street, Nutley, New Jersey 07110, and Array BioPharma, 3200 Walnut Street, Boulder, Colorado 80301 Key Laboratory of Textile Fiber & Product (Ministry of Education), College of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, Hubei, China; High-Tech Organic Fibers Key Laboratory of Sichuan Province, Sichuan Textile Science Research Institute, Chengdu 610072, Sichuan, China Jiangsu Center for Disease Control and Prevention Nanjing China College of Acupuncture and Orthopedics, Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion Authors' Affiliation: The University of Texas M. D. Anderson Cancer Center, Houston, Texas Eye Institute and Affiliated Xiamen Eye Center, Xiamen University, Xiamen, Fujian, China School of Metallurgy and Energy Engineering, Kunming University of Science and Technology, China State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control Institute of Quality and Standard for Agro‐Products Zhejiang Academy of Agricultural Sciences Hangzhou 310021 China Department of Biology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China; Department of Cell Biology and Genetics, The Key Laboratory of Bioactive Materials Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China Department of Pediatric Neurology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China Duanshen township hospital Wuyuan of Jiangxi China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization, Kunming University of Science and Technology, Kunming 650093, Yunnan, China Beijing Institute of Radiation Medicine, Beijing 100850, P.R. China U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Division of Microbiology, College Park, Maryland, USA Department of Endocrinology, Baoshan Branch, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China Department of Laboratory Medicine of Renji Hospital of School of Medicine, Shanghai Jiaotong University, Shanghai 200240, China School of Chemistry and Environment Beihang University Beijing 100191 P.R. China Orthopedics, Hubei University of Chinese Medicine, Wuhan 430061, China. [email protected] Department of Oncology, Second Affiliated Hospital of Nanchang University; Nanchang University, Nanchang 330006, Jiangxi Province, China. Department of Mechanical and Energy Engineering, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, People's Republic of China. Anhui Chest Hospital, Hefei City, Anhui Province, China. Department of Neonatology, West China Second Hospital, Sichuan University, Chengdu 610041, China. [email protected]. Department of Chemical Engineering, University of Washington, Seattle, Washington 98195 4Jiangsu Center for Disease Control and Prevention, Nanjing, China Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 3 Department of Mathematical Sciences, Georgia Southern University, Statesboro, GA, USA Yidu Central Hospital of Weifang College of Enology, Northwest A&F University, Yangling 712100, China; China Wine Industry Technology Institute, Yinchuan 750021, China; Shaanxi Engineering Research Center for Viti-Viniculture, Yangling 712100, China Department of Instrumentation and Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. [email protected] Collaborative Innovation Center of Social Risks Governance in Health, Fudan University, Shanghai 200032, China; Jiangsu Preventive Medicine Association, Nanjing, Jiangsu 210009, China the First Affiliated Hospital of Hunan University of Chinese Medicine Changsha 410007,China. Guangdong Jiana Energy Technology Co Ltd. Qingyuan 511500 P. R. China; Qingyuan Jiazhi New Material Research Institute Co. Ltd. Qingyuan 511500 P. R. China Key Laboratory of Special Functional Aggregated Materials & Key Laboratory of Colloid and Interface Chemistry; (Shandong University); Ministry of Education; School of Chemistry and Chemical Engineering; Shandong University Centre for Applied Informatics, College of Engineering and Science, Victoria University, P.O. Box 14428, Melbourne, VIC 8001, Australia School of Biomedical Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong China Gastrointestinal Medical Oncology State Key Laboratory for Mechanical Behavior of Materials and Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China Department of Dermatology Children's Hospital of Chongqing Medical University Ministry of Education Key Laboratory of Child Development and Disorders China International Science and Technology Cooperation base of China Development and Critical Disorders Chongqing Key Laboratory of Pediatrics Chongqing China Key Laboratory for Green Chemical Technology of Ministry of Education; School of Chemical Engineering and Technology; Tianjin University; Collaborative Innovation Center of Chemical Science and Engineering; Tianjin 300072 Department of Chemistry, Washington State University, Pullman, Washington 99164 State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization; Faculty of Metallurgical and Energy Engineering; Kunming University of Science and Technology; Kunming 650093; China The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China Key Laboratory of Material Chemistry for Energy Conversion and Storage (HUST), Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology (HUST), Wuhan 430074, China Hunan Provincial Maternal and Child Health Care Hospital Changsha China Medical Systems Biology Center for Complex Diseases Affiliated Hospital of Qingdao University Qingdao China Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Laboratory of Molecule-Based Materials (State Key Laboratory Cultivation Base), College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China Department of General Surgery, Affiliated Hospital of Nantong University, Nantong University, Nantong, PR China 2Gastrointestinal Medical Oncology, and Key Lab for Special Functional Materials of Ministry of Education, Henan University, Kaifeng, 475004, China The Department of Lymphoma/Myeloma The University of Texas MD Anderson Cancer Center Houston TX USA 4The Lundquist Institute, Torrance, CA; 5David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 2Cancer Biology and Department of Cardiology, West China Hospital, Sichuan University College of Horticulture and Forestry Science, Hubei Engineering Technology Research Center for Forestry Information, Huazhong Agricultural University, Wuhan 430070, China Center of Ophthalmology and Optometric, People’s Hospital of Hunan Province, Changsha, China National Health Commission Key Laboratory of Birth Defects Research, Prevention and Treatment, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan 410008, China; Department of Medical Genetics, Maternal and Child Health Hospital of Hunan Province, Changsha, Hunan 410008, China Department of Cancer Biology (S.G., H.W., Y.-F.W., Z.W.), The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030; National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, 230032, P. R. China Center of Analysis and Measurement, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China Shandong Province Key Laboratory of Life-Organic Analysis, School of Chemistry and Chemical Engineering, Qufu Normal Univesity Clinical Medicine, Medical College, Nantong University , Jiangsu , 226001 , China; Department of Breast and Thyroid Surgery, Affiliated Hospital of Nantong University , Jiangsu , 226001 , China Policy Research Center for Environment and Economy (PRCEE), China Ministry of Environmental Protection, Beijing, China School of Chemistry and Environment Key Laboratory of Bio‐Inspired Smart Interfacial Science and Technology of Ministry of Education Beihang University Beijing 100191 P. R. China Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu 273165, People’s Republic of China Department of Orthopaedics, Associated Hospital, Beihua University Jilin, China. Department of Toxicology; Anhui Medical University; Hefei China; Anhui Provincial Key Laboratory of Population Health & Aristogenics; Hefei China Department of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China Department Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA Key Laboratory of Tropical Diseases and Translational Medicine of the Ministry of Education & Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical College Haikou China; Department of Cell Biology School of Basic Medical Science, Southern Medical University Guangzhou China Department of Materials Science and Engineering; University of Illinois at Urbana–Champaign; Urbana; USA School of Chemistry and Environment; Beihang University; Beijing 100191; P. R. China Agricultural Committee of Dongtai, Dongtai 224200, Jiangsu, China. The Departments of Lymphoma/Myeloma The University of Texas MD Anderson Cancer Center Houston Texas USA Key Laboratory of Material Chemistry for Energy Conversion and Storage (HUST) of Ministry of Education School of Chemistry and Chemical Engineering Huazhong University of Science and Technology (HUST) Wuhan 430074 China Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, USA; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, China Department of Dermatology Children's Hospital of Chongqing Medical University Chongqing China Institute of StomatologyJiangsu Key Laboratory of Oral DiseasesNanjing Medical UniversityNanjingChina; Department of Pathology and Laboratory MedicineUniversity of Rochester Medical CenterRochesterNYUSA Neonatal Intensive Care Unit, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China. [email protected] Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children's Health, Beijing, China; Department of Acute Infectious Disease Control and School Health, Kunshan Centers for Disease Control and Prevention, Suzhou, Jiangsu, PR China; Research & Development Center Mageline Biology Tech Co., Ltd. Wuhan Hubei China College of Enology, Northwest A&F University, Yangling, Shaanxi, PR China; Shaanxi Engineering Research Center for Viti-Viniculture, Yangling, Shaanxi, PR China; China Wine Industry Technology Institute, Zhongguancun innovation Center, Yinchuan, Ningxia, PR China Department of Hematological Oncology, Cancer Center, Sun Yat-Sen University, Guangzhou, China Department of Pediatrics, West China Second University Hospital, Sichuan University, Sichuan, Chengdu 610041, PR China. College of Chemistry and Materials Science; Sichuan Normal University; Chengdu; People's Republic of China Department of Neurobiology, Medical College of Soochow University, Suzhou 215123, P.R. China. Department of Molecular Oral Medicine and Maxillofacial Surgery 1, Hiroshima University Faculty of Dentistry, 1-2-3 Kasumi, Minami-Ku, Hiroshima 734-8553, Japan; National Stem Cell Resource, American Type Culture Collection, Manassas, VA 20110-2209; Central Research Laboratories, ZERIA Pharmaceutical Co., Ageo 360-0111, Japan; and Center for Cancer Biology and Nutrition, Institute of Bioscience and Technology, Texas A & M University System Health Science Center, Houston, TX 77030-3303 Systems Biology & Medicine Center for Complex Diseases Affiliated Hospital of Qingdao University Qingdao China Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China; Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of the Ministry of Education, Sichuan University, Chengdu, China Department of Urology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China (mainland) Department of Laboratory Medicine, Taizhou People's Hospital, Taizhou City, China. Immunology Contribution from the Department of Organic Chemistry, Safra Campus, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 91904, Israel, Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588-0304, and School of Chemistry, The Sackler Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel Dermatological Department (Department of Cosmetic Dermatology, Department of Surgery of Traditional Chinese Medicine), Baoji Hospital of Traditional Chinese Medicine, Baoji, Shaanxi, China Department of Pediatrics Shengjing Hospital of China Medical University Shenyang China Department of Materials Science and Engineering; University of Illinois at Urbana-Champaign; Urbana; USA Key Laboratory for Special Functional Materials of Ministry of Education, Henan University, Kaifeng, 475004, China, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China, and Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China Basic Medical College of Xinjiang Medical University, Urumqi, Xinjiang, China (mainland) Department of Oncology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China From the Departments of *Pathology, †Gastrointestinal Medical Oncology, ‡Surgical Oncology, and §Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX. The Key Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, China 23Department of Obstetrics and Gynecology, Xiangyang First People's Hospital affiliated to Hubei University of Medicine, Xiangyang, Hubei, China. Department of Infectious Disease Control, Kunshan Centers for Disease Control and Prevention, Kunshan, Jiangsu Province, China Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China. Ankang Hospital of Traditional Chinese Medicine, Ankang 725000, Shaanxi Province, China. Institute of Pathogen Microbiology, Jiangsu Provincial Center for Disease Prevention and Control, Key Laboratories of Enteric Pathogenic Microbiology, Ministry of Health, Nanjing, China 1Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Laboratory Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Institute of Stomatology, Nanjing Medical University, Jiangsu Key Laboratory of Oral Diseases Nanjing China; Department of Pathology and Laboratory Medicine University of Rochester Medical Center Rochester NY USA State Key Laboratory of Catalysis iChEM Gold Catalysis Research Center Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China School of Computer Science and Engineering, Northeastern University, Shenyang 110819, Liaoning, China; State Key Laboratory of Software Architecture, Neusoft Corporation, Shenyang 110179, Liaoning, China; Research Center of Safety Engineering Technology in Industrial Control, Neusoft Group Research, Shenyang 110179, Liaoning, China; Engineering Research Center of the Ministry of Education in Security Protection for Complex Networks and Systems, Northeastern University, Shenyang 110819, Liaoning, China University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Department of Hematology, Hainan General Hospital, Haikou, Hainan 570311, P.R. China State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P.R. China School of Mechanical and Power Engineering Nanjing Tech University Nanjing China Department of Pathology, Peking University Health Science Center, Beijing 100083, China. Beijing Academy of Forestry and Pomology Sciences Beijing Academy of Agriculture and Forestry Sciences Beijing China; Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China) Ministry of Agriculture and Rural Affairs Beijing China Department of Orthopaedic Surgery Zhongnan Hospital Wuhan University Wuhan China Molecular, Cellular, and Developmental Biology Program, Arthropod Genomics Center, Division of Biology, Kansas State University, Manhattan, KS 66506, USA Email: [email protected]. From the Departments of Anatomical Pathology (Drs Nagaria and Huamin Wang), Gastrointestinal Medical Oncology (Dr Hua Wang), and Translational Molecular Pathology (Dr Huamin Wang), The University of Texas MD Anderson Cancer Center, Houston; and the Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri (Dr Chatterjee). Department of Cardiology, Beijing Hospital, National Center of Gerontology Institute of Geriatric Medicine, Chinese Academy of Medical Sciences Beijing China Department of Cardiology, Beijing Hospital, National Centre of Gerontology, Beijing, China; Department of Chemical and Biomolecular Engineering; The University of Akron; Akron; USA National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China Second Affiliated Hospital of Nanchang University Nanchang China Medical Department, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Dong Dan, Beijing, People’s Republic of China Department of Radiology, Ningbo Number 6 Hospital, Ningbo, Zhejiang 315040, P.R. China 3Stanford Cancer Institute, Stanford, California.; 5Program in Epithelial Biology, Stanford Cancer Institute, Stanford, California. Key Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241002, China Division of Endocrinology (H.W., S.K.D., R.L.C., W.S.C., N.S., S.C.E.), Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205; Research and Medicine Services (H.W., S.K.D., S.C.E.), Central Arkansas Veterans Healthcare System, North Little Rock, Arkansas 72114 State Key Laboratory of Material Processing and Die & Mold Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China Department of Spine Surgery, the First Affiliated Hospital and Orthopedic Research Institute of Sun Yat-sen University, Guangzhou, China Department of Laboratory Medicine, Renji Hospital, School of MedicineShanghai Jiaotong University 200127 Shanghai China School of Chemistry and Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, People's Republic of China Ophthalmology Department, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, China Department of Pediatric Neurology Shengjing Hospital of China Medical University Shenyang China Institute of Preventive Genomic Medicine, School of Life Sciences Northwest University Xi'an China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences Northwest University Xi'an China Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China College of Enology, Northwest A&F University, Xianyang 712100, China; China Wine Industry Technology Institute, Yinchuan 750021, China; Shaanxi Engineering Research Center for Viti-Viniculture, Xianyang 712100, China Department of Cardiology Yuhuangding Hospital, The Fourth School of Clinical Medicine of Qingdao University, Yantai Yantai China State Key Laboratory of New Textile Materials & Advanced Processing Technology, Hubei Key Laboratory for New Textile Materials and Applications, School of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, P. R. China The First Affiliated Hospital of Anhui Medical University, Hefei 230022, P.R. China National & Local Joint Engineering Research Center for Applied Technology of Hybrid Nanomaterials; Henan University Jinming Street Kaifeng; 475004 P.R. China Orthopaedics, People's Hospital of Putuo District, Shanghai, China. Department of Oncology the First Affiliated Hospital of Anhui Medical University Hefei Anhui China Laboratory of Liver Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Bethesda MD USA; Institute for Liver Diseases; Anhui Medical University; Hefei China Jiangsu Provincial Center for Disease Control and Prevention. State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, 510060 Guangzhou, Guangdong, P.R. China; Department of Hematological Oncology, Sun Yat-Sen University Cancer Center, 510060 Guangzhou, Guangdong, P.R. China; Collaborative Innovation Center of Cancer Medicine, Sun Yat-Sen University Cancer Center, 510060 Guangzhou, Guangdong, P.R. China Department of Orthopaedics, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Second Road, Guangzhou, P.R. China Department of Cardiology, Heart Failure Center, Capital Medical University, Beijing Chao-Yang Hospital, Beijing, China;; Beijing Key Laboratory of Metabolic Disorders Related Cardiovascular Diseases, Beijing, China Department of Laboratory Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States Medical College Jiangsu University Zhenjiang China Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Anhui Provincial Laboratory of Inflammatory and Immune Diseases, Hefei, Anhui, China Institute of Medicine and Materials Applied Technologies; College of Chemistry and Chemical Engineering; Qufu Normal University; Qufu; P. R. China Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China. Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA Department of Neurosurgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China; Zhejiang Provincial Key Laboratory of Aging and Neurological Disorder Research, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China Department of Obstetrics, Affiliated Hospital of Jiangsu University, Zhenjiang, China Departments of Radiation Oncology and Hunan Province Maternal and Children Care Hospital, Changsha, China 0 Key Laboratory of Tectonics and Petroleum Resources of Ministry of Education, China University of Geosciences, Wuhan 430074, China; School of Earth Resources, China University of Geosciences, Wuhan 430074, China Center for Food Safety and Applied Nutrition, US Food and Drug Administration, 5100 Paint Branch Parkway, College Park, MD 20740, USA Department of Endocrinology, Baoshan Branch Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai China The Third People’s Hospital of Xindu District, Chengdu, Sichuan Province, China Department of Hematological Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, China Jiangsu Key Laboratory of Oral Diseases Nanjing Medical University Nanjing China; Department of Orthodontics, Affiliated Hospital of Stomatology Nanjing Medical University Nanjing China Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, PRC Department of Hematological Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Guangzhou, China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, China Department of Oral and Maxillofacial Surgery, Clinical Laboratory, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat‑sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, Guangdong 510055, P.R. China Institute for Child Health Policy, Florida University Department of Obstetrics and Gynecology, Taizhou Hospital of Traditional Chinese Medicine,Taizhou, Jiangsu 225300, P.R. China Key Lab for Special Functional Materials of Ministry of Education, Henan University, Kaifeng, 475004, China, and College of Chemistry and Chemical Engineering, Henan University, Kaifeng, 475004, China Department of Acu-moxibustion and Osteo-traumatology, Hubei College of Chinese Medicine, Wuhan 430061, China. Department of Infectious Disease Control, Kunshan Centers for Disease Control and Prevention, 215300 Kunshan, Jiangsu Province, China Department of Intensive Care, Zhujiang Hospital Southern Medical University Guangzhou China Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China. [email protected]. Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850, People's Republic of China. Department of Spine Surgery The 1st Affiliated Hospital of Sun Yat‐sen University Guangzhou Guangdong PR China School of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, 150040 Harbin, China Anhui Key Laboratory of Water Pollution Control and Waste Water Recycling, Anhui Jianzhu University, Hefei 230601, China; Anhui Key Laboratory of Environmental Pollution Control and Waste Resource Utilization, Anhui Jianzhu University, Hefei 230601, China Heart Center and Beijing Key Laboratory of Hypertension Research, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China Department of Chemical Engineering, School of Water and Environment, Chang’an University, Xi’an710064, China Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, People’s Republic of China National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China (B.X., H.W., H.H.); State Key Laboratory of Genetic Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200433, China (Z.L., Y.Z., A.D.); and Department of Biol Department of Cardiology HuaXi Hospital of Sichuan University Chengdu Sichuan China College of Acupuncture-Moxibustion and Orthopedics and Traumatology, Hubei University of CM, Wuhan 430061, China. Department of Ecology School of Life Science Nanjing University Nanjing China Collaborative Innovation Center of Chemical Science and Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China Red Cell Physiology Laboratory, New York Blood Center, New York, NY; Department of Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA Department of Electrical Engineering; California Institute of Technology; Pasadena, USA; Department of Electrical and Computer Engineering; Georgia Institute of Technology Division of Pediatric Neurology, Department of Pediatrics, Shengjing Hospital, China Medical University, Shenyang 110004, China. [email protected]. Key Laboratory of Materials Physics, CAS Center for Excellence in Nanoscience, and Anhui Key Laboratory of Nanomaterials and Nanotechnology, Institute of Solid State Physics, Chinese Academy of Sciences, Hefei 230031, China Department of Oncology, the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei 230036, P. R. China State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization; Kunming University of Science and Technology; Kunming 650093; China; Faculty of Metallurgical and Energy Engineering From the Institute for Clinical Evaluative Sciences (M.K.K., H.W., M.M., J.V.T.), Division of General Internal Medicine and Clinical Epidemiology, and Women’s Health Program, University Health Network (M.K.K), Clinical Epidemiology and Health Care Research Program and Division of General Internal Medicine, Sunnybrook and Women’s College Health Sciences Centre (J.V.T.), Department of Medicine, University of Toronto (M.K.K., M.M., J.V.T.), and the Department of Public Health Sciences, University of... State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550081, China. College of Resource and Environmental Engineering, Guizhou University, Guiyang 550025, China. School of Information Technology and Electrical Engineering University of Queensland Queensland Australia Key Laboratory of Integrated Regulation and Resource Development on Shallow Lake of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China; College of Environment, Hohai University, Nanjing 210098, China; Department of Engineering, University of Cambridge, Cambridge CB2 1PZ, UK Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, P.R. China.; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, P.R. China. Department of Materials Science and Engineering University of Illinois at Urbana-Champaign USA Maternal and Child Health Hospital of Hunan ProvinceChangsha Hunan China Key Laboratory of Material Chemistry for Energy Conversion and Storage (HUST) of Ministry of Education; School of Chemistry and Chemical Engineering; Huazhong University of Science and Technology (HUST); Wuhan 430074; China School of Materials Science and Engineering, Key Laboratory of Polyphenylene Sulfide Fiber and Application in Textile Industry, State Key Laboratory of New Textile Materials & Advanced Processing Technology and Key Laboratory of Textile Fiber and Products (Ministry of Education), Wuhan Textile University, 430200 Wuhan, P. R. China School of Pharmacy, Anhui Medical University, Hefei, China; Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China; Institute for Liver Disease, Anhui Medical University, Hefei, China National Key Laboratory of Veterinary Public Health Security, Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People’s Republic of China Natural Gas Utilization & Applied Catalysis Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, P. R. China Department of Colorectal Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, 210028 Nanjing, Jiangsu, China; Jiangsu Province Academy of Traditional Chinese Medicine, 210028 Nanjing, Jiangsu, China Division of Endocrinology, Department of Medicine, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, Arkansas 4Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Department of Pediatrics, Second Clinical College, China Medical University, Shenyang 110004, Liaoning, China. [email protected] Institute of Plant Protection and Soil & Fertilizer, Hubei Academy of Agricultural Sciences, Wuhan, Hubei Provience, China; Hubei Key Laboratory of Crop Disease, Insect Pests and Weeds Control, Wuhan, Hubei Province, P. R. China; Key Laboratory of Integrated Pest Management on Crops in Central China, Ministry of Agriculture, Wuhan, Hubei Province, P. R. China Hunan Province Maternal and Children Care Hospital Department of Molecular Oral Medicine and Maxillofacial Surgery, Guanghua College of Stomatology, Sun Yat-Sen University, Guangzhou, China; Oral Growth and Developmental Biology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan Department of Pediatrics , Shengjing Hospital of China Medical University , Shenyang , China Departments of Epidemiology and Health Policy Research, University of Florida, Gainesville, Florida Department of Orthopaedics, Shanghai Jing'an District Zhabei Central Hospital, Shanghai, 200070, China Department of Medical Oncology Second Affiliated Hospital of Nanchang University Nanchang China Key Lab of Organic Optoelectronics & Molecular Engineering Department of Chemistry Tsinghua University Beijing 100084 China Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign; Urbana; USA University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas Center for Cell and Gene Therapy National Joint Engineering Research Center of Energy Saving and Environmental Protection Technology in Metallurgy and Chemical Engineering Industry, Kunming University of Science and Technology, Kunming 650093, China; State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization, Kunming University of Science and Technology, Kunming 650093, China The Department of Orthopedics, The Affiliated Hospital of Beihua University, Jilin, Jilin 132011, P.R. China Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China. CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P.R.China Key Laboratory of Functional Molecular Solids, Ministry of Education, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241002, China College of International Business Shanghai International Studies University Shanghai China; Institute of Linguistics Shanghai International Studies University Shanghai China Heshan Hilly Land Interdisciplinary Experimental Station, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. Department of Endocrinology and Metabolism, Dazhou Central Hospital, Dazhou, Sichuan, China Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China Engineering Research Center for Nanomaterials Henan University Kaifeng China Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX; Ultrasound Department of the Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China. State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization Engineering, Kunming University of Science and Technology, Kunming 650093, China Department of Cardiology, Beijing Hospital, Peking University, Beijing, China; Department of Hematological Oncology, Sun Yat‑sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, P.R. China 1Human Oncology and Departments of; 3Department of Genetics, University of Wisconsin-Madison, Madison, Wisconsin National Engineering Research Center of Electromagnetic Radiation Control Materials, University of Electronic Science and Technology of China, Chengdu, 610054, China; Key Laboratory of Multi-Spectral Absorbing Materials and Structures of Ministry of Education, University of Electronic Science and Technology of China, Chengdu, 610054, China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro‐products, Institute of Virology and Biotechnology Zhejiang Academy of Agricultural Sciences Hangzhou China Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850, China Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA Department of Chemistry, Washington State University, Pullman, Washington 99164, and Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710 Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, P.R. China Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China, and Shanghai Key Laboratory of Molecular Catalysts and Innovative Materials, Department of Chemistry, Fudan University, Shanghai 200433, China School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA Special Inspection Department Shaoxing City Keqiao District Hospital of traditional Chinese Medicine Shaoxing China Department of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Department of Pharmacology, Toxicology and Therapeutics University of Kansas Medical Center Kansas City KS USA; Department of Toxicology School of Public Health Anhui Medical University Hefei China Institute of Preventive Genomic Medicine, School of Life Sciences, Northwest University , Xi’an 710069 , China; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University , Xi’an 710069 , China Department of ICU, Wujin People Hospital Affiliated with Jiangsu University and Wujin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, PR China. Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China Hematological Oncology; State Key Laboratory of Oncology in South China, Guangzhou, China Department of Basic Science of Stomatology, Affiliated Hospital of Stomatology Nanjing Medical University Nanjing China; Jiangsu Key Laboratory of Oral Diseases Nanjing Medical University Nanjing China Department of Orthopedics, The First Affiliated Hospital of Guangdong Pharmaceutical University Guangdong Pharmaceutical University Guangzhou Guangdong China Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, China. Eye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China Department of Cardiovascular Medicine Wuhan Third Hospital & Tongren Hospital of Wuhan University Wuhan Hubei China The Key Laboratory of Life-Organic Analysis; Qufu Normal University; Qufu 273165, China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine; Qufu Normal University Department of Chemistry and Physics; Louisiana State University Shreveport; USA Hebei University of Chinese Medicine, Department of Preventive Medicine, Shijiazhuang, Hebei, China Hua Wang is with the Department of Communication and the Department of Community Health and Health Behavior, University at Buffalo, The State University of New York. Arvind Singhal is with the Department of Communication, The University of Texas at El Paso, and the Faculty of Business Administration, Hedmark University College, Rena, Norway. School of Life Science, Huzhou University, Huzhou, 313000, PR China Laboratory of Functional Molecular Solids, Ministry of Education; Anhui Key Laboratory of Molecular-Based Materials, School of Chemistry and Materials Science, Anhui Normal University Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, China. [email protected]. Shandong Provincial Key Laboratory of Life-Organic Analysis; College of Chemistry and Chemical Engineering; Qufu Normal University; Qufu; China Department of Oral and Maxillofacial Surgery Guanghua School of Stomotology Sun Yat‐sen University Guangzhou China Hainan Provincial Key Laboratory of Tropical Medicine Hainan Medical College Haikou China Department of Oncology Jiangxi Key Laboratory of Clinical and Translational Cancer Research The Second Affiliated Hospital of Nanchang University Nanchang China; Department of Oncology The Second Affiliated Hospital of Nanchang University Nanchang China Department of Gynecological Oncology, Zhongnan Hospital Wuhan University Wuhan People's Republic of China; Hubei Key Laboratory of Tumor Biological Behavior Wuhan People's Republic of China; Hubei Clinical Cancer Study Center Wuhan People's Republic of China Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China Hunan Maternal and Child Health Care Hospital; Changsha Hunan China Department of Dermatology, Children’s Hospital of Chongqing Medical University, Chongqing, China, School of Pharmacy Shanxi Medical University Taiyuan 030001 P. R. China Department of Pediatric, Shengjing Hospital of China Medical University, Shenyang 110004, China University of Southern California, Annenberg School for Communication, Los Angeles, California. Key Laboratory of Luminescence Analysis and Molecular Sensing Ministry of Education, College of Chemistry and Chemical Engineering Southwest University Chongqing 400715 P. R. China Department of Orthopedics, The First Hospital Affiliated to Soochow University, Suzhou, Jiangsu 215006, P.R. China Université de Toulouse, Institut National Polytechnique - Ecole Nationale Superieure Agronomique Toulouse, Génomique et Biotechnologie des Fruits, Castanet-Tolosan F-31326, France; Institut National de la Recherche Agronomique, Génomique et Biotechnologie des Fruits, Chemin de Borde Rouge, Castanet-Tolosan, F-31326, France Celgene Corporation, Warren, New Jersey 07059, and Department of Cellular Immunology, The Rockefeller University, New York, New York 10021 Department of Chemistry, School of Pharmacy, Air Force Medical University, Xi’an, Shaanxi 710032, People’s Republic of China Department of Cardiology, West China Hospital of Sichuan University Chengdu 610041, China. Department and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China Genentech Inc. South San Francisco California Department of Dermatology, No.1 Hospital of China Medical University, Shenyang, China Contribution from the Department of Chemistry, University of Nebraska, Lincoln, Nebraska 68588-0304, and X-ray Crystallographic Laboratory, Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455 Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148; School of Business & Law, Foshan University 3 , Foshan 528000, China; School of Mechanical Engineering, Dongguan University of Technology, Dongguan 523000, China 4 Department of Ultrasound, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China Department of Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China Department of Molecular Medicine The Scripps Research Institute La Jolla, CA 92037 USA School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China Department of Cardiology, Beijing Hospital, Beijing 100730, China. Department of Pathology University of Washington School of Medicine Seattle WA USA; DANDRITE‐Danish Research Institute of Translational Neuroscience & Department of Biomedicine University of Aarhus Aarhus Denmark Division of Endocrinology and Metabolism (H.W., Z.Z., W.C., T.H., J.J.C., S.C.E.), Department of Internal Medicine, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 Department of Ophthalmology, Hunan People's Hospital, Changsha 410005, China. [email protected] School of Life Science, Huzhou University, Huzhou 313000, China Department of Orthopaedics, First Affiliated Hospital of Sun Yat-sen University 58 Zhongshan Second Road, Guangzhou, P. R. China. Department of Medical Genetics Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China; National Health Commission Key Laboratory of Birth Defects Research Prevention and Treatment Changsha Hunan China Space Engineering University Laboratory of Liver Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Bethesda MD; Institute for Liver Diseases, Anhui Medical University, Hefei, Anhui Province; P.R. China Key Laboratory of Recycling and Eco-treatment of Waste Biomass of Zhejiang Province; Zhejiang University of Science and Technology; Hangzhou 310023; China; School of Civil Engineering and Architecture Department of Dentistry, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, 1304 West Green Street, Urbana, Illinois 61801, United States *Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030; and Key Laboratory of Phytochemical R&D of Hunan Province; Hunan Normal University; Changsha 410081, China; Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research; Ministry of Education Jiangsu Center for Disease Control and Prevention, Nanjing, People's Republic of China; Department of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China Key Lab for Special Functional Materials of Ministry of Education, Henan University, Kaifeng, 475004, China, College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang, 471022, China, and Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China School of Textiles and Garments Southwest University Chongqing China Anhui Laboratory of Molecule-Based Materials; The Key Laboratory of Functional Molecular Solids, Ministry of Education; School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, China Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People’s Republic of China Department of Toxicology, School of Public Health, Anhui Medical University, Hefei 230032, China Departments of Nuclear Medicine and Cardiology, Beijing Hospital, Beijing 100730, China. Email: [email protected]. Department of Surgery, Chengdu General Hospital of Chengdu Military Region Chengdu, China ; Kunming General Hospital of Chengdu Military Region Kunming, Yunnan, 650000, China. Frontier Institute of Science and Technology, and State Key Laboratory for Mechanical Behavior of Materials, Xi’an Jiaotong University, Xi’an 710049, People’s Republic of China Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892; From the Department of Bioengineering (C.B.R., N.N.D., S.M.D., J.A.B.), Gorman Cardiovascular Research Group, Department of Surgery (M.E.L., S.T., T.T., T.K., J.S.A., J.H.G., R.C.G.), and Department of Radiology (W.R.T.W., J.J.P.), University of Pennsylvania, Philadelphia; and Department of Mechanical Engineering (H.W., J.F.W.) and Department of Surgery (J.F.W.), University of Kentucky, Lexington. Department of Oral and Maxillofacial Surgery, Guanghua School of Stomotology, Hospital of Stomotology, Sun Yat-sen University, People's Republic of China Department of Respiratory Medicine, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Zhejiang University School of Medicine, Shaoxing, Zhejiang 312000, P.R. China Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering Shandong University Jinan 250100 People's Republic of China Department of Acupuncture & Orthopedics, Hubei College of TCM, Wuhan 430061, China. [email protected] Pacific Norwest National Laboratory, Richland, Washington 99352 College of Chemistry and Materials science; Sichuan Normal University; Chengdu 610066; China Key Laboratory of Life-Organic Analysis, School of Chemistry and Chemical Engineering, Qufu Normal University; 57 Jingxuan West Road Qufu Shandong 273165 China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University; 57 Jingxuan West Road Qufu Shandong 273165 China [email protected] Department of Health Outcomes and Policy, University of Florida, USA Georgia Institute of Technology Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China; Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of the Ministry of Education, Sichuan University, Chengdu, Sichuan 610041, China Hubei Key Laboratory for New Textile Materials and Applications and State Key Laboratory of New Textile Materials & Advanced Processing Technology, School of Materials Science and Engineering, Wuhan Textile University, Wuhan 430200, P. R. China Tumor Microenvironment and Metastasis Section, The Hormel Institute University of Minnesota Austin MN USA Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, China; Institute for Liver Diseases of Anhui Medical University, Hefei 230032, Anhui, China Engineering Research Center for Nanomaterials, Henan University, Kaifeng 475004, P.R. China Ultrasonic Department, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China Department of Medical Genetics & the Prenatal Diagnosis Center of Hunan Province Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China; NHC Key Laboratory of Birth Defects for Research and Prevention Hunan Provincial Maternal and Child Health Care Hospital Changsha Hunan China Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China Graduate School of Peking Union Medical College Chinese Academy of Medical Science Peking Union Medical College Beijing China; Institute of Clinical Medical Sciences China‐Japan Friendship Hospital Beijing China Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming 650093, China; State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization, Kunming University of Science and Technology, Kunming 650093, China Engineering Research Center of Shellfish Culture and Breeding in Liaoning Province, School of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China College of Materials Science and Engineering, Hubei Provincial Engineering Center of Industrial Fiber Preparation and Application, Wuhan Textile University, Wuhan 430200, Hubei China CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 P.R. China The Key Laboratory of Functional Molecular Solids; Ministry of Education; School of Chemistry and Materials Science; Anhui Normal University; Wuhu; China Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism,National Institutes of Health,Bethesda,MD; Institute for Liver Diseases,Anhui Medical University,Hefei,China Division of Microbiology, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA Department of Endocrinology East Hospital Tongji University School of Medicine Shanghai China Department of ICU, Wujin People Hospital Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, China College of Material Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, China; State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences 116023 Dalian China Department of Medical Genetics Maternal and Child Health Hospital of Hunan Province Changsha China; National Health Commission Key Laboratory of Birth Defects Research, Prevention and Treatment Hunan Provincial Maternal and Child Health Care Hospital Changsha China Institute of Plant Protection and Soil Fertilizer, Hubei Academy of Agricultural Sciences, Wuhan, Hubei, China; Key Laboratory of Integrated Pest Management on Crops in Central China, Ministry of Agriculture, Wuhan, Hubei, China; Hubei Key Laboratory of Crop Disease, Insect Pests and Weeds Control, Wuhan, Hubei, China Department of Dermatology Children's Hospital of Chongqing Medical University Chongqing China; Key Laboratory of Child Development and Disorders Ministry of Education Chongqing China †Department of Toxicology, Anhui Medical University, Hefei 230032, China;; ‡Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Anhui Medical University, Hefei 230032, China; and Department of Endocrinology, the Affiliated East Hospital, Tongji University, Shanghai, China Division of Physical Biology; Bioimaging Center; Shanghai Synchrotron Radiation Facility; Shanghai Institute of Applied Physics; Chinese Academy of Sciences Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40506-0503 Department of Obstetrics and Gynecology, Taizhou Hospital of Chinese Traditional Medicine, Taizhou, China; Department of Chemistry and Physics, Louisiana State University, Shreveport, Louisiana 71115, United States Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; Department of Physiology and Neurobiology, Medical College of Soochow University, Suzhou, People’s Republic of China Key Laboratory of Interface Science and Engineering in Advanced Materials of Ministry of Education Taiyuan University of Technology NO.79, Yingze West Main Street Taiyuan Shanxi 030024 P. R. China Department of Medicine, University of Kuopio, Kuopio, Finland Authors' Affiliations: Departments of 1Pathology, 2Gastrointestinal Medical Oncology, and 3Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and 4Institute of Occupational Medicine and the MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College Huazhong University of Science & Technology, Wuhan, China Department of Gastroenterology Xi'an Children's Hospital Xi'an China Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. [email protected] Department of Toxicology, Anhui Medical University, Hefei 230032, China Department of Chemical and Biomolecular Engineering, The University of Akron, Akron, Ohio 44325, United States Chinese Academy of Sciences State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, , Dalian, Liaoning 116023, People’s Republic of China Department of Toxicology (X.-J.L., B.-W.W., C.Z., Y.-H.C., C.-Q.H., H.W., D.-X.X.), Anhui Medical University, Hefei, China, 230032;; Anhui Provincial Key Laboratory of Population Health and Aristogenics (X.-J.L., Y.-H.C., H.W., D.-X.X.), Hefei, China, 230032; National Laboratory of Plant Molecular Genetics Shanghai Institute of Plant Physiology and Ecology Chinese Academy of Sciences 300 Fenglin Road Shanghai 200032 China School of Biological Science and Medical Engineering, Beihang University, Beijing; Hefei Innovation Research Institute, Beihang University, Hefei Siping Community Health Service Center of Yangpu District, Shanghai, China. Department of Oncology First Affiliated Hospital of Anhui Medical University Hefei Anhui 230022 P. R. China Department of Dermatology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics Chongqing China Department of Radiation Oncology Second Affiliated Hospital of Nanchang University Nanchang China Center for Disease Prevention and Control Jiangsu Province China Department of Chemistry, Washington State University, Pullman, Washington 99164 [email protected] Department of Lymphoma and Myeloma, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX; The School of Electrical and Computer Engineering; Georgia Institute of Technology; Atlanta; USA Division of Endocrinology, Department of Medicine, Central Arkansas Veterans Healthcare System and University of Arkansas for Medical Sciences, Salt Lake City, Utah Acupuncture‑Moxibustion and Orthopedic College, Hubei University of Chinese Medicine, Wuhan, Hubei 430061, P.R. China Department of Gene Regulation, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan Department of Laboratory Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People’s Republic of China Department of Infectious Diseases Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan China; Joint International Laboratory of Infection and Immunity Huazhong University of Science and Technology Wuhan China Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; Division of Neonatology, Rainbow Babies & Children's Hospital and Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio; School of Chemistry Beijing Advanced Innovation Center for Biomedical Engineering Beihang University Beijing 100191 P. R. China Key Laboratory of Tropical Translational Medicine of Ministry of Education & Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical University, Haikou Shandong Province Key Laboratory of Life-Organic Analysis; School of Chemistry and Chemical Engineering; Qufu Normal University; Qufu City 273165, P. R. China Department of NICU, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China Department of Bone and Joint, Shenzhen People’s Hospital, 2nd Clinical Medical College of Jinan University, Shenzhen 518020, China Department of Toxicology, School of Public Health; Center for Big Data and Population Health of IHM; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes; MOE Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Hefei 230032, China CAS Key Laboratory of Colloid; Interface and Chemical Thermodynamics; CAS Research/Education Center for Excellence in Molecular Sciences; Institute of Chemistry; Chinese Academy of Sciences Hunan Provincial Maternal and Child Health Hospital, Hunan, China Laboratory of Functional Molecular Solids; Ministry of Education; Anhui Laboratory of Molecule-Based Materials (State Key Laboratory Cultivation Base); School of Chemistry and Materials Science; Anhui Normal University Department of Ultrasonography Luoyang Central Hospital Affiliated to Zhengzhou University Luoyang City Henan Province China School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, China College of Veterinary Medicine Gansu Agricultural University Lanzhou China; Key Laboratory of Animal Reproductive Physiology and Reproductive Regulation of Gansu Province Lanzhou China Beijing Key Laboratory for Radiobiology Beijing Institute of Radiation Medicine Beijing China Department of Hematology Lymphoma Research Center Peking University Third Hospital Beijing China The Department of Orthopedic, The Affiliated Hospital of Beihua University, Jilin 132011, PR China. Department of ICU, Wujin People Hospital, the Affiliated Hospital of Jiangsu University, Changzhou Faculty of Life Science, Northwestern Polytechnical University, Xian, Shanxi, P.R. China. Yancheng Normal University, Yancheng, Jiangsu 224000, China Harvard John A. Paulson School of Engineering and Applied Sciences; Harvard University; Cambridge; Massachusetts 02138; USA State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University Institute of Stomatology, Nanjing Medical University & Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China. School of Materials Science and Engineering Nanyang Technological University Nanyang Avenue 639798 Singapore Department of Pharmaceutical Analysis; School of Pharmacy; Shenyang Pharmaceutical University; Shenyang 110016; China College of Veterinary Medicine Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation Gansu Agricultural University Lanzhou China Department of Chemistry, School of Pharmacy, Air Force Medical University, Xi'an 710032, P.R.China Hebei Medical University; 361 East Zhongshan Road Shijiazhuang 050017 Hebei China Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. State Key Laboratory of Complex Nonferrous Metal Resources Clean Utilization, Kunming University of Science and Technology, Kunming 650093, China State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, P. R. China Department of Paediatric Ophthalmology and Otorhinolaryngology, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, China Department of Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Department of Electrical Engineering and Computer Science, Colorado School of Mines, Golden, CO, USA. Key Lab of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University, Beijing 100084, China Departments of †Nutrition, ‡Chemistry, and §Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States Department of Chemistry University of Science and Technology of China Hefei Anhui 230026 China Department of Dermatology, Children’s Hospital of Chong Qing Medical University, Chong Qing, China Key Laboratory of Functional Molecular Solids; Ministry of Education; Anhui Laboratory of Molecule-Based Materials; College of Chemistry and Materials Science; Anhui Normal University |
Showing number of triples: 1 to 1000 of 4878.
Next Page | Last Page |