http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_a3da5f6c2eb43a757efc0bf76d194116
Outgoing Links
Predicate | Object |
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family-name | Li Huang Huang |
name | Li Huang |
given-name | Li |
organization-name | School of Nursing, Anhui University of Chinese Medicine, No. 103 of Middle Meishan Road, Hefei, Anhui, China Department of Pediatrics Zhongda Hospital Southeast University Nanjing China; Teaching and Research Section of Pediatrics Medical College Southeast University Nanjing China Department of Postgraduate, Jiangxi University of Chinese Medicine, Nanchang 330004, China Academy of Arts and Design, Tsinghua University, Beijing, 10084, China; The Future Laboratory, Tsinghua University, Beijing, 10084, China Medical Department of Graduate School of Nanchang University, Nanchang Jiangxi, China National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China, and State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan 430062, China Department of Physics, Southern University of Science and Technology, Shenzhen 518005, People’s Republic of China Lanzhou Railway Design Institute Company Limited, Lanzhou 730000, China. Institute of Neurobiology and Department of Human Anatomy & Histoembriology, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an, Shanxi, People Republic of China; Taihe Hospital Affiliated to Hubei Medical College, Shiyan, Hubei, People Republic of China Experimental Animal Research center, Guangzhou Medical College, China Weihai Marine Organism & Medical Technology Research Institute, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, P. R. China Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, 510630, China; Institute of Molecular and Functional Imaging, Jinan University, Guangzhou, 510630, China State Key Laboratory of Bioelectronics; National Demonstration Center for Experimental Biomedical Engineering Education; School of Biological Science and Medical Engineering; Southeast University; Nanjing 210096 State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Chaoyang District, Beijing 100101, China La Jolla Pharmaceutical Company, 6455 Nancy Ridge Drive, San Diego, California 92121 Shanghai Key Laboratory of Regulatory Biology Institute of Biomedical Sciences and School of Life Sciences East China Normal University Shanghai China Department of Pancreatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080,China The Third People’s Hospital of Chengdu, Affiliated Hospital of Southwest Jiao Tong University Medical School, Chengdu, China; Department of Clinical Medicine, Southwest Medical University, Luzhou, China Department of Biology, Guiyang Medical University, Guiyang 550004, China. Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China Department of Cardiology, Guangdong Cardiovascular Institute Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangdong China Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong 999077, China. National Synchrotron Radiation Laboratory; University of Science and Technology of China; Hefei 230029; P. R. China Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710 MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 PR China State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resources and Environmental Engineering, East China university of Science and Technology, Shanghai 200237, China Department of Rheumatology, Xiangya Hospital, Central South University, Changsha, Hunan, China; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, Hunan, China; Sepsis Translational Medicine Key Laboratory of Hunan, Central South University, Changsha, Hunan, China Department of Internal Medicine, Division of Geriatric Medicine, Institute of Gerontology, Geriatric Research Education and Clinical Center, Veterans Administration Medical Center, University of Michigan , Ann Arbor Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou City, Fujian Province, China Cancer Centers from Renmin Hospital of Wuhan University and The People's Hospital of Guangxi Autonomous Region, China; [email protected], [email protected]. Institute of Physics and University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190, China Department of Animal Biology, University of Pennsylvania, Philadelphia, PA 19104 The Second District of Tumor, Henan Province Hospital of TCM, Zhengzhou 450000, China. *Corresponding author, E-mail: [email protected]. Department of Rheumatology and Immunology, First People's Hospital of Jingzhou, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei 434000, P.R. China Tianjin Key Laboratory of Low Dimensional Materials Physics and Preparation Technology, School of Science, Tianjin University, Tianjin 300354, China College of Materials Science and Engineering, Nanjing Tech University, Nanjing 210009, China; Yangtze Delta Region Institute of Advanced Materials, Suzhou 215133, China Institute of Physics & University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, 100190, P. R. China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China Department of Stomatology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China Department of Rehabilitation Medicine, The Third Affiliated Hospital, Sun Yat-sen Univerity, Guangzhou, China Center of Pulmonary Vascular Disease State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Chaoyang District, Beijing, PR China Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. Institute of Physics, Chinese Academy of Sciences, Beijing 100190, P.R. China Department of Chemistry, Michigan State University, East Lansing, Michigan 48824 Department of Pulmonology, Children's Hospital, Soochow University, Suzhou 215003, China. Authors' Affiliations: Departments of 1Cancer Biology and 2Urology, The University of Texas at MD Anderson Cancer Center, Houston, Texas; and the 3Tumor and Metastasis Program, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan Key Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences Wuhan 430062 China Authors' Affiliations: 1Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and 2Department of Dermatology, Boston University School of Medicine, Boston Medical Center, Boston, Massachusetts Outpatient Department of Sichuan Orthopedic Hospital Department of Electrical and Computer Engineering National University of Singapore 4 Engineering Drive 3 Singapore 117583 Singapore; Centre for Advanced 2D Materials National University of Singapore 6 Science Drive 2 Singapore 117543 Singapore Operation Center Zigong Fourth People's Hospital Zigong China Management and Organizations, Kellogg School of Management, Northwestern University Department of Geriatric Intensive Care Unit Nursing, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China; Sichuan Translational Medicine Research Hospital, Chinese Academy of Sciences, Chengdu 610072, China Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei Anhui 230029 China State Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China; College of Life Sciences University of Chinese Academy of Sciences Beijing China Institute of Physics and University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190, P.R. China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China Department of Plant Sciences, University of Idaho , Moscow, Idaho, 83844 , USA Department of Radiology First Affiliated Hospital of Sun Yat‐Sen University Guangzhou P.R. China Nursing School Anhui University of Chinese Medicine Hefei China Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Chongqing Key Laboratory of Nutrition and Food Safety, Chongqing Medical Nutrition Research Center, Chongqing, People’s Republic of China Department of Hematology, Jinhua People’s Hospital , No. 228 Xinhua Street , Jinhua , Zhejiang, 32100 , China Department of Pharmacology, School of Pharmacy, Xuzhou Medical College, Tongshan Road 209, Xuzhou 221004, China Oil Crops Research Institute Chinese Academy of Agricultural Sciences/Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of Agriculture Wuhan Hubei P.R. China Institute of Light Industry and Food Engineering Guangxi University Nanning China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China Beijing National Center for Condensed Matter Physics and Institute of Physics Chinese Academy of Sciences 100190 Beijing China; School of Physical Sciences University of Chinese Academy of Sciences 100190 Beijing China Lanzhou Railway Design Institute Co., Ltd., Lanzhou 730000, China. Guangxi Key Laboratory of Animal Vaccines and Diagnostics Guangxi Veterinary Research Institute Nanning Guangxi China School of Life Sciences, East China Normal University, Shanghai, China; Suzhou Industrial Park Xingyang School, Suzhou, China Department of Rheumatology, Xiangya Hospital, Central South University, Changsha City, Hunan; Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha City, Hunan, PR China. Huangshi TCM Hospital, Huangshi 435000, Hubei, China; [email protected]. Jiangsu Key Laboratory of Translational Research and Therapy for Neuro‐Psycho‐Diseases College of Pharmaceutical Sciences Soochow University Suzhou 215123 China Department of Biliary and Pancreatic Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China Department of Rehabilitation Medicine The Third Affiliated Hospital of Sun Yat‐sen University Guangzhou China Department of Neurology, Xiangyang No.1 People's Hospital Hubei University of Medicine Xiangyang China Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, P. R. China Statistics and Data Center, Children's Oncology Group, Monrovia, CA Cancer Center, Renmin Hospital of Wuhan University, People's Hospital of Guangxi Autonomous Region, China; [email protected], [email protected]. Institute of Cardiovascular Research; Luzhou Medical College; Luzhou China Sichuan University National Clinical Research Center for Geriatrics, West China Hospital, , Chengdu, Sichuan, China Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning city, China Department of Physics; Southern University of Science and Technology; Shenzhen; China College of Chemistry and Chemical Engineering, Central South University, Changsha, P. R. China Department of Pancreato‐Biliary Surgery First Affiliated Hospital, Sun Yat‐Sen University Guangzhou PR China The Future Laboratory, Tsinghua University , Beijing 100084 , China Institute of Molecular and Functional Imaging, Jinan University, Guangzhou, China Key Laboratory of Bio‐Resource and Eco‐Environment of Ministry of Education College of Life Sciences Sichuan University Chengdu China Department of Pancreatobiliary Surgery First Affiliated Hospital of Sun Yat‐Sen University Guangzhou 510080 China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety and the Ministry of Education (MOE) Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College Huazhong University of Science and Technology Wuhan China Business Analytics Centre National University of Singapore Singapore Singapore Authors' Affiliations: 1State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing; 2Institute of Cancer Stem Cell, Dalian Medical University Cancer Center, Dalian; 3Laboratory of Tumor and Molecular Biology, Beijing Institute of Biotechnology, Beijing; 4College of Biological Sciences, China Agricultural University, Beijing; 5College of Life Science, University of Science and Technology of China, Hefei; 6Department of Dermatology, Xiangya Hospital of China South University, Changsha; 7The Chinese Hippo Consortium, China; and 8Biological Sciences, The University of Chicago, Chicago, Illinois Healthtimegene Institute, Shenzhen, China Hematological Department Hainan General Hospital Hainan Affiliated Hospital of Hainan Medical University Haikou China Research Center for Nutrition and Food Safety Chongqing Key Laboratory of Nutrition and Food Safety Institute of Military Preventive Medicine Third Military Medical University Chongqing 400038 P. R. China Department of Hematology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China State Key Laboratory of Tribology Tsinghua University Beijing 100084 China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety and the Ministry of Education (MOE) Key Lab of Environment and Health, School of Public Health, Tongji Medical College Huazhong University of Science and Technology 13 Hangkong Road Wuhan Hubei 430030 China Department of Intensive Care Unit, Suizhou Hospital, Hubei University of Medicine, Suizhou, Hubei Province, China Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People’s Republic of China, Chengdu, China; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, China; International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province, Chengdu, China; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China; College of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu, China Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Tübingen, Germany; Institute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China State Key Laboratory of Biotherapy and Cancer Center West China Hospital Sichuan University, and Collaborative Innovation Center for Biotherapy Chengdu 610041 China Department of Neurology, Hainan General Hospital, Haikou 570311, Hainan Province, China. Guangzhou Women and Children's Medical Center Affiliated to Guangzhou Medical University Guangzhou Guangdong China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Chaoyang District, Beijing 100101, People's Republic of China Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People’s Republic of China State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, PR China Institute for Diabetes, Obesity, Metabolism,; Department of Cell and Developmental Biology, and China-Japan Friendship Hospital, Beijing, China. Department of Chemical Engineering, Hunan University, Changsha 410082, China State Key Laboratory of Bioelectronics; School of Biological Science and Medical Engineering; Southeast University; Nanjing 210096; China Department of Ultrasonic Diagnosis, Shanghai Ruijin Rehabilitation Hospital, China Department of Toxicology School of Public Health Medical College of Soochow University Suzhou Jiangsu China Fibrosis Biology Drug Discovery, Bristol-Myers Squibb, Lawrenceville, New Jersey; and From the Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, P.R. China (Q.L., S.X., X. Chen, X. Zhang, X.L., L.L., D.G., M.W., S.Y., X. Cao, T.T., W.H., J.G., L. Huang, R.C., X. Zhou, W.C., T.X., Q.G., Y.W., M.H., X.W., G.Z., Y.Z., C.Z., X.Y., L. Hao, Nianhong Yang) Department of Physics, Southern University of Science and Technology, Shenzhen 518055, P. R. China Industrial Crops Institute, Hubei Academy of Agricultural Sciences, Wuhan 430070, China *Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China; and Department of Hematology Jinhua People's Hospital Jinhua Zhejiang China College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, P. R. China and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, 730000, Lanzhou, P. R. China Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, United States Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China School of Software, Shandong University, Ji'nan, China Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China Department of Haematology, West China Hospital Sichuan University Chengdu Sichuan Province China Authors' Affiliations: Departments of 1Gynecologic Oncology and Reproductive Medicine, 2Hematology and Oncology, 3Biostatistics, 4Cancer Biology, and 5Pathology, and 6The Center for RNA Interference and Non-Coding RNAs; The University of Texas MD Anderson Cancer Center, Houston, Texas Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, China Department of Physics & Academy for Advanced Interdisciplinary Studies Southern University of Science & Technology Shenzhen Guangdong 518055 China; Quantum Science Center of Guangdong‐Hongkong‐Macao Greater Bay Area Shenzhen Guangdong 518055 China Children's Oncology Group Statistical Center Arcadia California Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Hangzhou, China; Institute of Laboratory Medicine, Zhejiang University, Hangzhou, China Institute of Cardiovascular Research, Sichuan Medical University, Luzhou, China Department of Hepatobiliary Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. Centre for Health Policy Department of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China School of Public Health, Fudan University, Shanghai, China. Department of Obstetrics and Gynecology, Xishui Hospital, Affiliated to Hubei Institute of Science and Technology, China The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, PR China. Department of Plant Sciences, University of Idaho, Moscow, ID, USA Wheat Genetic and Genomic Resources Center, Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506–5502 Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University , Guangzhou, Guangdong, P. R. China Department of Histology and Embryology, School of Basic Medical Sciences Capital Medical University Beijing China Center for Reproductive Medicine, Guangdong Women and Children Hospital , Guangzhou 511400, Guangdong Province , China Department of Toxicology College of Public Health, Zhengzhou University Zhengzhou China Department of Cardiovascular Surgery, the Second Affiliated Hospital of Nanchang University, Nanchang, China National Integrative Medicine Center for Cardiovascular Diseases, China-Japan Friendship Hospital, Beijing 100029, China Zhejiang University Laboratory of Cell & Molecular Biology, Institute of Vegetable Science, , Hangzhou 310058, China Department of Physics, South University of Science and Technology of China, Shenzhen 518005, P. R. China National Base for International Science & Technology Cooperation, School of Chemistry, Xiangtan University, Xiangtan 411105, China Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China Fujian University of Technology Department of Infectious Diseases, The People’s Hospital of Yubei District of Chongqing City, Chongqing, China Department of Physics, South University of Science and Technology of China, Shenzhen, Guangdong 518055, China; Ames Laboratory, U.S. Department of Energy and Department of Physics and Astronomy, Iowa State University, Ames, Iowa 50011, United States Department of Biotechnology, Guangxi Key Laboratory of Animal Vaccines and Diagnostics, Guangxi Veterinary Research Institute, Nanning, Guangxi, China Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China The Affiliated Jinhua Hospital of Wenzhou Medical University, Zhejiang 321099, People’s Republic of China Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States 5State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, Guangdong, China Department of Internal Medicine, Texas A & M Health Science Center College of Medicine,; Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China; Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China State Key Laboratory of Magnetism Institute of Physics Chinese Academy of Sciences Beijing 100190 China Department of Chemistry and Chemical Engineering, Guangxi University, Nanning, Daxue Road, 88, 530004, People's Republic of China. Institute of Neuroscience and Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, Henan 466001, China Department of Radiation Oncology, Peking University 3rd Hospital, Haidian District, Beijing 100191, China Department of Radiology, The Frist Affiliated Hospital, Jinan University, Guangzhou, Guangdong, 510630, P.R.China. [email protected] Department of Toxicology Zhengzhou University School of Public Health Zhengzhou Henan China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Chaoyang District, Beijing, China Department of Hematology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou City, Hainan, China Department of General Surgery Shanghai General Hospital Shanghai Jiao Tong University Shanghai P. R. China Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China National Synchrotron Radiation Laboratory; University of Science and Technology of China; Hefei; China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing , China 5College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, PR China; 1State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China Department of Physics Southern University of Science and Technology Shenzhen 518055 China Stony Brook University Hospital, Stony Brook, NY Department of Otolaryngology‐Head and Neck Surgery The Second Xiangya Hospital, Central South University Changsha China Centre for Health Policy, University of Melbourne, Parkville, Victoria, Australia. Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine Guangdong Pharmaceutical University Guangzhou People's Republic of China; School of Traditional Chinese Medicine Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center Guangzhou People's Republic of China Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Wadsworth Center, New York State Department of Health and Department of Environmental Health Sciences, State University of New York, Albany, New York 12201-0509, United States Department of Emergency Intensive Care Unit, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China Institute of Preventive Veterinary Medicine, College of Veterinary Medicine of Sichuan Agricultural University, Chengdu, Sichuan, People’s Republic of China; Research Centre of Avian Disease, College of Veterinary Medicine of Sichuan Agricultural University, Chengdu, Sichuan, People’s Republic of China; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, Sichuan, People’s Republic of China Wadsworth Center, New York State Department of Health, Department of Environmental Health Sciences, SUNY-Albany, Albany, New York 12201, United States National Clinical Research Center of Kidney Diseases JinLing Hospital, Nanjing University School of Medicine Nanjing China Academy of Arts and Design, Tsinghua University , Beijing, 10084 , China; The Future Laboratory, Tsinghua University , Beijing, 10084 , China Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University Haikou 570311, Hainan, China. School of Electronics and Information Engineering Hebei University of Technology Tianjin P. R. China Research Group of HIV Molecular Epidemiology and Virology Center for Emerging Infectious Diseases The State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Wuhan China Li Huang, Gabriel Frampton, Sharon DeMorrow, Department of Internal Medicine, Texas A&M Health Science Center College of Medicine, Temple, TX 76504, United States. Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China. Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science; College of Chemistry and Chemical Engineering; Central South University; Changsha; P. R. China Children’s Oncology Group, Monrovia, CA Department of Ophthalmology, Fujian Medical University Union Hospital, 29 Xinquan Road, Gulou District, Fuzhou 350001, China; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China Department of Oncology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China JR Laboratories Inc., #12-3871 North Fraser Way, Burnaby, BC, Canada, V5J 5G6 Pharmaceutical Research Institute, Wuhan Institute of Technology, Wuhan 430205, China; School of Chemical Engineering & Pharmacy, Wuhan Institute of Technology, Wuhan 430205, China Institute of Physics & University of Chinese Academy of Sciences; Chinese Academy of Sciences; Beijing 100190; China Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA Department of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China National Laboratory of Biomacromolecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing China Prenatal Diagnostic Centre and Cord Blood Bank, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China; Institute of Drug Clinical Trial, Affiliated Taihe Hospital of Hubei University of Medicine, Shiyan, Hubei, China Department of Anesthesiology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China; Institute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China; Key Laboratory of Anesthesiology and Resuscitation (Huazhong University of Science and Technology), Ministry of Education Wuhan China Medical Imaging Center First Affiliated Hospital of Jinan University Guangzhou China Authors' Affiliations: 1The Institute of Cardiovascular Sciences and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Peking University Health Science Center; 2The Department of Cardiovascular Medicine and the Department of Endocrinology, the Military General Hospital of Beijing; 3The Department of Cardiovascular Medicine, China-Japan Friendship Hospital; and 4Department of Hepatobiliary Surgery, West Campus, Beijing Chao-yang Hospital Affiliated to Capital Medical University, Beijing, China Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China;; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Department of Rehabilitation Medicine, Foresea Life Insurance Guangzhou General Hospital, Guangzhou City, Guangdong Province State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People's Republic of China Department of Physics, Sichuan University, Chengdu 610064, China Key Laboratory of Mesoscopic Chemistry, College of Chemistry and Chemistry Engineering, Eco-materials and Renewable Energy Research Center, and School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China Center for Advanced Energy and Functional Materials, School of Materials Science and Engineering, Fujian University of Technology, Fuzhou 350118, China 1Institute of Neuroscience and Translational Medicine, College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, Henan, China State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou, China From the Department of Epidemiology and Preventive Medicine, Monash Center of Cardiovascular Research and Education in Therapeutics, Monash University, Alfred Hospital, Melbourne, Australia (T.G.v.L., B.H.W., A.R.K., L.H., H.K.); Department of Cardiology B, Oslo University Hospital Ullevål, Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway (T.G.v.L., D.A.); Department of Medicine, University of Melbourne, St Vincent’s Hospital, Fitzroy, Australia (A.R.K.);... 2Oncology, and The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 111 Dade Road, Guangzhou 510120, China Department of Hematology, People's Hospital of Hainan Province, Haikou 570311, Hainan Province, China. Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Centre for Health Policy, University of Melbourne, Melbourne, VIC, Australia Obstetric and Gynecological Hospital of Fudan University, Shanghai, People's Republic of China Department of Laboratory Medicine First Affiliated Hospital of Guangxi Medical University Nanning China Department of Anesthesiology Lu'an Hospital Affiliated to Anhui Medical University Lu'an China Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of Agriculture Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences Wuhan China; National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University Wuhan China Department of Physics, Southern University of Science and Technology, Shenzhen 518005, China Department of Brain Disease, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China Department of Pulmonology, Children's Hospital Affiliated to Soochow University, Suzhou 215003, China. From the Department of Pathology, Louisiana State University Health Sciences Center, New Orleans Center for Reproductive Medicine, Guangdong Women and Children Hospital, Guangzhou, Guangdong Province, China Department of Medicine Doctors Medical Center Modesto CA USA Department of Toxicology, Zhengzhou University School of Public Health, Zhengzhou, China Department of Pathophysiology, Bengbu Medical College, Longzihu, Bengbu 233030, Anhui, P.R. China; Bengbu Medical College Key Laboratory of Cardiovascular and Cerebrovascular Diseases, Longzihu, Bengbu 233030, Anhui, P.R. China Center of Pulmonary Vascular Disease, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China School of Acupuncture and Moxibustion, Fujian University of CM, Fuzhou 350122, China. Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China. Department of Pediatric Nephrology, The Second Hospital of Lanzhou University, Lanzhou, Gansu, 730000, China Duke University Medical Center, Box 2926, Surgical Oncology Research Facility, Durham, North Carolina 27710 Department of Neurology, The Second Affiliated Hospital of GuangZhou Medical University, 250# Changgang East Road, GuangZhou, 510260, Guangdong Province, China; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and The Ministry of Education of China, Institute of Neuroscience and the Second Affiliated Hospital of GuangZhou Medical University, 250# Changgang east Road, GuangZhou, 510260, Guangdong Province, China Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710. Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Chaoyang District, Beijing 100101, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China Department of Gastroenterology Department of Physics Southern University of Science and Technology Shenzhen Guangdong 518055 China Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning, China Department of Hematology, Hainan Provincial People's Hospital, Haikou 570311, Hainan Province, China. College of Public Health Zhengzhou University Zhengzhou Henan China Center of Materials Science and Optoelectronics Engineering College of Materials Science and Optoelectronic Technology University of Chinese Academy of Sciences Beijing 100049 P. R. China Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co‐Innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products Nantong University Nantong Jiangsu China Guangxi Key Laboratory of Buffalo Genetics, Reproduction and Breeding, Guangxi Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Ministry of Agriculture and Rural Affairs, Nanning 530001, China State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu China College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China; School of Food Engineering, Rizhao Polytechnics, Rizhao, Shandong 276826, China Guangxi Veterinary Research Institute, Guangxi Key Laboratory of Veterinary Biotechnology, Nanning, People’s Republic of China Shanghai Skin Disease Hospital School of Medicine Tongji University Shanghai 200092 China Center of Clinical Laboratory, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China; Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Hangzhou, Zhejiang 310002, China Fujian Academy of Forestry, Shangchiqiao Road No. 35, Xindian, Fuzhou 350012, P. R. China College of Economics and Management, Shenyang Agricultural University, Dongling Road 120, Shenyang, Liaoning Province, China Department of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China; Tianjin Key Laboratory of Environment, Nutrition, and Public Health, Center for International Collaborative Research on Environment, Nutrition and Public Health, Tianjin 300070, China From the Department of Urology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China (L.H.); and Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Rd, Guangzhou 510630, China (Q.K., Z.L., J.W., Z.K., Y.Z.). Department of Cardiovascular Diseases, Merck Research Laboratories, Rahway, New Jersey Department of Biotechnology, Guangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning, China Institute of Physics and University of Chinese Academy of Sciences Chinese Academy of Sciences Beijing 100190 China Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, 110015, People's Republic of China Department of Gynaecology and Obstetrics, Hunan Provincial Maternal and Child Health Hospital, Changsha, Hunan, China [email protected]. Department of Breast Surgery, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University Taiyuan China Department of Infection, Enshi Tujia and Miao Autonomous Prefecture Center for Disease Control and Prevention, Hubei Province, China 1Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. The Center for Drug Research and Development Guangdong Pharmaceutical University Guangzhou Guangdong P.R. China Maize Research Institute Sichuan Agricultural University ChengDu 611130 China Statistics and Data Center Children's Oncology Group Monrovia California School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China, and Eco-materials and Renewable Energy Research Center, Nanjing University, Nanjing 210093, China Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine, Institute of Chinese Medicinal Sciences, Guangdong Pharmaceutical University, Guangzhou Higher Education Mega Center, Guangzhou, Guangdong 510006, P.R. China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. 1Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK; 2Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, China State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University Department of Ophthalmology, The Affiliated Hospital of Southwest Medical University, Luzhou, P.R. China School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, China Department of Pediatrics, The First Affiliated Hospital, Chengdu Medical College, Chengdu, Sichuan Province, P.R. China College of Animal Science and Technology Anhui Agricultural University Hefei P.R. China Department of Pediatric Nephrology, Rheumatology, and Immunology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College Huazhong University of Science and Technology Wuhan China General ICU/Department of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China Department of Rehabilitation Medicine, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China College of Life Science and Agronomy Zhoukou Normal University Zhoukou China Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China Institute of Physics, Chinese Academy of Sciences, Beijing 100190, People's Republic of China; Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China; Department of Nephropathy, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, PR China. Department of Biomedical Engineering, School of Basic Medical Sciences Guangzhou Medical University Guangzhou China Department of Oncology, First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi 341000, P.R. China Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China; Faculty of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Department of Pharmacy, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital, Shenzhen, China Department of Radiology The First Affiliated Hospital of Sun Yat‐Sen University Guangzhou P.R. China College of Public Health Zhengzhou University Zhengzhou China Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, P.R. China State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China; University of Chinese Academy of Sciences, Beijing, China Authors' Affiliations: Departments of 1Biochemistry and Molecular & Cellular Biology and 2Oncology, Georgetown University, Washington, District of Columbia Department of Respiratory Medicine Children's Hospital of Soochow University Suzhou China Department of Pathophysiology, Bengbu Medical College, Bengbu 233000, China From the Departments of Medicine and Cardiology, Mount Sinai School of Medicine, New York, NY (R.H., L.H., W.S.S., C.G., P.T., V.F., J.J.B.); Department of Cardiology, Elisabeth Klinikum, Schmalkalden, Germany (G.B.); Department of Medicine, Duke University, Durham, NC (M.E.K.); and Department of Medicine, Baylor College of Medicine, Houston, TX (P.E.K.). Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai 200433, China. [email protected] Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei 430000, P.R. China Department of Otolaryngology-Head and Neck Surgery, Xinhua Hospital Jiaotong University School of Medicine, Shanghai, 200092, China. Academy of Arts and Design, Tsinghua University , Beijing, 10084, China; The Future Laboratory, Tsinghua University , Beijing, 10084, China Key Laboratory of Gas Hydrate, Ministry of Natural Resources, Qingdao Institute of Marine Geology, Qingdao 266071, China; Laboratory for Marine Mineral Resources, Laoshan Laboratory, Qingdao 266071, China Pathology and Laboratory Medicine William G. Helis Memorial Laboratories Ochsner Medical Center New Orleans Louisiana School of Computing and Artificial Intelligence, Southwestern University of Finance and Economics, Chengdu, China Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control Technology, Hebei University of Technology, Tianjin 300130, People’s Republic of China; School of Electronic and Information Engineering, Hebei University of Technology, Tianjin, 300130, People’s Republic of China National Synchrotron Radiation Laboratory; University of Science and Technology of China; Hefei; P. R. China Department of Critical Care Medicine, Xiangya Hospital Central South University, Changsha, China Optogenetics & Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai 200237, China. Guangxi Key Laboratory of Veterinary Biotechnology; Guangxi Veterinary Research Institute; Nanning; China School of Materials Science and Engineering, Shanghai University, Shanghai 200072, China. Department of Immunology and Biochemistry, School of Basic Medical Sciences Tianjin Medical University Tianjin People's Republic of China; Tianjin Key Laboratory of Cellular and Molecular Immunology, Research Center of Basic Medical Sciences Tianjin Medical University Tianjin People's Republic of China; Key laboratory of Educational Ministry of China, Research Center of Basic Medical Sciences Tianjin Medical University Tianjin People's Republic of China; Laboratory of Molecular Immunology, Research Center of Basic Medical Sciences Tianjin Medical University Tianjin People's Republic of China Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, People’s Republic of China Guangxi Key Laboratory of Animal Vaccines and Diagnostics, Guangxi Veterinary Research Institute, Nanning, Guangxi Province, China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; College of Life Science, University of Chinese Academy of Sciences, Beijing, China Key Laboratory of Biotechnology and Crop Quality Improvement of the Ministry of Agriculture, Biotechnology Research Center Southwest University Chongqing 400716 China Department of Anesthesiology, Lu’an Hospital Affiliated to Anhui Medical University, Lu’an People’s Hospital, Lu’an School of Chemistry and Chemical Engineering; Qilu University of Technology (Shandong Academy of Sciences); Jinan 250353; PR China Research Center for Nutrition and Food Safety Institute of Military Preventive Medicine Third Military Medical University Chongqing Key Laboratory of Nutrition and Food Safety Chongqing Medical Nutrition Research Center Chongqing People's Republic of China State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases Sichuan University Chengdu China; Department of Orthodontics, West China School and Hospital of Stomatology Sichuan University Chengdu China Guangxi Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning, Guangxi, China Department of Toxicology, College of Public Health, Zhengzhou University, No. 100 Kexue Avenue, Zhengzhou, Henan 450001, China Chemistry and Life Sciences Group, Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, Royal Forest Herbarium, Bangkok 10900, Thailand, Department of Chemistry, Mahidol University, Bangkok 10400, Thailand, and Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612 Department of Mathematics, Zhejiang Sci-Tech University, Hangzhou, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-Sen University, Guangzhou, China State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine , Guangzhou, China College of Horticulture and Plant Protection; Yangzhou University; Yangzhou China Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; Supervision, Inspection and Testing Center for Fishery Environment and Aquatic Products (Harbin), Ministry of Agriculture and Rural Affairs, Harbin 150070, China Department of Clinical Laboratory, The First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, China Institute of Physics, Beijing Key Laboratory for Nanomaterials and Nanodevices, Chinese Academy of Sciences, Beijing 100190, P. R. China; Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China Institute of Plant and Food Science Department of Biology, School of Life Sciences Southern University of Science and Technology Shenzhen 518055 China; Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes School of Life Sciences Southern University of Science and Technology Shenzhen 518055 China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People's Republic of China Department of Plant Sciences and Plant Pathology , Montana State University, Bozeman, Montana 59717-3150 Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States Department of Pathophysiology, Bengbu Medical College, Bengbu 233030, China. Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of Agriculture Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences (CAAS) Wuhan China State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering Donghua University Shanghai China College of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu, China Guangxi Key Laboratory of Animal Vaccines and Diagnostics, Guangxi Veterinary Research Institute, Nanning, Guangxi, China Department of Pediatric Pulmonology, Children's Hospital of Soochow University Suzhou, China. Department of Pancreatobiliary Surgery and Center for Translational Medicine,the First Affiliated Hospital of Sun Yat‐sen University,Guangzhou,China Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of Agriculture Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences Wuhan China Tsinghua University The Future Laboratory, , Beijing, 100084 , China Department of Electrical and Computer Engineering; National University of Singapore; 117583 Singapore; Centre for Advanced 2D Materials and Graphene Research Centre; National University of Singapore Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, P. R. China School of Materials Science and Engineering; Fujian University of Technology; Fuzhou 350108; P. R. China Department of Rehabilitation Medicine, Qujing No. 1 Hospital , Yuanlin No. 1 Road, Qilin District , Qujing 655000 , Yunnan , China Pediatric Intensive Care Unit Guangzhou Women and Children's Medical Center Guangzhou China State Key Laboratory of Microbial Resources; Institute of Microbiology; Chinese Academy of Sciences; Beijing 100101; China Center for Emerging Infectious Diseases Wuhan Institute of Virology The Chinese Academy of Sciences Wuhan 430071 China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, P. R. China Department of Pediatrics Program in Developmental Biology and Neonatal Medicine, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine Indianapolis Indiana Research Institute of Exploration & Development, Daqing Petroleum Administrative Bureau, 163712, Daqing, China Department of Gastrointestinal Surgery, Wuhan Integrated TCM and Western Medicine Hospital (Wuhan No. 1 Hospital), Wuhan, Hubei 430022, P.R. China Department of Rehabilitation Medicine of The Third Affiliated Hospital of Sun Yat-sen Univerity, China Department of Urology and Andrology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China Zhejiang Key Laboratory of Traditional Chinese Medicine, Pharmaceutical Technology, Hangzhou, Zhejiang 310052, China Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT 59717, USA. State Key Laboratory of Ophthalmology, Retina Division, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China Intensive Care Unit, Xiangya Hospital, Central South University, Changsha 410008, China. School of Pharmacy, Ningxia Medical University, Yinchuan, China State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology Sichuan University Chengdu China; Department of stomatology Hospital of Chengdu University of Traditional Chinese Medicine Chengdu China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China. [email protected] Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University , Chengdu 610041, Sichuan , China National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China College of Horticulture and Plant Protection Yangzhou University Yangzhou China Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China Institute of Environmental Science, Fudan University, Shanghai 200433, China. Department of Orthopaedic Surgery, Haimen People’s Hospital Affiliated to Nantong University, Nantong, Jiangsu, China; Department of Orthopaedic Surgery, Haimen People’s Hospital Affiliated to Nantong University, Nantong, Jiangsu, China Department of Respiratory Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510120, P.R. China Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science College of Chemistry and Chemical Engineering Central South University Changsha 410083 P. R. China Taizhou People’s Hospital Affiliated to Nanjing Medical University, Taizhou, China State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources School of Life Sciences Sun Yat‐sen University Guangzhou 510275 China Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, China Department of Gerontology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine , Shanghai , China Central Hospital of Zibo, Zhangdian District, Zibo, Shandong, China. Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, People’s Republic of China Division of Fundamental Immunology, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, Heilongjiang, China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China State Key Laboratory of Biocontrol; Guangdong Provincial Key Laboratory of Plant Resources; Collaborative Innovation Center of Genetics and Development; School of Life Sciences; Sun Yat-sen University; Guangzhou, China Department of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan, China Department of Pathophysiology, Bengbu Medical College, Anhui 233000, China Department of Gastroenterology The First Affiliated Hospital of Nanchang University Jiangxi Province China Translational Medicine Institute, National & Local Joint Engineering Laboratory for High-throughput Molecular Diagnosis Technology, Affiliated to The First People's Hospital of Chenzhou, University of South China, Chenzhou 423000, P.R. China; Center for Clinical Pathology, Affiliated to The First People's Hospital of Chenzhou 423000, P.R. China Shanghai East Hospital, The Institute for Biomedical Engineering & Nano Science (iNANO), School of Medicine Tongji University Shanghai 200092 China State Key Laboratory of Microbial Resources Institute of Microbiology, Chinese Academy of Sciences Beijing 100101 China; College of Life Sciences University of Chinese Academy of Sciences Beijing 100049 China First and eighth authors: Montana State University, Department of Plant Sciences and Plant Pathology, Bozeman 59717-3150; second author: Cereal Disease Laboratory, United State Department of Agriculture–Agricultural Research Service (USDA-ARS), St. Paul, MN 55108; third and fourth authors: Wheat Genetics, Physiology, Quality, and Disease Research Unit, USDA-ARS, Pullman, WA 99164-6430; fifth author: International Maize and Wheat Improvement Center (CIMMYT), ICRAF House, United Nations Avenue, Gigiri, P.O... Department of Pancreatobiliary Surgery The First Affiliated Hospital of Sun Yat‐sen University Guangzhou China Department of Immunology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan, People's Republic of China. College of Clinical Medicine, Chengdu University of Traditional Chinese Medicine Surgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States Department of Microbiology, University of Guelph, Guelph, Ontario NIG 2W1, Canada Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, P. R. China Institute of Light Industry and Food Engineering, Guangxi University, Nanning 530005, China Jinhua People's Hospital Jinhua Zhejiang PR China Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan, China Department of Plant Sciences and Plant Pathology, Montana State University, 307 Plant BioScience Bldg, P.O. Box 173150, Bozeman, MT, 59717, USA. [email protected]. Department of Pathophysiology Xiangya School of Medicine, Central South University Hunan China; Sepsis Translational Medicine Key Lab of Hunan Province, Central South University Hunan China Department of Gynecology, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang, PR, China Department of Biochemistry, School of Hygiene and Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205 Surgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina27710, United States Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control Technology, School of Materials Science and Technology, Hebei University of Technology, Tianjin 300130, People's Republic of China Microbial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen (IMIT), University of Tübingen, Germany; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Wenjiang, People's Republic of China State Key Laboratory of Tribology, Tsinghua University, Beijing 100084, China Department of Respiratory and Critical Care Medicine, The First People's Hospital of Longquanyi District, Chengdu, China Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, People’s Republic of China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, People’s Republic of China Academy of Arts and Design, Tsinghua University , 10084, Beijing, China; The Future Laboratory, Tsinghua University , 10084, Beijing, China Medical Research Center for Structural Biology School of Basic Medical Sciences Wuhan University Wuhan 430071 China Department of Physics, Southern University of Science and Technology, Shenzhen 518055, China College of Light Industry and Food Engineering Guangxi Univ. Nanning 530004 China Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University Department of Physics Southern University of Science and Technology (SUSTech) No. 1088, Xueyuan Rd Shenzhen 518055 Guangdong P. R. China Department of Obstetrics and Gynecology, Chongqing Maternal and Child Health Hospital (Shapingba District) National Clinical Research Center for Geriatrics, West China Hospital Sichuan University Chengdu China School for Radiological and Interdisciplinary Sciences (RAD–X) & College of Chemistry; Chemical Engineering and Materials Science; Soochow University; Suzhou 215123; China Department of Nephrology, Xinqiao Hospital, The Third Military Medical University, Chong Qing, China Department of Ophthalmology, the Affiliated Hospital of Southwest Medical University, Luzhou, P.R. China Hubei Key Laboratory of Theory and Application of Advanced Material Mechanics, School of Science, Wuhan University of Technology, Wuhan 430070, China From the Departments of Ophthalmology and Visual Science, Guangzhou Medical University Guangzhou Guangdong China College of Mechanical and Electrical Engineering, Sichuan Agriculture University, Ya’an 625014, China College of Physical Education, Southwest University, China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China Department of Pathophysiology,Bengbu Medical College,Bengbu 233030,China. Novogen Limited, North Ryde, New South Wales, Australia Department of Physics; Southern University of Science and Technology; Shenzhen 518005; P. R. China Guangxi Key Laboratory of Veterinary Biotechnology Guangxi Veterinary Research Institute Nanning Guangxi China Department of Intensive Care Unit, Xiangya Hospital, Central South University, Changsha, China RESCUE BT Trial Investigators Academy of Arts and Design Tsinghua University Beijing China; The Future Laboratory Tsinghua University Beijing China School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of Electrochemical Energy Materials, Guangxi University, Nanning, 530004, China Department of Ophthalmology Louisville, Kentucky, USA; School of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China Program of Immunology, Department of Internal Medicine and Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Zhongshan School of Medicine, Sun Yat-sen University, China From the Departments of Cardiovascular Diseases (L.H., A.Z., S.D.W., M.S.S., J.E., J.C.), Drug Discovery Sciences (F.W., F.U.), and Infectious Diseases and Immunology (J.M.A., M.S.), Merck Research Laboratories, Rahway, NJ. School of Medicine, Guangxi University of Science and Technology, Liushi Road 257, Liuzhou 545025, China Department of Joint and Orthopedics Zhujiang Hospital Southern Medical University Guangzhou Guangdong China The Future Laboratory, Tsinghua University , Beijing, 100084 , China Department of Ophthalmology, Fujian Medical University Union Hospital, Fuzhou, China; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States College of Medicine, Pingdingshan University, Pingdingshan City, Henan Province, China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China Guangdong Provincial Key Laboratory of Lingnan Specialty Food Science and Technology Zhongkai University of Agriculture and Engineering Guangzhou China Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Department of Respiratory Medicine, Xiangya Hospital of Central South University, Changsha, Hunan, P.R. China for the GDLM group State Key Laboratory of Large Yellow Croaker Breeding Ningde Fujian China; Key Laboratory of Healthy Mariculture for the East China Sea, Ministry of Agriculture Fisheries College, Jimei University Xiamen Fujian China Department of Surgery; Duke University Medical Center; Durham; USA College of Light Industry and Food Engineering, Guangxi University, Nanning, PR China McLaughlin Research Institute, 1520 23rd Street South, Great Falls, MT 59405,USA School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, PR China Authors' Affiliations: 1College of Life Sciences, Nankai University, Tianjin; 2The State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences; and 3Key Laboratory of Carcinogenesis and Translational Research, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing, China Guangxi Engineering Center for Biomaterials for Tissue and Organ Regeneration, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China Department of General Surgery, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai , China College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China Shanxi University of Chinese Medicine, Taiyuan, Shanxi, China Wheat Genetics Resource Center, Department of Plant Pathology, Kansas State University, Manhattan, Kansas 66506-5502 United States Department of Agriculture, Agricultural Research Service, Crop Production and Pest Control Research Unit, West Lafayette, Indiana 47907 (S.R.S., A.S.B.); Department of Agronomy, Purdue University, West Lafayette, Indiana 47907 (S.R.S., A.S.B.); and Department of Plant Pathology, Throckmorton Plant Sciences Center, Kansas State University, Manhattan, Kansas 66506 (L.H., B.S.G.) Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan China; Ministry of Education Key Laboratory of Environment and Health School of Public Health, Tongji Medical College, Huazhong University of Science and Technology Wuhan China School of Materials Science and Technology; Research Institute for Energy Equipment Materials; Tianjin Key Laboratory of Materials Laminating Fabrication and Interface Control Technology; Hebei University of Technology; Tianjin Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, People's Republic of China; Avian Disease Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Chengdu, Sichuan, People's Republic of China; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan, People's Republic of China Department of Biotechnology, Guangxi Key Laboratory of Animal Vaccines and Diagnostics, Guangxi Veterinary Research Institute, Nanning, Guangxi, PR China Division of Endocrinology and Metabolism West China Hospital of Sichuan University Chengdu Sichuan China College of Biology and the Environment, Nanjing Forestry University, Longpan Road 159, Xuanwu District, Nanjing 210037, China Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. Department of Laboratory Medicine, First Affiliated Hospital of Guangxi Medical University, Nanning, China State Key Laboratory for Conservation and Utilization of Subtropical Agro‐bioresources College of Life Science and Technology Guangxi University Nanning China Department of Plant Sciences and Plant Pathology Montana State University Bozeman MT 59717‐3150 USA People’s Hospital of Xuyong County, Luzhou, Sichuan Province, China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, MOE Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China Children's Hospital Affiliated Soochow University, Suzhou 215003, China. [email protected] Food Quality and Safety Research Institute, South China Agriculture University, Guangzhou, Guangdong Province, 510642, P. R. China, Department of Medical Research, Guangzhou Liuhuaqiao Hospital, Guangzhou, Guangdong Province, 510010, P. R. China, and Guangdong Agriculture, Industry and Business Polytechnic College, Guangzhou, Guangdong Province, 510507, P. R. China State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa, Macao 999078, People’s Republic of China The National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, P.R. China Gannan Innovation and Translational Medicine Research Institute,Department of Oncology,First Affiliated Hospital, Gannan Medical University,Ganzhou,China; Jiangxi Clinical Medical Research Center for Cancer,Ganzhou,China Fred Hutchinson Cancer Research Center 2 , Seattle, Washington 98109 Taihe Hospital Affiliated to Hubei Medical College, Shiyan, China Department of Immunology, Baylor College of Medicine, Houston, TX Department of Urology and Lin Bai-xin Research Center (QP, XF), Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China Department of Physics Southern University of Science and Technology Shenzhen Guangdong 518055 P. R. China Department of Immunology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Immunology, MD Anderson Cancer Center, University of Texas, Houston, TX 77030, USA. State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Keyuan Road 4, Gaopeng Street, Chengdu 610041, China Pediatric Intensive Care Unit, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China Department of Physics, Southern University of Science and Technology, Shenzhen 518055, China. Institute for Diabetes, Obesity, and Metabolism (L.H., P.S.), Department Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania Philadelphia, Pennsylvania 19104 School of Physical Education, Southwest University, Chongqing 400715, China China-Japan Friendship Hospital, Beijing 100029. Department of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, China. State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat‐sen University Guangzhou China Surgical Science, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710 College of Animal Science and Technology, Zhejiang A&F University, Lin'an 311300, Zhejiang, China. Department of Hematology, Hainan General Hospital, Haikou, Hainan, 570311, P.R. China Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430030 , PR China; Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei 430030 , PR China Department of Surgery, Duke University Medical Center, Durham, North Carolina. Emergency Department, Xiangya Hospital, Central South University, Changsha, Hunan, China College of Biological and Environmental Engineering Binzhou University Binzhou China College of Materials Science and Engineering; Huaqiao University; Xiamen 361021; China; Key Laboratory of Molecular Designing and Green Conversions (Huaqiao University) Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China School of Life Sciences, and Hubei Key Laboratory of Genetic Regulation and Integrative Biology Central China Normal University Wuhan Hubei China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China. College of Light Industry and Food Engineering, Guangxi University, Nanning, Guangxi 530004, China Institute of Physics and University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190, P. R. China; Songshan Lake Materials Laboratory, Dongguan, Guangdong 523808, P. R. China Laboratory of Cell & Molecular Biology Institute of Vegetable Science Zhejiang University Hangzhou 310058 China; Key Laboratory of Horticultural Plant Growth, Development and Quality Improvement Ministry of Agriculture/Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology Hangzhou 310058 China Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China China-Japan Freindship Hospital, China Department of Hepatobiliary Surgery and Center for Translational Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangdong, China College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China Department of Electrical and Computer Engineering; National University of Singapore; Singapore; Centre for Advanced 2D Materials; National University of Singapore Department of Physics, South University of Science and Technology of China, Shenzhen 518055, China; Shenzhen Key Laboratory of Thermoelectric Materials, Shenzhen 518055, China Department of Microbiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada Natural Products Research Laboratories, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, and Panacos Pharmaceuticals, 209 Perry Parkway, Gaithersburg, Maryland 20877 Department of Ophthalmology, The Affiliated Hospital of Southwest Medical University, Luzhou, China *State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150001, China; and The Key Laboratory of Biology and Genetic Improvement of Oil Crops, The Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan 430000, China Natural Products Research Laboratories, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, Medical Center, Box 2926, SORF, Duke University, Durham, North Carolina 27710, Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, and Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata 950-2081, Japan Science and Technology on Surface Physics and Chemistry Laboratory 1 , Mianyang 621908, China Department of Pathophysiology, Bengbu Medical College, Bengbu 233030, China. E-mail: [email protected]. State Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China; College of Life Sciences University of the Chinese Academy of Sciences Beijing 100049 China *Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China; †Heilongjiang Provincial Key Laboratory of Veterinary Immunology, Harbin, China Division of Fundamental Immunology, National African Swine Fever Para-reference Laboratory, State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang, China; Heilongjiang Provincial Key Laboratory of Veterinary Immunology , Harbin, Heilongjiang, China Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University , Chengdu, Sichuan Province , China State Key Laboratory of Microbial Resources Institute of Microbiology, Chinese Academy of Sciences Beijing China State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, PR China Reproductive Medical and Genetic Centre, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China Department of Rheumatology and Immunology The First Affiliated Hospital of Yangtze University Jingzhou China Chemistry and Life Sciences Group, Research Triangle Institute, P.O. Box 12194, Research Triangle Park, North Carolina 27709, LTF-Universidade Federal da Paraiba, Caixa Postal 5009, 58059 Joao Pessoa, PB, Brazil, and Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612 Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, China Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Xinzao Town, Panyu District, Guangzhou, Guangdong, China INSEAD, Fontainebleau, France Department of Physics; South University of Science and Technology of China; Shenzhen 518005; P.R. China School of Biological and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, China Nephrology Department of the First Affiliated Hospital of Army Medical University, Chongqing, China Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine and Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China and Institute of Chinese Medicine, Guangdong Pharmaceutical University and Guangdong TCM Key Laboratory for Metabolic Diseases, Guangzhou, Guangdong 510006, P.R. China Department of Vascular Surgery; The Second Affliated Hospital of Nanchang University; China School of Chemistry and Chemical Engineering Institution of Molecular Engineering and Applied Chemistry Anhui University of Technology Maanshan 243002 People's Republic of China Guangdong Provincial Key Laboratory of Energy Materials for Electric Power, Southern University of Science and Technology, Shenzhen 518055, P. R. China National Clinical Research Center of kidney Diseases, JinLing Hospital, Nanjing University School of medicine, Nanjing, China From the Centre for Health Policy (X.X., L.H., K.D.), Melbourne School of Population and Global Health, The University of Melbourne, Victoria; Emergency Department (D.H.), Queensland Children's Hospital; University of Queensland (D.W.H.); Mater Research Institute (D.H.), Brisbane, Queensland; Emergency Department (M.L.B.), Perth Children's Hospital; Divisions of Emergency Medicine and Paediatrics (M.B.), University of Western Australia, Perth; Department of Emergency Medicine (A.D., S.H., M.T.M., J... Department of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China Department of Allergy, Immunology, and Pulmonary Medicine, and Department of Pathology, Children's Research Institute, Children's National Medical Center; and Department of Pediatrics and Department of Biochemistry and Molecular Biology, George Washington University, Washington, District of Columbia The Centre for Drug Research and Development Guangdong Pharmaceutical University Guangzhou Guangdong P. R. China National Integrated Traditional and Western Medicine Center for Cardiovascular Disease, China-Japan Friendship Hospital, Beijing 100029, China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101 China; College of Life Science, University of Chinese Academy of Sciences, Beijing, 100049 China Department of Chemistry, University of Wisconsin, Madison, Wisconsin, Institute for Systems Biology, Seattle, Washington, and UW Medicine at South Lake Union, 815 Mercer Street, Seattle, Washington 98109 McLaughlin Research Institute for Biomedical Sciences, 1520 23rd Street South, Great Falls, MT 59405, USA Department of Orthopaedics Hospital 411 of CPLA Shanghai China Henan Engineering Research Center of Resource & Energy Recovery from Waste; Henan University; Kaifeng 475004; PR China Department of Cardiology Pulmonary Vascular Disease Center State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing People's Republic of China Sichuan Academy of Traditional Chinese Medicine Science, Chengdu Sichuan China Health Economics Unit, Centre for Health Policy, Melbourne School of Population and Global Health Melbourne Victoria Australia Institute of Physics & University of Chinese Academy of Sciences Chinese Academy of Sciences Beijing 100190 China; Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China The MOE Key Laboratory of Cell Proliferation and Differentiation School of Life Sciences Peking University Beijing China Department of Endocrinology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland) Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China School of Materials Science and Engineering, Shanghai Key Laboratory of D&A for Metal-Functional Materials, Tongji UniversityShanghai 201804, PR China. Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China. Surgical Oncology Research Facility, Duke University Medical Center, Box 2926, Durham, North Carolina 27710, United States Department of Translational Neuroscience Jing’ an District Centre Hospital of Shanghai State Key Laboratory of Medical Neurobiology & Institutes of Brain Science Fudan University China Department of Urology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, People’s Republic of China Department of Electrical and Computer Engineering National University of Singapore 4 Engineering Drive 3 117583 Singapore Department of Critical Care Medicine, Xiangya Hospital, Central South University, Changsha 410008. [email protected]. College of Chemistry and Chemical Engineering, Guangxi Key Laboratory of Electrochemical Energy Materials, Guangxi University, Nanning 530004, China Contribution from the Department of Chemistry and Center in Molecular Toxicology, Vanderbilt University, Nashville, Tennessee 37235, and Eppley Institute for Research in Cancer and Allied Diseases and Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6805 Department of Pathology Ochsner Clinic Foundation New Orleans LA USA Ochsner Health System, New Orleans, LA Division of NephrologyDivision of Infectious DiseasesMount Sinai School of MedicineNew YorkNew YorkUSA State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China; Department of Biology, Pomona College, Claremont, California 91711,1 and; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People’s Republic of China2 Beijing National Laboratory for Condensed Matter Physics Institute of Physics University of Chinese Academy of Sciences Chinese Academy of Sciences Beijing 100190 China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, PR China State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, Heilongjiang 150069, China China-Japan Friendship Hospital Beijing 100029, China. The Future Laboratory, Tsinghua University , Beijing 100084, China College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, Henan, China Department of Cancer Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030 Department of Laboratory Medicine, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Hangzhou, China Department of Breast Surgery, Shanxi Provincial Cancer Hospital, Shanxi Medical University, Taiyuan, Shanxi, China Department of Physics Southern University of Science and Technology Shenzhen 5158055 P. R. China State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine , Guangzhou , China State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, People's Republic of China Department of Pediatrics Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA. Department of Neonatology, Children's Medical Center, Hunan Provincial People's Hospital The First Affiliated Hospital of Hunan Normal University Changsha Hunan China Department of Physics, Southern University of Science and Technology, Shenzhen 518005, P. R. China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China |
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