http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_a9cfbdcd7b2ccaf10cee98d852b60595
Outgoing Links
Predicate | Object |
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family-name | Jun Ma Ma |
name | Jun Ma Jun. Ma |
given-name | Jun Jun. |
organization-name | Molecular Medicine Research Laboratories, Robarts Research Institute, London, Canada.; Don Rix Protein Identification Facility, Department of Biochemistry and Western University, London, Canada. Department of Neurobiology College of Basic Medicine China Medical University Shenyang China; Institute of Pathology and Pathophysiology China Medical University Shenyang China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China, National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, Harbin 150090, China, and Environmental Science and Engineering Research Center, Harbin Institute of Technology, Shenzhen Graduate School, Shenzhen 518055, China State Key Laboratory of Urban Water Resources and Environment, National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, Harbin 150090, China. Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang 110122, People's Republic of China Department of Neurobiology College of Basic Medicine China Medical University Shenyang People's Republic of China; Institute of Pathology and Pathophysiology China Medical University Shenyang People's Republic of China Indiana University—Purdue University, Fort Wayne 2 Molecular Medicine Research Laboratories, Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada; 3 Department of Biochemistry, Don Rix Protein Identification Facility, Western University, London, Ontario, Canada Division of Biomedical Informatics, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Division of Developmental Biology, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA Department of Otolaryngology-Head and Neck Surgery, Yijisan Hospital of Wanan Medical College, Wuhu, Anhui 241001, China Qingdao Industrial Energy Storage Research Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao 266101 P. R. China Department of Pathology The First Affiliated Hospital of Wenzhou Medical University Wenzhou China Key Laboratory of Green Chemistry and Technology (Ministry of Education), College of Chemistry, Sichuan University, Chengdu 610064, China College of Chemistry and Chemical Engineering, Southwest University, Chongqing, China UniSA STEM and Future Industries Institute, University of South Australia, Mawson Lakes, SA 5095, Australia Department of Cardiology, The Affiliated Hospital of Southwest Medical University, Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, China Department of Thoracic Surgery, Heji Hospital, Changzhi Medical College, Changzhi, Shanxi 046011, P.R. China Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China Department of Biochemistry Case Western Reserve University School of Medicine Cleveland OH USA Department of Integrative Medicine, Zhongshan Hospital, Fudan University Shanghai 200032, China. Palo Alto Medical Foundation Research Institute, Palo Alto, USA ; Department of Medicine, Stanford University School of Medicine, Stanford, USA. National Institute for Materials Science, Tsukuba 305-0042, Japan Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Colloid and Interface and Thermodynamics CAS Research/Education Center for Excellence in Molecular Sciences Center for Carbon Neutral Chemistry Institute of Chemistry Chinese Academy of Sciences Zhongguancun North First Street 2 Beijing 100190 P. R. China Authors' Affiliations: 1State Key Laboratory of Oncology in Southern China, Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China; Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, PR China.; Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou, Zhejiang, PR China. Hainan Key Laboratory for Conservation and Utilization of Tropical Marine Fishery Resources, Sanya, Hainan, China;; College of Life Science and Ecology, Hainan Tropical Ocean University, Sanya, China; School of Life Sciences University of Science and Technology of China Hefei 230027 China Research Center, Eye and ENT Hospital of Fudan University, Shanghai, China School of Information Science and Engineering, Lanzhou University , Lanzhou 730000, China School of Municipal and Environmental, Harbin Institute of Technology, Harbin 150090, China. [email protected] Collider-Accelerator Department, Brookhaven National Laboratory 1 , Upton, New York 11973, USA Center for Anesthesiology; Beijing Anzhen Hospital, Capital Medical University; Beijing China Department of Neurosurgery, University of Minnesota , Minneapolis, Minnesota , USA State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, P.R. China; National Engineering Research Center of Urban Water Resources, Harbin 150090, P.R. China College of Pharmaceutical Engineering of Traditional Chinese Medicine, State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, P. R. China; Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, P. R. China Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, P. R. China; Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, P. R. China Department of Medical Microbiology, Immunology, & Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine, 913 N. Rutledge Street, Springfield, IL 62794, U.S.A. Institute of Image Processing & Pattern Recognition, Shanghai Jiaotong University, Shanghai 200240, China. [email protected] Department of Engineering; University of South Australia; Mawson Lakes SA5095 Australia Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China Zhongshan Hospital, Fudan University, Xuhui District, Shanghai 200032, P. R. China Advanced Biomaterials and Tissue Engineering Center Huazhong University of Science and Technology Wuhan China; Department of Biomedical Engineering, College of Life Science and Technology Huazhong University of Science and Technology Wuhan China School of Advanced Manufacturing and Mechanical Engineering, University of South Australia, Adelaide, South Australia 5095, Australia Department of Medicine Stanford University School of Medicine California USA; Department of Health Services Research Palo Alto Medical Foundation Research Institute California USA Center for Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China. Email: [email protected]. Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA School of Engineering, University of South Australia, Mawson Lakes, SA 5095, Australia Department of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation Center, The Calmette Affiliated Hospital of Kunming Medical University, The First People’s Hospital of Kunming, Clinical Medical Center for Organ Transplantation of Yunnan Province, Kunming, China. Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China Department of Medicine and Institute of Health Research and Policy, University of Illinois, Chicago Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China Department of Developmental Biology, Children's Hospital Research Foundation,3333 Burnet Avenue, Cincinnati, OH 45229, USA Department of Physics, Northwest University, Xian 710069, China Shanghai Center for Plant Stress Biology Chinese Academy of Sciences Shanghai 201602 China National Institute of Mental Health Hefei National Laboratory for Physical Sciences at the Microscale Frontiers Science Center for Planetary Exploration and Emerging Technologies School of Chemistry and Materials Science National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei Anhui 230026 China School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Electrochemical Energy Device Research Center (SEED) and In-situ Center for Physical Sciences, Shanghai Jiao Tong University, Shanghai 200240, People’s Republic of China Department of Neurosurgery, University of Minnesota, Minneapolis, Minnesota, USA; Department of Neurosurgery, Beijing Tiantan Hospital affiliated to Capital Medical University, Beijing, China Harbin Institute of Hematology and Oncology Harbin 150010 Heilongjiang P. R. China Tianjin Medical University China. Department of Radiology, Beijing Tiantan Hospital Capital Medical University Beijing China College of Veterinary Medicine, Northeast Agricultural University, Harbin, People’s Republic of China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine, Northeast Agricultural University, Harbin, People’s Republic of China Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese Medical University, 899 Guangqiong Road, Jiaxing 314001, P. R. China; Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, Department of Orthopaedics, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, People’s Republic of China Hohai University Nanjing 210098 P. R. China Institute of Child and Adolescent Health, Peking University, Beijing 100191, China. SMART Infrastructure Facility, University of Wollongong, Wollongong, NSW, Australia. Department of Cardiothoracic Surgery Longyan First Hospital Longyan City China Department of Anesthesiology, Anhui Provincial Hospital Affiliated Anhui Medical University, Hefei, Anhui 230001, P.R. China Department of Plant Protection, Hunan Agricultural University, Changsha 410128, China. [email protected] Department of Drug Discovery and Development, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan Harbin Institute of Haematology and Oncology Harbin China Department of Orthopedics, and Nanjing University of Science & Technology Department of Health Policy and Administration Institute for Health Research and Policy, University of Illinois at Chicago Chicago Illinois USA Department of Oncology, Huai'an TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Huai'an, Jiangsu 223001, P.R. China Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA Tianjin Medical University, Heping, Tianjin, People’s Republic of China Heilongjiang Academy of Agricultural Sciences, Harbin, Heilongjiang, China Department of Mathematics and Statistics , Macquarie University , Sydney , Australia Department of Chemistry, University of WisconsinMilwaukee, 3210 North Cramer Street, Milwaukee, Wisconsin 53211 State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; College of Life Sciences, Graduate School of CAS, Beijing 100049, China Department of Foreign Affairs for Scientific Research, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China Department of Physics, Lanzhou University of Technology 2 , Lanzhou 730050, China Department of Neurosurgery, Second Affiliated Hospital of Nanjing Medical University Sun Yat-Sen University Cancer Center, State Key laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, People's Republic of China Radiotherapy Department, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210000, P. R. China Department of Hematology and Oncology, Harbin Institute of Hematology and Oncology, Harbin, China College of Life Sciences and Engineering, Foshan University, Foshan, People’s Republic of China Palo Alto Medical Foundation Research InstitutePalo Alto, CaliforniaandStanford University School of MedicineStanford, California College of Chemistry and Material Science, Sichuan Normal University, Chengdu, People’s Republic of China 1D Nanomaterials Research Group, National Institute for Materials Science, Tsukuba, Ibaraki 305-0047, Japan Department of Neurobiology, China Medical University, Shenyang 110122, China; Department of Physiology, College of Basic Medicine, China Medical University, Shenyang 110122, China Nurix Therapeutics, Inc., 1700 Owens St., San Francisco, California 94158, United States Department of Interventional Radiology Tongren Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Colloid and Interface and Thermodynamics, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China Department of Translational Medicine, Wadsworth Laboratories, New York State Department of Health Albany New York Department of Orthopaedics, Changzheng Hospital Navy Medical University Shanghai China Laboratoire de Chimie Physique; CNRS/Université Paris-Sud 11; 91405 Orsay; France Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang 110122, People's Republic of China; Institute of Pathology and Pathophysiology, China Medical University, Shenyang 110122, People's Republic of China Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ont., Canada M5G 1L5. Department of Orthopedics Second Affiliated Hospital Naval Medical University Shanghai 200003 P. R. China; Translational Research Center of Orthopedics Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 P. R. China Department of Endocrinology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China , Changsha , Hunan, 410004 , China School of Chemistry and Materials Science Center for Micro and Nanoscale Research and Fabrication Hefei National Research Center for Physical Sciences at the Microscale Instruments Center for Physical Science National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei Anhui 230026 P. R. China Department of Epidemiology and Biostatistics, School of Public Health Tianjin Medical University Tianjin China Laboratoire de Chimie Physique/ELYSE, UMR 8000, CNRS/Univ. Paris-Sud, Bât. 349, 91405 Orsay, Cedex, France Department of Health Policy and Administration, Institute for Health Research and Policy, University of Illinois at Chicago, Chicago Radiotherapy Department Affiliated Hospital of Nanjing University of Chinese Medicine China Department of Bone Marrow Transplantation, Harbin Hematological Cancer Institute, Harbin the First Hospital, Harbin Province, P.R. China State Key Laboratory of Geomechanics and Geotechnical Engineering, Chinese Academy of Sciences, Wuhan, China; University of Chinese Academy of Sciences, Beijing, China; Hubei Province Key Laboratory of Contaminated Sludge and Soil Science and Engineering, Wuhan, China Department of Mathematics Nanjing University of Science and Technology Nanjing 210094 P. R. China College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, P. R. China; Heilongjiang Provincial Key Laboratory of Pathogenic Mechanism for Animal Disease and Comparative Medicine, Harbin, 150030, P.R. China Shenzhen Geim Graphene Center Tsinghua‐Berkeley Shenzhen Institute & Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen 518055 China Shaanxi University of Science and Technology, Xi’an, Shaanxi, China Department of Urology, Kunshan Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China Institute of Child and Adolescent Health, School of Public Health, Peking University National Health Commission Key Laboratory of Reproductive Health Beijing China Department of General Surgery, Zhejiang Provincial Peoples’ Hospital, Peoples’ Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China (mainland) Department of Oncology, The Affiliated Huai’an Hospital of Xuzhou Medical University and The Second People’s Hospital of Huai’an, No.60, Huaihai Road (S.), Huai’an, 223002, Jiangsu, China Qingdao Industrial Energy Storage Technology Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao 266101 China Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Canton, Guangdong, China Department of Chemistry, and Shanghai Key Lab of Chemical Assessment and Sustainability; Tongji University; Shanghai; China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, Heilongjiang 150090, China Department of Cardiology Ren Ji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China School of Public Health, Institute of Child and Adolescent Health, Peking University, No. 38 Xueyuan Road, Haidian District, Beijing 100191, China College of Science, National University of Defense Technology, Changsha, People’s Republic of China, 410073 Palo Alto Medical Foundation Research Institute, Palo Alto, California. Department of Surgery Oncology, The Anqing Municipal Hospital Anqing 246003, Anhui Province, China. State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, 150090, China From the Program on Prevention Outcomes and Practices (R.S.S., V.M., J.M.), Stanford Prevention Research Center, Stanford University, Palo Alto, Calif; and the Department of Public Health Sciences (C.D.F.), Wake Forest University School of Medicine, Winston-Salem, NC. Transplantation Center, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. School of Public Health/Institute of Child and Adolescent Health, Peking University, Beijing 100191, China. School of Municipal & Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China. Department of Radiation Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou China College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China Department of Biology, University of Pennsylvania, Philadelphia, PA 19104 Palo Alto Medical Foundation Research Institute, Palo Alto, CA; Stanford University, Palo Alto, CA; Department of Medicine and Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL National Synchrotron Radiation Laboratory, School of Nuclear Science and Technology, Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China; Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou, Jiangsu 215123, P. R. China Department of Neurosurgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China Department of Radiology, Beijing ChuiYangLiu Hospital, Beijing, China. Department of Interventional Radiology Tongren Hospital Shanghai Jiaotong University School of Medicine China Qingdao Industrial Energy Storage Technology Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao 266101 P. R. China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, Guangdong, People's Republic of China State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Division of Biomedical Informatics, Cincinnati Children's Research Foundation, Cincinnati, OH 45229; Division of Developmental Biology, Cincinnati Children's Research Foundation, Cincinnati, OH 45229; Department of Chemistry and Biology, National University of Defense Technology, Changsha 410072, China Department of Thoracic Surgery Shanxi Province People's Hospital Taiyuan P.R. China Institute of Xinjiang Yili Animal Science Yining, Xinjiang China 1Department of Medical Microbiology, Immunology and Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine, Springfield, Illinois. Department of Research and Development, Shenzhen Wanhe Pharmaceutical Co., Ltd., Shenzhen, Guangdong 518107, P.R. China Beijing National Laboratory for Molecular Sciences; Key Laboratory of Colloid and Interface and Thermodynamics; Institute of Chemistry; Chinese Academy of Sciences; Beijing 100190 Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China Department of Neurobiology School of Life Sciences China Medical University Shenyang China; Key Laboratory of Cell Biology Ministry of Public Health of China China Medical University Shenyang China; Key Laboratory of Medical Cell Biology Ministry of Education of China China Medical University Shenyang China College of Landscape Architecture-Sichuan Agricultural University, Chengdu- Sichuan, China School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, P. R. China Key Laboratory of Jiangxi Province for Environment and Energy Catalysis, College of Chemistry, Nanchang University, Nanchang, Jiangxi 330031, China Department of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Nanfang Hospital, Southern Medical University, Department of Burns, Guangzhou, China Department of Chemistry and Department of Radiology, Washington University, Saint Louis, Missouri 63130-4899, and Department of Chemical and Biological Engineering, State University of New York at Buffalo, Buffalo, New York 14260 Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center of Cancer Medicine, Peoples Republic of China Institute of Forensic Science of Changzhou, Changzhou, Jiangsu 213003, China. Bicycle Therapeutics, 4 Hartwell Place, Lexington, Massachusetts 02421, United States Institute of Digestive Diseases, The Second Affiliated Hospital of Zhengzhou University, No. 2, Jingba Road, Zhengzhou 450014, PR China Department of Orthopaedics, People's Hospital of Suqian, Drum Tower Hospital Group of Nanjing, Suqian Jiangsu 223800, PR China. Department of Engineering, University of Cambridge, Cambridge, UK Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China; School of Materials Science and Engineering, University of Science and Technology of China, Shenyang 110016, China Department of Veterinary Surgery, Northeast Agricultural University, Harbin, China College of Information Science and Engineering, Ocean University of China, Qingdao 266100, China. [email protected] Department of Epidemiology and Biostatistics School of Public Health Tianjin Medical University Tianjin China Department of Pathology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China Peace Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, People’s Republic of China; Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, PR China. State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Datun Road 15, Beijing 100101, China; Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA Department of Radiation Oncology State Key Laboratory of Oncology in Southern China Cancer Center Sun Yat‐sen University Guangzhou People's Republic of China The Sixth Affiliated Hospital of Kunming Medical University (The People’s Hospital of Yuxi City), Yuxi City, Yunnan, China Hebei Medical University-National University of Ireland Galway Stem Cell Research Center, Hebei Medical University , Shijiazhuang , Hebei Province 050017 , China; Hebei Research Center for Stem Cell Medical Translational Engineering , Shijiazhuang , Hebei Province 050017 , China; Human Anatomy Department , Hebei Medical University , Shijiazhuang , Hebei Province 050017 , China Department of Thoracic Surgery First Affiliated Hospital of Sun Yat‐Sen Univesity Guangdong China International School for Optoelectronic Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, China Department of Orthopaedic Surgery, Shanghai Changzheng Hospital Second Military Medical University Shanghai China State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China; The Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China Institute of Children and Adolescent Health, Peking University Health Science Center, Beijing 100191, China East Hospital, and Department of Nephrology, Tongji Hospital; Tongji University School of Medicine, Shanghai, China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China Center for Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China (mainland) Department of Neurosurgery, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, People's Republic of China; National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, People's Republic of China Xijie Wang, Bin Dong, Yinghua Ma, Zhiyong Zou, Jun Ma, and Zhaogeng Yang are with the Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, PR China. Sizhe Huang is with Zhongshan Health Care Centers for Primary and Secondary School, Zhongshan, PR China. Zhiqiang Wang is with the Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia. State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Beijing 100029 P. R. China School of Science, Nanjing University of Science and Technology Department of Medicine and Institute of Health Research and Policy, University of Illinois at Chicago, Chicago, IL, USA Department of Cardiology West China Hospital Sichuan University Chengdu China State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150001, China School of Automation and Electrical Engineering, Dalian Jiaotong University, Dalian 116028, China College of Acupuncture-moxibustion and Orthopedics, Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion, Wuhan 430065, China. Tianjin Medical University, Tianjin, China Key Laboratory of Aquatic Organism Reproduction and Development, Ministry of Education, Key Laboratory of Aquatic Science of Chongqing 1 , and 2; Laboratory of Molecular Developmental Biology, School of Life Science, Southwest University, Beibei, 400715 Chongqing, China 1 , and 2; Key Laboratory of Aquatic Organism Reproduction and Development, Ministry of Education, Key Laboratory of Aquatic Science of Chongqing 1 , and 2; Laboratory of Molecular Developmental Biology, School of Life Science, Southwest University, Beibei, 400715 Chongqing, China 1 , and 2 Department of Hepatic Surgery, Chaoyang Hospital, Capital Medical University, Beijing 100020, China. Department of Cardiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, P. R. China College of Pharmacy, Gansu University of Chinese Medicine, Dingxi East Road 35, Chenguan District, Lanzhou, Gansu Province 730000, China Department of Thoracic Surgery, Shanxi Province People’s Hospital, Taiyuan, People’s Republic of China Department of Integrated Traditional Chinese and Western Medicine, Zhongshan Hospital, Fudan University, Shanghai, China Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, PR China Department of Chemical, Biological and Bio-Engineering, North Carolina Agricultural and Technical State University, 1601 East Market Street, Greensboro, North Carolina 27411, United States; NSF-ERC for Revolutionizing Metallic Biomaterial, North Carolina Agricultural and Technical State University, 1601 East Market Street, Greensboro, North Carolina 27411, United States Vitoux Program on Aging and Prevention, Department of Medicine, University of Illinois Chicago , 1747 W. Roosevelt Rd, Room 586 (MC 275), Chicago, IL 60608, USA Qingdao Industrial Energy Storage Technology Institute, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, P. R. China Division of Genetic Medicine, Department of Internal Medicine University of Michigan Ann Arbor MI USA; Life Sciences Institute, University of Michigan Ann Arbor MI USA Department of Orthopedic Surgery West China Hospital, West China Medical School, Sichuan University The Institute of Child and Adolescent Health, Peking University Health Science Center, Beijing 100191, China. Email: [email protected]. Department of Anesthesiology West China Hospital of Sichuan University No. 37 Guoxue Alley, Wuhou District 610041 Chengdu Sichuan China Qingdao Industrial Energy Storage Research Institute; Qingdao Institute of Bioenergy and Bioprocess Technology; Chinese Academy of Sciences; Qingdao 266101; China Department of Burns, Nanfang Hospital, Southern Medical University, Jingxi Street, Baiyun District, Guangzhou 510515, China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China Department of Clinical Laboratory, Wuhan Medical Treatment Center, Wuhan, Hubei Province, P.R. China. Department of Chemistry, University of Connecticut, 55 North Eagleville Road U3060, Storrs, Connecticut 06269, United States College of Basic Medical Sciences Hubei University of Chinese Medicine Wuhan People's Republic of China School of Municipal and Environmental Engineering; State Key Laboratory of Urban Water Resources and Environment; Harbin Institute of Technology; Harbin 150090; P. R. China Department of Orthopedic Surgery, West China Hospital, West China Medical School, Sichuan University, ChengDu, Sichuan Province, People’s Republic of China Institute of Digestive Diseases, Zhengzhou University, Henan 45001, China Key Laboratory of Environmental Medicine and Engineering of Ministry of Education Department of Epidemiology and Health Statistics School of Public Health Southeast University Nanjing China Division of Academic Internal Medicine and Geriatrics, University of Illinois Chicago, Chicago, Illinois; Department of Thoracic Surgery, Tangdu Hospital, Air Force Military University Department of Cardiology, the Second Affiliated Hospital, Wenzhou Medical University, Wenzhou 325000, China College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong Province, China; Key Laboratory of Zoonosis Prevention and Control of Guangdong, Guangzhou 510642, Guangdong Province, China Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China Department of Hematology, Harbin Institute of Hematology and Oncology, Harbin, Heilongjiang, China Institute of Child and Adolescent Health, Peking University School of Public Health; National Health Commission Key Laboratory of Reproductive Health, Beijing, China (Z.Z., B.D., Y.M., J.M., G.C.P).; National Health Commission Key Laboratory of Reproductive Health, Beijing, China (Z.Z., B.D., Y.M., J.M., G.C.P.). Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China Department of Diving Medicine, Naval Medical Research Institute, Shanghai, PR China. Division of Hepatobiliary and Pancreatic Surgery Department of Surgery The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Peoples Republic of China; NHC Key Laboratory of Combined Multi‐organ Transplantation Hangzhou Peoples Republic of China; Key Laboratory of the diagnosis and treatment of organ Transplantation Research Unit of Collaborative Diagnosis and Treatment For Hepatobiliary and Pancreatic Cancer Chinese Academy of Medical Sciences (2019RU019) Hangzhou Peoples Republic of China; Key Laboratory of Organ Transplantation Research Center for Diagnosis and Treatment of Hepatobiliary Diseases Hangzhou Zhejiang Province Peoples Republic of China Eye Institute, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200031, P.R. China School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, P. R. China; National Engineering Research Center of Urban Water Resources, Harbin 150090, P. R. China Hefei National Laboratory for Physical Sciences at the Microscale, National Synchrotron Radiation Laboratory, iChEM, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, China Division of Developmental Biology, Children's Hospital Research Foundation, Cincinnati, Ohio 45229 Division of Biomedical Informatics, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, Ohio, United States of America; Division of Developmental Biology, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, Ohio, United States of America School of Municipal and Environmental Engineering, Harbin Institute of Technology, 202 Haihe Road, Harbin 150090, People’s Republic of China, and School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080, People’s Republic of China Department of Chemistry, Lanzhou University, Lanzhou 730000, China. Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Colloid and Interface and Thermodynamics, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China Anesthesia Center Capital Medical University Affiliated Beijing Anzhen Hospital Beijing China Rice Research Institute Sichuan Agriculture University Chengdu P.R. China Seed Science and Technology Lab, College of Life Sciences South China Agricultural University Guangzhou 510642 China Institute of Child and Adolescent Health, School of Public Health, Peking University; Email: [email protected]. Shenzhen Geim Graphene Center Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen 518055 China Qingdao Industrial Energy Storage Research Institute, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Colloid and Interface and Thermodynamics CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Department of Radiation Oncology, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, China College of Environment, Nanjing Tech University, Nanjing, People’s Republic of China Dept. of Epidemiology, School of Public Health, Wannan Medical College, Wuhu, China. Detachment Criminal of Public Security Bureau of Changzhou, Changzhou, Jiangsu, China. [email protected] School of Chemical Engineering and Technology; Tianjin University; Tianjin; China; National Engineering Research Center of Distillation Technology Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States Hainan Key Laboratory for Conservation and Utilization of Tropical Marine Fishery Resources, College of Life Science and Ecology, Hainan Tropical Ocean University, Sanya, PR China; Rice Cultivation Laboratory, Rice Research Institute, Sichuan Agricultural University, Chengdu 611130, China; Crop Ecophysiology and Cultivation Key Laboratory of Sichuan Province, Chengdu 611130, China Authors' Affiliations: 1Nanjing Medical University, The Key Laboratory of Cancer Biomarkers, Prevention & Treatment Cancer Center, The Key Laboratory of Antibody Technique of Ministry of Health and The Second Affiliated Hospital, Department of Otolaryngology Head and Neck Surgery, Nanjing; 2Department of Otolaryngology Head and Neck Surgery, Jiangsu Provincial Official Hospital; 3Huadong Medical Institute of Biotechniques, Nanjing; 4Department of Otolaryngology Head and Neck Surgery, Xuzhou Center Hospital, Xuzhou; and 5Department of Otolaryngology Head and Neck Surgery, Yiji Shang Hospital of Wannan Medical College, Anhui, China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China Department of Urology, Qingdao Central Hospital, Qingdao, Shandong 266042, P.R. China National Engineering Research Center of Urban Water Resources, State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology, Harbin 150090, China, and Department of Urban and Civil Engineering, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen 518055, China Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, People’s Republic of China Collaborative Innovation Center of Cancer Medicine, Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, Guangdong, China State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China Affiliations of authors: Service de Biostatistique et d’Epidémiologie, Gustave Roussy Cancer Campus, Villejuif, France (FR, JPP, SM, JL, PB, SM); INSERM U1018, CESP, Université Paris-Sud, Université Paris-Saclay, Villejuif, France (FR, JPP, SM, PB, SM); Ligue Nationale Contre le Cancer Meta-Analysis Platform, Gustave Roussy Cancer Campus, Villejuif, France (FR, JPP, JL, SM); Centre Hospitalier Universitaire Vaudois, Lau Beijing National Laboratory for Molecular Sciences (BNLMS) CAS Key Laboratory of Colloid and Interface and Thermodynamics Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P.R. China Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China. State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, People’s Republic of China National & Local Joint Engineering Laboratory for Optical Conversion Materials and Technology, Lanzhou University, Lanzhou 730000, P. R. China Institute of Child and Adolescent Health School of Public Health Peking University Beijing China School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China School of Life Sciences and Engineering, Foshan University, Changchun, China From the Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China (Y.D., J.M., Y.S., B.D., Z.W., Z.Y., X.W.); and Stanford Prevention Research Center, Department of Medicine, Stanford University, CA (Y.S., J.J.P.). Department of Radiation Oncology, Sun Yat‐Sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou People's Republic of China Vitoux Program on Aging and Prevention, Department of Medicine, University of Illinois at Chicago, Chicago Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing, PR China; Department of Medicine, University of Illinois at Chicago Department of Nasopharyngeal Carcinoma; Sun Yat-sen University Cancer Center; 651 Dongfeng East Road Guangzhou 510060 People's Republic of China; Department of Radiation Oncology; Sun Yat-sen University Cancer Center; 651 Dongfeng East Road Guangzhou 510060 People's Republic of China Department of Neurobiology, College of Basic Medicine China Medical University Shenyang China; Institute of Pathology and Pathophysiology China Medical University Shenyang China Department of Nephrology, Jing'an District Center Hospital of Shanghai, Fudan University, Shanghai 200040, P.R. China Graduate Program in Molecular and Developmental Biology, Division of Developmental Biology, Children's Hospital Research Foundation, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 Hong-Hu Zhu, Hao Jiang, and Xiao-Jun Huang, Peking University People's Hospital, Beijing; De-Pei Wu, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu; Jie Jin, First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang; Jian-Yong Li, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing; Jun Ma, Harbin Institute of Hematology and Oncology, Harbin; Jian-Xiang Wang, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of... Eye Institute Eye & ENT Hospital Fudan University Shanghai China Palo Alto Medical Foundation Research Institute, Palo Alto, CA, USA; Stanford University School of Medicine, Stanford, CA, USA College of Landscape Architecture, Sichuan Agricultural University, Chengdu, Sichuan, China Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, People’s Republic of China Department of Radiology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Tiantan Xili No. 6, Beijing 100050, China Palo Alto Medical Foundation Research Institute, Palo Alto, California.; Stanford Prevention Research Center, Stanford University School of Medicine, Palo Alto, California. Key Laboratory of Coal Clean Conversion & Chemical Engineering Process (Xinjiang Uyghur Autonomous Region), College of Chemical Engineering, Xinjiang University, Urumqi 830046, Xinjiang, China Harbin Institute of Hematology and Oncology Harbin China School of Chemical Science and Engineering, Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai 200092, China Key Laboratory of Luminescent and Real-Time Analytical Chemistry; Ministry of Education; College of Chemistry and Chemical Engineering; Southwest University; Chongqing 400715, China Harbin Institute of Hematology & Oncology, Harbin, China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China, and Environmental Science and Engineering Research Center, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, China Department of Burns, Nanfang Hospital, Southern Medical University, Jingxi Street, Baiyun District, Guangzhou, 510515, China Department of Radiation Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Guangzhou China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China and National Engineering Research Center of Urban Water Resources, Harbin 150090, China Daqing Oilfield Design Institute Co., Ltd., Daqing, Heilongjiang 163712, PR China Division of Developmental Biology, Children’s Hospital Research Foundation, and Graduate Program in Developmental Biology, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229 Laboratoire de Chimie Physique, CNRS/Université Paris-Sud, Bâtiment 349, 91405 Orsay, France Department of Radiology, The Affiliated Hospital of Beihua University, Jilin 132011, P.R. China School of Municipal and Environmental Engineering, Harbin Institute of Technology, 202 Haihe Road, Harbin 150090, People’s Republic of China, School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080, People’s Republic of China, National Engineering Research Center of Urban Water Resources, State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology, Harbin 150090, People’s Republic of China Department of Radiation Oncology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061 P. R. China Department of Orthopedics Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200080 P. R. China Clean Nano Energy Center State Key Laboratory of Metastable Materials Science and Technology Yanshan University Qinhuangdao 066004 P. R. China Department of Orthopedics Changzheng Hospital Second Military Medical University Shanghai China Division of Developmental Biology, Children’s Hospital Research Foundation, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA Department of Orthopedics Central Theater Command General Hospital of the Chinese People's Liberation Army Wuhan China Department of Neurobiology; College of Basic Medicine; China Medical University; Shenyang People's Republic of China; Institute of Pathology and Pathophysiology; China Medical University; Shenyang People's Republic of China State Key Laboratory of Urban Water Resource and Environment (SKLUWRE) School of Environment Harbin Institute of Technology Harbin 150090 China College of Energy and Environmental Engineering, Hebei University of Engineering, Handan 056038, People's Republic of China; Hebei Technology Innovation Center for Water Pollution Control and Water Ecological Remediation, Hebei University of Engineering, Handan 056038, People's Republic of China Digestive Disease Institute, Department of Digestive Disease, the Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450003, China. Tsinghua‐Berkeley Shenzhen Institute & Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen 518055 China The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute for Cancer Research, School of Life Science & Technology, Xi'an Jiaotong University, Xi'an, 710061, China. Department for Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R. China Department of Orthopedics, Changzheng Hospital, Second Military Medical University (Naval Medical University), Shanghai State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China Department of Oncology, Huai'an Hospital of Chinese Medicine, Affiliated to Huai'an Hospital of Nanjing University of Chinese Medicine Huai'an 223001, Jiangsu Province, China. Jiangsu Hansoh Pharmaceutical Group Co. Ltd. Lianyungang Jiangsu Province China Vanderbilt University Institute of Imaging Science Nashville Tennessee USA; Department of Biomedical Engineering Vanderbilt University Nashville Tennessee USA National Engineering Research Center of Urban Water Resources, State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology, Harbin 150090, China, and Department of Urban and Civil Engineering, Harbin Institute of Technology Shenzhen Graduate, Shenzhen 518055, China Institut Charles Sadron (ICS, CNRS, UPR 22). Université de Strasbourg College of Landscape Architecture, Sichuan Agricultural University, Chengdu 611100, China Imaging Center of Neuroscience, Beijing Tian Tan Hospital, Capital Medical University Beijing, China. School of Environment Harbin Institute of Technology Harbin 150090 P. R. China *Laboratory of Molecular and Tumor Immunology, Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Cancer Center and Providence Portland Medical Center, Portland, OR 97213; Departments of; ¶Institute of Immunopathology, School of Life Science, Xi’an Jiaotong University, Xi’an, China; and Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, People's Republic of China Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA; Palo Alto Medical Foundation Research Institute, Palo Alto, CA, USA Division of Biomedical Informatics, Cincinnati Children’s Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.; Division of Developmental Biology, Cincinnati Children’s Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Department of Geriatric Neurology Qilu Hospital of Shandong University Jinan Shandong Province China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Canton, Guangdong, China Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China Clinic and Research Center of Tuberculosis; Shanghai Key Lab of Tuberculosis; Shanghai Pulmonary Hospital; Tongji University School of Medicine; Shanghai 200433 Department of Thoracic Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, P.R. China Laboratoire de Chimie Physique/ELYSE, UMR 8000 CNRS/Université Paris-Sud 11, Faculté des Sciences d’Orsay, Bât. 349, 91405 Orsay Cedex, France Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL Division of Epidemiology and Biostatistics, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang, China Department of Gastrointenstinal Surgery School of Laboratory Medicine, Wannan Medical College, Wuhu City, Anhui Province, China Department of Materials Science and Engineering School of Innovation and Entrepreneurship Southern University of Science and Technology Shenzhen 518055 P. R. China Qingdao Industrial Energy Storage Research Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences 266101 Qingdao China Key Laboratory of Veterinary Vaccine Innovation of the Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou, People's Republic of China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, PR China. Harbin Institute of Hematology and Oncology, Harbin, China Department of Neurosurgery, Shaoxing Central Hospital Shaoxing, 312003, China. Divisions of Biomedical Informatics and Developmental Biology, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA Palo Alto Medical Foundation Research Institute, Palo Alto, CA, USA. Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China Laboratoire de Chimie Physique/ELYSE, Univ. Paris-Sud/CNR/Université Paris-Saclay, Orsay 901405, France Department of Orthopedics, Ningxia People's Hospital Yinchuan 750002, Ningxia, China. Research Institute, Palo Alto Medical Foundation Palo Alto California USA; Department of Health Policy and Administration School of Public Health, and Division of Academic Internal Medicine and Geriatrics, Department of Medicine, College of Medicine, University of Illinois at Chicago Chicago Illinois USA Optics and Optoelectronics Laboratory, Ocean University of China, Qingdao 266100, China. [email protected] State Key Lab of Urban Water Resource and Environment (HIT), Harbin Institute of Technology, Harbin, P. R. China, and National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, Harbin, P. R. China State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, P.R, China Shanghai Key Lab of Chemical Assessment and Sustainability, Department of Chemistry, Tongji University, 1239 Siping Road, Shanghai 200092, P. R. China Hefei National Laboratory for Physical Sciences at the Microscale, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), School of Chemistry and Materials Science, and National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui 230026, China State Key Laboratory of Urban Water Resources and Environment; Harbin Institute of Technology; Harbin; China Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan 430074, China; Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China Department of Gastrointestinal & Pancreatic Surgery, Key Laboratory of Gastroenterology of Zhejiang Province, Zhejiang Provincial People's Hospital People's Hospital of Hangzhou Medical College 158 Shangtang Road 310014 Hangzhou Zhejiang Province China Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics – Hubei Bioinformatics & Molecular Imaging Key Laboratory; Department of Biomedical Engineering; College of Life Science and Technology; Huazhong University of Science and Technology; Hubei Department of Orthopaedic surgery Shanghai Changzheng Hospital Second Military Medical University Shanghai China Department of Anesthesiology, Anhui Provincial Hospital, the First Affiliated Hospital of University of Science and Technology of China, Hefei, China Department of Cardiothoracic Surgery, College of Clinical Medicine, Yangzhou University, Yangzhou, China; The Research Center for Translational Medicine, Yangzhou University, Yangzhou, China Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China Bioinformatics Research Center, North Carolina State University. Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China Institute of Child and Adolescent Health, School of Public Health, Peking University; Beijing China Department of Molecular, Cellular, and Developmental Biology, and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109-2216 Digestive Endoscopy Center, Shanghai Tongren Hospital of Shanghai Jiao Tong University School of Medicine Shanghai 200336, P. R. China. 2Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Institute of Child and Adolescent Health, School of Public Health, Peking University Beijing China; National Health Commission Key Laboratory of Reproductive Health Beijing China Center for Reproduction and Genetic, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China Department of Mechanical Science and Engineering and ‡Department of Materials Science and Engineering, University of Illinois, Urbana−Champaign, Urbana, Illinois, United States Institute of Child and Adolescent Health School of Public Health Peking University Health Science Center Beijing China Department of Medicine, Institute for Health Research and Policy, and Center for Health Behavioral Research, University of Illinois at Chicago, Chicago, IL, USA College of Chemistry and Materials Science; Sichuan Normal University; Chengdu 610066; P. R. China; Key Laboratory of Land Resources Evaluation and Monitoring in Southwest Graduate School of Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China; Laboratory of Microbial Molecular Physiology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Feng-Lin Road, Shanghai 200032, China School of Public Health, Shanxi Medical University, Taiyuan 030001, China. Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Sun Yat‐sen University Cancer Center Guangzhou China Shenzhen Geim Graphene Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China Hebei Medical University-National University of Ireland Galway Stem Cell Research Center , Hebei Medical University , Shijiazhuang, 050017 , Hebei Province , China; Hebei Research Center for Stem Cell Medical Translational Engineering , Shijiazhuang, 050017 , Hebei Province , China; China Human Anatomy Department , Hebei Medical University , Shijiazhuang, 050017 , Hebei Province , China Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong Province, China Qingdao Industrial Energy Storage Research Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao 266101 China Department of Hepatobiliary Surgery, Beijing Chao-Yang Hospital, Beijing 100020, China. Institute of Quality Standard and Testing Technology for Agro-Products; Chinese Academy of Agricultural Sciences; Beijing 100081; P.R China College of Grassland Science, Gansu Agricultural University, Gansu, China Department of Radiology, Shanghai Pneumology Hospital, Shanghai 200433, China. Jiangsu Cowin Biotechnology Co., Ltd., Taizhou, Jiangsu, China [email protected] [email protected]. College of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China Department of Pathology, Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530007, P.R. China 1National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China. School of Municipal and Environmental Engineering, Harbin Institute of Technology, PO Box 2627, Harbin 150090, China State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, People’s Republic of China Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese Medical University, Hangzhou 310000, China; Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, Department of Orthopaedics, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, China Key Laboratory of Utilization and Conservation for Tropical Marine Bioresources of Ministry of Education Sanya China; Hainan Key Laboratory for Conservation and Utilization of Tropical Marine Fishery Resources Sanya China; Yazhou Bay Innovation Institute Sanya China; Hainan Tropical Ocean University Sanya China Key Laboratory of Medical Electrophysiology, Ministry of Education, Department of Cardiology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, China. Key Laboratory of Molecular and Cytogenetics College of Life Sciences and Technology, Harbin Normal University Heilongjiang Province China Department of Mathematics and Statistics, Macquarie University, NSW, Australia 1Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, P.R. China. 1Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology, South China; Collaborative Innovation Center of Cancer Medicine, Guangzhou, PR China. Department of Biomedical Sciences and Institute of Industrial Crops, Heilongjiang Academy of Agricultural Sciences Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, PR China. Department of Biology, University of Pennsylvania, Philadelphia, PA 19104,USA. Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, United States Department of Hepatobiliary Surgery, Beijing Chao‑Yang Hospital, Capital Medical University, Beijing 100020, P.R. China Optics & Optoelectronics Laboratory, Ocean University of China, Qingdao 266100, China. [email protected] 1Department of Radiation Oncology and State Key Laboratory of Oncology in Southern China, Qingdao Industrial Energy Storage Research Institute, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, P. R. China Department of Thoracic Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin 300052, Tianjin, China; Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin 300052, Tianjin, China Hubei Key Laboratory of Advanced Textile Materials & Application, Hubei International Scientific and Technological Cooperation Base of Intelligent Textile Materials & Application, Wuhan Textile University, Wuhan 430200, China Division of Biomedical Informatics, Cincinnati Children's Research Foundation, Cincinnati, OH; Division of Developmental Biology, Cincinnati Children's Research Foundation, Cincinnati, OH Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Institute of Photonics Technology, Jinan University, Guangzhou 511443, China Department of Radiation Oncology Sun Yat‐sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.; Department of Biology, University of Pennsylvania, 433 South University Avenue, Philadelphia, PA, USA. Renal Division, Department of Medicine, Peking University First Hospital, Beijing 100034, China; Institute of Nephrology, Peking University, Beijing 100034, China; Key Laboratory of Renal Disease, National Health Commission of China, Beijing 100034, China; Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, Beijing 100034, China; Research Units of Diagnosis and Treatment of Immune-Mediated Kidney Diseases, Chinese Academy of Medical Sciences, Beijing 100034, China Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun 130012, China Hebei Medical University-National University of Ireland Galway Stem Cell Research Center, Hebei Medical University, Shijiazhuang, China. National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence; Peking University; Beijing 100191 China; School of Public Health; Peking University; Beijing 100191 China Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communication, Institute of Photonics Technology, Jinan University, Guangzhou 511443, China Department of Tuberculosis and Shanghai Key Lab of Tuberculosis, Shanghai Pulmonary Hospital Affiliated to Tongji University School of Medicine 507 Zhengmin Road, Shanghai 200433, China. Key laboratory of Molecular Epigenetics Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, China College of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, P. R. China Department of Urological Surgery, Kunshan Hospital of TCM, Kunshan, Jiangsu 215300, P.R. China Institute of Child and Adolescent Health & School of Public Health, Peking University Health Science Center, Beijing, China (X.W., Z.Y., Y.D., B.D., J.M.). Laboratoire de Chimie Physique, CNRS/Université Paris-Sud 11, Bâtiment 349, 91405 Orsay, France Beijing Key Laboratory of Forest Food Process and Safety, Department of Food Science and Engineering, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, People’s Republic of China Hebei Medical University-National University of Ireland Galway Stem Cell Research Center, Hebei Medical University, Shijiazhuang, 050017, Hebei Province, China; Hebei Research Center for Stem Cell Medical Translational Engineering, Shijiazhuang, 050017, Hebei Province, China; Human Anatomy Department, Hebei Medical University, Shijiazhuang, 050017, Hebei Province Beijing National Laboratory for Molecular Sciences, Key Laboratory of Colloid and Interface and Thermodynamic, Institute of Chemistry, Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing 100190 China Department of Health Statistics, College of Public Health, Tianjin Medical University, Tianjin 300070, China Department of Urban Planning and Design, The University of Hong Kong, Hong Kong 999077, China Department of Medicine, Institute for Health Research and Policy, and Center for Behavioral Research, University of Illinois Chicago, Chicago, Illinois State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China. State Key Laboratory of Urban Water Resource and Environment; Harbin Institute of Technology; Harbin 150090; P. R. China Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150090, China Advanced Biomaterials and Tissue Engineering Center Huazhong University of Science and Technology Wuhan 430074 People's Republic of China School of Chemistry and Chemical Engineering Shanghai Jiao Tong University Shanghai 200240 China State Key Laboratory for Agrobiotechnology, Key Laboratory of Crop Heterosis and Utilization (MOE), Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University , Beijing , China The Affiliated Suqian First People’s Hospital of Nanjing Medical University, Suqian, Jiangsu, China (mainland) State Key Laboratory of Chemical Resource Engineering Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 China Key Laboratory of Crop Germplasm Resources of Hebei, Agricultural University of Hebei Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons of Columbia University, 701 West 168th Street, New York, New York 10032, and Department of Neurology, University of Miami School of Medicine, 1501 NW 9th Avenue, Miami, Florida 33136 Department of Veterinary Surgery, College of Veterinary Medicine Northeast Agricultural University Harbin P. R. China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine Northeast Agricultural University Harbin P. R. China Department of Cardio‑Thoracic Surgery, The First Hospital of Longyan City, Fujian Medical University, Longyan, Fujian 364000, P.R. China Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, People’s Republic of China; Institute of Pathology and Pathophysiology, China Medical University, Shenyang, People’s Republic of China 1Department of Medical Microbiology, Immunology and Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine, 913 N. Rutledge Street, Springfield, IL 62794, USA Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, People’s Republic of China State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin, People’s Republic of China Department of Neurobiology School of Life Sciences, China Medical University Shenyang China; Key Laboratory of Cell Biology Ministry of Public Health of China, China Medical University Shenyang China; Key Laboratory of Medical Cell Biology Ministry of Education of China, China Medical University Shenyang China Department of Orthopaedics West China Hospital, Sichuan University Chengdu China Institute of Child and Adolescent Health, School of Public Health Peking University Health Science Center Beijing People's Republic of China Department of Anesthesiology West China Hospital Sichuan University Chengdu Sichuan China College of Agronomy/National Key Laboratory of Crop Biology Shandong Agricultural University Tai'an 271018 China Department of Radiation Oncology State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Sun Yat‐Sen University Cancer Center Collaborative Innovation Center for Cancer Medicine Guangzhou People’s Republic of China Department of Orthopaedic Surgery Shanghai Changzheng Hospital Second Military Medical University Shanghai China School of Engineering, University of South Australia, Mawson Lakes, South Australia 5095, Australia Animal Science and Technology School Henan University of Science and Technology Luoyang China Department of Radiation Oncology, Sun Yat‐sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Guangzhou Guangdong 510060 P. R. China Department of Medical Microbiology, Immunology and Cell Biology, Simmons Cancer Institute Southern Illinois University School of Medicine Springfield Illinois Department of Health Statistics, College of Public Health, Tianjin Medical University, Tianjin 300070, P.R. China Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China Qingdao Industrial Energy Storage Research Institute, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, China National Engineering Research Center for Miniaturized Detection Systems, College of Life Science, Northwest University, Xi'an, PR China Department of General Surgery Jinhu People's Hospital Huai'an China Chongqing Key Laboratory of Biomedical Analysis (Southwest University), Chongqing Science & Technology Commission, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400716, PR China Department of Colorectal Surgery, Changhai Hospital, Navy Medical University, Shanghai 200433, China. [email protected]. Tsinghua Shenzhen International Graduate School &Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen 518055, China Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, People's Republic of China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, the State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, China; Center for Precision Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, People’s Republic of China Laboratoire de Chimie Physique, UMR 8000 CNRS-Université Paris-Sud, ELYSE, Bât. 349, 91405 Orsay, France Key Laboratory of Semiconductors and Applications of Fujian Province, Semiconductor Photonics Research Center, Department of Physics, Xiamen University, Xiamen 361005, People’s Republic of China 1Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China. From the Departments of Nasopharyngeal Carcinoma and Radiation Oncology, Cancer Center, Sun Yat-sen University of Medical Sciences, Guangzhou, People’s Republic of China. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Baylor College of Medicine School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150001, China Department of Cardiology, Tongji Hospital, Heart Rhythm Research Center, and Institute of Medical Genetics, Tongji University, Shanghai 200065, China Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015. Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, China State Key Laboratory of Urban Water Resource and Environment, School of Environments, Harbin Institute of Technology, Harbin 150090, China Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas School of Chemistry and Materials Science University of Science and Technology of China Hefei Anhui 230026 P. R. China Department of Gastroenterology, Affiliated Foshan Hospital of Southern Medical University, Foshan 528000, China National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin 300070, China State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, People’s Republic of China Department of Gastrointestinal Surgery, Liuzhou People’s Hospital, Liuzhou 545006, Guangxi, China Department of Cardiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China Laboratoire de Chimie Physique, CNRS/Université Paris-Sud, Bât. 349, 91405 Orsay, France Beijing National Laboratory for Molecular Sciences Key Laboratory of Colloid and Interface and Thermodynamics, Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Department of Medicine, University of Illinois, Chicago State Key Laboratory of Oncology in South China Department of Radiation Oncology Sun Yat‐sen University Cancer Center Guangzhou People's Republic of China *Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048;; †Biomedical Science and Translational Medicine Graduate Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048; Department of Urology, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, Jiangsu, China (mainland) Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing 100191, China. Department of Nuclear Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, P. R. China Sun Yat-Sen University Cancer Center, The State Key Laboratory of Oncology in South China, Guangzhou, China Department of Oncology, Huai’an TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Huai’an, P.R. China Key Laboratory of Molecular Epigenetics Institute of Genetics and Cytology, Northeast Normal University Changchun 130021 China Department of Biological Sciences, Lehman College, and The Graduate Center, The City University of New York, 250 Bedford Park Boulevard West, Bronx, New York 10468, and Department of Neurology, University of Miami School of Medicine, 1501 N.W. 9th Avenue, Miami, Florida 33136 Department of Mathematics and Statistics Macquarie University Macquarie Park New South Wales Australia Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China Department of Chemistry, University of Wisconsin−Milwaukee, Milwaukee, Wisconsin 53201 Department of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu. Qingdao Industrial Energy Storage Research Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences No. 189 Songling Road Qingdao 266101 China State Key Laboratory of Urban Water Resource and Environment, National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, Harbin 150090, China, and Environmental Science and Engineering Research Center, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen 518055, China Laboratory of Physical Chemistry, ETH Zurich , Vladimir-Prelog-Weg 2, 8093 Zurich, Switzerland Qingdao Industrial Energy Storage Research Institute; Qingdao Institute of Bioenergy and Bioprocess Technology; Chinese Academy of Sciences; Qingdao; P. R. China Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Lianyungang, P.R. China; Department of Research and Development, Shenzhen Wanhe Pharmaceutical Co., Ltd., Shenzhen, China; Division of Medical Genetics and Genomics, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. [email protected]. Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. [email protected]. Division of Developmental Biology, Cincinnati Children's Research Foundation, Cincinnati, OH, USA. [email protected]. Division of Biomedical Informatics, Cincinnati Children's Research Foundation, Cincinnati, OH, USA. [email protected]. Laboratory of Systems Developmental Biology, Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. [email protected]. Palo Alto Medical Foundation Research Institute, Palo Alto, California; Department of Medicine Department of Cardiology, Renji Hospital, Shanghai Jiaotong University School of Medicine Department of Epidemiology and Biostatistics, School of Public Health and Management Wenzhou Medical University Wenzhou China Huaian Affiliated Hospital of Nanjing University of Chinese Medicine, Huaian, Jiangsu, China Department of Health Policy and Administration, Institute for Health Research and Policy, University of Illinois at Chicago, IL, USA In-Situ Center for Physical Sciences, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, People’s Republic of China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, Guangdong, China Department of Urinary Surgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China. MOE Key Laboratory of Arid and Grassland Ecology, School of Life Sciences, Lanzhou University, 298 Tian Shui Road, Lanzhou, 730000, P. R. China Department of Chemical, Biological and Bio‐Engineering North Carolina Agricultural and Technical State University Greensboro North Carolina 27411; NSF‐ERC For Revolutionizing Metallic Biomaterial, North Carolina Agricultural and Technical State University Greensboro North Carolina 27411 *F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048;; †Biomedical Science and Translational Medicine Graduate Program, Cedars-Sinai Medical Center, Los Angeles, CA 90048; and Department of Veterinary Surgery College of Veterinary Medicine Northeast Agricultural University Harbin China Department of Emergency Medicine, South Campus, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Department of Thoracic surgery, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, China Tsinghua-Berkeley Shenzhen Institute and Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China Harbin Institute of Hematology & Oncology, Harbin 150010, China. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, China; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China. Research Center, Eye and ENT Hospital of Fudan University, Shanghai, China. College of Agronomy and Biotechnology, China Agricultural University, Beijing, 100094, China Department of Thoracic surgery Heji Hospital Affiliated to Changzhi Medical College Changzhi China State Key Laboratory of Urban Water Resource and Environment; Harbin Institute of Technology; Harbin 150080, China Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China. Medical College of Linyi University, Linyi 276000, P.R. China 15Department of Radiation Oncology, Anhui Provincial Hospital, Hefei, China. Hebei Medical University-Galway University of Ireland Stem Cell Research Center, Hebei Medical University, Hebei, China; Hebei Research Center for Stem Cell Medical Translational Engineering, Hebei, China; Hebei Technology Innovation Center for Stem Cell and Regenerative Medicine, Hebei, China Department of Orthopedics, Changzheng Hospital, Shanghai, China. State Key Laboratory of Oncology in Southern China Department of Radiation Oncology Cancer Center Sun Yat‐sen University Guangzhou People's Republic of China Laureen Ribassin-Majed, Sophie Marguet, Jean Pierre Pignon, and Pierre Blanchard, Ligue Nationale Contre le Cancer meta-analysis platform, Gustave-Roussy, Université Paris-Saclay; Centre for Research in Epidemiology and Population Health, INSERM U1018, Université Paris-Saclay, Villejuif, France; Anne W.M. Lee and Wai Tong Ng, Pamela Youde Nethersole Eastern Hospital; Anthony T.C. Chan, The Chinese University of Hong Kong; Daniel T.T. Chua, Hong Kong Sanatorium & Hospital; Dora L.W. Kwong, Queen Mary... School of Chemistry and Materials Science Hefei National Research Center for Physical Sciences at the Microscale National Synchrotron Radiation Laboratory School of Nuclear Science and Technology University of Science and Technology of China Hefei Anhui 230026 P. R. China; Suzhou Institute for Advanced Research University of Science and Technology of China Suzhou Jiangsu 215123 P. R. China State Key Laboratory of Urban Water Resource and Environment, School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China Center for Community Health Care Shanghai Jiao Tong University China Hospital Development Institute Shanghai China Department of Hematology, Harbin Institute of Hematology & Oncology, Harbin, China Professeur à l'Université de Nanjin en Chine (Aeronautics et Astronautics). Il a effectué sa thèse et une partie de son post-doctorat au Laboratoire de Chimie Physique. Department of Developmental and Behavioral Pediatrics of Shanghai Children’s Medical Center, XinHua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Children’s Environmental Health, Shanghai 200127, China Orthopedics Research Institute, Department of Orthopedics, National Clinical Research Center for Geriatrics West China Hospital, Sichuan University Chengdu Sichuan China Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China; Department of Orthopedic Surgery, The 72nd Military Hospital of PLA, Huzhou, China Department of Infectious Diseases, Binzhou City TB Prevention and Control of Hospital, Binzhou, Shandong 251700, P.R. China Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China Division of Nephrology, Jingan District Centre Hospital of Shanghai , Shanghai , China Department of Chemical, Biological and Bio-Engineering, North Carolina Agricultural and Technical State University, Greensboro, NC, USA; NSF Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC, USA Program of Prevention Outcomes and Practices, Stanford Prevention Research Center, Stanford University, CA 94305-5705, USA. Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China Department of Nephrology, Jing’an District Center Hospital of Shanghai, Fudan University, Shanghai, 200040, China Department of Endemic Disease, Kaifeng Center for Disease Control and Prevention, Kaifeng, Henan, P. R. China Department of Health Services Research, Palo Alto Medical Foundation Research Institute, Palo Alto, CA, USA Institute of Forensic Science of Public Security Bureau of Changzhou,Changzhou,Jiangsu 213003,China. Department of Medicine, University of Illinois Chicago, Chicago, IL, USA Department of Health Statistics, College of Public Health, Tianjin Medical University, Tianjin, China. Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, People's Republic of China Institute of Digestive Diseases, Zhengzhou University, Henan, China. Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China; State Key Laboratory of Applied Optics Chuangchun 130033 China Beijing National Laboratory for Molecular Sciences; CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics; Institute of Chemistry; Chinese Academy of Sciences; Beijing 100190 Nanjing University of Science and Technology Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, People’s Republic of China School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China. [email protected] Harbin Hematologic Tumor Institution Harbin People’s Republic of China Eye Institute, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200031, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai 200031, China Department of Molecular Target Medicine , Aichi Medical University, Nagakute, Aichi 480‑1195, Japan Wenzhou Institute University of Chinese Academy of Sciences Wenzhou 325001 P.R. China; State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Changchun 130022 P.R. China Department of Thoracic Surgery The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou China School of Science Nanjing University of Science and Technology Nanjing Jiangsu China Shenzhen Geim Graphene Center, Tsinghua-Berkeley Shenzhen Institute & Tsinghua Shenzhen International Graduate School, Tsinghua University , Shenzhen 518055 , China Cardiovascular Department, the General Hospital of Guangzhou Command, Guangzhou 510010, Guangdong, China. Department of Research, Golden Health Diagnostics Inc., Yancheng, Jiangsu 224000, P.R. China Hefei National Laboratory for Physical Sciences at the Microscale, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Hefei Science Center (CAS) School of Chemistry and Materials Science and USTC Center for Micro- and Nanoscale Research and Fabrication University of Science and Technology of China Hefei Anhui 230026 P. R. China Department of Health Services Research Palo Alto Medical Foundation Research Institute Palo Alto California USA; Stanford Prevention Research Center Stanford University Stanford California USA Department of Anesthesiology, Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Diseases Capital Medical University Beijing 100029 PR China Department of Cardiology, The Second Affiliated Hospital and Yuying Children’s Hospital, Wenzhou Medical University, Xueyuanxi Road, No. 109, Wenzhou, Zhejiang 325000, China Biomedical Applications Group, Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, Pennsylvania Tsinghua Shenzhen International Graduate School Tsinghua University Shenzhen 518055 China Department of Medical Microbiology, Immunology & Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine, 913 North Rutledge Street, Springfield, IL 62794, U.S.A. Hefei National Laboratory for Physical Sciences at the Microscale, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), School of Chemistry and Materials Science, and National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui 230026, People’s Republic of China Department of Radiation Oncology Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing China Department of Radiation Oncology Sun Yat‐sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine 651 Dongfeng Road East Guangzhou 510060 China College of Landscape Architecture, Sichuan Agricultural University, Chengdu 625014, China School of Public Health and Institute of Child and Adolescent Health, Peking University. Email: [email protected]. Department of Emergency, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, China Hebei Medical University-National University of Ireland Galway Stem Cell Research Center, Hebei Medical University, Hebei Province, 050017, China; Hebei Research Center for Stem Cell Medical Translational Engineering, Hebei Province, 050017, China; Department of Human Anatomy, Hebei Medical University, Hebei Province, 050017, China Washington Univ. in St. Louis 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China. Hongqiao International Institue of Medicine & Clinical Research Center Tongren Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Institute of Health Research and Policy, University of Illinois at Chicago, Chicago, IL, USA; Department of Medicine, College of Medicine, University of Illinois at Chicago, 1747 W. Roosevelt Rd, Room 586 (MC 275), Chicago, IL 60608, USA Center for Imaging Science, Department of Biomedical Engineering, The Johns Hopkins University, 320 Clark Hall, Baltimore, MD 21218, USA Beijing National Laboratory for Molecular Sciences; CAS Key Laboratory of Colloid and Interface and Thermodynamics; Institute of Chemistry, Chinese Academy of Sciences; Beijing 100190; China Department of Statistics, North Carolina State University, Raleigh, North Carolina 27607, United States; Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27607, United States Institute of Child and Adolescent Health, Peking University School of Public Health, Beijing 100191, China. [email protected] Beijing Anzhen Hospital, Capital Medical University; Center for Anesthesiology; No.2 Anzhen Road Chaoyang District Beijing Beijing China 100029 Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang, People's Republic of China; Institute of Pathology and Pathophysiology, China Medical University, Shenyang, People's Republic of China and Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine Department of Health Services Research, Palo Alto Medical Foundation Research Institute, Palo Alto, CA, USA; Stanford Prevention Research Center, Stanford University School of Medicine, Palo Alto, CA, USA School of Public Health & Institute of Child and Adolescent Health, Peking University, Beijing 100191, China. [email protected] Sun Yat-sen University Cancer Centre, State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangzhou, People's Republic of China Department of Neurobiology College of Life Science China Medical University Shenyang China; Key Laboratory of Cell Biology Ministry of Public Health of China China Medical University Shenyang China; Key Laboratory of Medical Cell Biology Ministry of Education of China China Medical University Shenyang China School of Chemistry and Materials Science University of Science and Technology of China Hefei Anhui 230026 P. R. China; Suzhou Institute for Advanced Research University of Science and Technology of China Suzhou Jiangsu 215123 P. R. China Laboratoire de Chimie Physique/ELYSE; Université Paris-Sud 11; Orsay; France Department of Mathematics and Statistics, Macquarie University, Sydney, Australia *Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115; College of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou, Zhejiang 311300, China; Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, HuZhou University, Huzhou, Zhejiang 313000, China Department of Hematology,Tianjin Medical University General Hospital,Tianjin 300052,China. Northeast Normal University Key Laboratory of Molecular Epigenetics, Ministry of Education and Institute of Cytology and Genetics, , Changchun 130024 , China; Jilin University Department of Oral Anatomy and Physiology, School and Hospital of Stomatology, , Changchun 130021 , China Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, 5100 Paint Branch Parkway, College Park, Maryland 20740, United States Anhui Provincial Hospital, Hefei, China Email: [email protected]. Department of Nephrology, Institute of Nephrology, Shanghai Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China College of Acupuncture-moxibustion and Orthopaedics of Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment of Diseases by Acupuncture-moxibustion, Wuhan 430060, China. Institute of Child and Adolescent Health, School of Public Health Peking University Beijing China; National Health Commission Key Laboratory of Reproductive Health Peking University Beijing China Department of Health Statistics College of Public Health Tianjin Medical University Tianjin China School of Public Health and Institute of Child and Adolescent Health, Peking University, Beijing 100191, China; Email: [email protected]. Institute of Harbin Hematology & Oncology, The First Hospital of Harbin, Harbin 150010, Heilongjiang, China Department of General Surgery, Affiliated Central Hospital, Shenyang Medical College, Shenyang 110024, China. Department of Orthopaedics West China Hospital Sichuan University Chengdu China Institute of Child and Adolescent Health, School of Public Health, Peking University Department of Spine Surgery, Daxing Hospital, Xi’an 710016, Shaanxi, China Division of Academic Internal Medicine and Geriatrics Department of Medicine University of Illinois at Chicago Chicago Illinois USA Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China From Shanghai Institute of Hematology, Department of Hematology, Rui-Jin Hospital and Ren-Ji Hospital, Shanghai Second Medical University, Shanghai, P.R. China; Harbin Institute of Hematology, Harbin Municipal First People's Hospital and the Department of Traditional Chinese Medicine, First Hospital affiliated to Harbin Medical University, Harbin, P.R. China. Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan; Laboratoire de Chimie Physique, UMR 8000 CNRS/Université Paris-Sud, Bât. 349, Orsay 91405 Cedex, France College of Acupuncture-moxibustion and Orthopaedics of Hubei University of Chinese Medicine/Hubei Provincial Collaborative Innovation Center of Preventive Treatment of Diseases by Acupuncture-moxibustion, Wuhan 430060, China. [email protected]. Department of Orthopedics, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China. Department of Cardiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, 150080, People’s Republic of China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, People’s Republic of China, School of Chemistry and Materials Science University of Science and Technology of China Hefei Anhui 230026 China center of Hematology and Oncology,The First Hospital of Harbin, Harbin,150010, Heilongjiang Province, China.E-mail: [email protected]. Department of Radiation Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine Guangzhou China Imaging Center of Neuroscience, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China. Email: [email protected]. School of Engineering; University of South Australia; Australia School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China. Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China Department of Cardiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, No.109 Xueyuan West Road, Lucheng District, Wenzhou 325000, Zhejiang, China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of Technology Harbin 150090 China Optics and Optoelectronics Laboratory, Ocean University of China, Qingdao 266100, P. R. China Optics and Optoelectronics Laboratory, Ocean University of China, Qingdao 266100, China Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China Department of Radiation Oncology, Sun Yat‐sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Guangzhou Guangdong 510060 P. R. China Department of Molecular, Cellular, and Developmental Biology and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109-2216 Department of Pharmacy Lanzhou General Hospital of PLA, No. 333 Binghe South Road Lanzhou Gansu 730050 People's Republic of China School of Integrated Traditional Chinese and Western Medicine, Binzhou Medical University, Yantai 264003, Shandong, China Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China Xiangya School of Nursing, Central South University, Changsha 410013, China Department of Otolaryngology-Head and Neck Surgery, Yiji Shan Hospital, The First Affiliated Hospital of Wannan Medical College No. 92 Zheshan Xi Road, Wuhu 241000, China. 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, P.R. China. The Sixth People’s Hospital of Nantong Economic Crop Research Institute Xinjiang Academy of Agricultural Science Ürümqi Xinjiang 830091 China Hefei National Laboratory for Physical Sciences at the Microscale Collaborative Innovative Center of Chemistry for Energy Materials (iChEM) School of Chemistry and Materials Science National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei Anhui 230026 China Hefei National Laboratory for Physical Sciences at the Microscale Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) School of Chemistry and Materials Science National Synchrotron Radiation Laboratory, and CAS Center for Excellence in Nanoscience University of Science and Technology of China Hefei Anhui 230026 China; Institute of Energy Hefei Comprehensive National Science Center 350 Shushanhu Rd. Hefei Anhui 230031 China Department of Chemistry; and Shanghai Key Lab of Chemical Assessment and Sustainability; Tongji University; Shanghai; China Institute of Child and Adolescent Health, School of Public Health Peking University Beijing China; National Health Commission Key Laboratory of Reproductive Health Beijing China School of Chemical Science and Engineering; Shanghai Key Lab of Chemical Assessment and Sustainability; Tongji University; Shanghai; China Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China; The Second People's Hospital Mudanjiang China Division of Maternal-Fetal Medicine, Departments of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children’s Hospital, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Bioinformatics Research Laboratory, Baylor College of Medicine, Houston, TX 77030, USA. Key Laboratory of Biocontrol Resource Research and Utilization, Ministry of Agriculture, Institute of Biological Control, Chinese Academy of Agricultural Sciences, Beijing 100081, China. [email protected] Department of Chemistry and Biochemistry, University of Wisconsin−Milwaukee, 3210 N. Cramer Street, Milwaukee, Wisconsin 53211 State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Shanghai 200050 China; School of Electronic, Electrical and Communication Engineering University of Chinese Academy of Sciences Beijing 100049 China Department of Neurosurgery Guizhou Provincial People's Hospital Guiyang China Department of Thoracic Surgery, Shanxi Provincial People's Hospital Taiyuan China; Fifth Clinical Medical College Shanxi Medical University Taiyuan People's Republic of China Center for Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, P.R China. Department of Oncology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210028, P.R. China Horticultural Crop Research Institute, Yunnan Academy of Agricultural Sciences, Kunming, Yunnan, 650205, China Department of Veterinary Medicine, Northeast Agricultural University, 59 Mucai Street, Xiangfang District, Harbin 150030, China National Engineering Laboratory for Animal Breeding/Beijing Key Laboratory for Animal Genetic Improvement, China Agricultural University, Beijing, China Department of Abdominal Tumor Surgery, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650118, P.R. China The Brain Science Center Beijing Institute of Basic Medical Sciences Beijing China Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, People's Republic of China Department of Cardiothoracic Surgery, The First Hospital of Longyan City, Longyan, Fujian 364000, P.R. China Department of General Surgery Jinhu People's Hospital Huaian Jiangsu China School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, People’s Republic of China, and State Key Laboratory of Urban Water Resources and Environment, National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, Harbin 150090, People’s Republic of China Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang 110122, China; Institute of Pathology and Pathophysiology, China Medical University, Shenyang 110122, China Division of Developmental Biology, Children’s Hospital Research Foundation, Cincinnati, Ohio 45229; Graduate Program in Developmental Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229 1State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China. School of Chemistry & Chemical Engineering, South China University of Technology, Guangzhou 510640, China Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA; Siemens Healthcare, Hoffman Estates, Chicago, IL 60192, USA Department of Urinary Surgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China Department of Health Services Research; Palo Alto Medical Foundation Research Institute; Palo Alto California USA; Stanford Prevention Research Center; Stanford University School of Medicine; Palo Alto California USA Department of Biopharmaceutical Sciences College of Pharmacy Harbin Medical University‐Daqing Daqing Heilongjiang China Center for Magnetic Resonance Research University of Minnesota Minneapolis Minnesota USA Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, China College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, P. R. China; Key Laboratory of Land Resources Evaluation and Monitoring in Southwest, Sichuan Normal University, Ministry of Education, Chengdu 610066, P. R. China Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science, National Synchrotron Radiation Laboratory, School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui 230026, China; Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou, Jiangsu 215123, China State Key Laboratory of Oncology in South China Sun Yat‐sen University Cancer Center Guangzhou People's Republic of China Department of Research and Development, Shenzhen Wanhe Pharmaceutical Co., Ltd, Shenzhen, China; Epidemiology and Biostatistics Institute School of Public Health Tianjin Medical University Tianjin China Department of Statistics Macquarie University Sydney NSW Australia College of Material Science and Engineering, Hunan University, Hunan, Changsha 410082, P. R. China The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute for Cancer Research, Xi'an Jiaotong University, Xi'an 710061, China. Department of Orthopedics, Changzheng Hospital Second Affiliated Hospital of Second Military Medical University Shanghai People's Republic of China Lanzhou University of Technology 3 Department of Physics, , Lanzhou 730050, China Department of Stomatology, Beijing Changping District Hospital, Beijing, China Department of Biomedical Engineering, University of North Texas, Denton, Texas 76207, United States State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China From the Department of Biopharmaceutical Sciences (C.M., Y. Li, J.M., Y. Liu, Q.L., S.N., L.Z., Z.P., D.Z.), College of Pharmacy, Harbin Medical University, Nangang District, Harbin, Heilongjiang, People's Republic of China; Bio-pharmaceutical Key Laboratory of Heilongjiang Province (D.Z.), Harbin, People's Republic of China; Department of Pharmacology (Z.S.), Harbin Medical University-Daqing, Daqing, Heilongjiang Province, People's Republic of China. Department of Orthopedic Trauma Surgery Shanghai Changzheng Hospital Shanghai China Department of General Practitioners Tongren Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of Orthopedics People's Hospital of Ningxia Hui Autonomous Region Yinchuan Ningxia Province China Department of Oncology, Huai’an TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Huai’an, China Department of Cardiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University General Surgery Department, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan 030032, China; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Department of Respiratory and Critical Care Medicine Dongying People's Hospital Dongying City 257000, Shandong China College of Acupuncture and Orthopedics, Hubei University of Chinese Medicine/Hubei Collaborative Innovation Center for Acupuncture and Moxibustion, Wuhan 430061. [email protected]. School of Life Sciences and Engineering Foshan University Foshan China; Science and Technology Incubator Foshan University Foshan China Palo Alto Medical Foundation Research Institute, 795 El Camino Real, Ames Building, Palo Alto, CA 94301, USA; Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA Vanderbilt University Institute of Imaging Science Nashville TN USA; Department of Biomedical Engineering Vanderbilt University Nashville TN USA Institute of Nuclear Physics and Chemistry; China Academy of Engineering Physics; Mianyang 621900; China Institute of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China College of Landscape Architecture, Sichuan Agricultural University, Chengdu, China Department of Chemistry, Washington University in Saint Louis, One Brookings Drive, Saint Louis, Missouri 63130-4899, United States The College of Humanities, Shandong Management University, Jinan 250357, China Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, China Dalian National Laboratory for Clean Energy Dalian 116023 China; Qingdao Industrial Energy Storage Research Institute Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences No. 189 Songling Road Qingdao 266101 China National Institute on Drug Dependence, Peking University, Beijing, China; School of Public Health, Peking University, Beijing, China The State Key Laboratory of Refractories and Metallurgy, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, China Laboratoire de Chimie Physique/ELYSE, CNRS/Université Paris-Sud, Faculté des Sciences d’Orsay, Bât. 349, 91405 Orsay Cedex, France Qingdao Industrial Energy Storage Research Institute, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, People’s Republic of China 1State Key Laboratory of Oncology in Southern China;; 3Department of Radiation Oncology, Cancer Center, and General Surgery Jinhu People's Hospital Huaian China Department of Integrative Medicine, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian, People’s Republic of China; Xiamen Clinical Research Center for Cancer Therapy, Xiamen, Fujian, People’s Republic of China Key Laboratory for Renewable Energy; Chinese Academy of Sciences; Beijing Key Laboratory for New Energy Materials and Devices; Beijing National Laboratory for Condensed Matter Physics; Institute of Physics Department of Internal Medicine, Section on Nephrology and; Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; and Department of Chemistry & Biochemistry, University of Wisconsin—Milwaukee, 3210 North Cramer Street, Milwaukee, Wisconsin 53211 Beijing HongYun RongTong Technology Co., Ltd Beijing China Harbin Institute of Hematology & Oncology, Harbin the First Hospital, Harbin, China; and Department of Anesthesiology, Beijing Anzhen Hospital of Capital Medical University, Beijing 100029, P.R. China Tsinghua-Berkeley Shenzhen Institute & Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China Department of Medical Microbiology, Immunology and Cell Biology, Simmons Cancer Institute; Southern Illinois University School of Medicine; Springfield Illinois Department of Computer Science, University of Helsinki , 00014 Helsinki, Finland Department of Cardiology, West China Hospital, Sichuan University, 610083; P.R. China Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, Department of Orthopaedics, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China; Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese Medical University, Hangzhou 310000, China Tianjin Medical University, Tianjin 300070, China. E-mail: [email protected]. From the Department of Gynecology and Obstetrics, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shan Xi, China 710 061 Department of Radiology Affiliated Hospital of Beihua University Jilin China College of Marine Life Sciences, Ocean University of China, Qingdao, Shandong 266003, P.R. China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center , Guangzhou, P. R. China; Department of Radiation Oncology, Sun Yat-sen University Cancer Center , Guangzhou, P. R. China From the Department of Digestive Surgery, Shanxi Cancer Hospital, Taiyuan 030013, Shanxi, China; From the Department of Digestive Surgery, Shanxi Cancer Hospital, Taiyuan 030013, Shanxi, China School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, People’s Republic of China, School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080, People’s Republic of China, and State Key Laboratory of Urban Water Resources and Environment, National Engineering Research Center of Urban Water Resources, Harbin Institute of Technology, Harbin 150090, People’s Republic of China College of Computer Science and Technology, Xinjiang University, Urumqi 830017, China; Xinjiang Key Laboratory of Signal Detection and Processing, Xinjiang University, Urumqi 830017, China Institute of Child and Adolescent Health, School of Public Health Peking University Beijing China Department II of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China Clinic and Research Center of Tuberculosis, Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China Department of Endemic Disease, Kaifeng Center for Disease Control and Prevention, Kaifeng, Henan 475004, China Horticultural Research Institute, Yunnan Academy of Agricultural Sciences, Kunming, People’s Republic of China Department of Respiratory Medicine, Nantong Pulmonary Hospital (The Sixth People's Hospital of Nantong), Nantong, China. Laboratory of Microbial Molecular Physiology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Feng-Lin Road, Shanghai 200032, China; Graduate School of Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031, China Research Institute of Economic Crops, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, China The First Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an Shaanxi, 710004, P. R. China. Department of Oncology, Huai'an Second People's Hospital, The Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, Jiangsu 223001, P.R. China Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, Xinhua Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200127, China. Hubei Key Laboratory of Ecological Restoration of River-Lakes and Algal Utilization, Hubei University of Technology, Wuhan, Hubei, China Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science, National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China; Suzhou Institute for Advanced Research, University of Science and Technology of China, Suzhou, Jiangsu 215123, P. R. China Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, BJ, China; National Health Commission Key Laboratory of Reproductive Health, Beijing, BJ, China Zhejiang Chinese Medical University, Hangzhou 310000, China; Department of Orthopaedics, Jiaxing Key Laboratory of Basic Research and Clinical Translation on Orthopedic Biomaterials, The Second Affiliated Hospital of Jiaxing University, 1518 North Huancheng Road, Jiaxing 314000, P. R. China Enanta Pharmaceuticals Inc., Watertown, Massachusetts, USA Department of Heart Disease, Yantai Hospital of Traditional Chinese Medicine, Yantai, Shandong, China State Key Laboratory of Urban Water Resource and Environment Harbin Institute of Technology Harbin 150090 P. R. China Department of Orthopedic Trauma Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai, China (mainland) Shanghai Key Lab of Chemical Assessment and Sustainability; Department of Chemistry; Tongji University; Shanghai; P. R. China Institute of Harbin Hematology & Oncology, The First Hospital of Harbin, Harbin, Heilongjiang, China aState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine,; eDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China. Department of Dermatology, Tri‐Service General Hospital National Defense Medical Center Taipei Taiwan Xijie Wang, Bin Dong, and Jun Ma are with the Institute of Child and Adolescent Health and the School of Public Health, Peking University, Beijing, China. Zhiqiang Wang is with the Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia. College of Life Sciences Fujian Agriculture and Forestry University Fuzhou 350002 China; Plant Synthetic Biology Center, FAFU‐UCR Joint Center for Horticultural Biology and Metabolomics, Haixia Institute of Science and Technology Fujian Agriculture and Forestry University Fuzhou 350002 China Department of Liver Transplantation Shanghai Changzheng Hospital 415 Fengyang Road 200003 Shanghai People’s Republic of China Department of Colorectal Surgery Changhai Hospital Second Military Medical University Shanghai 200433 China Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan Department of Orthopedic Trauma Surgery, Changzheng Hospital, The Second Military Medical University, Shanghai, China; Eye Institute Eye & ENT Hospital Shanghai Medical College Fudan University Shanghai 200031 China Department of Family Health Care Nursing, University of California, San Francisco, San Francisco, California (Dr Chesla, Dr Gay, Dr Hernandez); University of San Francisco, San Francisco, California (Dr Chun); Donaldina Cameron House, San Francisco, California (Ms Kwong); Department of Physiological Nursing, University of California, San Francisco, San Francisco, California (Dr Chi); Diabetes Teaching Center, University of California, San Francisco, San Francisco, California (Ms Huang) 1Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong, P. R. China. Medical Research Center, Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450014, China. [email protected]. Department of Herbology, College of Korean Medicine, Dongguk University, Gyeongju, Gyeongbuk 38066, Republic of Korea University of Cincinnati College of Medicine 1 Division of Developmental Biology, Children’s Hospital Research Foundation, and Graduate Program in Developmental Biology , , 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA Advanced Biomaterials and Tissue Engineering Center Huazhong University of Science and Technology Wuhan 430074 China; Department of Biomedical Engineering Huazhong University of Science and Technology Wuhan 430074 China Shenzhen Wanhe Pharmaceutical Company & Guangdong Provincial Key Laboratory of Microecological Preparations, 7 Huitong Road, Shenzhen 518107, China Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Chengdu - China GeneNews Limited, Richmond Hill, Ontario, Canada; Department of Anesthesiology, Beijing Anzhen Hospital Capital Medical University‐Beijing Institute of Heart Lung and Blood Vessel Diseases Beijing People's Republic of China Chemical Engineering Research Center Tianjin Key Laboratory of Membrane Science and Desalination Technology Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) State Key Laboratory of Chemical Engineering (Tianjin University) School of Chemical Engineering and Technology Tianjin University Tianjin 300350 P. R. China; Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192 P. R. China Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, 415 Fengyang Road, Shanghai, 200003, China State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, China Department of Herbology, College of Korean Medicine, Dongguk University, Gyeongju, North Gyeongsang 38066, Republic of Korea Crop Ecophysiology and Cultivation Key Laboratory of Sichuan Province, Rice Research Institute, Sichuan Agricultural University, Chengdu 611130, China Department of Dermatology, University of Pennsylvania, PA 19104, USA.; Department of Biology, University of Pennsylvania, PA 19104, USA. Department of Molecular , Cellular, and Developmental Biology and Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109-2216 From the Department of Clinical Oncology, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR; and Department of Radiation Oncology & Department of Nasopharyngeal Carcinoma, Cancer Center, Sun Yat-sen University, Guangzhou, China Department of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA School of Public Health, Wannan Medical College, Wuhu, Anhui, China (mainland) Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering South China University of Technology Guangzhou 510640 China Department of Postgraduate Students, Hubei College of TCM, Wuhan 430061, China. [email protected] Department of General Surgery Minhang Hospital Fudan University Shanghai China Peking University Tianjin Medical University General Hospital Tianjin China State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, and Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Sun Yat‐Sen University Cancer Center Guangzhou China School of Engineering, University of South Australia, SA5095, Australia Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People’s Republic of China Thoracic Surgery Department, 1st Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, Guangdong, China Division of Biomedical Informatics Cincinnati Children's Research Foundation Cincinnati OH USA; Division of Developmental Biology Cincinnati Children's Research Foundation Cincinnati OH USA Department of Neurobiology, School of Life Sciences, China Medical University, Shenyang, China; Key Laboratory of Cell Biology, Ministry of Public Health of China, China Medical University, Shenyang, China; Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang, China Radiotherapy Department, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, P. R. China Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China Qingdao Industrial Energy Storage Research Institute, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, P. R. China; Shandong Energy Institute, Qingdao 266101, P. R. China Department of OrthopedicsChangzheng HospitalSecond Military Medical UniversityShanghaiPeople's Republic of China Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science, National Synchrotron Radiation Laboratory, School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui 230026, China Department of Chemical Engineering, School of Chemistry and Chemical Engineering, Guizhou University, Guiyang, Guizhou 550025, China; Guizhou Key Laboratory for Green Chemical and Clean Energy Technology, Guiyang, Guizhou 550025, China Institute of Naval Medical Research From the Palo Alto Medical Foundation Research Institute (J.M.), Palo Alto, Calif; and the Program on Prevention Outcomes and Practices (R.S.S.), Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, Calif. Institute of Quality Standard and Testing Technology for Agro-Products, Key Laboratory of Agro-Product Quality and Safety, Chinese Academy of Agricultural Sciences; Key Laboratory of Agro-Product Quality and Safety, Ministry of Agriculture, Beijing 100081, P.R. China School of Chemical Science and Engineering, Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, China School of Environment, Harbin Institute of Technology, Harbin 150009, China. Department of Burns, Nanfang Hospital Southern Medical University Guangzhou Guangdong Province China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, 651 Dongfeng Road East, Guangzhou 510060, People’s Republic of China Palo Alto Medical Foundation Research Institute, Palo Alto, California; Department of Medicine, Stanford University School of Medicine, Stanford, California The First Clinical Medical School of Shanxi Medical University, Taiyuan, Shanxi 030001, P.R. China Department of Orthopedics, Affiliated Suqian Hospital of Xuzhou Medical College, Suqian, Jiangsu, China Cancer Center, Sun Yat-sen University, Guangzhou 510060, P. R. China. [email protected] Epidemiology and Biostatistics Institute School of Public Health Tianjin Medical University Tianjin People’s Republic of China Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China (mainland) Clinic and Research Center of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China; Department of Tuberculosis, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200092, China College of Landscape Architecture of Sichuan Agricultural University, Chengdu, Sichuan, China. Department of Chemistry and Biochemistry, University of Wisconsin—Milwaukee, 3210 North Cramer, Milwaukee, Wisconsin 53211 Department of Hepatobiliary and Pancreatic Surgery The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital Kunming China Key Laboratory of Functional Molecular Engineering of Guangdong Province; School of Chemistry and Chemical Engineering; South China University of Technology; Guangzhou; P. R. China Department of Obstetrics and Gynecology Shanghai Key Laboratory of Gynecologic Oncology Renji Hospital School of Medicine Shanghai Jiaotong University Shanghai 200127 P. R. China Hebei Medical University-National University of Ireland Galway Stem Cell Research Center, Hebei Medical University, Hebei Province 050017, China; Hebei Research Center for Stem Cell Medical Translational Engineering, Hebei Province 050017, China; Human Anatomy Department, Hebei Medical University, Hebei Province 050017, China Department of Obstetrics and Gynecology Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai China Department of Chemistry; Capital Normal University; Beijing 100048; P. R. China 1 Division of Biomedical Informatics, 2Division of Developmental Biology, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA and 3Key Laboratory of Cell Proliferation and Differentiation, Center of Developmental Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871, P.R. China; 1 Division of Biomedical Informatics, 2Division of Developmental Biology, Cincinnati Children's Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA and 3Key Laboratory of Cell Proliferation and Differentiation, Center of Developmental Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871, P.R. China Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, People’s Republic of China State Key Laboratory of Urban Water Resource and Environment, and School of Municipal and Environmental Engineering, Harbin Institute of Technology, 73, Huanghe Rd, Nangang Dist., Harbin 150090, China Department of Dermatology, Shanghai Skin Disease Hospital, Shanghai, P. R. China College of Landscape Architecture, Sichuan Agricultural University, Wenjiang, Sichuan, P. R. China; College of Landscape Architecture, Sichuan Agricultural University, Chengdu 611130, China Department of Veterinary Surgery, College of Veterinary Medicine Northeast Agricultural University Harbin People's Republic of China; Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, College of Veterinary Medicine Northeast Agricultural University Harbin People's Republic of China National Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China Department of Orthopaedics, Changzheng HospitalSecond Military Medical UniversityShanghaiPeople's Republic of China Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan; Department of Psychiatry, Wuhan Mental Health Center; Wuhan Hospital for Psychotherapy, Wuhan, China U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Regulatory Science, 5100 Paint Branch Pkwy, College Park, MD 20740 Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA. School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China Department of Mechanical Science and Engineering, ‡Department of Electrical and Computer Engineering, and §Micro and Nanotechnology Laboratory, University of Ilinois at Urbana−Champaign, Urbana Illinois 61801, United States Bioinformatics Research Center, North Carolina State University, Durham, NC, USA; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, USA Department of Hematology & Oncology, Harbin Institute of Hematology & Oncology Harbin 150010, Heilongjiang, China. CAD & Knowledge Solutions, Siemens Healthcare, Malvern, PA 19355, USA. Beijing University Health Science Center, 38 Xue Yuan Road, Beijing 100191, China State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, PR China;; National Engineering Research Center of Urban Water Resource and Environment, Harbin 150090, PR China. Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People's Republic of China Department of Chemistry & Biochemistry, University of WisconsinMilwaukee, Milwaukee, Wisconsin 53201 Institute of Harbin Hematology & Oncology, Harbin First Hospital, Harbin 150010, Heilongjiang Province, China . E-mail: [email protected]. From the Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China (Y.D., J.M., Y.S., Y.M., B.D., Z.Z.) South China Agricultural University, China; Sichuan Agricultural University, China From the Stanford Prevention Research Center, Stanford University School of Medicine, Stanford, Calif. Guangdong Institute for Drug Control, Guangzhou, China Shanghai Center for Plant Stress Biology, Chinese Academy of Sciences, Shanghai, China State Key Laboratory of Animal Biotech Breeding and Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Biological Sciences, China Agricultural University, Beijing 100193, China 1National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, China. Biomedical Applications Group, Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, Pennsylvania;; Joint Carnegie Mellon-University of Pittsburgh PhD Program in Computational Biology, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania; National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University (SCAU), Guangzhou, China. Clinic and Research Centre of Tuberculosis, Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University, Shanghai, People’s Republic of China Griffith Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia Department of Hematology & Oncology, Harbin Institute of Hematology and Oncology, Harbin, Heilongjiang 150010, China. Department of Nephrology, Jing An District Center Hospital of Shanghai, Shanghai, China Department of Radiation Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou People's Republic of China Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Institute of Biodiversity Science, Fudan University, Shanghai 200433, China. |
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