http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_ad3f5c44d079dc3fd68fddd22eaec078
Outgoing Links
| Predicate | Object |
|---|---|
| family-name | Chen Qian Chen |
| name | Qian Chen |
| given-name | Qian |
| organization-name | Departments of †Materials Science and Engineering, ‡Chemistry, and §Physics, University of Illinois, Urbana, Illinois 61801, United States Department of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School Nanjing University Nanjing China; Medical Imaging Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School Nanjing University Nanjing China; Institute of Medical Imaging and Artificial Intelligence Nanjing University Nanjing China Department of Plastic and Aesthetic Surgery Nanfang Hospital of Southern Medical University Guangzhou Guangdong China Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China Department of Physics, Southeast University, Nanjing 211189, People’s Republic of China Department of Neurology, The affiliated hospital of Capital Institute of Pediatrics , Beijing 100020 , China School of Environmental Science and Engineering, Zhejiang Gongshang University, Hangzhou 310012, China Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai 200092, China. Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University; Key NHC Key Laboratory of Myopia Fudan University; Laboratory of Myopia, Chinese Academy of Medical Sciences Laboratory Center The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou China School of Chemistry and Life Science; Changchun University of Technology; Changchun 130012; P. R. China Department of Pathology, The Third Xiangya Hospital, The Central South University Changsha, Hunan, China. Beijing Center for Disease Control and Prevention, Beijing, People's Republic of China. Andover Innovative Medicines Institute, Eisai Inc., Andover, MA, USA Institute of Functional Nano and Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐based Functional Materials and Devices Soochow University Suzhou Jiangsu 215123 China Department of Chemistry Southern University of Science and Technology Shenzhen Guangdong 518055 China Thorgene Co., Ltd., Beijing, 100176, China Department of Physics, Southeast University, Nanjing 211189, China Department of Obstetrics and Gynecology, Peking University, First Hospital , Beijing , P.R. China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fujian Fuzhou 350002 P. R. China State Key Laboratory of Animal Biotech Breeding, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China Department of Anesthesiology, the Affiliated Jiangning Hospital of Nanjing Medical University, Nangjing, China Department of Orthopaedic Surgery, Zhongshan Hospital Fudan University Shanghai China Department of Otolaryngology, Guangzhou Children's Hospital, Guangzhou, 510120, China. [email protected] Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China Department of Physiology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; Harold Hamm Diabetes Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Department of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, International Business Incubator, Guangzhou Science Park, Guangzhou 510663, P. R. China Cell and Molecular Biology LaboratoryDepartment of OrthopaedicsAlpert Medical School of Brown University/Rhode Island HospitalProvidenceRhode IslandUSA School of Chemistry and Chemical Engineering; Jiangsu University; Zhenjiang; P. R. China School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma’anshan, Anhui 243032, China Institute of Plant Nutrition, Resources and Environment, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China Institute of Functional Nano and Soft Materials (FUNSOM); Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices; Soochow University; Suzhou 215123; China [email protected] Institute of New Type Optoelectronic Materials and Technology, College of Big Data and Information Engineering, Guizhou University, Guiyang 550025, China; State Key Laboratory of Public Big Data, Guizhou University, Guiyang 550025, China National Laboratory of Applied Organic Chemistry and State Key Laboratory of Arid Agroecology, Lanzhou University, Gansu 730000, PRC State Key Laboratory for Modification of Chemical Fibers and Polymer Materials; College of Materials Science and Engineering; Donghua University; Shanghai 201620 P. R. China College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, People’s Republic of China Applied Engineering Technology Research Center for Functional Membranes, Institute of Advanced Technology, University of Science and Technology of China, Hefei 230088, China; Anhui Provincial Engineering Laboratory of Functional Membrane Materials and Technology, Department of Applied Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026, China Department of Grassland Science, China Agricultural University, Beijing, China Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan and The Academy of Fundamental and Interdisciplinary Science, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, P. R. China Department of Gynaecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China Wuhan National Laboratory for Optoelectronics and School of Optical and Electronic Information Huazhong University of Science and Technology Wuhan 430074 Hubei P.R. China College of Chemistry & Chemical Engineering, Inner Mongolia University, Hohhot 010021, PR China Department of Endocrinology, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400000, China Key Laboratory of Myopia, Ministry of Health, Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, 215123, P. R. China State Key Laboratory of Electronic Thin Films and Integrated Devices; School of Optoelectronic Science and Engineering; University of Electronic Science and Technology of China; Chengdu 610054; P. R. China Analytical & Testing Center, State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu, 610064, China CAS Key Laboratory for Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen China; University of Chinese Academy of Sciences Beijing China State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Med-X Center for Materials, Sichuan University, Chengdu, China School of Electronic and Optical Engineering, Nanjing University of Science & Technology, 200 Xiaolingwei, Nanjing 210094, China; The Jiangsu Key Laboratory of Spectral Imaging & Intelligent Sense, Nanjing 210094, China Central and Clinical Laboratory of Sanya People’s Hospital, Sanya, Hainan572000, People’s Republic of China West China Hospital/West China School of Nursing, Sichuan University Chengdu, Sichuan, No. 37, Guoxue Alley, Chengdu, Sichuan Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, P. R. China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, Guangdong Province, P. R. China Zhejiang Center for Clinical Laboratories Zhejiang Provincial People's Hospital Hangzhou China Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China; Key NHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China; Key NHC Key Laboratory of Myopia (Fudan University), Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China School of Materials Science and Engineering Ocean University of China 1299 Sansha Road Qingdao Shandong Province 266100 P. R. China Molecular Mechanism of Disease & Research and Development of Bioactive Substances, College of Life Science & Technology Heilongjiang Bayi Agricultura University Daqing China Key Laboratory of Ministry of Education on Traditional Chinese Medicine Resource and Compound Prescription & Hubei University of Chinese Medicine, Wuhan 430065, China. [email protected] Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, Guangdong, China State Key Laboratory of Pharmaceutical Biotechnology Medical School and School of Life Sciences Nanjing University Nanjing 210093 China Department of Nuclear Medicine, Beijing Tiantan Hospital Capital Medical University Beijing China CNS Astellas Research Institute of America LLC Skokie IL USA State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, Guizhou 550004, People’s Republic of China Key Laboratory of Bio-Resources and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University , Chengdu , China Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence Rhode Island Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, and International Cancer Center, Shenzhen University School of Medicine, Shenzhen 518055, China; Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen 518055, China; Health Science Centre School of Basic Medical Sciences, Shenzhen University, Shenzhen 518055, China McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China The Second Affiliated Hospital of Kunming Medical University Kunming China State Key Laboratory of Environment‐Friendly Energy Materials School of Materials and Chemistry Southwest University of Science and Technology Mianyang 621010 P. R. China Department of Ophthalmology Eye & ENT Hospital of Shanghai Medical School, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University Shanghai 200031 China Liver Unit, Internal Medicine Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) del Instituto de Salud Carlos III, Madrid, Spain Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China Molecular Mechanism of Disease and Research and Development of Bioactive Substances, College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, Heilongjiang Province, P.R. China Department of Nutrition, School of Public Health, Sun Yat-Sen University (North Campus), Guangzhou 510080, PR China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou 510080, PR China Northern Blood Research Centre, Kolling Institution of Medical Research, The University of Sydney, St Leonards, Australia; College of Computer Science and Technology in the Jilin University State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design Chinese Academy of Sciences Beijing China Department of Medicinal Chemistry; School of Pharmacy; Chongqing Medical University; Chongqing 400016; P. R. China Central Research Institute, Shanghai Pharmaceutical Holding Co., Ltd., Building 5, 898 Ha Lei Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China; University of Chinese Academy of Sciences Beijing 100049 China School of Chemistry & Chemical Engineering, Henan University of Technology, Zhengzhou 450001, China Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, U.S.A.; Eye Institute of Xiamen University, Xiamen City, Fujian Province, China School of Electrical and Information Engineering, Jiangsu University, Zhenjiang 212013, China Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China Eisai Research Institute, Wilmington, Massachusetts 01887 School of Chemistry & Chemical Engineering; Henan University of Technology; Academician Workstation for Natural Medicinal Chemistry of Henan Province; Zhengzhou 450001; China Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China Shanghai Istitute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P. R. China Tufts University Health Sciences Schools, 136 Harrison Ave, Boston, MA 02111, USA 1 Department of Anatomy and Cellular Biology , Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China Department of Materials Science and Engineering and Department of Chemistry, University of Illinois at Urbana−Champaign, Urbana, Illinois 61801 College of Food Science, Northeast Agricultural University, Harbin 150030, China aLaboratory of Molecular Immunoregulation, Division of Basic Sciences, State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Orthopaedics, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, USA; Bone and Joint Research Center, the First Affiliated Hospital of Medical School, Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, Shaanxi, China Laboratory of Human Retrovirology and Immunoinformatics, Applied and Development Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA. Institute of Plant Virology, Fujian Agriculture and Forest University, Fuzhou 350002,Peopleʼs Republic of China Department of Clinical Oncology Renmin Hospital of Wuhan University Wuhan Hubei China State Key Laboratory of Photocatalysis on Energy and Environment College of Chemistry Fuzhou University 350108 Fuzhou P. R. China Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, P.R. China Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Soochow University Suzhou 215123 China Department of Orthopaedic Surgery; Zhongshan Hospital; Fudan University; Shanghai 200032; China Department of Oncology, The Affiliated Suzhou Hospital of Nanjing Medical University, 242 Guangji Road, Suzhou 215008, Jiangsu, China Viral Hepatitis Laboratory, Liver Unit-Internal Medicine, Vall d'Hebron Research Institute (VHIR), Hospital Universitari Vall d'Hebron (HUVH), Barcelona, Spain The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070, China State Key Laboratory of Agro‐biotechnology College of Biological Sciences China Agricultural University Beijing People's Republic of China State Key Laboratory of Functions and Applications of Medicinal Plants and School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang 550004, People’s Republic of China School of Public Health, Xuzhou Medical University Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, China Department of Geriatric Cardiology, Chinese People’s Liberation Army (PLA) General Hospital & Medical School of Chinese PLA, Beijing, China College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China; College of Food Science, Northeast Agricultural University, Harbin 150030, China College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China. State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of Life Science, Nanjing University, Nanjing 210093, China College of Life and Environmental Science, Wenzhou University, Wenzhou 325035, China State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Nanchang University, Nanchang 330047, China Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing 100081, China Shenzhen Laboratory of Fully Human Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, University City of Shenzhen, Xili Nanshan, Shenzhen, 518055, P.R. China; University of Chinese Academy of Sciences, Beijing, 100049, P.R. China Institute of Medical Technology, Peking University Health Science Center, Beijing, China Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College Chinese Academy of Medical Sciences Beijing China From the Center for Genetics and Developmental Systems Biology, Department of Obstetrics and Gynecology, Nanfang Hospital (Xiaoxue Yang, J.Y., X.L., Q.C., S.J., H.L., Y.G., Z.R., Y.Y., M.Z., Xinping Yang), Southern Medical University, Guangzhou, Guangdong, China Endoscopic Unit, Department of Gastroenterology and Hepatology at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China Department of Cardio‐Thoracic Surgery Second Xiangya Hospital of Central South University Changsha China School of Chemical Engineering and Light Industry, Guangdong University of Technology Department of Ophthalmology, Xiang'an Hospital of Xiamen University; Fujian Provincial Key Laboratory of Ophthalmology and Visual Science; Eye Institute of Xiamen University; School of Medicine, Xiamen University, Xiamen, Fujian, China; Xiamen University affiliated Xiamen Eye Center, Xiamen, Fujian, China Department of Ophthalmology and Visual Science Eye, Ear, Nose and Throat Hospital Fudan University Shanghai People's Republic of China; Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai Shanghai People's Republic of China; Key Laboratory of Myopia Chinese Academy of Medical Sciences NHC Key Laboratory of Myopia (Fudan University) Shanghai People's Republic of China Department of Obstetrics and Gynecology, West China Second Hospital, Sichuan University, Chengdu 610041, China. Department of Pediatric Neurosurgery Shenzhen Children's Hospital Shenzhen China College of Acupuncture-moxibustion and Orthopedics, Hubei Provincial Collaborative Innovation Center for Preventive Treatment of Diseases with Acupuncture and Moxibustion, Hubei University of Chinese Medicine, Wuhan 430061, China. Department of Respiratory Medicine, People’s Hospital of Ningxia Hui Autonomous Region, Yinchuan 750000, Ningxia, China; Department of Respiratory Medicine, Third Clinical Medical College, Ningxia Medical University, Yinchuan 750000, Ningxia, China State Key Laboratory of Food Science and Technology; Nanchang University; Nanchang 330047; Peoplés Republic of China State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing 100193, China Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China Molecular Mechanism of Disease & Research and Development of Bioactive Substances, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, 163319 Heilongjiang Province, China Institute of Functional Nano & Soft Materials (FUNSOM) Collaborative Innovation Center of Suzhou Nano Science & Technology Soochow University Suzhou Jiangsu 215123 China School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116, China Institute of Pathogenic Biology, Medical College, University of South China, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control and Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Hengyang 4 2Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702 Department of Chemistry University of Illinois at Urbana‐Champaign 600 S. Mathews Avenue Urbana IL 61801 USA; Department of Chemical and Biomolecular Engineering University of Illinois at Urbana‐Champaign 600 S. Mathews Avenue Urbana IL 61801 USA; Department of Materials Science and Engineering University of Illinois at Urbana‐Champaign 1304 W. Green Street Urbana IL 61801 USA; Materials Research Laboratory University of Illinois at Urbana‐Champaign 104 South Goodwin Avenue, MC‐230 Urbana IL 61801 USA; Beckman Institute for Advanced Science and Technology University of Illinois at Urbana‐Champaign 405 N. Mathews Avenue Urbana IL 61801 USA College of Agronomy, Shenyang Agricultural University, Shenyang, Liaoning, China Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China State Key Laboratory of Bioreactor Engineering; East China University of Science and Technology; Shanghai; China Department of General Surgery, Southwest Hospital, Military Medical University, Chongqing 400038, China. School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma Xiang Road, Ma’anshan, Anhui 243032, P. R. China Department of Gastroenterology and Hepatology , Tongji Hospital, Tongji Medical College, HUST , 1095 Jiefang Ave , Wuhan 430030 , China Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. [email protected]. State Key Lab of Urban Water Resource and Environment (SKLUWRE) School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin Heilongjiang 150080 China Laboratory of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, People's Republic of China Musculoskeletal Research Laboratory, Department of Orthopaedics and Rehabilitation, and; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033; and Institute of Digestive Diseases LongHua Hospital Shanghai University of Traditional Chinese Medicine Shanghai 200032 China Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903 School of Statistics, Renmin University of China, Beijing 100872, China. [email protected] 1State Key Laboratory of Agrobiotechnology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China Department of Plant Pathology, University of California, Davis, California, USA; Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, People’s Republic of China Department of Obstetrics and Gynecology Nanfang Hospital Southern Medical University Guangzhou Guangdong PR China Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois Thorgene Co., Ltd., Yizhuang Biomedical Park, Daxing District, Beijing, Beijing, China The Sichuan Key Laboratory for Conservation Biology of Endangered Wildlife, Sichuan University, Chengdu 610064, China Department of Rehabilitation Medicine Nanjing Qixia District Hospital Nanjing China Institute for Solid State Physics, The University of Tokyo, Kashiwa, 277-8581, Japan Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health, Shanghai Jiao Tong University School of Medicine, Xinhua Hospital , Shanghai , China Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou 510080, China Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Soochow University Suzhou 215123 China Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China; Department of Orthopaedics, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, P.R. China Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, China Department of Gynecology and Obstetrics, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China Qian Chen is an associate professor at the Institute of Military Health Management, Second Military Medical University. Department of General Surgery, Minhang Hospital, Fudan University, Shanghai, People's Republic of China Department of Pathology, Third Xiangya Hospital, Central South University, Changsha 410013. Guizhou University College of Agriculture/College of Tobacco, Guizhou Provincial Key Laboratory of Tobacco Quality Research , Guiyang 550025 , China Department of Gynaecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, P. R. China Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China Key Laboratory of Water and Sediment Sciences, Ministry of Education, College of Environmental Sciences and Engineering, Peking University , 100871 Beijing, China; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University , 810016 Xining, China Department of Clinical Laboratory Medicine, Institution of Microbiology and Infectious Diseases, The First Affiliated Hospital, Hengyang Medical School University of South China Hengyang China State Key Laboratory of Plant Genomics, National Centre for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; Chinese-German Joint Group for Plant Hormone Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; Graduate School of Chinese Academy of Sciences, Beijing, 100039, China Thorgene Co., Ltd Beijing 100176 China College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China Department of Oncology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, PR China. Medical College of China Three Gorges University, Yichang 443002, China. Applied and Developmental Directorate 1 and 2; Advanced Technology Program Directorate, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702 1 and 2 Department of Pharmacy, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China National Clinical Research Centre for Geriatric Disorders, Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, Hunan, China Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, China. Central Laboratory Shanghai Xuhui Central Hospital Shanghai China Electronic and Biological Nanostructures Laboratory, College of Engineering, Michigan State University, East Lansing, MI 48824, USA. Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China. Sichuan Key Laboratory of Nursing, Chengdu 610041, China. Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, P. R. China 1Clinical Medicine Research Center, Xinqiao Hospital, Third Military Medical University, Chongqing, China. Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, People’s Republic of China Department of Pediatrics, Shandong Provincial Maternal and Child Health Care Hospital, No 238, Jingshi Eastern Road, Jinan 250014, Shandong Province, China Department of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, China; Division of HIFU Therapy, Hangzhou Integrative Medicine Hospital, Zhejiang, China Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs School of Life Science and Engineering Southwest Jiaotong University Chengdu P. R. China Department of Anesthesiology, East Hospital of Sichuan Provincial People's Hospital Department of Hematology The First People`s Hospital of Hefei Hefei China 3Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland. ‡Laboratory of Molecular Immunoregulation, Center for Cancer Research, and School of Chemistry & Chemical Engineering; Yangzhou University; Yangzhou; China State Key Laboratory of Plant Genomics, National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, No. 1 West Beichen Road, Beijing, 100101, P. R. China. Graduate University of Chinese Academy of Sciences, Beijing, 100049, P. R. China. State Key Laboratory of Pharmaceutical Biotechnology, Medical School & School of Life Sciences, Nanjing University, Nanjing, 210093, China; Institute of Drug R&D, Nanjing University, Nanjing, 210093, China Division of Infection and Immunity, Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, United Kingdom. Institute of Pediatrics, Nanjing Children's Hospital, Nanjing Medical University, Nanjing 210008, China. Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China Australian Key Centre for Microscopy and Microanalysis, The University of Sydney, NSW 2006, Australia, Department of Physics, Soochow University, Suzhou 215006, People’s Republic of China, National Laboratory of Solid State Microstructures and Department of Physics, Nanjing University, Nanjing 210093, People’s Republic of China, Department of Physics, Southeast University, Nanjing 211189, People’s Republic of China, and Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin,... Department of Nutrition School of Public Health Sun Yat‐sen University Guangzhou PR China; Guangdong Provincial Key Laboratory of Food Nutrition and Health Guangzhou PR China; Department of Cardiology Sun Yat‐sen Memorial Hospital Guangzhou PR China Reproductive Medical Center, Ruijin Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China Department of Materials Science and Engineering, University of Illinois, Urbana, IL 61801, USA. *Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and College of Medicine, China Three Gorges University, Yichang, China; Third-Grade Pharmacological Laboratory on Traditional Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, China Three Gorges University, Yichang China; The Second People’s Hospital of Yichang, China Three Gorges University, Yichang China Shandong University of Traditional Chinese Medicine, Jinan 250355, China; Shandong Co-Innovation Center of Classic TCM Formula, Jinan 250355, China From the Department of Ophthalmology (C.F., Q.C., X.S., G.T.), Eye and ENT Hospital, Fudan University; Department of Neurology (W.C., J.T.), Deji Hospital; and State Key Laboratory of Medical Neurobiology (X.S., G.T.), Institutes of Brain Science, Fudan University, Shanghai, China. School of Medicine, Tsinghua University, Beijing 100084, China Department of Human Anatomy, Histology and Embryology, Shanghai Key Laboratory for Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Center of Reproductive Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China Clinical Medicine Research Center, Xinqiao Hospital, Army Medical UniversityThird Military Medical University, Chongqing, China Department of Pediatric Neurosurgery, Shenzhen Children’s Hospital, Shenzhen, Guangdong, China Department of General Surgery; Minhang Hospital; Fudan University; Shanghai 201199; China State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guiyang, Guizhou, China; Department of General Surgery, Institute of Fudan-Minhang Academic Health System, Minhang Hospital, Shanghai, China Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering Northwestern Polytechnical University 127 West Youyi Road Xi'an 710072 P. R. China 1Department of Histo-Embryology, Genetics and Developmental Biology, Shanghai Jiaotong University, School of Medicine, Shanghai Key Laboratory of Reproductive Medicine, Huangpu, Shanghai, China; 2Center of Reproductive Medicine, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Huangpu, Shanghai, China Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China Department of Ophthalmology Shanghai General Hospital (Shanghai First People's Hospital) School of Medicine Shanghai Jiao Tong University Shanghai China College of Animal Science and Technology, Nanjing Agricultural University Nanjing China Department of Gastroenterology Shaanxi Provincial People's Hospital Xi'an China The Third Xiangya Hospital; Central South University; Changsha; PR China Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, 100853, China Departments of Medicine, and Key Laboratory of Irradiation Preservation of Sichuan Province Sichuan Institute of Atomic Energy Sichuan Chengdu China Department of Obstetrics and Gynecology, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Anhui Key Laboratory of Bioactivity of Natural Products, School of Pharmacy, Anhui Medical University, 81 Meishan Road, Hefei,China Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science and Technology, the Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu 215123, China Aier Eye Hospital of Wuhan University, Wuhan 430000, Hubei Province, China. Hankou Aier Eye Hospital, Wuhan 430000, Hubei Province, China. CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of Microbiology Chinese Academy of Sciences Beijing China; Institute of Physical Science and Information Anhui University Hefei China School of Physics; Southeast University; Nanjing 211189; China Anhui Provincial Engineering Laboratory of Functional Membrane Materials and Technology, Department of Applied Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026, China Department of Plastic and Aesthetic Surgery NanFang Hospital of Southern Medical University Guangzhou 510515 China All authors are affiliated with the Department of Dermatology, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute at Frederick, National Institutes of Health , Maryland Center of Comparative Medicine, University of California, Davis, California, USA State Key Laboratory of Medical Neurobiology Department of Ophthalmology Eye and ENT Hospital of Shanghai Medical School Institutes of Brain Science Fudan University Shanghai China Department of Plastic Surgery, Nanfang Hospital Southern Medical University Guangzhou China Translational Medical Center, Chinese People's Liberation Army General Hospital, Beijing, 100039, China Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States Zhejiang Provincial Key Laboratory for Genetic Improvement and Quality Control of Medical Plants, Hangzhou Normal University Hangzhou 310035, China Frontiers Science Center for Flexible Electronics, Xi’an Institute of Flexible Electronics (IFE) and Xi’an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an 710072, China State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmaceutical Sciences, Guizhou Medical University, 550004 Guiyang, China School of Physics, Southeast University; Nanjing; China Department of Bioengineering, University of California, Los Angeles, California 90095, United States; California NanoSystems Institute, Jonsson Comprehensive Cancer Center and Center for Minimally Invasive Therapeutics, University of California, Los Angeles, California 90095, United States; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, United States Department of Bioengineering California NanoSystems Institute Jonsson Comprehensive Cancer Center and Center for Minimally Invasive Therapeutics University of California Los Angeles CA 90095 USA; Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University Raleigh NC 27695 USA; Jiangsu Key Laboratory for Carbon‐Based Functional Materials and Devices Institute of Functional Nano and Soft Materials (FUNSOM) Soochow University 199 Ren'ai Road Suzhou 215123 Jiangsu P. R. China Department of Chemistry South University of Science and Technology of China Shenzhen P. R. China Department of Orthopedics, Affiliated Hospital of North Sichuan Medical College, Nanchong Sichuan, 637000, P.R.China. Department of Pathology, The Third Xiangya Hospital Central South University Changsha China Department of Oncology, Daping Hospital, Army Medical Center of People's Liberation Army (Chongqing Daping Hospital), Chongqing 400042, P.R. China Hematological Disease Institute of Jiangsu University, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China Central Laboratory Shanghai Xuhui Central Hospital/Zhongshan‐Xuhui Hospital Fudan University Shanghai 200031 China Department of Pediatric Neurosurgery Shenzhen Children Hospital Shenzhen China Fujian Province Key Laboratory of Plant Virology, Vector‐borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Fujian Agriculture and Forestry University Fuzhou Fujian China Department of Obstetrics and Gynecology Peking University First Hospital Beijing China Environment and Plant Protection Institute, Chinese Academy of Tropical Agriculture Sciences, Laboratory of Integrated Pest Management on Tropical Crops Ministry of Agriculture Haikou Hainan China; Hainan Key Laboratory for Monitoring and Control of Tropical Agricultural Pests Hainan Engineering Research Center for Biological Control of Tropical Crops Diseases and Insect Pests Haikou Hainan China 1Shenzhen Laboratory of Fully Human Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China. State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 P. R. China; Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Beijing 100049 P. R. China Institute of Neuroscience and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou, China; McGovern Institute for Brain Research at the Massachusetts Institute of Technology, Cambridge, Massachusetts. Molecular Science and Biomedicine Laboratory State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering College of Biology Aptamer Engineering Center of Hunan Province Hunan University Changsha Hunan 410082 China Department of Materials; University of Manchester; Manchester; UK Key Laboratory for Information System of Mountainous Area and Protection of Ecological Environment of Guizhou Province, Guizhou Normal University, Guiyang 550001, China. International Joint Research Centre for Aquatic Ecology, Guiyang 550001, China. Vector-borne Virus Research Center, Fujian Province Key Laboratory of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China Department of Plant Biotechnology and Bioinformatics Ghent University 9052 Ghent Belgium; VIB Center for Plant Systems Biology 9052 Ghent Belgium College of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Jinan PR China Department of Orthopaedics, Affiliated Hospital of North Sichuan Medical College, No. 63 Wenhua Road, Nanchong City, Sichuan Province 637000, P.R. China Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China Department of Urology Surgery, The Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning Province, China Department of Materials Science and Engineering, ‡Department of Physics, and §Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States College of Forestry, Agricultural University of Hebei, Baoding 071000, Hebei, China. Key Laboratory of Genetic Resources of Forest and Forest Protection of Hebei Province, Baoding 071000, Hebei, China. Department of Gastrointestinal Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine Wuhan 430061, Hubei Province, China. Hubei Province Academy of Traditional Chinese Medicine Wuhan 430074, Hubei Province, China. University Hospital Heidelberg, Heidelberg, Germany Department of Cardiovascular Medicine, The Third Affiliated Hospital, Sun Yat-sen University School of Clinical Medicine, Ningxia Medical University Yinchuan China; Department of Burns and Plastic Surgery Xinyang Central Hospital Xinyang China Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China Department of Oncology, The Affiliated Suzhou Hospital of Nanjing Medical University 242 Guangji Road, Suzhou 215008, Jiangsu, China. Central Laboratory, The Affiliated Suzhou Hospital of Nanjing Medical University 242 Guangji Road, Suzhou 215008, Jiangsu, China. Department of Geriatrics, West China Hospital and National Clinical Research Center for Geriatrics, Sichuan University, Chengdu, Sichuan Province, China. Department of Pharmacy, School of Pharmacy, Changzhou University, Changzhou, China Department of Anesthesiology, Southwest Hospital, Third Military Medical University, Chongqing, China; Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Chelsea and Westminster Campus, London, United Kingdom. PhD, RN, Professor, Center of Gerontology and Geriatrics, and National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Taiwan, ROC. State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, People’s Republic of China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Department of Respiratory Medicine Ningxia Hui Autonomous Region People's Hospital Yinchuan Ningxia China; Department of Respiratory Medicine The First Affiliated Hospital of Northwest University for Nationalities Yinchuan Ningxia China Department of Neonatology, Guangzhou Key Laboratory of Neonatal Intestinal Diseases The Third Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong People's Republic of China Department of Clinical Pharmacology, General Hospital of Peoples Liberation Army, Beijing 100853, China 6School of Mathematics and Statistics, Mathematical Institute, University of St. Andrews, St. Andrews, Fife, United Kingdom Analytical & Testing Center State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University Yihuan Rd Chengdu 610064 China Frontiers Science Center for Flexible Electronics; Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering; Northwestern Polytechnical University; Xi'an 710072; China Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry, Peking University, Beijing 100871, P. R. China Department of Environmental Engineering, Peking University; Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing 100871, China Nanjing Children's Hospital Affiliated to Nanjing Medical University, Nanjing, China. [email protected] State Key Laboratory of High-Performance Ceramics and Superfine Microstructure; Shanghai Institute of Ceramics; Chinese Academy of Sciences; Shanghai 200050; P. R. China Tongji University; Tongji University School of Medicine Department of Molecular & Medical Pharmacology, UCLA School of Medicine, Los Angeles, CA 90095, USA State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China Department of Orthopedics Alpert Medical School of Brown University/Rhode Island Hospital Providence RI USA Molecular Biology Laboratory, Department of Orthopaedics, Brown University, Providence, Rhode Island. Wuhan National Laboratory for Optoelectronics, School of Optical and Electronic Information Huazhong University of Science and Technology Wuhan 430074 Hubei China School of Chemistry & Chemical Engineering Yangzhou University Siwangting Road 180, Yangzhou Jiangsu 225002 China Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China. Department of Geriatrics, The West China Hospital of Sichuan University, Sichuan Province, China Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 100101 Beijing, China;; Institute of Physical Science and Information, Anhui University, 230039 Hefei, China; Department of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing 100071, China Clinical Research Center The First Affliated Hospital of Guizhou University of Traditional Chinese Medicine Guiyang Guizhou China Institute for Nutrition and Food Hygiene, Beijing Center for Disease Prevention and Control, Beijing, China Department of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China. College of Life Sciences, Northwest A&F University, Yangling 712100, Shaanxi, China. Shanghai Jiao Tong University *Laboratory of Molecular Immunoregulation, Division of Basic Sciences, and Department of Physics & Key Laboratory of MEMS of Ministry of Education; Southeast University; Nanjing, China Center for Evolution and Conservation Biology, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD; Second Affiliated Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, Shandong 271000, China Department of Materials Science and Engineering, ‡Department of Physics, and ⊥Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States; Department of Materials Science and Engineering and ∥Department of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, Illinois 60208, United States College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, P. R. China Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, Collaborative Innovation Center, West China Hospital, Sichuan University Chengdu, Sichuan Province, China. Department of Neurosurgery The Second Hospital of Hebei Medical University Shijiazhuang People’s Republic of China Oncology Department, Huanhu Hospital, Tianjin 300060, China. [email protected] College of Forestry, Northwest A&F University, Xianyang 712100, China From the Departments of Radiology (Z.F., H.L., H.Z., Y.J., Q.L., W.W., P.R.) and Pathology (Q.C.), The Third Xiangya Hospital of Central South University, No. 138 Tongzipo Road, Changsha 410013, China. State Key Laboratory of Crop Biology, College of Agronomy, Shandong Agricultural University, Taian, 271018 Shandong, China Shandong Provincial Key Laboratory of Oral Tissue Regeneration Shandong University Jinan Shandong China; Department of Periodontology School of Dentistry Shandong University State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China Research Institute of Wood Industry, Chinese Academy of Forestry, Beijing 100091, China State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China Department of Animal Breeding and Reproduction, College of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China; Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China Institute of Health Quarantine, Chinese Academy of Inspection and Quarantine, Beijing, P. R. China. Nanomedicine and Intestinal Microecology Research Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, China Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University) Chongqing PR China Institute of Plant Virology, Fujian Province Key Laboratory of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, People's Republic of China Second Clinical Division, Peking University School and Hospital of Stomatology, Beijing 100101, China. Department of Chemistry, Southern University of Science and Technology 2 , Shenzhen 518000, China Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200433, P. R. China Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. Central Laboratory Shanghai Xuhui Central Hospital/Zhongshan‐Xuhui Hospital Fudan University Shanghai China; Shanghai Engineering Research Center of Phase I Clinical Research and Quality Consistency Evaluation for Drugs Shanghai China School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, People’s Republic of China School of Mechanical and Power Engineering, Nanjing Tech University, Nanjing 211800, China Department of Physics, ‡Chien-Shiung Wu College, and §Key Laboratory of MEMS of Ministry of Education, Southeast University, Nanjing 211189, China College of Animal Science South China Agricultural University, National Engineering Research Center for Breeding Swine Industry and Guangdong Provincial Key Laboratory of Agro-Animal Genomics Guangzhou 510642 China Cell and Molecular Biology Laboratory, Department of Orthopaedics Alpert Medical School of Brown University/Rhode Island Hospital, Providence, Rhode Island, USA Centro de Biología Molecular “Severo Ochoa” (CBMSO, CSIC-UAM), Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain; Liver Unit, Internal Medicine Hospital Universitari Vall d’Hebron, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China Key Laboratory for Analytical Science of Food Safety and Biology of MOE, Fujian Provincial Key Lab of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, China Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐based Functional Materials and Devices Soochow University Suzhou Jiangsu 215123 China Department of Neurosurgery, Tianjin TEDA Hospital, Tianjin, China (mainland) Department of Biomedical Engineering Southern University of Science and Technology Shenzhen China New Industry Creation Hatchery Center Tohoku University 6‐6‐10 Aoba, Aramaki, Aoba‐ku Sendai 980‐8579 Japan; Institute for Materials Research Tohoku University 2‐1‐1 Katahira, Aoba‐ku Sendai 980‐8577 Japan Department of Obstetrics·and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, No. 20, Section 3, Renmin Nanlu, Chengdu, 610041, China Laboratory of Molecular Immunoregulation, Division of Basic Sciences , Frederick, Maryland Biomedical Analysis Center, Army Medical University, Third Military Medical University 3 , Chongqing 400038, China National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha China; Department of Oncology, Xiangya Hospital Central South University Changsha China Center for Biomedical Analysis College of Basic Medicine Army Medical University Chongqing 400038 China Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, People’s Republic of China. Department of Pathology, Third Xiangya Hospital, Central South University, Changsha 410013, China. [email protected] Frontiers Science Center for Flexible Electronics, Xi’an Institute of Flexible Electronics (IFE), and Xi’an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an 710072, China Fuzhou University College of Chemistry CHINA West China Hospital/West China School of Nursing Sichuan University Chengdu China The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, P.R. China Department of Gastroenterology and Hepatology Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST) Wuhan China McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts Vector-borne Virus Research Center, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China Department of Pediatric Neurology, Capital Institute of Pediatrics, Beijing 100020, China. Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University School of Medicine, Shanghai, China (mainland) Department of Orthopaedics, the Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan, China. State Key Laboratory for Manufacturing Systems Engineering; Xi'an Jiaotong University; Xi'an 710049, China Department of Oncology, Qilu Hospital of Shandong University, Jinan, Shandong 250112, P.R. China Medical Affair Department, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China Southern University of Science and Technology Chair of Methods for Model-based Development in Computational Engineering, RWTH Aachen University, Aachen, Germany. Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, P.R. China Guangxi Key Laboratory of Agric-Environment and Agric-Products Safety, Agricultural College of Guangxi University, Nanning 530004, China Department of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, China College of Life Science, Liaoning Normal University, Dalian, Liaoning 116029, P.R. China Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Soochow University Suzhou Jiangsu 215123 China Zhongshan Hospital of Fudan University, Shanghai 200032, China. Department of Physiology and Nanjing Univ. of Science and Technology Department of General Surgery, Shanghai Minhang Centre Hospital, Shanghai 201100, China Department of Environmental Engineering, Peking University, Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, People’s Republic of China Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China; Department of Plastic and Cosmetic Surgery, Hunan Provincial People’s Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China Laboratory Center, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu 215008, P.R. China Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐Based Functional Materials and Devices Soochow University Suzhou 215123 China State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-Xi Road, Shanghai 200050, China Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan School of Chemical Engineering and Light Industry Guangdong University of Technology Guangzhou China Beijing Centre for Disease Control and Prevention, Beijing 100013, China. Institute of Pharmaceutics, Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China Department of Radiology, Affiliated Jinling Hospital (Q.C., C.X.T., L.Y., P.X., L.J.Z.), Nanjing Medical University, China.; Department of Radiology, Nanjing First Hospital (Q.C., G.X., Y.F., Y.H., S.Z., H.X., X.Y.), Nanjing Medical University, China. Departments of Medicine and Surgery, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903; and School of Chemical Engineering and Light Industry Guangdong University of Technology Guangzhou 510006 P.R. China Department of Ocular Immunology, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China Department of Materials Science and Engineering, University of Illinois at Urbana−Champaign, 104 South Goodwin Ave, Urbana, Illinois 61801, United States Institute of Cellular and Molecular Biology and Department of Molecular, Cellular, and Developmental Biology, University of Texas at Austin, Austin, TX 78712 School of Automobile and Traffic Engineering, Hefei University of Technology, Hefei, Anhui, P. R. China Key Laboratory of Aquatic Product Processing, Ministry of Agriculture and Rural Affairs of The People's Republic of China, National R&D Center for Aquatic Product Processing, South China Fisheries Research Institute Chinese Academy of Fishery Sciences Guangzhou China Department of Materials Science and Engineering and the Frederick Seitz Materials Research Laboratory, ‡Department of Physics, and §Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650092. Nanjing University of Science and Technology 3Center for Comparative Medicine, University of California, Davis, California. From the Department of Physiology, the Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan. Beijing Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850. Department of Neurology, Capital Institute of Pediatrics, Beijing 100020, China Department of Molecular Cellular and Developmental Biology 1 and 2; Departments of Molecular Biophysics and Biochemistry and of Cell Biology, Yale University, New Haven, CT 06520 1 and 2 Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States, and Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853, United States Department of Pharmaceutics, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China Wuhan National Laboratory for Optoelectronics School of Optical and Electronic Information Huazhong University of Science and Technology Wuhan 430074 Hubei China School of Materials Science and Engineering Beihang University Beijing 100191 China Institute of Pathogenic Biology, Medical College, University of South China, Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study Hengyang China College of Food Science; Northeast Agricultural University; Harbin; China Guangdong Technology Research Center for Marine Algal Bioengineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China; Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China; Shenzhen Engineering Laboratory for Marine Algal Biotechnology, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China; Shenzhen Key Laboratory of Marine Bioresources and Ecology, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China Thorgene Co., Ltd. Beijing China Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China; National Clinical Research Center for Obstetrical and Gynecological Diseases, Wuhan, Hubei 430030, China; Key Laboratory of Cancer Invasion and Metastasis, Ministry of Education, Wuhan, Hubei 430030, China Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, CA 91010 School of Chemistry and Chemical Engineering, School of Medicine, School of the Environment and Safety Engineering, Key Laboratory of Modern Agriculture Equipment and Technology, Jiangsu University, Zhenjiang, Jiangsu 212013, P. R. China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Vector‐borne Virus Research Center Fujian Agriculture and Forestry University Fuzhou China College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, People’s Republic of China Institute of Basic Medical sciences, Academey of Military Medical Sciences, Beijing 100850, China. School of Life and Environmental Sciences, Wenzhou University, Wenzhou, China; and College of Forestry, Fujian Agriculture and Forestry University, Fuzhou, PR China Guangxi University Key Lab of Complex System Optimization and Big Data Processing, Guangxi Applied Mathematics Center, Yulin Normal University, Yulin 537000, China Department of Chemistry; University of California; Berkeley, USA; Materials Sciences Division; Lawrence Berkeley National Laboratory State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang 550004, People's Republic of China Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign , Urbana, IL , United States Graduate School of Tianjin Medical University Tianjin China School of Public Health, Dali University, Dali, China Department of Reproductive Medicine, The First Affiliated Hospital of Xian Jiaotong University, Xi'an 710061, China. School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma Xiang Road, Ma ‘anshan, Anhui 243032, PR China Shanghai Institute of Transplantation Department of Liver Surgery Institute of Molecular Medicine Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200127 P. R. China Department of Biochemistry and Molecular Biology, School of Basic Medical Science, Xi’an Jiaotong University Health Science Center, Xi’an, Shaan Xi 710061, China; Key Laboratory of Environment and Genes Related to Diseases, Xi’an Jiaotong University, Ministry of Education of China, Xi’an, Shaan Xi 710061, China Key Laboratory of Immune Microenvironment and Disease (Ministry of Education) The Province and Ministry Co‐sponsored Collaborative Innovation Center for Medical Epigenetics Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnostics School of Pharmacy Tianjin Medical University Tianjin 300070 China Key Laboratory of Longevity and Aging‐Related Diseases Ministry of Education Nanning China; Center for Translational Medicine Guangxi Medical University Nanning China State Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100101, China Institute of Island and Coastal Ecosystems, Ocean College, Zhejiang University, Zhoushan, China Institute of Functional Nano & Soft Materials, Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu 215123, China; Department of Obstetrics and Gynecology, Peking University, First Hospital, Beijing 100034, China. Department of Physics, Jiangsu Key Laboratory for Advanced Metallic Materials, Southeast University, Nanjing 211189, China Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China From the Departments of Radiology (Z.F., H.L., J.D., W.W., P.R.), Pathology (Q.C.), and Infectious Disease (Z.L.), The Third Xiangya Hospital of Central South University, No. 138 Tongzipo Rd, Changsha 410013, China; Department of Medical Imaging, Yueyang Central Hospital, Yueyang, China (Q.L., W.Z.); and Department of Diagnostic Radiology, Hunan Cancer Hospital, Changsha, China (X.Y.). Institute of Functional Nano & Soft Materials (FUNSOM) Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University Suzhou Jiangsu 215123 China Department of Pathology, Microbiology and Immunology & Forensic Medicine, Philadelphia College of Osteopathic Medicine, 4170 City Avenue, Philadelphia, PA 19131-1694, USA Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm College of Forestry and Landscape Architecture South China Agricultural University Guangzhou 510642 China Department of Orthopaedics, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island; Bone and Joint Research Center, The First Affiliated Hospital of Medical School, Frontier Institute of Science and Technology, Xi’an Jiaotong University, Xi’an, Shaanxi, China Division of Immunology, Boston Children’s Hospital, Boston, Massachusetts, USA; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA; Key Laboratory of Irradiation Preservation of Sichuan Province, Sichuan Institute of Atomic Energy, Chengdu, Sichuan, China Graduate School, Beijing University of Chinese Medicine Beijing 100029, China. Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Clinical Blood Transfusion Laboratory, Hainan Provincial Blood Center, Haikou 570311, Hainan Province, China,Email: [email protected]. Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China Laboratory of Human Retrovirology and Immunoinformatics, Applied and Developmental Directorate, Frederick National Laboratory, Frederick, Maryland, USA Departments of Medicine and Surgery, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903 Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois; and Philadelphia College of Osteopathic Medicine, Philadelphia, PA, United States. Electronic address: [email protected]. Department of Gastrointestinal Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China; Hubei Province Academy of Traditional Chinese Medicine, Wuhan, China; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China State Key Laboratory of Crop Biology, College of Agronomy, Shandong Agricultural University, Tai'an 271018, Shandong Province, China; State Key Laboratory of Plant Genomics, National Centre for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China Department of Plastic and Cosmetic Surgery, Hunan Provincial People's Hospital The First Affiliated Hospital of Hunan Normal University Changsha Hunan Province PR China Department of Orthopedics, People's Hospital of Linyi, Linyi, Shandong, China (mainland) CNS, Astellas Research Institute of America LLC, Skokie, Illinois, USA Center of Reproductive Medicine, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine 197 Ruijin Er Road, Huangpu, Shanghai 200025, China. Department of Histo-Embryology, Genetics and Developmental Biology, Shanghai Jiaotong University, School of Medicine 280 South Chongqing Road, Huangpu, Shanghai 200025, China. Shanghai Key Laboratory of Reproductive Medicine 280 South Chongqing Road, Huangpu, Shanghai 200025, China. Department of Histology and Embryology, Second Military Medical University, Shanghai, China School of Physics Southeast University Nanjing 211189 P.R. China Department of Mechanical Engineering and Materials Science University of Pittsburgh Pittsburgh PA 15261 USA Department of Pathology The first affiliated Hospital Third Military Medical University Chongqing 400037 China PhD, RN, Deputy Director, Center of Gerontology and Geriatrics, and National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Taiwan, ROC. Department of Physics Southeast University Nanjing 211189 China First College of Clinical Medicine, Zhejiang Chinese Medical University National Research and Development Center for Egg Processing; Huazhong Agriculture University; Wuhan 430070; China College of Environmental Science and Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China. College of Forestry, Shaanxi Key Laboratory of Economic Plant Resources Development and Utilization Northwest A&F University Yangling Shaanxi P. R. China College of Horticulture and Landscape, Tianjin Agricultural University, Tianjin 300384, China. State Key Laboratory of Photocatalysis on Energy and Environment College of Chemistry Fuzhou University Fuzhou 350108 P. R. China University of Electronic Science and Technology of China; Southern University of Science and Technology Traditional Chinese Medicine Hospital, Xinjiang Medical University, Ürümqi, China Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China, China. [email protected] The State Key Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and School of Basic Medicine Peking Union Medical College Beijing China National Space Science Center Chinese Academy of Sciences Beijing 100190 P. R. China; University of Chinese Academy of Sciences Beijing 100049 P. R. China Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing, China Institute of Photovoltaic Southwest Petroleum University Chengdu Sichuan 610500 China State Key Laboratory of Plant Genomics, National Centre for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences , Beijing 100101 , China; Institute of Physical Science and Information, Anhui University , Hefei 230039 , China Department of Health Statistics School of Public Health, Shanxi Medical University People's Republic of China Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi 710061, P. R. China; Key Laboratory of Environment and Genes Related to Diseases (Xi’an Jiaotong University), Ministry of Education of China, Xi’an, Shaanxi 710061, P. R. China Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China Department of Orthopaedics, Affiliated Hospital of North Sichuan Medical College, Nanchong City, China Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China (mainland) Department of Reproductive Medicine, The First Affiliated Hospital of the Medical College, Xi'an Jiaotong University, Xi'an, The People's Republic of China Department of Brain Disease, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China College of Chemistry and Materials Science Sichuan Normal University Chengdu 610068 P. R. China Key Laboratory for Analytical Science of Food Safety and Biology, MOE, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China Center for Translational Medicine (W.Y., X.K., X.J., Z.Q., T.X., N.Q., D.F., W.P., Q.C., S.W.), the First Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710061, People's Republic of China;; Frontier Institute of Science and Technology (Q.C.), Xi'an Jiaotong University, Xi'an, Shaanxi 710061, People's Republic of China;; Department of Orthopaedics (Q.C.), Brown University Alpert Medical School and Rhode Island Hospital, Providence, Rhode Island 02903 Department of Gastroenterology, National Medical Center for Major Public Events, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China Department of Gynecology and Obstetrics Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China Department of Infectious Diseases Renmin Hospital of Wuhan University China State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, P. R. China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Medicinal Chemistry, School of Pharmacy, Chongqing Medical University, Chongqing, China Centre of Pathophysiology Toulouse Purpan, INSERM U1043, CNRS UMR5282, Toulouse III University, Toulouse, France School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, China Authors' Affiliations: 1Department of Orthopaedics, Warren Alpert Medical School of Brown University and Rhode Island Hospital; and 2Surgical Service, Department of Veterans Affairs Medical Center, Providence, Rhode Island College of Food and Bioengineering, South China University of Technology, Guangzhou 510640, P. R. China.; Institute of Plant Virology, Fujian Agriculture and Forest University, Fuzhou 350002, P. R. China. Department of Psychiatry, University of Chicago, 924 East 57th Street, Chicago, IL 60637 Department of Pharmacy, Tongji Hospital Affiliated with Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials, and Department of Chemistry College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China Department of Pharmacy Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Biotechnology, College of Life Science, Nanjing University, Nanjing, Jiangsu, Province, China. School of Materials; University of Manchester; Manchester; UK Department of Physics Southeast University Nanjing 211189 P.R. China Department of Orthopaedics, Affiliated Hospital of Jiangsu University, Zhenjiang 212000, Jiangsu, China; [email protected]. College of Environmental Sciences and Engineering, Peking University, Key Laboratory of Water and Sediment Sciences, Ministry of Education, Beijing, PR People’s Republic of China; State Environmental Protection Key Laboratory of All Materials Flux in River Ecosystems, Beijing, People’s Republic of China Institute of Functional Nano & Soft Materials (FUNSOM); Collaborative Innovation Center of Suzhou Nano Science and Technology; Jiangsu Key Laboratory for Carbon-based Functional Materials and Devices; Soochow University; Suzhou Germplasm Bank of Wild Species, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China; Institute of Tibetan Plateau Research at Kunming, Chinese Academy of Sciences , Kunming 650201 , China State Key Laboratory of Crop Biology, College of Agronomy, Shandong Agricultural University, Taian, Shandong 271018, China Environmental Microbiome and Innovative Genomics Laboratory, College of Environmental Sciences and Engineering, Peking University , Beijing 100871, PR China; State Environmental Protection Key Laboratory of All Materials Fluxes in River Ecosystems, Peking University , Beijing 100871, PR China Department of Chemistry, The First Affiliated Hospital, Jinan University, Guangzhou, Guangdong 510632, People's Republic of China, Department of Medicine, Rhode Island Hospital, and Brown University School of Medicine, Providence, Rhode Island 02903 Eye Institute of Xiamen University, Xiamen, Fujian 361000, China Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China. Cell and Molecular Biology Laboratory, Department of OrthopaedicsAlpert Medical School of Brown University/Rhode Island Hospital Providence Rhode Island USA Department of Cardiology, Sun Yat‑sen Memorial Hospital of Sun Yat‑sen University, Guangzhou, Guangdong 510000, P.R. China Health Management Center, Deyang People's Hospital Deyang China Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, PR China 2Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope, Duarte, California. Institute of Functional Nano & Soft Materials (FUNSOM) Collaborative Innovation Center of Suzhou Nano Science and Technology Jiangsu Key Laboratory for Carbon‐based Functional Materials and Devices Soochow University Suzhou Jiangsu 215123 P. R. China College of Marxism, Fujian Agriculture and Forestry University, Fuzhou 350002, China Department of Clinical Laboratory, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China *Laboratory of Molecular Immunoregulation, Center for Cancer Research, and Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, MD; and Department of Chemistry Guangdong-Hong Kong-Macao Joint Laboratory for Photonic-Thermal-Electrical Energy Materials and Devices Southern University of Science and Technology Shenzhen 518055, Guangdong China Department of Plastic and Cosmetic Surgery Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University Changsha Hunan Province People's Republic of China Anhui Key Laboratory of Bioactivity of Natural Products, School of Pharmacy, Anhui Medical University, Hefei, PR China Sichuan University of Science and Engineering Zigong 643000 P. R. China Department of Anesthesiology, Southwest Hospital, Third Military Medical University, Chongqing, China Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China Orthopedics, Affiliated Hospital of North Sichuan Medical College, Nanchong, China State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China Department of Ophthalmology, Fudan Eye & ENT Hospital, Shanghai, China Department of Pathology and Center of Infection and Immunology, The University of Hong Kong, Hong Kong, China Medical Affairs Department Peking Union Medical College Hospital, Chinese Academy of Medical Sciences Beijing China Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University Suzhou Jiangsu 215123 China Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, 199 Ren’ai Road, Suzhou 215123, Jiangsu P.R. China; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, United States State Key Laboratory of Natural and Biomimetic Drugs Department of Molecular and Cellular Pharmacology School of Pharmaceutical Sciences Peking University Health Science Center Beijing 100191 China Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States Cell and Molecular Biology Laboratory, Department of Orthopaedics, Brown Medical School/Rhode Island Hospital, Providence, Rhode Island, USA Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China Drug Clinical Trial Center, Shanghai Xuhui Central Hospital / Zhongshan – Xuhui Hospital, Fudan University, Shanghai, 200031, China; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, 200031, China Department of Bioengineering University of California Los Angeles CA 90095 USA; California NanoSystems Institute University of California Los Angeles CA 90095 USA; Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon‐Based Functional Materials and Devices Soochow University Suzhou 215123 P. R. China Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics; School of Pharmacy; Tianjin Medical University; Tianjin 300070; P. R. China College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, China Institute of Pediatrics, Children's Hospital of Nanjing Medical University No.72 Guangzhou Road, Nanjing 210008, China. School of Electronic Information Engineering, Taiyuan University of Science and Technology, Taiyuan, China Tianjin State Key Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China Nanjing Drum Tower Hospital Group Suqian People's Hospital Suqian, China. Department of Oncology, The Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China (mainland) Smart Computational Imaging Laboratory(SCILab), School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu Province 210094, China College of Chemistry and Materials Science; Sichuan Normal University; Chengdu 610068; China College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang, China State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, 550004, People’s Republic of China Department of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine Graduate School of Peking Union Medical College, Beijing 100730, China. Key Laboratory of Green Chemistry & Technology of MOE, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, China Liver Unit, Liver Disease Laboratory-Viral Hepatitis, Internal Medicine Department, Vall d’Hebron Institut Recerca (VHIR)-Hospital Universitari Vall d’Hebron (HUVH), 08035, Barcelona, Spain Department of Spine Surgery, the Third Hospital of Hebei Medical University, Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, China. Department of OrthopaedicsWarren Alpert Medical School of Brown University/Rhode Island Hospital (RIH), ProvidenceRhode IslandUSA *Section of Molecular Cell and Developmental Biology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712; and Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University Guilin, 541001, Guangxi, People's Republic of China. Country State Key Laboratory of High Performance Ceramics and Superfine Microstructure; Shanghai Institute of Ceramics; Chinese Academy of Sciences; Shanghai 200050; P. R. China Department of Orthopedic Surgery Zhongshan Hospital Fudan University Shanghai 200032 China Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University of Medicine, Shanghai, 200092, China State Key Laboratory of Natural and Biomimetic Drugs Department of Molecular and Cellular Pharmacology School of Pharmaceutical Sciences Peking University Health Science Centre Beijing 100191 China State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China State Key Laboratory of Agro‐Biotechnology College of Biological Sciences China Agricultural University Beijing 100193 People's Republic of China Pathogenic Biology Institute, Medical College, University of South China, 28 West Changsheng Road, Hengyang, Hunan 421001, China School of Materials Science and Engineering, International S&T Cooperation Foundation of Shaanxi Province, Shaanxi University of Science and Technology, Xi'an 710021, China School of Pharmacy & State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University 550025 Guiyang P. R. China Wuhan National Laboratory for Optoelectronics and College of Optoelectronic Science and Engineering Huazhong University of Science and Technology Wuhan 430074 China College of Acupuncture, Moxibustion and Orthopaedics, Hubei Provincial Collaborative Innovation Center of Preventive Treatment of Disease with Acupuncture and Moxibustion, Hubei University of CM, Wuhan 430061, China. State Key Laboratory of Mycology Institute of Microbiology Chinese Academy of Sciences Beijing 100101 China Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland, WA 99352;; Key Laboratory for Aerosol-Cloud-Precipitation of China Meteorological Administration, Nanjing University of Information Science and Technology, Nanjing 210044, China; Department of Nephrology, Molecular Cell Lab for Kidney Disease, Shanghai Peritoneal Dialysis Research Center, Ren Ji Hospital, Uremia Diagnosis and Treatment Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, School of Pharmacy, Anhui Medical University, Hefei,China State Key Laboratory of Component‐based Chinese Medicine Tianjin University of Traditional Chinese Medicine. 10 Poyanghu Road Jinghai District Tianjin 301617 China; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae (Tianjin University of Traditional Chinese Medicine) Ministry of Education 312 Anshanxi Road Nankai District Tianjin 300193 China; Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine. 10 Poyanghu Road Jinghai District Tianjin 301617 China Institute of Functional Nano and Soft Materials, Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou 215123, China; Department of Pediatrics, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People's Republic of China. Key Laboratory of Materials Physics Institute of Solid State Physics HFIPS Chinese Academy of Sciences Hefei 230031 P. R. China; University of Science and Technology of China Hefei 230026 P. R. China Shaanxi Institute of Flexible Electronics (SIFE), Northwestern Polytechnical University (NWPU), 127 West Youyi Road, Xi'an 710072, P. R. China Department of Health Management, The Third Xiangya Hospital, Central South University Department of Chemistry and Nano Science Ewha Womans University Seoul Korea College of Horticulture Science and Enginee-ring, Shandong Agricultural University/State Key Laboratory of Crop Biology, Tai'an 271018, Shandong, China. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China, Key State Laboratory of Applied Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China, State Key Laboratory of Molecular Dynamics and Stable Structures, College of Chemistry, Peking University, Beijing 100871, China, and Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China [email protected]; [email protected] Shenzhen Children Hospital, Shenzhen, China Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200030, China Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States Department of General Surgery, Minhang Hospital, Fudan University China. Echocardiography and Vascular Ultrasound Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang 310003, China National Clinical Research Center for Geriatric Disorders , Department of Geriatrics, Xiangya Hospital, , Changsha 410008, China; Central South University , Department of Geriatrics, Xiangya Hospital, , Changsha 410008, China; Department of Neurology , Xiangya Hospital, , Changsha 410008, China; Central South University , Xiangya Hospital, , Changsha 410008, China Department of Cardiology, Sun Yat-sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510010, China Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, People's Republic of China Department of Radiation Oncology, Tenth People’s Hospital Affliated to Tongji University, Shanghai 200072, China Occupational Health and Launch Health Institute Yunnan Center for Disease Control and Prevention Kunming China; School of Public Health Dali University Dali China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, People's Republic of China. Department of Clinical Pharmacology, Chinese People's Liberation Army General Hospital, Beijing 100853, China. Irradiation Preservation Technology Key Laboratory of Sichuan Province Sichuan Institute of Atomic Energy Chengdu China Department of Clinical Medicine Guizhou Medical University Guiyang Guizhou China Shanghai Xuhui Central Hospital Shanghai China College of Biomass Science and Engineering Sichuan University Chengdu China Department of Medicine, University of Cincinnati School of Medicine, Cincinnati MSB 5502; and College of Food Science Northeast Agricultural University Harbin China Section of Molecular Cell & Developmental Biology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712 Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai, 200032, P. R. China Soochow Univ, Inst Funct Nano & Soft Mat FUNSOM Jiangsu Key Lab Carbon Based Funct Mat & Devices Suzhou 215123 P. R. China) # Chao Gu and Xueliang Liu contributed equally to this work. Department of Materials Science and Engineering University of Illinois Urbana IL 61801 USA; Materials Research Laboratory University of Illinois Urbana IL 61801 USA; Department of Chemical and Biomolecular Engineering University of Illinois Urbana IL 61801 USA; Department of Chemistry University of Illinois Urbana IL 61801 USA; Beckman Institute for Advanced Science and Technology University of Illinois Urbana IL 61801 USA Department of Biomedical Engineering Southern University of Science and Technology Shenzhen China; School of Physics University of Electronic Science and Technology of China Chengdu China Department of Radiology, Nanjing First Hospital Nanjing Medical University Nanjing China Irradiation Preservation Technology Key Laboratory of Sichuan Province, Sichuan Institute of Atomic Energy, Chengdu 610101, China Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China From the Basic Research Program, SAIC-Frederick, MD; Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD; Eosinophil Pathophysiology Section, Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD. The Center of Gerontology and Geriatrics, West China Hospital/West China School of Nursing, Sichuan University, No. 37, Guoxue Alley, Chengdu, Sichuan, China. Department of Obstetrics and Gynecology West China Second University Hospital, Sichuan University Chengdu China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University) Ministry of Education Sichuan China Department of Cardiovascular Surgery, Changhai Hospital Naval Medical University Shanghai China Department of Food Safety and Nurition, Beijing Center for Disease Control and Prevention; Beijing Key Laboratory of Diagnostic and Traceability Techonolgies for Food Poisoning, Beijing 100013, China. Email: [email protected]. College of Agriculture and Animal Husbandry, Qinghai University, Xining, Qinghai, P.R. China; School of Life Science, Qilu Normal University, Jinan, Shandong, P.R. China State Key Laboratory of Featured Metal Materials and Life‐Cycle Safety for Composite Structures School of Resources, Environment and Materials Guangxi University Nanning 530004 P. R. China Department of Chemistry, University of California, Berkeley, CA 94720, USA.; Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.; Miller Institute for Basic Research in Science, University of California, Berkeley, CA 93720, USA. School of Materials Science and Engineering Beihang University Beijing 100191 P. R. China State Key Laboratory of Plant Genomics, National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China Department of Chemical Engineering, School of Environmental and Chemical Engineering, Shanghai University, 99 Shangda Road, Shanghai 200444, P. R. China Division of Immunology Boston Children's Hospital Boston Massachusetts USA; Department of Pediatrics Harvard Medical School Boston Massachusetts USA Department of Ophthalmology, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China; Shanghai Key Laboratory of Fundus Disease Shanghai Jiao Tong University School of Medicine Shanghai China Laboratory of Molecular Immunoregulation, Center for Cancer Research , Maryland , USA Department of Orthopaedics; Warren Alpert Medical School of Brown University/RIH; CORO West; Suite 402H; 1 Hoppin Street Providence Rhode Island 02903 Medical Research Center, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China Division of Cardiovascular Diseases and the Gonda Vascular Center, Mayo Clinic, Rochester, MN; Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China Department of Pain Medicine, Orthopedic Hospital of Guizhou Province, Guiyang 550002, Guizhou, China Department of Respiratory & Critical Care Medicine, Taizhou Hospital, Zhejiang University, Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang Province, 317000, China Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Eye Institute of Xiamen University & Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen University, Xiamen, Fujian, China Laboratory Center, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, China (mainland) 1Department of Orthopaedics, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island. Institute of Functional Nano and Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon‐Based Functional Materials and Devices Soochow University 199 Ren'ai Road Suzhou Jiangsu 215123 P. R. China College of Sciences, Xi’an University of Science and Technology, Xi’an, Shaanxi 710054, P. R. China Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China 3Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.; 6Thorgene Co., Ltd., Beijing, China. Department of Orthopaedic Surgery, The Affiliated Taizhou People’s Hospital of Nantong University, Taizhou, China; Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China Department of Orthopaedic Surgery, Zhongshan Hospital, Fudan University 180 Fenglin Road, Shanghai 200032, China. School of Electronic and Optical Engineering Nanjing University of Science and Technology Nanjing China; Jiangsu Key Laboratory of Spectral Imaging & Intelligent Sense Nanjing China State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; The Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China Department of General Surgery, Minhang Hospital, Fudan University, Shanghai, China The First Affiliated Hospital, Institute of Medicine, Jishou University, Jishou, Hunan 416000, P.R. China Division of Gastroenterology, Department of Internal Medicine at Tongji Hospital, Tongji Medical College, HUST, Wuhan, China Department of Orthopaedics Alpert Medical School of Brown University/Rhode Island Hospital Providence Rhode Island; Bone and Joint Research Center, The First Affiliated Hospital Frontier Institute of Science and Technology, Xi'an Jiaotong University Xi'an China Sinopec Petroleum Exploration and Production Research Institute, 100083, China College of Chemistry and Material Sciences, School of Life Science, Heilongjiang University, Harbin 150080, China Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, China Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, and Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing, China Department of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China Department of Animal, Plant and Soil Sciences and La Trobe Institute for Agriculture and Food (LIAF), ARC Centre of Excellence in Plant Energy Biology, School of Life Sciences, La Trobe University, Bundoora VIC 3086, Australia From the Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, China (X.C., Q.C., Y.L., W.L.); Guangdong Provincial Key Laboratory of Food, Nutrition, and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, China (X.C., Q.C., Y.L., W.L.); Department of Cardiology, General Hospital of Guangzhou Military Command of People’s Liberation Army, China (Y.Z.); and Department of Epidemiology, School of Public Health, Guilin Medical... Department of Physics, Southeast University, Nanjing, 211189, China Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Xi’an Jiaotong University Health Science Center Xi’an China; Key Laboratory of Environment and Genes Related to Diseases Ministry of Education Xi’an Shaanxi China Department of Ophthalmology, Eye Ear Nose and Throat Hospital of Fudan University, Shanghai 200031, China. Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, China. School of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou, Gansu, China; Shouhang Hi-Tech Energy Technology Co. Ltd, Lanzhou, Gansu, China; Key Laboratory of Fluid and Power Machinery, Ministry of Education, Xihua University, Chengdu, Sichuan, China Department of Biomedical Engineering Southern University of Science and Technology Shenzhen Guangdong China; School of Electronic Science and Engineering University of Electronic Science and Technology of China Chengdu Sichuan China Department of Neurosurgery, Capital Institute of Pediatrics, Beijing, China Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Department of Neurosurgery or Neurology, Capital Institute of Paediatrics, Beijing, China Ministry of Education‐Shanghai Key Laboratory of Children's Environmental Health, Xin Hua Hospital Shanghai Jiao Tong University School of Medicine Shanghai China State Key Lab Plateau Ecology and Agriculture, Qinghai University, Xining, People’s Republic of China Department of Bioengineering; California Nanosystems Institute and Center for Minimally Invasive Therapeutics; University of California; Los Angeles; USA Cancer Center Daping Hospital, Army Medical University Chongqing China Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China. Email: [email protected]. Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, People’s Republic of China Department of General Surgery, Minhang Hospital, Ruijin Hospital Group, Shanghai, China. Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China Beijing Institute of Basic Medical Sciences, Beijing 100850, China. Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P. R. China Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, P.R. China Department of Pediatric Neurology Capital Institute of Pediatrics Beijing China Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China, State Key Laboratory of Molecular Dynamics and Stable Structures, College of Chemistry, Peking University, Beijing 100871, China, and Department of Chemistry, Hong Kong University of Science and Technology, Hong Kong, China Department of Pediatrics, Guangdong General Hospital, Guangdong Academy of Neuroscience, Guangdong Academy of Medical Sciences, Guangzhou 510080, China Key Laboratory of Intelligent Textile and Flexible Interconnection of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou 310018, China; Engineering Research Center for Eco-Dying & Finishing of Textiles, Ministry of Education, Zhejiang Sci-Tech University, Hangzhou 310018, China School of Materials Science and Engineering, Beihang University, Beijing 100191, China Frontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), and Beijing Key Laboratory of Crop Genetic Improvement China Agricultural University Beijing China Department of Respiratory and Critical Care Medicine, Taizhou Hospital Zhejiang University, Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang Province, 318050, China Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, China. [email protected] Key laboratory of Traditional Chinese Medicine Resource and Compound Prescription, Hubei University of Traditional Chinese Medicine, Wuhan 430065, China. [email protected] ‡ Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702; Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences , 32 Xiqidao, Tianjin Airport Economic Park, Tianjin 300308, China Faculty of Basic Medical Sciences, Kunming Medical University, Kunming 650500, China *Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, 07745 Jena, Germany; Department of Geriatric Cardiology, PLA General Hospital, Beijing 100853, China. Department of Traditional Chinese Medicine, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huaian City, Jiangsu Province, China Department of Orthodontics School of Stomatology Shandong University Jinan Shandong Province China 1State Key Laboratory of Pharmaceutical Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of life sciences, Nanjing University, Nanjing, China. Department of Gynecologic Oncology, Hubei Cancer Hospital, Wuhan, Hubei 430079, P.R. China Department of Biological Sciences, The University of Toledo, Toledo, OH 43606; Departments of Molecular Cellular and Developmental Biology From the Department of Nutrition, School of Public Health (C.Y., H.X., L.W., Q.C., X.C., W.L.) Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing, P. R. China 1000084 West China School of Pharmaceutical Science, Si Chuan University, Chengdu 610041, China. Beijing Municipal Center for Disease Prevention and Control, Beijing, China. Shanghai East Hospital, The Institute for Biomedical Engineering & Nano Science, Tongji University School of Medicine, Shanghai, China; Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Soochow University, 199 Ren'ai Road Suzhou China Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK Department of Neurology, Capital Institute of Pediatrics, Beijing 100020, China. School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China; Key Laboratory of Special Energy Materials, Ministry of Education, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China State Key Laboratory of Pharmaceutical Biotechnology Medical School and School of Life Science Nanjing University Nanjing 210093 P. R. China Drug Clinical Trial Center Shanghai Xuhui Central Hospital/Xuhui Hospital, Fudan University Shanghai China; Shanghai Engineering Research Center of Phase I Clinical Research and Quality Consistency Evaluation for Drugs Shanghai China Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, China School of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China Department of Pediatric Neurology, Capital Institute of Pediatrics, Beijing, China Institute of Functional Nano & Soft Materials (FUNSOM) The Jiangsu Key Laboratory for Carbon‐Based Functional Materials & Devices Soochow University Suzhou 215123 P. R. China Department of Infectious Diseases Renmin Hospital of Wuhan University Wuhan China Department of Spine Surgery, The Third Hospital of Hebei Medical University 139 Ziqiang Road, Shijiazhuang 050051, China. College of Animal Husbandry and Veterinary Medicine Shenyang Agricultural University Shenyang China Laboratory of Human Retrovirology and Immunoinformatics Frederick National Laboratory for Cancer Research Frederick MD USA Neurology Department, Capital Institute of Pediatrics, Beijing, China Department of Bioengineering University of California Los Angeles CA 90095 USA; California NanoSystems Institute Jonsson Comprehensive Cancer Center and Center for Minimally Invasive Therapeutics University of California Los Angeles CA 90095 USA; Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University Raleigh NC 27695 USA State Key Laboratory of Clean Energy Utilization, Institute for Thermal Power Engineering, Zhejiang University, Hangzhou, 310027 Zhejiang, China; Zhejiang University Qingshanhu Energy Research Center, Linan, 311305 Hangzhou, P. R. China Nanotechnology and Intestinal Microecology Research Center Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China College of Life Sciences and Health, Wuhan University of Science and TechnologyHubeiP.R. China CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; Institutes of Physical Science and Information Technology, Anhui University, Hefei, China Department of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou City, Jiangsu Province, China. Department of Spinal Surgery, Luoyang Orthopedic Hospital of Henan Province, Zhengzhou Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.; Miller Institute for Basic Research in Science, University of California, Berkeley, Berkeley, CA 94720, USA. c Centre of Pathophysiology Toulouse Purpan INSERM U1043, CNRS UMR5282, Toulouse III University, Toulouse, France Department of Ophthalmology Eye Ear Nose and Throat Hospital of Fudan University Shanghai China; State Key Laboratory of Medical Neurobiology Institutes of Brain Science Fudan University Shanghai China Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangdong, China; Chronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA Department of Physiology University of Oklahoma Health Sciences Center Oklahoma City OK USA Department of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China; Institute of Medical Imaging and Artificial Intelligence, Nanjing University, Nanjing, China; Medical Imaging Center, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China Department of Pharmacy, Changzhou University, Changzhou, PR China The Academy of Fundamental and Interdisciplinary Science, Harbin Institute of Technology Department of Radiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, People’s Republic of China Department of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Key Laboratory of Agric-Environment and Agric-Products Safety, College of Agriculture, Guangxi University, Nanning 530004, China Department of Clinical Laboratory Peking Union Medical College Hospital Beijing China School of Nano‐Tech and Nano‐Bionics University of Science and Technology of China Hefei 230026 China; CAS Key Laboratory of Nano‐Bio Interface Division of Nanobiomedicine and i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences Suzhou 215123 China; North District of Suzhou Municipal Hospital The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou 215008 China School of Marine and Technology, Harbin Institute of Technology, Weihai 264209, China Department of Physics; Southeast University; Nanjing 211189; China Department of Encephalopathy, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China School of Materials Science and Engineering, Beihang University, Beijing 100191, P. R. China Institute of Functional Nano and Soft Materials (FUNSOM) and Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University Suzhou Jiangsu 215123 China Department of Radiology The Affiliated Suzhou Hospital of Nanjing Medical University Suzhou 215000 China Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, China Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University Raleigh NC 27695 USA; Department of Bioengineering University of California, Los Angeles Los Angeles CA 90095 USA; California NanoSystems Institute University of California, Los Angeles Los Angeles CA 90095 USA Department of Liver Surgery Institute of Molecular Medicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai Institute of Transplantation Shanghai 200127 China Laboratory of Immunology, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Institute of New Type Optoelectronic Materials and Technology, College of Big Data and Information Engineering, Guizhou University, Guiyang, 550025, China; State Key Laboratory of Public Big Data, Guizhou University, 550025, China Department of Chemistry, South University of Science and Technology of China, Shenzhen, P. R. China Southeast University 1 Department of Physics, , Nanjing 211189, People’s Republic of China Department of Microbial Ecology, Groningen Institute for Evolutionary Life Sciences, University of Groningen, The Netherlands Department of Pathology, The Third Xiangya Hospital of The Central South University Changsha, Hunan, China. Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China; Minhang Hospital, Fudan University, 170 Xinsong Road, Shanghai 201199, China Department of Traditional Chinese Medicine, The Affiliated Huaian NO.1 People’s Hospital of Nanjing Medical University, Huaian City, Jiangsu Province 223300, China University of Electronic Science and Technology of China Longbai Community Health Service Center of Minhang District, Shanghai, China. Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD Key Laboratory of Luminescent and Real‐Time Analytical Chemistry Ministry of Education College of Chemistry and Chemical Engineering Southwest University Chongqing China Functional Nano & Soft Materials Laboratory (FUNSOM) and Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu 215123, China Molecular Biology Research Center, College of Biological Science and Technology, Central South University, Changsha 410078, China. State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Vector-borne Virus Research Center, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany; Vector-borne Virus Research Center, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China Department of Chemistry, University of California at Berkeley, Berkeley, California 94720, United States; Miller Institute for Basic Research in Science, University of California at Berkeley, Berkeley, California 94720, United States Key Laboratory of Bioresources and Ecoenvironment (Ministry of Education), College of Life Sciences, Sichuan University, Chengdu 610064, China College of Horticulture Science and Engineering, Shandong Agricultural University/State Key Laboratory of Crop Biology, Tai'an 271018, Shandong, China. School of Advanced Manufacturing, Fuzhou University, Jinjiang 362200, People's Republic of China Department of Cancer Genetics and Epigenetics City of Hope Duarte CA USA Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute at Frederick , Maryland Department of Microbiology and Immunology, Medical College, Jinan University, Guangzhou 510632, China. Department of Neurology, The First People’s Hospital of Ziyang, Ziyang 641300, Sichuan, China Key Laboratory of Materials Physics Institute of Solid State Physics HFIPS Chinese Academy of Sciences Hefei 230031 P. R. China; Science Island Branch of Graduate School University of Science and Technology of China Hefei 230026 P. R. China Department of Chemistry, Southern University of Science and Technology, Shenzhen, Guangdong 518000, People’s Republic of China From the Institute of Neuroscience (M.C., T.-J.L., X.-J.C., Y.Z., Q.C., X.-Y.F., L.X., Z.-Q.X.), State Key Laboratory of Neuroscience, Shanghai, China; and the Shanghai Institute of Materia Medica Shanghai Institutes for Biological Sciences (W.-H.D.), Chinese Academy of Sciences, Shanghai, China. State Key Laboratory of Natural and Biomimetic Drugs, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, 100191, China Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany; Department of Bioengineering, School of Resources Processing and Bioengineering, Central South University, Changsha, Hunan 410083, P. R. China. Jilin Province Key Laboratory of Carbon Fiber Development and Application; School of Chemistry and Life Science; Changchun University of Technology; Changchun 130012; P. R. China Provincial Key Laboratory of Ophthalmology and Visual Science, Eye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China Laboratory of Molecular Immunoregulation, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Frederick, MD 21702 College of Pharmacy, Qingdao University, Qingdao, Shandong, P. R. China Department of Epidemiology and Health Statistics, Xiangya School of Public Health Central South University Changsha China PhD, RN, Associate Professor, Center of Gerontology and Geriatrics, and National Clinical Research Center of Geriatrics, West China Hospital, Sichuan University, Taiwan, ROC. Oncology Center, Renmin Hospital of Wuhan University, Wuhan - China Ultrasonography Center of Obstetrics and Gynecology Renmin Hospital of Wuhan University Wuhan China National Clinical Research Center for Geriatric Disorders, Department of Geriatrics, Xiangya Hospital Central South University Changsha China Institute of Flexible Electronics (IFE) Northwestern Polytechnical University (NPU) 127 West Youyi Road Xi'an 710072 P. R. China Department of Cardiology the Second Medical Center, Chinese PLA General Hospital, National Clinical Research Center for Geriatric Diseases Beijing China Department of Psychiatry, University of Chicago, Chicago, IL 60653 Department II of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China Institute of Functional aNano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu 215123, China Department of Nuclear Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072 Sichuan Province, China State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang 550004, People’s Republic of China Department of Orthopaedics, Warren Alpert Medical School of Brown University/Rhode Island Hospital, Providence, RI, USA State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, 100193, China; Key Laboratory of Crop Heterosis and Utilization (Ministry of Education), China Agricultural University, Beijing, 100193, China; Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing, 100193, China Department of Cardiovascular Surgery, Institute of Cardiac Surgery, Changhai Hospital, Naval Medical University, Shanghai, China Department of Physiology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States Department of Clinical Medicine, Guizhou Medical University, Guiyang, China Department of Molecular Biology and Genetics Johns Hopkins University School of Medicine Baltimore MD USA Department of Biological Sciences, University of Toledo, Toledo, OH 43606 Department of Supply Chain and Information Systems, Penn State University, University Park, PA Biomedical Analysis Center, Third Military Medical University (Army Medical University), Chongqing 400038, China |
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