http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_e3b917e695ee0750d5519808320a92d9
Outgoing Links
Predicate | Object |
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family-name | Zhang Ting Zhang |
name | Ting Zhang |
given-name | Ting |
organization-name | Department of Orthopaedics, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710000, P.R. China College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, P. R. China Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China (mainland) Beijing Municipal Key Laboratory of Child Development and Nutriomics Capital Institute of Pediatrics Beijing 100020 China Department of Chemistry Institute of Molecular Plus Tianjin Key Laboratory of Molecular Optoelectronic Science Tianjin University Tianjin 300072 China Department of Hematology Wuhan No.1 Hospital Wuhan China School of Population Medicine & Public Health, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, China. Data Biotech (Beijing) Co., Ltd. Beijing China Department of Pharmacology, College of Pharmacy, the Inner Mongolian Medical University, Jinshan Development, Hohhot, 010110, Inner Mongolia Autonomous Region, China School of Nursing Anhui Medical University Hefei China School of Materials Science and Engineering, Hefei University of Technology, Hefei, Anhui, 230009, P. R. China Department of Breast Surgery Southwest Hospital, the Third Military Medical University Chongqing 400038 China Department of Biotechnology, Beijing Municipal Key Laboratory of Child Development and Nutriomics Capital Institute of Pediatrics Beijing 100020 China Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China. School/Hospital of Stomatology Lanzhou University, Lanzhou 730000, China Key Laboratory of Bio‐Resource and Eco‐Environment of the Ministry of Education College of Life Science Sichuan University Chengdu 610065 China Department of Ophthalmology, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China 2Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China School of Physics, State Key Laboratory of Crystal Materials, Shandong University, Shandanan Str. 27, Jinan 250100, People's Republic of China Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York School of Basic Medical Sciences, Harbin Medical University, Heilongjiang, People’s Republic of China Capital Institute of Pediatrics, Beijing, China (mainland) Ting Zhang, Shi-Tao Zou, Fen Liu, Institute of Cancer, Affiliated hospital of Jiangnan University, Wuxi 214062, Jiangsu Province, China. Shanghai Key Laboratory of Regulatory Biology, The Institute of Biomedical Sciences & School of Life Sciences, East China Normal University, Shanghai, 200241, China Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Co‐innovation Center of Henan Province for New Drug R & D and Preclinical Safety, Institute of Drug Discovery and Development, Zhengzhou University Zhengzhou Henan China Department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai New York New York USA Department of Otorhinolaryngology, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, China *Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA 19111; Division of Immunogenetics, Department of Pediatrics, Children’s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania Department of Breast Surgery, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Henan 471003, P.R. China School of Chemistry and Chemical Engineering, Shanghai Key Lab of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. China Department of Clinical Nutrition State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of China Key Laboratory of Macromolecular Science of Shaanxi Province Shaanxi Engineering Lab for Advanced Energy Technology School of Chemistry and Chemical Engineering Shaanxi Normal University Xi'an 710119 China Yunnan Provincial Key Laboratory of Public Health and Biosafety and School of Public Health, Kunming Medical University, Kunming 650500, China State Key Laboratory of Medicinal Chemical Biology Tianjin Key Laboratory of Biosensing and Molecular Recognition College of Chemistry Nankai University Tianjin 300071 China State Key Laboratory of Supramolecular Structure and Materials; College of Chemistry Jilin University; Changchun 130012; P. R. China Jiangsu Provincial Research Center for Animal Transgenesis and Biopharming, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China. Children’s Hospital Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Department of Biochemistry and Immunology, Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education East China Normal University Shanghai China Department of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China. State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710079, China State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA Department of Gastroenterology, Hepatology and Nutrition Shanghai Children's Hospital Shanghai Jiao Tong University Shanghai China Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, P. R. China Department of Thyroid Surgery The First Hospital of China Medical University Shenyang P. R. China Department of Breast Surgery The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology Luoyang China State Key Laboratory of Drug Research, Shanghai Institue of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health Southeast University Nanjing People's Republic of China College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150086, China Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Institute of Pharmaceutical and Medical Devices Supervision, National Medical Products Administration-Chinese Academy of Medical Sciences, Beijing, China i-LAB, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, Jiangsu 215123, China School of Psychological and Cognitive Sciences, PKU-IDG/McGovern Institute for Brain Research, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China Departments of Chemistry and Pharmacology (J.F.D., K.R.R., T.Z., R.T.K.), University of Michigan, Ann Arbor, Michigan 48109; Department of Physics and William Mong Institute of Nano Science and Technology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China State Key Laboratory of Oncogenes and Related Genes School of Biomedical Engineering Institute for Personalized Medicine Shanghai Jiao Tong University Shanghai People's Republic of China Department of Obstetrics Beijing Obstetrics and Gynecology Hospital, Capital Medical University Beijing China State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211800, PR China Department of Rehabilitation Children's Hospital of Chongqing Medical University Chongqing China Department of Neurobiology, NHC and CAMS Key Laboratory of Medical Neurobiology, School of Brain Science and Brian Medicine, and the MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou 310058, China. Institute of Medical Information & Library, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100020, China Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi’an Jiaotong University, Xi’an 710061, China Department of Orthodontics Peking University School and Hospital of Stomatology Beijing China; National Clinical Research Center for Oral DiseasesNational Engineering Laboratory for Digital and Material Technology of Stomatology Beijing China; Beijing Key Laboratory of Digital Stomatology Beijing China Department of Breast and Thyroid Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and Barcelona Institute of Science and Technology (BIST), Campus UAB, Bellaterra, Barcelona, Catalonia 08193, Spain Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan;; Eye and ENT Hospital, Fudan University, Shanghai, China; and Beijing Municipal Key Laboratory of Child Development and Nutriomics Capital Institute of Pediatrics Beijing China Department of Oral and Maxillofacial Plastic and Traumatic Surgery, Beijing Stomatological Hospital, Capital Medical University, Beijing, China Department of Chemistry, Stanford University, Stanford, California 94305-5080, United States Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, People's Republic of China Institute of Engineering Thermophysics Innovation Academy for Light‐duty Gas Turbine Chinese Academy of Sciences Beijing 100190 China; Nanjing Institute of Future Energy System Nanjing 211135 China Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials & Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Wuhan 430062, China Department of Anatomy and K. K. Leung Brain Research Centre, Fourth Military Medical University, Xi’an 710000, China State Key Ophthalmic Laboratory Zhongshan Ophthalmic Center Sun Yat‐sen University Guangzhou China School of Psychological and Cognitive Sciences; PKU-IDG/McGovern Institute for Brain Research,; Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China School of Sport Science, Key Laboratory of the Ministry of Education of Exercise and Physical Fitness, Beijing Sport University, Beijing, China Department of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, People's Republic of China.; Liaoning Provincial Key Laboratory of Medical Cellular and Molecular Biology, Dalian Medical University, Dalian, People's Republic of China. Pharmacokinetics Laboratory Tianjin Institute of Medical & Pharmaceutical Sciences Tianjin China Department of Microbiology and Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, China. State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China Stomatological Hospital of Chongqing Medical University , No. 426 Songshibei Road, Yubei District , Chongqing 401147, China; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences , Chongqing 401147, China; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education , Chongqing 401147, China College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health & Collaborative Innovation Center of Suzhou Nano Science and Technology Southeast University Nanjing 210009 China; Jiangsu Key Laboratory for Biomaterials and Devices Southeast University Nanjing 210009 China Department of Thyroid Surgery The First Affiliated Hospital of China Medical University Shenyang Liaoning Province China School of Medicine, Huzhou University, Huzhou, Zhejiang, China (mainland) Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China Cancer Immunity Research Laboratory, Tianjin Institute of Urology, The Second Hospital of Tianjin Medical University, Tianjin Medical University, Tianjin 300211, P.R. China Molecular Modeling and Biopharmaceutical Center University of Kentucky 789 South Limestone Street Lexington Kentucky 40536 USA; Department of Pharmaceutical Sciences, College of Pharmacy University of Kentucky 789 South Limestone Street Lexington Kentucky 40536 USA Capital Institute of Pediatrics, Beijing 100020, China. Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang 110000, China School of Physics, Shandong University, Jinan 250100, People’s Republic of China Department of Thoracic, Cardiac, and Great Vascular Surgery, Taihe Hospital Hubei University of Medicine Shiyan China Guangdong Key Laboratory of Plant Adaptation and Molecular Design, Guangzhou Key Laboratory of Crop Gene Editing, Innovative Center of Molecular Genetics and Evolution, School of Life Sciences, Guangzhou University, Guangzhou 510006, China Department of Ophthalmology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai 200031, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai 200031, China i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences Suzhou 215123 P. R. China Henan Key Laboratory of Polyoxometalate Chemistry, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, P. R. China Key Laboratory of Preclinical Study for New Drugs of Gansu Province, and Institute of Physiology, School of Basic Medical Sciences, Lanzhou University, 199 Donggang West Road, Lanzhou, 730000, PR China Shanghai Hengrui Pharmaceutical CO., LTD., 279 Wenjing Road, Shanghai 200245, China College of Food Science and Engineering Ocean University of China Qingdao Shandong, Province PR China Digestive Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine), Nanjing, China Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, 200030 Shanghai, China; Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, P.R. China Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China; Institue of Pediatric Infection, Immunity and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Laboratory of Stem Cell Biology, West China Hospital, Sichuan University, Chengdu 610041, China Department of Microbiology & Infectious Disease Center School of Basic Medical Sciences Peking University Health Science Center Beijing China Institute of Animal Nutrition Sichuan Agricultural University Chengdu China; Key Laboratory for Animal Disease‐Resistance Nutrition of China Ministry of Education Chengdu China School of Computer Science and Engineering Nanjing University of Science and Technology Nanjing China School of Health, Fujian Medical University, Fuzhou, China Center of Clinical Laboratory, Dushu Lake Hospital Affiliated to Soochow University, Soochow University, Suzhou, Jiangsu 215000, P.R. China Rice Research Institute, Key Laboratory of Application and Safety Control of Genetically Modified Crops, Academy of Agricultural Sciences, Southwest University, Chongqing, China Affliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; Department of Pharmacology and Toxicology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China Jiangsu Province Key Laboratory of Anesthesiology Xuzhou Medical College Xuzhou China Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, 100700 Beijing, China; International Design Institute, Zhejiang University, Hangzhou, China Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China Department of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China (mainland) Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu 610041, China MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China Department of physics, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon 999077, Hongkong, China College of Materials Science & Optoelectronic Technology, University of the Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100049, China Reproductive Medicine Center The Affiliated Hospital of Youjiang Medical University for Nationalities Baise China Department of Traditional Chinese Medicine, Third Xiangya Hospital, Central South University, Changsha. MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage; School of Chemistry and Chemical Engineering; Harbin Institute of Technology; Harbin; P. R. China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China Email: [email protected]. The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi, China Department of Oral and Maxillofacial Surgery, School of Medicine, Ehime University, Shitsukawa, Toon, Ehime 791-0295, Japan. Department of Neurosurgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province 430014, China School of Physics, Hefei University of Technology, Hefei 230009, Anhui, China Ophthalmic Laboratories & Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, PR China. School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. XiangYa School of Public Health, Central South University, Changsha, China Department of Biomedical Engineering School of Big Health and Intelligent Engineering Chengdu Medical College Chengdu Sichuan 610500 P. R. China Schools of Medicine and Nursing Sciences Huzhou University Huzhou China State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China. [email protected] College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, Jiangsu, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, Jiangsu, China Hubei Key Laboratory of Ecological Restoration for River – Lakes and Algal Utilization, Hubei University of Technology, Wuhan, People’s Republic of China Department of Epidemiology and Health Statistics, Public Health School, Guangdong Pharmaceutical University, Guangzhou, China College of Life Sciences; Nankai University; Tianjin 300071; China Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, Lawson Health Research Institute, London, ON N6A 5C1, Canada. College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, Lexington, KY 40536;; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536 Department of Chemistry and Tianjin Key Laboratory of Molecular Optoelectronic Science; Tianjin University; Tianjin 300072; China Soochow University, College of Mechanical and Electrical Engineering, Robotics and Microsystems Center, Suzhou, China State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University Changchun 130012 P.R. China Cancer Metastasis Alert and Prevention Center, and Pharmaceutical Photocatalysis of State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, China State Key Laboratory for Marine Environmental Science, Institute of Marine Microbes and Ecospheres, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China; Fujian Key Laboratory of Marine Carbon Sequestration, Xiamen University, Xiamen, China Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, People's Republic of China; and; Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, People's Republic of China. School of Pharmaceutical Sciences and Institute of Materia Medica Shandong First Medical University and Shandong Academy of Medical Sciences Jinan Shandong People's Republic of China Key Laboratory of Bone Marrow Stem Cell, Jiangsu Province, Xuzhou 221002, China Camphor Engineering and Technology Research Centre of National Forestry and Grassland Administration, Jiangxi Academy of Forestry, Nanchang 330032, China NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing, China Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University, Ministry of Education, Guiyang 55004, Guizhou, China; Key Laboratory of Medical Molecular Biology, Guizhou Medical University, Guiyang 55004, Guizhou, China Department of Laboratory Medicine, General Hospital of Jinan Military Command Region, Jinan, Shandong, China (mainland) Key Laboratory of Advanced Display and System Applications of Ministry of Education, Shanghai University, 149 Yanchang Road, Shanghai 200072, P. R. China Institute of Optoelectronics, Laboratory of Materials for Information Storage and Display, Northern Jiaotong University, Beijing 100044, China. Department of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, People’s Republic of China Ludong University, China Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029; Department of Otorhinolaryngology, Department of Otolaryngology, Bengbu Third People's Hospital Affiliated to Bengbu Medical College, Bengbu, China; School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China (UESTC), Chengdu, Sichuan 610054, China Department of Clinical Laboratory, Guangzhou Women & Children Medical Center, Guangzhou Medical University, Guangdong, China (S.L., R.-C.H., Y.S., K.-L.Z., M.-L.T., T.Z., M.J., X.-H.D., J.W., Y.-W.H.). College of Food Science and Quality Engineering, Nanning University, Nanning, Guangxi 530200, P.R. China School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei 230009, China Save Sight Institute University of Sydney Sydney New South Wales Australia Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, School of Medicine Shanghai Jiao Tong University Shanghai China State Key laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Department of Orthopedic Surgery, The First Affiliated Hospital, School of Medicine, Shihezi University Shihezi 832002, Xinjiang, P. R. China. Department of Plant Pathology, College of Plant Protection Nanjing Agricultural University, and Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education Nanjing 210095 China Key Laboratory of Application and Safety Control of Genetically Modified Crops Southwest University, Rice Research Institute Chongqing 400715 People's Republic of China Anhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life Sciences, Anhui Normal University, Wuhu, 241000 Anhui, China Department of Pharmacy, West China Hospital, Sichuan University, Chengdu 610041, China Nanocluster Laboratory, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China Department of Orthopaedic Surgery; Affiliated Shanxi Provincial People's Hospital; Shanxi Medical University; Taiyuan Shanxi China Ministry of Education and Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai 200092 , China i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences Ruoshui Road Suzhou 215123 China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China; Liver Diseases Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China State Key Laboratory for Structural Chemistry of Unstable and Stable Species, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, People’s Republic of China; Beijing National Laboratory for Molecular Sciences, Beijing 100190, People’s Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Qingdao University, 308 Ningxia Road, Qingdao 266071, China; Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372 Jingsi Road, Jinan 250021, China Rice Research Institute, Key Laboratory of Application and Safety Control of Genetically Modified Crops, Academy of Agricultural Sciences, Southwest University, Chongqing 400715, China College of Chemistry and Materials Engineering; Anhui Science and Technology University; China Tianjin Institute of Urology, Second Hospital of Tianjin Medical University, Tianjin, China (mainland) School of Food and Biological Engineering, Jiangsu University, Zhenjiang, 212013, China Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences Peking University Health Science Center Beijing P.R. China Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University, Shapingba District, Chongqing 400038, China Department of Physical Education, Zhongnan University of Economics and Law, Wuhan 430073, Hubei, China Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, Mississippi, USA Division of Allergy and Immunology, Joseph Stokes, Jr., Research Institute at The Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine , People's Republic of China Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, China i-lab, Key Laboratory of multifunctional nanomaterials and smart systems Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO) Chinese Academy of Science (CAS) Suzhou 215123 P. R. China Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education East China Normal University Shanghai China; College of Physical Education and Health East China Normal University Shanghai China Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, P.R. China Department of Laboratory Medicine, Wuxi Municipal Women and Children Health Hospital, Wuxi214002, Jiangsu Province, China School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China Department of Mechanical Engineering; Tsinghua University & Key Laboratory for Advanced Materials Processing Technology, Ministry of Education of China; Beijing; China Department of Neurobiology Capital Medical University Beijing China State Key Laboratory of Ophthalmology, Retina Division, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China Institute of Engineering Thermophysics, Chinese Academy of Sciences, Beijing 100190, China; Nanjing Institute of Future Energy System, Nanjing 211135, China; Innovation Academy for Light-duty Gas Turbine, Chinese Academy of Sciences, Beijing 100190, China Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, 199 Ren Ai Road, Suzhou Industrial Park, Suzhou, Jiangsu Province, China Chinese Academy of Sciences; University of Chinese Academy of Sciences Department of Rehabilitation, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, China Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, P.R. China Key Laboratory of Preclinical Study for New Drugs of Gansu Province, and Institute of Physiology, School of Basic Medical Sciences Lanzhou University Lanzhou China State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, P. R. China; BABRI Centre, Beijing Normal University, Beijing, P. R. China School of Population Medicine and Public Health Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China Laboratory of Biomimetic Nanomaterials, Department of Orthodontics, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China Department of Chemical and Environmental Engineering and Center for Nanoscale Science and Engineering, University of California-Riverside, Riverside, California 92521, and Department of Civil and Environmental Engineering, Duke University, Durham, North Carolina 27708 School of Optoelectronic Information University of Electronic Science and Technology of China Chengdu 610054 China School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China. School of Optoelectronic Science and Engineering; University of Electronic Science and Technology of China; Chengdu; China States Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; University of Chinese Academy of Sciences, Beijing 100049, China Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China College of Information Science and Electronic Engineering, Zhejiang University , Hangzhou 310027, China [email protected] , [email protected] , [email protected] Institute of Optoelectronics Technology, Beijing Jiaotong University, Beijing 100044, China. UPMC Children’s Hospital of Pittsburgh Department of Otology and Skull Base Surgery, Eye and Ear, Nose, and Throat Hospital Fudan University Shanghai China College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu 030800, P. R. China Zhejiang Chinese Medical University Hangzhou China. College of Pharmacy Nanjing University of Chinese Medicine Nanjing China Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China Department of Chemistry, Institute of Molecular Plus, and Tianjin Key Laboratory of Molecular Optoelectronic Science Tianjin University Tianjin 300072 P. R. China Department of Clinical Laboratory The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University Wuxi Jiangsu China State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Laboratory of Special Function Materials and Structure Design of the Ministry of Education, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, Huzhou Central Hospital , Huzhou, China Shanghai Innostar Bio‐tech Co. Ltd. China State Institute of Pharmaceutical Industry Shanghai People's Republic of China Institute of Capital Pediatrics, Beijing, China Department of Prosthodontics, School of Stomatology Shandong University Jinan China; Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration Jinan China Department of Bioconvergence, Hoseo University, Asan 31499, Republic of Korea College of Chemistry and Chemical Engineering; Harbin Normal University; Harbin 150025; P. R. China College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China Department of Human Anatomy, Histology and Embryology, The Fourth Military Medical University, Xi'an - PR China State Environmental Protection Key Laboratory of Environment and Health (Taiyuan), Department of Radiological and Environmental medicine, China Institute for Radiation Protection (CIRP), Taiyuan 030001, Shanxi, China. 1Capital Institute of Pediatrics, Beijing, China Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore. Department of Gastroenterology Sichuan Academy of Science & Sichuan Provincial People’s Hospital University of Electronic Science and Technology Chengdu China Department of Thyroid Surgery The First Hospital of China Medical University 110001 Shenyang People’s Republic of China Beijing Municipal Key Laboratory of Child Development & NutriomicsThe Capital Institute of PediatricsBeijing China Clinical Laboratory, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, P.R. China Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics , Beijing 100020 , China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health Collaborative Innovation Center of Suzhou Nano Science and Technology, Southeast University Nanjing People's Republic of China 210009 State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China; Department of Chemistry, Tianjin Key Laboratory of Molecular Optoelectronic Science, Tianjin University, Tianjin 300072, China College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, P.R. China College of Chemistry and Chemical Engineering Central South University Changsha 410083 Hunan P.R. China State Key Laboratory and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China Department of Gastroenterology, The First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi 710003, P.R.�China Department of Chemistry, Tianjin Key Laboratory of Molecular Optoelectronic Science, Tianjin University, Tianjin 300072, China The University of Sydney, Save Sight Institute Discipline of Ophthalmology, Sydney Medical School, Sydney, New South Wales, Australia Beijing Municipal Key Laboratory of Child Development and Nutriomics Capital Institute of Pediatrics Beijing P.R. China Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China. b SKLLQG, Institute of Earth Environment, Chinese Academy of Sciences , Xi'an , People's Republic of China Department of Thyroid Surgery The First Hospital of China Medical University Shenyang China State Key Laboratory of Electronic Thin Films and Integrated Devices, and School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China (UESTC), Chengdu, Sichuan 610054, China College of Eco-Environmental Engineering, Guizhou Minzu University, Guiyang, Asia, China National Research Center for Environmental Analysis and Measurements(CNEAC), Beijing 100029, China. Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing 401147, China; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing 401147, China; Stomatological Hospital of Chongqing Medical University, Chongqing 401147, China Department of Hematology, Wuhan No.1 Hospital, Wuhan, China. Division of Immunogenetics (A.K., D.H.K., T.Z., S.S., S.B., S.R., H.H.D.), Rangos Research Center, Pittsburgh, Pennsylvania 15213 Key Laboratory of Petroleum Resources Research, Gansu Province, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou 730000, PR China; University of Chinese Academy of Sciences, Beijing 100049, China Department of Pathology, Fuyang People' s Hospital Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China; Hainan Sansha Provincial Observation and Research Station of Sea Turtle Ecology, Sansha, China Beijing Municipal Key Laboratory of Child Development and Nutriomics Capital Institute of Pediatrics Chaoyang District Beijing China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, Jiangsu Key Laboratory for Biomaterials and Devices, School of Public Health, Southeast University, Nanjing, China Department of Food & Nutrition, Obesity/Diabetes Center, Hoseo University, Asan, Republic of Korea University of Technology Sydney Key Laboratory of Green Chemical Engineering and Technology of College of Heilongjiang Province, College of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, P. R. China Molecular Immunity Department Capital Institute of Pediatrics Beijing China Department of Breast Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China i‐Lab Key Laboratory of Multifunctional Nanomaterials and Smart Systems Suzhou Institute of Nano‐Tech and Nano‐Bionics (SINANO) Chinese Academy of Sciences (CAS) 398 Ruoshui Road Suzhou Jiangsu 215123 P. R. China Department of Chemistry, Key Laboratory of Chemical Biology, Zhengzhou University, Zhengzhou, 450052, P.R. China, and The Key Laboratory for Bioorganic Phosphorus Chemistry, Department of Chemistry School of Life Sciences and Engineering, Tsinghua University, Beijing 100084, P.R. China Department of Orthopaedic Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China Department of Nephrology Wuhan Third Hospital Tongren Hospital of Wuhan University Wuhan China Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. Department of Microbiology and Infectious Disease Center School of Basic Medical Science Peking University Health Science Center Beijing China State Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200030 China Department of Gynecology The First Affiliated Hospital of Zhengzhou University Zhengzhou China i‐Lab, Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences Suzhou 215123 PR China Tianjin Key Laboratory of Molecular Optoelectronic Sciences Department of Chemistry School of Science Tianjin University Tianjin 300072 China i‐Lab Key Laboratory of Multifunctional Nanomaterials and Smart Systems Suzhou Institute of Nano‐Tech and Nano‐Bionics (SINANO) Chinese Academy of Sciences (CAS) 398 Ruoshui Road Suzhou Jiangsu 215123 China Department of Clinical Medicine North Sichuan Medical College Nanchong 637000 China Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, P. R. China From the Department of Pathophysiology, School of Basic Medicine (R.X., S.L., T.Z., L.Z., Q.H.); Key Laboratory of Pulmonary Diseases of Ministry of Health (R.X., S.L., T.Z., Y.L., T.W., J.Z., Y.S., L.Z., Q.H.) Ting Zhang, Li-Juan Xu, Jie Xiang, Zhi He, Zhao-Yuan Peng, Guang-Ming Huang, Guo-Zhong Ji, Fa-Ming Zhang, Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, Jiangsu Province, China. Jilin Provincial Key Laboratory of Nutrition and Functional Food, College of Food Science and Engineering, Jilin University, Changchun 130062, China Department of Bioconvergence, Hoseo University, 20 hoseoro79bun-gil, Baebang-yup, Asan 31499, Republic of Korea State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Qingdao, China; Qingdao Eye Hospital of Shandong First Medical University, Qingdao, China Department of Pathophysiology, School of Basic Medicine (L.Z., F.L., Q. Hao, T.F., Z.C., S.L., R.X., M.S., T.Z., X.F., X.Z., Q. Hu), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Pulmonary Diseases of Ministry of Health (L.Z., F.L., Q. Hao, T.F., Z.C., S.L., R.X., M.S., T.Z., X.F., X.Z., Q. Hu), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Shanghai Institute of Immunology Department of Microbiology and Immunology Shanghai Jiao Tong University School of Medicine (SJTU‐SM) Shanghai China Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and BIST Campus UAB Bellaterra 08193 Barcelona Spain Department of Physiology and Center for Inflammation, Clinical and Translational Lung Research, Lewis Katz School of Medicine at Temple University , Philadelphia, Pennsylvania , USA State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany Chinese Academy of Sciences Kunming China; University of Chinese Academy of Sciences Beijing China Department of Neurosurgery, Changzheng Hospital, Second Military Medical University, Shanghai, China School of nursing Anhui Medical University Hefei China Department of Hematology and Oncology, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200061, China Key Laboratory of Endemic and Ethnic Diseases, Guizhou Medical University, Ministry of Education, Guiyang, Guizhou 550004, P.R. China Department of Orthodontics, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, China CAS Key Laboratory of Quantum Information, University of Science and Technology of China, Hefei, Anhui 230026, China; CAS Center for Excellence and Synergetic Innovation Center in Quantum Information and Quantum Physics, University of Science and Technology of China, Hefei, Anhui 230026, China Institute of Cancer Affiliated Hospital of Jiangnan University Wuxi China Department of Ultrasound Diagnostic; Jinling Hospital; Nanjing Medical University; Nanjing 210002; P. R. China Key Lab of Nanodevices and Applications, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, P. R. China Institute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou 510405, China Research Center for Nutrition and Food Safety Institute of Military Preventive Medicine Third Military Medical University Chongqing Key Laboratory of Nutrition and Food Safety Research Center for Medical Nutrition Chongqing China Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health Southeast University and Jiangsu Key Laboratory for Biomaterials and Devices, Southeast University Nanjing 210009 China Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200135, P.R. China School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China State Key Laboratory of Natural and Biomimetic Drugs Department of Microbiology & Infectious Disease Center School of Basic Medical Sciences Peking University Health Science Center Beijing China Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China Institute of Functional Material Chemistry, Key Laboratory of Polyoxometalate Science of Ministry of Education, Faculty of Chemistry, Northeast Normal University, Ren Min Street No.5268, Changchun, Jilin 130024, PR China CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, College of Future Technology, Beijing Institute of Genomics, Chinese Academy of Sciences; China National Center for Bioinformation; University of Chinese Academy of Sciences Shanghai Institute of Materia Medica, Shanghai 200031, China. Laboratory Medicine Department, College of Medical Technology Zhejiang Chinese Medical University Hangzhou China College of Biomass Science and Engineering, Healthy Food Evaluation Research Center, Sichuan University, Chengdu 610065, China Save Sight Institute, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Harbin Medical University, Harbin, China 4State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian, China. State Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Shaanxi, Yangling 712100, China Key Laboratory of Sichuan Province for Conservation and Utilization of Fishes Resources in the Upper Reaches of the Yangtze River, College of Life Sciences, Neijiang Normal University, Neijiang 641100, China Department of Medicinal Chemistry, ‡Department of Process and Analytical Chemistry, and ¶Department of Chemistry Modeling and Informatics, Merck Research Laboratories, Merck & Co., Inc., PO Box 2000, Rahway, New Jersey 07065, United States; Department of Pharmacology and ⊥Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, Merck Research Laboratories, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States; Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism, and §Department of Pharmacology, Merck Research Laboratories, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States Department of Pharmacy, Peking University Third Hospital, Beijing 100191, China. College of Chemistry and Chemical Engineering Liaoning Normal University Dalian 116029 China Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China Inner Mongolia Key Laboratory of Molecular Pathology, Inner Mongolia Medical University NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 102629 , P.R. China School of Chemistry and Material Science; Jiangsu Normal University; Xuzhou; China Department of Rheumatology, the Second Affiliated Hospital of Zhejiang University School of Medicine State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong Province, China. Department of Gastroenterology Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi China; The Collaborative InnovAffiliated Hospital of Zunyi Medical Universityation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University Zunyi China Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210003, China State Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest Agriculture and Forestry University Henan Key Laboratory of Polyoxometalate Chemistry, Institute of Molecular and Crystal Engineering, School of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, P. R. China Key Laboratory of Aerosol Chemistry and Physics, State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710061, China; CAS Center for Excellence in Quaternary Science and Global Change, Xi’an 710061, China Department of Infection and Gastroenterology, Shanghai Children’s Hospital, SJTU School of Medicine, Shanghai 200092, China Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China Morningside Laboratory for Chemical Biology; Department of Chemistry; The University of Hong Kong; Hong Kong; P. R. China Department of Chemistry Institute of Microanalytical Systems Zhejiang University Hangzhou P. R. China Genome Institute of Singapore A‐STAR Singapore Department of Oncology, The Affiliated Hospital of Jiangnan University , No. 200, Huihe Road , Wuxi , 214000, Jiangsu , P. R. China International Laboratory for Adaptive Bio-nanotechnology (i-Lab), Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China. Department of Ultrasound, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China School of Pharmacy, Chengdu University of Traditional Chinese Medicine , Chengdu , P.R. China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, & Collaborative Innovation Center of Suzhou Nano Science and Technology Southeast University Nanjing 210009 China; Jiangsu Key Laboratory for Biomaterials and Devices Southeast University Nanjing 210009 China State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center of Excellence in Molecular Sciences, Beijing 100190, P. R. China Department of Psychology, Wannan Medical College, Wuhu, Anhui 241001, China Department of Otology and Skull Base Surgery, The First Hospital Affiliated to Xi’an Jiaotong University, Xian, PR China College of Food Science and Engineering, Ocean University of China, 5 Yushan Road, Qingdao, Shandong 266003, People’s Republic of China State Key Lab of Genetic Engineering School of Life Sciences and Institutes of Biomedical Sciences Obstetrics & Gynecology Hospital of Fudan University Shanghai China; Capital Institute of Pediatrics Beijing China College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, P.R. China Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics (SINANO) Chinese Academy of Sciences (CAS) 398 Ruoshui Road Suzhou 215123 P. R. China Cancer Research Institute, Hengyang Medical College of University of South China, Hengyang 421001, Hunan Province, China Jiyang College, Zhejiang Agriculture and Forestry University, Shaoxing 311800, China Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, East China Normal University, Shanghai, China; College of Physical Education and Health, East China Normal University, Shanghai, China Department of Pathology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia, China (mainland) 1Department of Microbiology and Infectious Disease Center, School of Basic Medical Science, Peking University Health Science Center, Beijing, P.R. China. Shanghai OE Biotech. Co., Ltd No. 138, Road of Xinjun Shanghai 201100 China Department of Surgery, Children's Hospital of Soochow University, Soochow University, Suzhou, Jiangsu 215003, P.R. China Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangdong Provincial Key Laboratory of Gastroenterology, 1838 North Guangzhou Ave, Guangzhou 510515, PR China Department of Biomedical Engineering, University of Houston, Houston, TX, USA Department of Blood Transfusion, Department of Orthopedics General Hospital of Chinese People's Liberation Army Beijing China Reality Labs Research; Redmond, WA, USA; [email protected] Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China College of Bioengineering, Jingchu University of Technology, Jingmen, Hubei, China; Hubei Engineering Research Center for Specialty Flowers Biological Breeding, Jingchu University of Technology, Jingmen, Hubei, China Department of Oncology, Jiangyin People’s Hospital, Jiangyin, Jiangsu, China Guangdong Provincial Key Laboratory of Gastroenterology Department of Gastroenterology Nanfang Hospital, Southern Medical University Guangzhou China Department of Neurology, Shanghai Jiaotong University Affiliated Sixth People’s Hospital Department of Gastroenterology endoscopy center, Affiliated Hospital of Nanjing University of Chinese Medicine Department of Biomedical Engineering, Changzhi Medical College, Changzhi, 046000. College of Life Sciences Shanghai Normal University Shanghai China Key Laboratory of Drug Targeting & Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu 610041, China Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry; Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology; West China School of Pharmacy; Sichuan University; Chengdu School of Medical Technology and Information Engineering Zhejiang Chinese Medical University Hangzhou China State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University, Nanning, Guangxi, China Gynecology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Department of Neurology The First Affiliated Hospital of Anhui Medical University Hefei China; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders Hefei China; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health Hefei China Department of Nephrology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Nephrology, Guangzhou, Guangdong, China; Guangdong-Hong Kong Joint Laboratory on Immunological and Genetic Kidney Diseases, Guangzhou, Guangdong, China; Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education); College of Chemistry and Molecular Sciences; Wuhan University; Wuhan; People's Republic of China Department of Clinical Laboratory, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China Key Laboratory of Surficial Geochemistry, Ministry of Education, School of Earth Sciences and Engineering, Nanjing University, Nanjing 210023, China; School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu 610054, China Institute of Engineering Thermophysics, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education; School of Public Health, & Collaborative Innovation Center of Suzhou Nano Science and Technology Southeast University Nanjing 210009 China; Jiangsu Key Laboratory for Biomaterials and Devices Southeast University Nanjing 210009 China Capital Institute of Pediatrics Beijing 100020 China College of Fisheries, Key Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, Huazhong Agricultural University, Wuhan, 430070, China. Fax: +86-27-87282113 Jiangxi Academy of Forestry Nanchang Jiangxi P.R. China MOE Key Laboratory of Crop Heterosis and Utilization, National Maize Improvement Center of China, College of Agronomy and Biotechnology China Agricultural University Beijing China Capital Institute of Pediatrics, Beijing, P. R. China State Key Laboratory of Animal Nutrition, Institute of Animal Science; Chinese Academy of Agricultural Sciences; Beijing China Department of Hematology and Oncology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200062, P.R. China States Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, People’s Republic of China; University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China Department of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, Fujian, China MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China; Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China Department of Gastroenterology, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China a The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing, 100050, China University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin Department of Central Laboratory Jiangyin People's Hospital Affiliated to Nantong University Jiangyin Wuxi China State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People’s Republic of China; University of the Chinese Academy of Sciences, Beijing, People’s Republic of China Jiangsu Key Laboratory of Marine Bioresources and Environment, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, Jiangsu Ocean University, Lianyungang 222005, China; Jiangsu Key Laboratory of Marine Biotechnology, School of Marine Science and Fisheries, Jiangsu Ocean University, Lianyungang 222005, China Nanjing Agricultural University, 70578, College of Agronomy, Nanjing, Jiangsu, China; College of Mechanical Engineering, Shanghai University of Engineering Science, Shanghai 200030, China Key Laboratory of Environmental Medicine Engineering of Ministry of Education, School of Public Health Southeast University Nanjing Jiangsu China The Key Laboratory of Endemic and Ethnic Diseases of the Ministry of Education of PR China (Guizhou Medical University), Guiyang, Guizhou Province, China State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, P.R. China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, P.R. China; BABRI Centre, Beijing Normal University, Beijing, P.R. China State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, No. 1954, Huashan Road, Shanghai 200030, China Food & Nutrition, Obesity/Diabetes Center, Hoseo University, Asan 336-795, Korea Division of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115;; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115; College of Life Sciences and The State Key Laboratory of Medicinal Chemical Biology Nankai University Tianjin 300071 P. R. China School of Life Science, Ludong University, Yantai, Shandong, China Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, China Department of Nephrology, Jinhua Hospital of Traditional Chinese Medicine, Jinhua, Zhejiang 321017, P.R.�China Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, and BIST, Campus UAB, Bellaterra, 08193 Barcelona, Spain School of Chemistry and Chemical Engineering, TKL of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, China Department of Pharmaceutical Analysis and Analytical Chemistry (Research Center for Innovative Technology of Pharmaceutical Analysis), College of Pharmacy, Harbin Medical University, 157 Baojian Road, Harbin, Heilongjiang Province 150081, P.R. China Chongqing Key Laboratory of Nutrition and Food Safety Research Center for Nutrition and Food Safety, Institute of Military Preventive Medicine Third Military Medical University Chongqing P. R. China State Key Laboratory of Transducer Technology Aerospace Information Research Institute of Chinese Academy of Sciences Beijing China; School of Future Technology University of Chinese Academy of Sciences Beijing China Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education, Northeast Normal University, Changchun, 130024, China Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China Shanghai Key Laboratory of Regulatory Biology, The Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai 200241, China Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States Key Laboratory of Environmental Medicine and Engineering; Ministry of Education; School of Public Health; & Collaborative Innovation Center of Suzhou Nano Science and Technology; Southeast University Division of Pediatric Endocrinology Department of Pediatrics University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193 Barcelona, Spain Dongying People's Hospital of Shandong; China Clinical Laboratory The First Affiliated Hospital of Chengdu Medical College Chengdu China Rice Research Institute, Key Laboratory of Application and Safety Control of Genetically Modified Crops, Academy of Agricultural Sciences, Southwest University Green Catalysis Center, College of Chemistry, Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou 450051, China Center for Computational and Integrative Biology Rutgers University—Camden 315 Penn Street, Science Building Camden NJ 08102 USA; Department of Chemistry Rutgers University—Camden 315 Penn Street Camden NJ 08102 USA Key Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University Wenzhou Zhejiang 325035 China Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Rockville, Maryland, USA Department of Pathology, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China. School of Physics, Hefei University of Technology , Hefei, Anhui 230009, China Institute for Personalized Medicine, State Key Laboratory of Oncogenes and Related Genes, School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Department of Gastroenterology, Hepatology, and Nutrition Shanghai Children's Hospital Precision Medicine Research Center Huaxi MR Research Center (HMRRC) Frontiers Science Center for Disease‐Related Molecular Network National Clinical Research Center for Geriatrics Department of Respiratory Medicine and Department of Radiology State Key Laboratory of Biotherapy West China Hospital Sichuan University Chengdu 610041 China Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu Province 215123, China Division of Nanobiomedicine and ‡i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, P. R. China i‐Lab, Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences Suzhou 215123 P. R. China Institute of Drug Synthesis and Pharmaceutical Process; School of Pharmaceutical Sciences; Sun Yat-sen University; Guangzhou 510006; China College of Bioinformatics Science and Technology; Harbin Medical University; Harbin, China Department of Ophthalmology & Visual Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Institute of Marine Microbes and Ecospheres, Xiamen University (Xiang'an), Xiamen, Fujian, China Department of Infectious Diseases, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China. Department of Nutrition and Food Hygiene; School of Public Health; Peking University; Beijing; PR China Plant Germplasm and Genomics Center, Germplasm Bank of Wild Species, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China MOH Key Laboratory of Systems Biology of Pathogen, Institute of Pathogen Biology, China Academy of Medical Sciences & Peking Union Medical College, 6 Rong Jing Dong Jie, Beijing 100176, China 12250,Division of Gastroenterology and Hepatology,Department of Medicine,Indiana University School of Medicine,Indianapolis,IN,USA Department of Chemistry and Tianjin Key Laboratory of Molecular Optoelectronic Science, Tianjin University, Tianjin 300072, China Institute of Microanalytical Systems, Zhejiang University, Hangzhou, 310058, China School of Medicine and Graduate School,University of Maryland, Baltimore, and University of Maryland, College Park Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, P.R. China College of Horticulture, South China Agricultural University, Guangzhou 510642, China Department of Infectious Diseases, School of Population Medicine and Public Health, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China National Key Laboratory of Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, China CDC, Beijing 102206, China Division of Pediatric Endocrinology (T.Z., D.H.K., S.L., Z.G., R.M., V.C.-N., J.Y., H.H.D.), Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224 Nephrology Department, Zhejiang Hospital, Hangzhou 310012, China State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China; University of Chinese Academy of Sciences, Beijing 100049, China Laboratory of Nutrition and Functional Food Jilin Univ. Changchun PR China Department of Surgery, Children's Hospital of Soochow University, Soochow University, Suzhou, Jiangsu, China. Department of Orthopedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang 050000, China Department of Chemistry, Stanford University, Stanford, California 94305-5080 MOE Key Laboratory of Molecular Biophysics, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China Capital Institute of Pediatrics, Beijing, China. Provincial Measles/Rubella Laboratory, Hubei Provincial Center for Disease Control and Prevention , Wuhan , China School of Computer Science and Technology, Xi’an University of Posts and Telecommunications, Xi’an, Shaanxi 710121, PR China Chest Radiotherapy Department 1, Hubei Cancer Hospital, Wuhan, China. Department of Food and Nutrition, Obesity/Diabetes Research Center, Hoseo University, Asan 31499, Korea Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA Women’s Hospital of Jiangnan University, Wuxi 214002, China Liver Transplantation Center Beijing Friendship Hospital Capital Medical University Beijing China; Clinical Center for Pediatric Liver Transplantation Capital Medical University Beijing China; Intensive Care Unit Beijing Friendship Hospital Capital Medical University Beijing China Laboratory of Entomology and Nematology, College of Plant Protection, China Agricultural University, Yuan Ming-yuan West Road #2, Beijing, China Department of Spleen and Stomach Diseases, Nanjing Jiangning Hospital of Traditional Chinese Medicine, Nanjing, China SKLLQG, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an,People’s Republic of China; Key Laboratory of Aerosol Chemistry and Physics, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an, People’s Republic of China National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant Sciences Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai China Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, Naval Medical University, Shanghai, China Department of Orthopedics (Minimally Invasive Spine Surgery), The Affiliated People's Hospital of Shanxi Medical University, Taiyuan, Shanxi 030012, P.R. China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, Jiangsu Key Laboratory for Biomaterials and Devices School of Public Health, Southeast University No.87 Dingjiaqiao Nanjing 210009 China Clinical Laboratory The First Affiliated Hospital of Chengdu Medical College Chengdu Sichuan China School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, China. Key Laboratory of Environmental Medicine and Engineering Ministry of Education Jiangsu Key Laboratory for Biomaterials and Devices School of Public Health Southeast University No. 87 Dingjiaqiao Nanjing 210009 China College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China; Key Laboratory of Food Science and Biotechnology of Hunan Province, Changsha 410128, China Department of Pharmacutical Analysis, School of Pharmacy; Xi'an Jiaotong University; Xi'an Shaanxi P.R. China Third Military Medical University; Nutrition; No 30, Gaotanyan Street Chongqing Chongqing China 400038 West China School of Medicine Sichuan University Chengdu Sichuan China School of Electrical and Electronic Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200040, China Department of Haematology and Institute of Haematology, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, P. R. China Municipal Key Laboratory of Child Development and Nutriomics Capital Institute of Pediatrics Beijing China Department of Gastroenterology, Zhejiang University School of Medicine, Hangzhou, China. Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China. Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China. State Key Laboratory of Superhard Materials Synergetic Extreme Condition High‐Pressure Science Center College of Physics Jilin University 130012 Changchun China State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People’s Republic of China *Institute of Immunology, School of Medicine, Zhejiang University, Hangzhou 310058, China; and State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China Institute of Functional Nano & Soft Materials (FUNSOM); Jiangsu Key Laboratory for Carbon-based Functional Materials & Devices; Collaborative Innovation Centre of Suzhou Nano Science and Technology; Soochow University; Suzhou Department of Center Laboratory, The Affiliated Jiangyin Hospital of Nantong University, Jiangyin, Jiangsu 214400, P.R. China Capital Institute of Pediatrics Jiangxi Academy of Forestry Camphor Engineering Technology Research Center for National Forestry and Grassland Administration 30032 Nanchang China School of Chemistry and Material Engineering Anhui Science and Technology University 233100 Fengyang Anhui China Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China Chongqing Medical University Affiliated Children’s Hospital, Chongqing, China Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA Department of Rheumatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China (mainland) Soochow University College of Food Science and Engineering, Ocean University of China Tianjin Institute of Medical and Pharmaceutical Sciences Tianjin 300020 China Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, 199 Ren Ai Road, Suzhou Industrial Park, Suzhou, Jiangsu Province 215123, China College of Chemistry and Chemical Engineering; Harbin Normal University; Harbin; P. R. China Department of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, PR China Beijing Municipal Key Laboratory of Child Development and Nutriomics; Capital Institute of Pediatrics; Beijing China Department of Neurobiology, Center of Parkinson Disease Beijing Institute for Brain Disorders, Beijing Key Laboratory on Parkinson Disease, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing Key Laboratory of Neural Regeneration and Repair Capital Medical University Beijing China Shanghai Children's Hospital, Shanghai, China Department of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Fourth Military Medical University, Xi’an, China State Key Laboratory of Reproductive Medicine; Nanjing Medical University; Nanjing; China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing; Wuhan University of Technology; Wuhan 430070; China State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China Department of Respiratory Medicine Shenzhen People's Hospital Shenzhen China Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province & Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, Guizhou Medical University, Guiyang, Guizhou, China School of Civil Engineering and Architecture East China Jiaotong University Nanchang China State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China Department of Clinical Medicine Center, The First People’s Hospital of Wenling, The Affiliated Wenling Hospital of Wenzhou Medical University, Wenling, Zhejiang 317500, China School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China Department of Neurology MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China Department of Gynecology and Obstetrics the First Affiliated Hospital of Xi'an Jiaotong University No. 277, Yanta West Road Xi'an City 710061 Shaanxi Province China School of Humanities and Social Sciences, Xi’an Jiaotong University, Xi’an; College of Tourism & Landscape Architecture, Guilin University of Technology, Guilin School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China State Key Laboratory for Structural Chemistry of Unstable and Stable Species, CAS Research/Education Center of Excellence in Molecular Sciences, Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P.R. China; Beijing National Laboratory for Molecular Sciences Beijing 100190 P.R. China; University of Chinese Academy of Sciences Beijing 100049 P.R. China Department of Spinal Minimally Invasive Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China (mainland) Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China School of Preclinical Medicine, Guangxi Medical University, Nanning, Guangxi, China Chengdu Anticancer Bioscience, Chengdu 610000, China; J. Michael Bishop Institute of Cancer Research, Chengdu 610000, China State Key Laboratory of Fine Chemicals, PSU-DUT Joint Center for Energy Research, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, P. R. China School of Chemistry and Materials Science Ludong University Yantai 264025 China Department of Neurology & Institute of Neurology, Ruijin Hospital affiliated with the Medical School of Shanghai Jiaotong University, Shanghai, China Department of Cardiology The First Affiliated Hospital of Nanjing Medical University Nanjing China College of Chinese Material Medica, Yunnan University of Chinese Medicine, Kunming, Yunnan, China; Medicine Yunnan Provincial Key Laboratory of Molecular Biology for Sino Medicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei 230026, China; Division of Advanced Nanomaterials, Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences (CAS), Suzhou 215123, China Kiangnan Stem Cell Institute Hangzhou China Ministry of Education Key Laboratory for Ecology of Tropical Islands, College of Life Sciences Hainan Normal University Haikou China Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai 200237, China Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; School of Chemical Engineering and Technology, Xinjiang University, Urumqi 830046, China Duke-NUS Graduate Medical School, Singapore College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311400, China Department of Chemistry and Centre for Atomic Engineering of Advanced Materials, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei 230601, P. R. China; Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei 230601, P. R. China 1Faculty of Health Sciences, University of Macau, Macau, China. Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province Second Affiliated Hospital, Zhejiang University Hangzhou China; Cancer Center Zhejiang University Hangzhou China; Department of Radiation Oncology Second Affiliated Hospital Zhejiang University Hangzhou China Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, People’s Republic of China Division of Nephrology, State Key Laboratory of Organ Failure Research, National Clinical Research Center for Kidney Disease, Guangdong Provincial Institute of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China. Infinitus (China) Company Ltd Guangzhou China Department of Chemistry and Center for Computational and Integrative Biology Rutgers University‐Camden 315 Penn Street Camden NJ 08102 USA School of Life Sciences and Biotechnology, Shanghai Jiaotong University, Shanghai, China Department of Rheumatology The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China Department of Gastroenterology, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China School of Chemistry and Chemical Engineering; Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion; Tianjin Key Laboratory of Drug Targeting and Bioimaging; Tianjin University of Technology; Tianjin Innovative Center of Molecular Genetics and Evolution School of Life Sciences, Guangzhou University Guangzhou 510006 China School of Environmental Science and Engineering, Shanghai Jiao Tong University, 800 Dongchuan Rd., Shanghai 200240, China Jiangsu Provincial Research Center for Animal Transgenesis and Biopharming College of Veterinary Medicine Yangzhou University Yangzhou China Center of Basic Medical Research, Institute of Medical Innovation and Research , Peking University Third Hospital , Beijing , China; Biobank, Peking University Third Hospital , Beijing , China Medical Technology College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. Laboratory of Biomimetic Nanomaterials Department of Orthodontics Peking University School and Hospital of Stomatology National Engineering Laboratory for Digital and Material Technology of Stomatology Beijing Key Laboratory of Digital Stomatology Beijing 100081 China State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences; Beijing 100190; China; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center of Excellence in Molecular Sciences; Beijing 100190 Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou 571158, China; Hainan Sansha Provincial Observation and Research Station of Sea Turtle Ecology, Sansha 573100, China Division of Immunogenetics, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224 Schools of Medicine and Nursing Sciences, Huzhou University, Huzhou, Zhejiang, 313000, China. [email protected]. Department of Gynecology and Obstetrics the First Affiliated Hospital Xi'an Jiaotong University Xi'an City China Research Center for Child Health, Department of Child Health Care, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, China Laboratory Medicine Department College of Medical Technology, Zhejiang Chinese Medical University Hangzhou China Nano-Bionics Division and i -Lab; Suzhou Institute of Nano-Tech and Nano-Bionics; Chinese Academy of Sciences; Suzhou 215123 P. R. China Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China Department of Gynecology, Affiliated Hospital of Jiangnan University, Wuxi 214062, China; Wuxi Medical College, Jiangnan University, Wuxi 214000, China Capital Institute of Pediatrics, Beijing, China the State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China; and Institute of Microanalytical Systems, Zhejiang University, Hangzhou, 310028 China, and Department of Optical Engineering, Zhejiang University, Hangzhou, 310027 China 1State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian, China. Department of Anatomy, histology and embryology, K. K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, 710032, China Tongji University, China College of Medical Technology Zhejiang Chinese Medical University Hangzhou China Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization Nanjing University of Chinese Medicine Nanjing China Biomanufacturing Center Department of Mechanical Engineering Tsinghua University Beijing 100084 P. R. China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing Beijing 100084 P. R. China; Biomanufacturing and Engineering Living Systems Innovation International Talents Base (111 Base) Beijing 100084 P. R. China Department of Chemistry Rutgers University‐Camden Camden NJ USA Department of Food and Nutrition, Obesity/Diabetes Research Center, Hoseo University Department of Radiation Oncology Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang China State Key Lab of Supramolecular Structure and Materials; College of Chemistry; Jilin University; Changchun; China Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, and Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Xining, Qinghai 810008, People’s Republic of China Department of Pathology,Medical college,Huzhou University,Huzhou,Zhejiang 313000,China. Department of Radiation Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University , Hangzhou, China; Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University , Hangzhou, China; Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education), Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University , Hangzhou, China Department of Orthopedics, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi Province, China Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences; Peking University Health Science Center; Beijing China Huzhou Key Laboratory of Precise Prevention and Control of Major Chronic Diseases, Huzhou University, Huzhou, Zhejiang, P.R. China Department of Cellular Biology and Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602 School of Environmental Science and Engineering, Suzhou University of Science and Technology, Suzhou 215009, China. Department of Pathophysiology, Dalian Medical University, Dalian, Liaoning 116044, P.R. China School of Population Medicine and Public Health,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing, China Division of Engineering in Medicine Brigham and Women's Hospital Department of Medicine Harvard Medical School Cambridge MA 02139 USA; Harvard‐MIT Division of Health Sciences and Technology Massachusetts Institute of Technology Cambridge MA 02139 USA; Department of Mechanical Engineering Tsinghua University Beijing 100084 China Division of Infectious Diseases, Children’s Hospital of Shanghai Jiaotong University, Shanghai 200240, China Chongqing Key Laboratory of Nutrition and Food Safety, Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine Third Military Medical University Chongqing, 400038 People's Republic of China Department of Food and Nutrition, Institute of Basic Science, Obesity/Diabetes Research Center, Hoseo University, Asan, South Korea. Department of Computing The Hong Kong Polytechnic University 11 Yuk Choi Road, Hung Hom, KLN Hong Kong 999077 China Tianjin Institute of Medical and Pharmaceutical Sciences, Tianjin, China Department of Food and Nutrition, College of Life and Health Sciences, Hoseo University, Chungnam, Korea School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China Shanghai Jiaotong University, China Department of Respiratory Medicine, Kunming Children’s Hospital , China *Department of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University; Department of Diabetes and Endocrinology Affiliated Hospital of Southwest Medical University Luzhou China Institute of Molecular Science Shanxi University 030006 Taiyuan China Office of Product Evaluation and Quality Food and Drug Administration, Center for Devices and Radiological Health Silver Spring Maryland USA Department of Food Science Louisiana State University Agricultural Center 70803 Baton Rouge Louisiana Key Laboratory of Xinjiang Coal Clean Conversion and Chemical Process, College of Chemistry and Chemical Engineering, Xinjiang University, 14 Sheng Li Road, Urumqi 830046, P. R. China; College of Chemistry and Materials Science, Jinan University, No. 601 Huangpu Avenue West, Tianhe District, Guangzhou 510632, P. R. China; Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, No. 2 Nengyuan Road, Wushan, Tianhe District, Guangzhou 510640, P. R. China Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, China College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, China; University Hospital, Zhejiang Normal University, Jinhua, China Department of Obstetrics and Gynecology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huaiyin, Huai'an, Jiangsu 223300, P.R. China Luzhou Key Laboratory of Cardiovascular and Metabolic Diseases Affiliated Hospital of Southwest Medical University Luzhou China School of Physics, State Key Laboratory of Crystal Materials, Shandong University; Jinan; China Department of Oncology, The Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China. State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology (IPB), Chinese Academy Medical Sciences (CAMS) & Peking Union Medical College (PUMC), Beijing 100176, China National Laboratory of Solid State Microstructures/School of Electronics Science and Engineering, Nanjing University, 210093 Nanjing, China Department of Orthopedics, Second Affiliated Hospital of Xi'an Jiaotong University, Xi’an, Shaanxi Province, 710004, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China Department of Prosthodontics School and Hospital of Stomatology Cheeloo College of Medicine Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration Jinan China College of Physical Education & Health East China Normal University Shanghai China School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu; Department of Nursing, Sichuan Vocational College of Health and Rehabilitation, Zigong Department of Rheumatology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310009, China Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences Peking University Beijing China State Key Laboratory for Conservation and Utilization of Subtropical Agro‐bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology Guangxi University Nanning People’s Republic of China Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China School of Chemical Engineering; Northwest University; Xi'an 710069; P. R. China College of Biological Sciences and Technology Beijing Forestry University Beijing 100083 China; National Engineering Laboratory for Tree Breeding Beijing Forestry University Beijing 100083 China School of Chinese Materia Medica Beijing University of Chinese Medicine Beijing P. R. China Tianjin Normal University Department of Pharmacy, Xiangya Hospital of Central South University, Changsha 410008, China. Ministry of Education and Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Institute of Cancer, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China Department of Pharmacy, Wuxi Maternal and Child Health Hospital, Wuxi, Jiangsu Province, China Wuxi Hospital for Maternal and Child Health Care Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, China Beijing Municipal Key Laboratory of Child Development and NutriomicsCapital Institute of Pediatrics Beijing China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong Province, China Department of Epidemiology and Health Statistics Guangdong Pharmaceutical University Guangzhou China State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130012, P. R. China School of Food Science and Technology, Key Laboratory of Food Science and Safety, Ministry of Education Southern Yangtze University 170 Huihe Road Wuxi Jiangsu Province 214036 People’s Republic of China Agriculture College, Yanbian University, Yanji 133002, China *Division of Gastroenterology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205; Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning, China (mainland) Laboratory of Nonhuman Primate Disease Modeling Research, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China Department of Otorhinolaryngology‑Head and Neck Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061 P.R. China Department of Imaging,Tianjin Huanhu Hospital,Tianjin,300350,China. Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess Beijing University of Chemical Technology Beijing 100029 P. R. China i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences (CAS) Suzhou 215123 China Xiamen University 2 Softmatter Laboratory, Department of Physics and ITPA, , Xiamen 361005, People’s Republic of China Department of Orthopedic Surgery The Fifth Affiliated Hospital of Shanxi Medical University Taiyuan Shanxi China Liver Diseases Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China (mainland) Save Sight Institute The University of Sydney Sydney New South Wales Australia Department of Biomedical Engineering , University of Houston , Houston , TX , 77204 , United States of America Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu 221000, P.R. China Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China Department of Pediatrics, West China Second University Hospital, Sichuan University Chengdu, P. R. China. Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University Chengdu, P. R. China. Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Institute of Physiology, School of Basic Medical Sciences Lanzhou University Lanzhou China Department of Gastroenterology and Endoscopy, The Third Affiliated Hospital of Naval Medical University, Shanghai, China Stomatological Hospital of Chongqing Medical University, Yubei District, Chongqing, China; Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Chongqing, China; Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education, Chongqing, China NMR Structure Elucidation, Process Research and Development and ‡Discovery Chemistry, MRL, Merck & Co., Inc., P.O. Box 2000, Rahway, New Jersey 07065, United States; Department of Chemistry and Biochemistry and ∥Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive MC-0358, La Jolla, California 92093, United States i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics (SINANO) Chinese Academy of Sciences (CAS) 398 Ruoshui Road Suzhou 215123 P. R. China Department of Otorhinolaryngology-Head and Neck Surgery, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China Department of Pharmacy, Shandong Rehabilitation Hospital College of Chemistry and Chemical Engineering; Harbin Normal University; Harbin 150025; China Department of Orthopaedics, Ningbo Medical Center, Lihuili Hospital, Ningbo, 315000, China;; Jilin Provincial Key Laboratory of Nutrition and Functional Food, College of Food Science and Engineering, Jilin University, Changchun 130062, People's Republic of China State Key Laboratory of Fine Chemicals School of Chemical Engineering Dalian University of Technology Dalian 116024 P. R. China State Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Shaanxi, Yangling 712100, China; Key Laboratory of Biology and Genetics Improvement of Maize in Arid Area of Northwest Region, Ministry of Agriculture, Northwest A&F University, Shaanxi, Yangling 712100, China Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University Department of Food and Nutrition, Obesity/Diabetes Center, Hoseo University, Asan, Chungcheong 336‑795, Republic of Korea Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University National Clinical Research Center for Cardiovascular Diseases, Beijing, China Cardiovascular Department, Guangdong No.2 Provincial People's Hospital, Guangdong 510317, China Tianjin Institute of Medical & Pharmaceutical Sciences Tianjin 300020 China State Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Yangling, China. Key Laboratory of Biology and Genetics Improvement of Maize in Arid Area of Northwest Region, Ministry of Agriculture, Northwest A&F University, Yangling, China. Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China; Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology; School of Physics Science and Engineering; Tongji University; Shanghai 200092; China Department of Assisted Reproduction, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai, China. Department of Surgery, Children’s Hospital of Soochow University, Soochow University, Suzhou, Jiangsu 215000, China College of Veterinary Medicine/Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, Jiangsu 225009, China State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University, Nanning, China College of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan 610500, P.R. China Department of Chemistry; Rutgers University – Camden; Camden; USA Regend Therapeutics Co. Ltd Zhejiang China a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine , Ministry of Education & Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing, 100050, China Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore Department of Cardiology Beijing Anzhen Hospital Capital Medical University National Clinical Research Centre for Cardiovascular Diseases Beijing 100029 China Laboratory of Biomimetic Nanomaterials, Department of Orthodontics, Peking University School and Hospital of Stomatology , Beijing , PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology , Beijing , PR China; Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology , Beijing , PR China State Key Laboratory of Cellular Stress Biology Innovation Center for Cell Signaling Network School of Life Sciences Xiamen University Xiamen China Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, Massachusetts, USA; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA State Key laboratory of Environmental Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China State Key Laboratory of Plant Physiology and Biochemistry College of Biological Sciences China Agricultural University Beijing 100193 China Institute for Translational Medicine, Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266003, China; School of Stomatology, Qingdao University, Qingdao 266003, China School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China Department of Thyroid Surgery The First Hospital of China Medical University Shenyang Liaoning Province China Department of Infectious Diseases, The Third People’s Hospital, Changzhou, Jiangsu Province, China Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China; National Clinical Research Center for Eye Diseases, Shanghai, China; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China Biomanufacturing Center Department of Mechanical Engineering Tsinghua University Beijing 100084 P. R. China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing Beijing 100084 P. R. China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base) Beijing 100084 P. R. China Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China State Key Laboratory of Organ Failure Research Guangdong Provincial Key Laboratory of Gastroenterology Department of Gastroenterology Nanfang Hospital Southern Medical University Guangzhou Guangdong China Department of Gynaecology, Zibo Central Hospital, No. 54 Gongqingtuan Road, Zhangdian District, Zibo 255036, Shandong, China Department of Microbiology & Infectious Disease Center School of Basic Medical Sciences Peking University Health Science Center Beijing P.R. China State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P.R. China; Beijing National Laboratory for Molecular Sciences CAS Research/ Education Center of Excellence in Molecular Sciences Beijing 100190 P.R. China; University of Chinese Academy of Sciences Beijing 100049 P.R. China Catalan Institute of Nanoscience and Nanotechnology (ICN2) Campus UAB Bellaterra 08193 Barcelona Spain Schools of Medicine and Nursing Sciences, Huzhou University, Huzhou, Zhejiang 313000, P.R. China School of Physics; State Key Laboratory of Crystal Materials; Shandong University; Jinan 250100; China Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education The First Hospital Institute of Immunology Jilin University Changchun China; National‐local Joint Engineering Laboratory of Animal Models for Human Diseases Changchun China State Key Laboratory of Chemical Resource Engineering, Key Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education) and Laboratory of Biomedical Materials, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China State Key Laboratory of Applied Organic Chemistry; Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province; Laboratory of Special Function Materials and Structure Design of the Ministry of Education; College of Chemistry and Chemical Engineering; Lanzhou University College of Food Science and Engineering, Jilin University, Changchun, Jilin 130062, People’s Republic of China Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China R&D Center, Shanghai Hengrui Pharmaceutical Co., LTD., 279 Wenjing Road, Shanghai 200245, China School of Ophthalmology & Optometry, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China Department of Pharmacology and Toxicology Shanghai Institute of Planned Parenthood Research 2140 Xie Tu Road Shanghai 200032 People's Republic of China School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Institute of pharmaceutical and medical devices supervision, National Medical Products Administration-Chinese Academy of Medical Sciences, Beijing, China Department of Clinical Medicine, North Sichuan Medical College, Nanchong, P. R. China Department of Mechanical Engineering, Biomanufacturing Center Tsinghua University Beijing China Institute of Soil and Water Conservation Chinese Academy of Sciences and Ministry of Water Resources Yangling China State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University , Shanghai 200241, China Regend Therapeutics Suzhou China Laboratory of Nutrition and Functional Food, Jilin University, Changchun, P.R. China; Tianjin Institute of Medical & Pharmaceutical Sciences 79 Duolun Road Tianjin 300020 China Molecular Modeling and Biopharmaceutical Center and Department of Pharmaceutical Sciences; College of Pharmacy; University of Kentucky; Lexington; USA School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China State Key Laboratory of Veterinary Etiological Biology, National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China Jiangxi Academy of Forestry Camphor Engineering and Technology Research Center of National Forestry and Grassland Administration, , Nanchang 330032, China Laboratory of Biomimetic Nanomaterials Department of Orthodontics Peking University School and Hospital of Stomatology National Engineering Laboratory for Digital and Material Technology of, Stomatology Beijing Key Laboratory of Digital Stomatology Beijing 100081 P. R. China School of Food Science and Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China Jilin Provincial Key Laboratory of Nutrition and Functional Food and College of Food Science and Engineering, Jilin University, Changchun 130062, People’s Republic of China Ministry of Education Key Laboratory of Crop Heterosis and Utilization, National Maize Improvement Center of China, College of Agronomy and Biotechnology, China Agricultural University, 100094 Beijing, China Key Laboratory of Preclinical Study for New Drugs of Gansu Province, and Institute of Physiology, School of Basic Medical Sciences, Lanzhou University, 199 Donggang West Road, Lanzhou 730000, PR China Kiangnan Stem Cell Institute, Zhejiang 311300, China Department of gynecology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou310006, P. R. China Clinical Laboratory Center The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University Wenzhou Zhejiang China School of Physics, State Key Laboratory of Crystal Materials, Shandong University, Shandanan Street 27, Jinan 250100, China Department of Microbiology & Infectious Disease Center, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100191, People’s Republic of China Department of Bacteriology, Capital Institute of Pediatrics, No. 2 Yabao Road, Beijing 100020, People's Republic of China Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China State Key Laboratory for Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College, Beling 100050, China. Department of Rehabilitation Children's Hospital of Chongqing Medical University (CHCMU) Chongqing China; National Clinical Research Center for Child Health and Disorders Chongqing China; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing China; China International Science and Technology Cooperation base of Child development and Critical Disorders Chongqing China; Chongqing Key Laboratory of Pediatrics Chongqing China Department of Hematology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, 122 Luoshi Road, Wuhan 430070, China Department of Toxicology, School of Public Health, Southeast University, Nanjing 210009, China. [email protected] Northwest Women's and Children's Hospital Xi'an 710061 P. R. China Department of Genetics and Metabolism, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310052, China. [email protected]. Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China; Institute of Hematology, Zhejiang University, Hangzhou, China; Key Laboratory of Hematologic Malignancies, Diagnosis and Treatment, Zhejiang, Hangzhou, China Department of Anesthesiology and Surgical Intensive Care Unit Xinhua Hospital School of Medicine and School of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200092 China; State Key Laboratory of Oncogenes and Related Genes Institute for Personalized Medicine School of Biomedical Engineering Shanghai Jiao Tong University Shanghai 200030 China Division of Gastroenterology and Hepatology,Department of Medicine,Indiana University School of Medicine,Indianapolis,IN Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; Biomanufacturing and Engineering Living Systems, Innovation International Talents Base (111 Base), Beijing 100084, China School of Environmental Science and Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China Shanghai Key Laboratory of Regulatory Biology Institute of Biomedical Sciences and School of Life Sciences East China Normal University Shanghai 200241 China Henan Key Laboratory of Polyoxometalate Chemistry, Institute of Molecular and Crystal Engineering, School of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, People’s Republic of China College of Materials Science and Engineering, Hunan University, Changsha, 410082, China Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China;; Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China;; Key NHC Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China; and Department of Chemical and Materials Engineering, The University of Auckland, Auckland 1010, New Zealand Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of China Institute of Medical Information & Library, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China Department of Bio-Convergence System, Hoseo University, Asan, South Korea. Department of Dermatology 1st Affiliated Hospital of Dalian Medical University Dalian City Liaoning Province China Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, Zhejiang 315201, China Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia, Fudan University, Shanghai, China; Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and BIST Campus UAB Bellaterra Barcelona 08193 Spain Department of Neurology, The Third Central Clinical College of Tianjin Medical University , Tianjin 300170 , China; Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases , Tianjin , China; Artificial Cell Engineering Technology Research Center , Tianjin , China; Tianjin Institute of Hepatobiliary Disease , Tianjin , China Regend Therapeutics, Shanghai 200127, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China; Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China Department of Pharmaceutical Analysis and Analytical Chemistry (Research Center for Innovative Technology of Pharmaceutical Analysis), College of Pharmacy, Harbin Medical University, 157 Baojian Road, Harbin 150081, Heilongjiang Province, P. R. China Key Laboratory of Environmental Medicine and Engineering, Ministry of Education; School of Public Health Southeast University Nanjing People's Republic of China Division of Allergy and Immunology, Joseph Stokes Jr. Research Institute at the Children’s Hospital of Philadelphia, Department of Pediatrics , Philadelphia Department of Neurology and Institute of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China State Key Laboratory for Mechanical Behavior of Materials Shaanxi International Research Center for Soft Matter Xi'an Jiaotong University Xi'an 710049 China Jilin Provincial Key Laboratory of Nutrition and Functional Food and College of Food Science and Engineering, Jilin University, Changchun 130062, P. R. China Henan Key Laboratory of Polyoxometalate Chemistry, School of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, P. R. China Capital Institute of Pediatrics Beijing China Department of Respiratory Medicine College of Chemistry Jilin University 2699 Qianjin street Changchun 130012 P. R. China Biomanufacturing Center Department of Mechanical Engineering Tsinghua University Beijing 100084 P. R. China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing Beijing 100084 P. R. China; Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base) Beijing 100084 P. R. China School of Automation, Harbin University of Science and Technology, Harbin, China Department of Biomedical Engineering, University of Houston, Houston, Texas, USA Qionglai Hospital of Traditional Chinese Medicine, Qionglai, Chengdu, Sichuan, China. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Materials Science, Zhejiang Normal University, Jinhua 321004, China Department of Ophthalmology, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China; National Clinical Research Center for Eye Diseases Shanghai China; Shanghai Key Laboratory of Fundus Diseases Shanghai China; Shanghai Engineering Center for Visual Science and Photomedicine Shanghai China Department of Radiation Oncology Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang P. R. China Division of Allergy & Immunology, Joseph Stokes Jr. Research Institute at The Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine School of Nursing, Anhui Medical University, No. 81 Mei Shan Road, Shu Shan District, Hefei, Anhui Province, People’s Republic of China Department of the Liver Center, Beijing Ditan Hospital, Capital Medical University, No. 8 Jingshundong Street, Chaoyang District, Beijing 100015, China Department of Gastroenterology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, China Research Center for Nutrition and Food Safety Institute of Military Preventive Medicine Third Military Medical University Chongqing P. R. China Department of Rheumatology and Immunology, Affiliated Changzhou No. 2 People’s Hospital with Nanjing Medical University, Changzhou, China Department of Orthodontics Central Laboratory National Center for Stomatology National Engineering Research Center of Oral Biomaterials and Digital Medical Devices Beijing Key Laboratory of Digital Stomatology Peking University School and Hospital of Stomatology Beijing 100081 China School of Mechanical Engineering, Tiangong University, Tianjin, China; Tianjin Key Laboratory of Modern Electromechanical Equipment Technology, Tianjin, China Division of Endocrinology and Metabolism, Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital Capital Medical University Beijing China Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116, China Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo 315832, China From the Center for Reproductive Medicine, Cheeloo College of Medicine, Key Laboratory of Reproductive Endocrinology of the Ministry of Education, and the National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Shandong Key Laboratory of Reproductive Medicine, and Shandong Provincial Clinical Research Center for Reproductive Health, Jinan (J.Y., Y.Q., H.Z., D.W., J.L., T.N., W.Z., K.W., Y.G., Y.S., Z.-J.C.), the Center for Reproductive Medicine, Ren... Guizhou Provincial Key Laboratory for Rare Animal and Economic Insect of the Mountainous Region, Guizhou Provincial Engineering Research Center for Biological Resources Protection and Efficient Utilization of the Mountainous Region, Department of Biology and Engineering of Environment, Guiyang University , Guiyang , China Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China; Co-innovation Center of Henan Province for New Drug R & D and Preclinical Safety; Institute of Drug Discovery and Development; School of Pharmaceutical Sciences, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan 450001, China College of Chemistry and Green Catalysis Center Henan Institute of Advanced Technology Zhengzhou University Zhengzhou 450001 P. R. China Science and Techonology on Thermostructural Composite Materials Laboratory, Northwestern Polytechnical University, Xi’an 710068, P. R. China Department of Anatomy and K.K. Leung Brain Research Centre, Preclinical School of Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan, Hube, China Department of Infection and Gastroenterology, Shanghai Children’s Hospital, SJTU School of Medicine, 1400 West Beijing Road, Shanghai 200040, China Shanghai Key Laboratory of Special Artificial Microstructure Materials and Technology; School of Physics Science and Engineering of Tongji University; Shanghai 200092; PR China Yunnan Key Laboratory of Primate Biomedicine Research, Institute of Primate Translational Medicine Kunming University of Science and Technology Kunming China School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical College, Zhejiang, Wenzhou 325003, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China CTL-MAT, Ohio, Cleveland, USA Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China Institute of Medical Information/Medical Library, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China Department of Biotherapy State Key Laboratory of Biotherapy, West China Hospital Sichuan University Chengdu Sichuan China; West China Hospital, West China School of Medicine Sichuan University Chengdu Sichuan China College of Information Science and Electronic Engineering, Zhejiang University , Hangzhou 310027, China Department of Operating Room Qilu Hospital of Shandong University Shandong China; Nursing Theory & Practice Innovation Research Center Shandong University Shandong China College of Chemistry and Chemical Engineering, Southwest University, Chongqing400715, P. R. China Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Center for Cancer Bioinformatics, Peking University Cancer Hospital & Institute, Beijing 100142, China National Institute of Parasitic Diseases; Chinese Center for Disease Control and Prevention; Key Laboratory of Parasite and Vector Biology of the Chinese Ministry of Health; WHO Collaborating Center for Malaria; Schistosomiasis and Filariasis School of Materials Science and Engineering; Hefei University of Technology; Hefei; P. R. China College of Pharmacy, Harbin Medical University, No. 157, Baojian Road, Nangang District, Harbin City, 150081Heilongjiang Province, China School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P.R. China Hebei Key Laboratory of Optic-electronic Information and Materials, China; College of Physics Science & Technology, Hebei University, Baoding 071002, China Food & Nutrition, Obesity/Diabetes Center, Hoseo University, Asan, South Korea Department of Thyroid SurgeryThe First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China Eye and Ear Nose Throat Hospital, Shanghai Medical School, Fudan University; Department of Ophthalmology; No. 83, Fenyang Road Shanghai China 200032 Department of Food and Nutrition, Obesity/Diabetes Research Center Hoseo University Asan South Korea State Key Laboratory of Fine Chemicals, PSU-DUT Joint Center for Energy Research and Department of Catalysis Chemistry and Technology, School of Chemical Engineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, P. R. China Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Chongqing Medical University, Chongqing 400016, China. [email protected] Shanghai OE Biotech. Co., Ltd Shanghai China Department of Thyroid Surgery The First Hospital of China Medical University Shenyang Liaoning PR China Infinitus (China) Company Ltd. Guangzhou People's Republic of China State Key Laboratory of Oral Diseases National Clinical Research Center for Oral Diseases Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management West China College of Stomatology Sichuan University Chengdu China; State Key Laboratory of Biotherapy and Cancer Center West China Hospital Collaborative Innovation Center for Biotherapy Sichuan University Chengdu China State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences Peking University Health Science Center Beijing China Community Health Service Guidance Center, Shanxi Provincial People’s Hospital College of Computer Science and Technology, Beijing University of Technology, Beijing 100124, China Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China; Institute of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China Department of Orthopedics, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China (mainland) Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China; NHC Key Laboratory of Myopia, Fudan University, Shanghai, China School of Food and Biological Engineering Jiangsu University Zhenjiang China State Key Laboratory of Chemical Engineering; School of Chemical Engineering; East China University of Science and Technology; Shanghai 200237; P.R. China Department of Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Beijing Key Laboratory of Ionic Liquids Clean Process, CAS Key Laboratory of Green Process and Engineering, State Key Laboratory of Multiphase Complex Systems, Institute of Process Engineering, Beijing, 100190, P. R. China Department of Pathophysiology, Medical College of Nanchang University, China Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, Nanjing, 211816, China Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Neonatology Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health Guangzhou China State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Hubei Hongshan Laboratory, Wuhan, China; Interdisciplinary Sciences Research Institute, Huazhong Agricultural University, Wuhan, China College of Chemistry and Materials Science, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Zhejiang Normal University, Jinhua 321004, P. R. China Department of Nursing, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat‐sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangdong Provincial Clinical Research Center for Ocular Diseases Guangzhou China i-Lab, Nano-X Vacuum Interconnected Workstation, Key Laboratory of Multifunction Nanomaterials and Smart Systems, Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences (CAS), 398 Ruoshui Road, Suzhou 215123, China Department of Neurology & Institute of Neurology, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China Key Laboratory of Advanced Pharmaceutical Technology Ministry of Education of China Co‐innovation Center of Henan Province for New Drug R & D and Preclinical Safety Institute of Drug Discovery and Development Zhengzhou University Zhengzhou Henan China School of Material Science & Engineering, Beijing Institute of Technology, Beijing 100081, China 1Department of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, Liaoning, China Department of Neurology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China Department of Health Care Dongying People's Hospital Dongying China Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, Mississippi, USA Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland. Department of Dermatology, Children’s Hospital of Soochow University, Suzhou, Jiangsu Province 215025, China Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, P.R. China Department of Breast Surgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan Province, 471003, China Laboratory of Electron Microscopy North Sichuan Medical College Nanchong 637007 People's Republic of China; Department of Histology and Embryology North Sichuan Medical College Nanchong 637007 People's Republic of China Department of Orthodontics Peking University School and Hospital of Stomatology Beijing 100081 China; National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory for Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials Beijing 100081 China Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China College of Veterinary Medicine, Yangzhou University, Yangzhou, China Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University Center for Environment and Water Resources College of Chemistry and Chemical Engineering Central South University Changsha P.R. China College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, Kunming, Yunnan 650500, P.R. China College of Chemistry and Chemical Engineering; Central South University; Changsha Hunan P.R. China Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China State Key Laboratory of Transducer Technology, Aerospace Information Research Institute, Chinese Academy of Sciences, Beijing100190, People’s Republic of China; School of Future Technology, University of Chinese Academy of Sciences, Beijing100049, People’s Republic of China Department of Pathology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China; Institute of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China Save Sight Institute, The University of Sydney, Sydney, Australia Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R.China. [email protected]. College of Physical Education and Health, East China Normal University The Capital Institute of Pediatrics, Beijing 100022, China Department of Bioconvergence, Hoseo University, Asan, Korea College of New Energy and Materials China University of Petroleum Beijing 102249 P. R. China State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China; State−Province Joint Engineering Laboratory of Targeted Drugs from Natural Products, Xiamen University, Xiamen, Fujian 361102, China Department of Microbiology, Peking University Health Science Center, Beijing, 100191, China Key Laboratory of Endemic and Ethnic Diseases of the Ministry of Education, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, Barcelona, 08193 Catalonia, Spain; Catalonia Institute for Energy Research (IREC), Jardins de les Dones de Negre 1, Sant Adrià del Besòs,Barcelona, 08930 Catalonia, Spain Consumer Testing Technology Shenzhen P. R. China Department of Anatomy Yong Loo Lin School of Medicine, National University of Singapore Singapore Department of Psychology and Beijing Key Laboratory of Behavior and Mental Health Peking University China Division of Immunogenetics Department of Pediatrics Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, China Department of Gastroenterology, Hepatology and Nutrition; Institue of Pediatric Infection, Immunity and Critical Care Medicine, Shanghai Children’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China College of Pharmacy, Harbin Medical University, Harbin, Heilongjiang 150081, P. R. China; Department of Inorganic Chemistry and Physical Chemistry, College of Pharmacy, Harbin Medical University, Heilongjiang 150081, P. R. China Key Laboratory of Modern Acoustics, Department of Physics and Collaborative Innovation Center of Advanced Microstructures, Nanjing University , Nanjing 210093, China [email protected] , [email protected] , [email protected] , [email protected] Department of Neurosurgery, The Chinese People's Liberation Army Rocket Force General Hospital, Beijing 100088, P.R. China Department of Neurosurgery, PLA Rocket Force General Hospital, Beijing, P.R. China. Purdue University, Industrial Engineering, West Lafayette, United States Department of Microbiology, Peking University Health Science Center, Beijing 100191, China. National Laboratory of Solid‐State Microstructures School of Electronics Science and Engineering Collaborative Innovation Center of Advanced Microstructures Nanjing University Nanjing 210093 P. R. China State Key Laboratory of Southwestern Chinese Medicine Resources,Chengdu University of Traditional Chinese Medicine Chengdu 611137,China. Division of Biostatistics Dalla Lana School of Public Health, University of Toronto Toronto Ontario Canada Department of Special Economic Animal Nutrition and Feed Science, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, No. 4899, Juye Street, Jingyue District, Changchun 130112, China From the Molecular Medicine Research Center, State Key Laboratory of Biotherapy (L.-j.W., L.-m.K., D.-n.W., C.T., H.Z., T.Z., G.-q.C., K.Z., W.Z.) and State Key Laboratory of Biotherapy and Cancer Center (Y.-q.W., H.-s.Y.), West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu; and Department of Intensive Care Unit of Gynecology and Obstetrics, West China Second University Hospital (F.X.) and Department of Liver Surgery, West China Hospital (H.-y.L., Y.-g.W.), Sichuan... Department of Ophthalmology and Visual Science, Eye, Ear, Nose, and Throat Hospital, Shanghai Medical School, Fudan University, Shanghai 200031, China. Institute of Functional Material Chemistry; Key Laboratory of Polyoxometalate Science of Ministry of Education; Faculty of Chemistry; Northeast Normal University; Changchun 130024 Department of Nautical Psychology Faculty of Psychology Second Military Medical University Shanghai P. R. China Beijing National Center for Electron Microscopy, Tsinghua University, Beijing 100084, China, Laboratory of Advanced Materials, Department of Materials Science and Engineering, Tsinghua University, Beijing, 100084, China, Laboratory for Advanced Materials, Department of Chemical Engineering, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China, and Department of Physics, University of York, Heslington, York YO10 5DD, U.K. i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics; Chinese Academy of Sciences; Suzhou 215123 P.R. China Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine College of Medicine and Science, Mayo Clinic MN USA General Medicine, Southwest Medical University, Luzhou, Sichuan, People's Republic of China. From the State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China; the2Institute of Neuroscience, Chinese Academy of Sciences, Shanghai, China; the Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, P.R. China Medical Center for Digestive Diseases the Second Affiliated Hospital of Nanjing Medical University Nanjing 210011 China; Key Lab of Holistic Integrative Enterology Nanjing Medical University Nanjing 210011 China Department of Cell Biology, Peking University Stem Cell Research Center, Peking University Health Science Center, School of Basic Medical Sciences, Beijing, China. Division of Nephrology, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China;; Shanghai Institute of Kidney and Dialysis, Shanghai, China;; Key Laboratory of Kidney and Blood Purification of Shanghai, Shanghai, China State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China Institute of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China; Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China for the H-REPLACE Investigators College of New Energy and Materials, China University of Petroleum, Beijing 102249, China Laboratory of Nonhuman Primate Disease Modeling Research State Key Laboratory of Biotherapy West China Hospital, Sichuan University, Guoxue Alley Wuhou District Chengdu Sichuan China Department of Pathology, The Third Affiliated Hospital of Zhengzhou University Lab of Hepatopharmacology and Ethnopharmacology, School of Pharmaceutical Sciences, South-Central Minzu University, No. 182, Minyuan Road, Wuhan 430074, China Beijing Key Laboratory of Bioprocess, Beijing University of Chemical Technology, Beijing, China Division of Functional Materials and Nanodevices, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China; Laboratory of Advanced Nano-Optoelectronic Materials and Devices, Qianwan Institute of CNITECH, Ningbo 315336, Zhejiang, China Department of Radiology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, P. R. China Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China National Clinical Research Center for Digestive Diseases Department of Gastroenterology Changhai Hospital Naval Medical University Shanghai China Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai 200080 , China; Shanghai Key Laboratory of Ocular Fundus Diseases , Shanghai 200080 , China Key Laboratory of the Three Gorges Reservoir Region’s Eco-environment, Ministry of Education, College of Environment and Ecology, Chongqing University, No.174 Shazhengjie, Shapingba, Chongqing 400044, China Department of Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; The Graduate School of Southwest Medical University, Luzhou, Sichuan 646000, China ( 610041) Neonatal Intensive Care Unit, West China Second University Hospital, Sichuan University, Chengdu 610041, China. () ( 610041) Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, Sichuan University, Chengdu 610041, China. Department of Microbiology and Infectious Disease Center; School of Basic Medical Sciences; Peking University Health Science Center; Beijing 100191; P. R. China Chongqing Key Laboratory of Nutrition and Food Safety Research Center of Nutrition and Food Safety, Institute of Military Preventive Medicine, Third Military Medical University Chongqing People's Republic of China Department of Photoelectric Band Gap Materials, Key Laboratory of Ministry of Education, College of Chemistry and Chemical Engineering, Harbin Normal University, Harbin 150025, China Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193 Barcelona, Catalonia, Spain Department of Orthodontics Peking University School and Hospital of Stomatology Beijing China; Center for Craniofacial Stem Cell Research and Regeneration Peking University School and Hospital of Stomatology Beijing China Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, P. R. China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, P. R. China; Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, P. R. China Department of Chemistry & Biochemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, United States Department of Microbiology & Infectious Disease Center School of Basic Medical Science Peking University Health Science Center Beijing China Key Laboratory of Environmental Medicine and Engineering; Ministry of Education; School of Public Health; Southeast University; Nanjing 210009; P.R. China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials & College of Materials Science and Engineering, Donghua University, Shanghai 201620, China Department of Orthopedics, Nanhai Hospital of Southern Medical University and Foshan Nanhai District People’s Hospital, Guangdong 528200, China State Key Laboratory for Conservation and Utilization of Subtropical Agro‐bioresources Guangxi Research Center for Microbial and Enzyme Engineering Technology College of Life Science and Technology Guangxi University Nanning People's Republic of China Provincial Measles/Rubella Laboratory, Hubei Provincial Center for Disease Control and Prevention, Wuhan,China Key Laboratory of Urban Agriculture, College of Bioscience and Resources Environment, Beijing University of Agriculture, Beijing 102206, China Department of Anatomy and K. K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, China Capital Institute of Paediatrics, Beijing 100020, China Key Laboratory of Endemic and Ethnic Diseases of The Ministry of Education, Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai, China 4Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania. Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health, & Collaborative Innovation Center of Suzhou Nano Science and Technology Southeast University Nanjing China; Jiangsu Key Laboratory for Biomaterials and Devices Southeast University Nanjing China College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China. Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials Science Zhejiang Normal University Jinhua Zhejiang 321004 China Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, Beijing, P.R. China. State Key Laboratory of Crop Stress Biology for Arid Areas, Center of Bioinformatics, College of Life Sciences, Northwest A&F University, Shaanxi, Yangling, China Department of Microbiology and Infectious Disease Center School of Basic Medical Sciences Peking University Health Science Center Beijing China College of Materials Science and Opto-Electronic Technology University of Chinese Academy of Sciences Beijing 101408 P. R. China; Department of Chemistry and Biochemistry University of Oregon Eugene Oregon 97403 USA The Affiliated Lihuili Hospital, Ningbo University, Ningbo, China *Biomedical Engineering, University of Houston, Houston, TX 77204; Wuxi Maternity and Child Health Hospital; Wuxi city; China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua321004, China Thoracic Disease Research Unit, Division of Pulmonary and Critical Care Medicine, Department of Biochemistry and Molecular Biology Cancer Center and College of Medicine, Mayo Clinic Rochester MN USA Department of Pharmacy, Shaanxi Provincial Hospital of Tuberculosis Prevention and Treatment, Xi’an 710100, P. R. China Laboratory of Biomimetic Nanomaterials Department of Orthodontics Peking University School and Hospital of Stomatology National Engineering Laboratory for Digital and Material Technology of Stomatology Beijing Key Laboratory of Digital Stomatology Beijing China Department of Orthopedics and Rehabilitation Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China; Division of Advanced Nanomaterials, Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences (CAS), Suzhou 215123, China School of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China 1Key Laboratory of Environmental Medicine and Engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing, P.R. China. College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China; Municipal Hospital of Qingdao City, Qingdao, China Division of Allergy and Immunology, Joseph Stokes Jr. Research Institute at The Children's Hospital of Philadelphia, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. i‐Lab Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences 398 Ruoshui Road Suzhou 215123 P. R. China College of Biotechnology and Bioengineering, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310014, Zhejiang Province, China Central Laboratory, The Affiliated Jiangyin Hospital of Nantong University, Wuxi 214400,China The Capital Institute of Pediatrics; Beijing People's Republic of China Department of Anatomy, Histology and Embryology, Preclinical School of Medicine, Air Force Medical University, Xi’an, China State Key Laboratory of Natural and Biomimetic Drugs Department of Microbiology & Infectious Disease Center School of Basic Medical Sciences Peking University Health Science Center Beijing 100191 China College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Chinese Fir Engineering Technology Research Center of the State Forestry and Grassland Administration, Fuzhou 350002, China Division of Immunogenetics (D.H.K., T.Z., S.L., V.C.-N., J.Y., A.P., Y.F., H.H.D.) Department of Pediatrics, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224 Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria/Tianjin Key Laboratory of Remediation & Pollution Control for Urban Ecological Environment, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China. [email protected] Department of Chemistry; Tianjin Key Laboratory of Molecular Optoelectronic Science; School of Science; Tianjin University; Tianjin 300072 Department of Gastroenterology, Digestive Disease Hospital Affiliated Hospital of Zunyi Medical University Zunyi China; The Collaborative InnovAffiliated Hospital of Zunyi Medical Universityation Center of Tissue Damage Repair and Regeneration Medicine of Zunyi Medical University Zunyi China Department of Naval Aeromedicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, People’s Republic of China |
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