abstract |
A PROCEDURE FOR PREPARING COMPOUNDS REPRESENTED BY FORMULA (I) OF ANTIVIRAL ACTIVITY, WHERE AND IS ALKYLENE UNSATURATED OR NOT; Z IS N O R5C, WHERE R5 IS H OIL. WHEN Z IS N, R IS DIFFERENT FROM H, M IS 0 O 1; R IS H O ALKYL OPTIONALLY REPLACED BY HYDROXY OR METOXY; R1 AND R2 ARE HALOGEN, METHYL, NITRO OR TRIFLLUORMETHYL; AND R3 AND R4 ARE HO ALKYL PREPARED TO REACT BY A COMPOUND OF FORMULA II, WHERE HAL IS CHLORINE, BROMINE OR IODINE, WITH A SALT OF ALKALINE METAL OF A COMPOUND OF FORMULA III AND, IF DESIRED, ETERIFY A COMPOUND OF FORMULA I DONDER IS HYDROXYALKYL WITH A METHYL HALIDE IN THE PRESENCE OF A STRONG BASE AND, IF DESIRED, CONVERT A BASIC COMPOUND OBTAINED TO A SALT OF ACID ADDITION THEREOF. |