| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41a639aa11b9b2f8063a3e6b8b22b557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_700ff9a01db2075489cb7ed87392dc28 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1688
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate |
2005-05-12^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2011-09-01^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99259b2aeef34ce38fca8847b393797e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7514522547fb80a4644195d209f7994
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67fa30d4847a707e4e5e7cfcb19aacd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8c20223878f4a0fe8e30d3925aaea9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32f24338bca1dc2d209523aa77cc912a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e68dfaefc7bafdb36cc7c0d11f18a2a |
| publicationDate |
2011-09-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AU-2005244840-B2 |
| titleOfInvention |
Microspheres comprising protein and showing injectability at high concentrations of said agent |
| abstract |
The present invention relates to composition of microparticles comprising a suspension of substantially amorphous protein microparticles, the composition providing a concentration of at least about 50 mg of said protein per ml of said composition, and the protein has a molecular weight of at least about 25,000 Daltons. In accordance with the method of production, the active agent is dissolved in an aqueous or aqueous-miscible solvent containing a dissolved phase-separation enhancing agent (PSEA) to form a solution in a single liquid phase. The solution is subjected to a liquid-solid phase separation to cause the active agent to form small spherical that are substantially amorphous or non-crystalline and are injectable through fine gauge needles at high concentrations. The invention has special application for higher molecular weight proteins. |
| priorityDate |
2004-05-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |