abstract |
-C,D 2-methylene-19-norvitamin D analogs are provided including compounds of formula 1, in which R is a straight or branched chain alkyl or alkylene group having from 8 to 27 carbons and bearing an OY group; and Y, Y and Y are independently selected from H or hydroxy-protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions. Formula(I) |