http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014248936-B2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e1fa4afc2138cbf8122e25f5082c8c1
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
filingDate 2014-03-11^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-07-09^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1c467636e6abc50b9c85a52cc64beb2
publicationDate 2020-07-09^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2014248936-B2
titleOfInvention Improved recombinant protein expression using a hybrid CHEF1 promoter
abstract The invention provides expression vectors and host cells for high-level expression of recombinant proteins. The expression vectors comprise Chinese hamster ovary elongation factor 1-α (CHEF1) transcriptional regulatory DNA elements and a cytomegalovirus (CMV) promoter and/or a human adenovirus tripartite leader (AdTPL) sequence. The invention achieves increased protein expression and better productivity of host cells compared to previously described expression systems.
priorityDate 2013-03-12^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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