http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2018360752-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b698c934c4b923aa5bc9e441eb68d5d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 |
| filingDate | 2018-11-05^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92d68bb37673ca51462f47a9ca1e77b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582c753900f92b7b417bd7bb38cc94f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7f5aec16d304aa66d8bedd4206b99e2 |
| publicationDate | 2020-05-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AU-2018360752-A1 |
| titleOfInvention | Imipridones for gliomas |
| abstract | Imipridones selectively modulate Class A G protein-coupled receptors (GPCRs), such as the D2-like subfamily of dopamine receptors, and are useful for treating conditions and disorders in need of such modulation, such as cancers. Specifically, the cancer involves a midline structure of the brain, a cancer having a histone H3 mutation, or both. In addition, methods of identifying whether a subject having these conditions, is likely to be responsive to a treatment regimen, such as imipridone administration, are provided. Furthermore, methods of assessing the effectiveness of a treatment regimen, such as imipridone administration, monitoring, or providing a prognosis for a subject with these condition are also provided. |
| priorityDate | 2017-11-03^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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