http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2019232847-B2

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filingDate 2019-09-18^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-08-27^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c87d86ceb40d5dae4075d3f98c2c89c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5d4588a4dbf866ba1fac540a61a0e95
publicationDate 2020-08-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AU-2019232847-B2
titleOfInvention Bi-terminal pegylated integrin-binding peptides and methods of use thereof
abstract The present invention provides bi-terminal PEGylated peptide conjugates that ntarget an integrin such as avp3 integrin. In particular embodiments, the peptide conjugates of nthe present invention further comprise a biological agent such as an imaging agent or a ntherapeutic agent, e.g., covalently attached to one of the PEG moieties. The peptide conjugates nof the present invention are particularly useful for imaging a tumor, organ, or tissue and for ntreating integrin-mediated diseases and disorders such as cancer, inflammatory diseases, nautoimmune diseases, chronic fibrosis, chronic obstructive pulmonary disease (COPD), lung nemphysema, and chronic wounding skin disease. Compositions and kits containing the peptide nconjugates of the present invention find utility in a wide range of applications including, e.g., nin vivo imaging and immunotherapy.
priorityDate 2014-04-15^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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