abstract |
Provided are a genetically modified immune cell, a preparation method therefor, and an application. The immune cell overexpresses HIL-6 and/or L-GP130. HIL-6 or L-GP130 continuous overexpression/conditionally induced overexpression occurs in the immune cell. In addition to maintaining immune and anti-tumour effects, the present invention reduces the side effects of CAR-T therapy, and has potential value in the treatment of malignant tumours and AIDS. |