| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2015-04-02^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4be91d56f8ccb52c04fdf598ffcb181f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a007793703c281095091e38c91721d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b23f5bf747b3438297943b82f67159a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_134d0302d0b7f4e1efb98f7b5632c393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d653e7246c3789906536ea262d7163b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571d790e60f8c52da323e4d6997ae3f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53449114ce1c3b2c1c0effa63fce8aa0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_820d66bb3f1018831decf34157a9ebae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_440b95a0e6c18e23ac98eade1f275390 |
| publicationDate |
2022-01-11^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112016022700-B1 |
| titleOfInvention |
MACROCYCLIC PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THEM |
| abstract |
MACROCYCLIC PYRIDINE DERIVATIVES. The present invention relates to substituted macrocyclic pyrimidine derivatives of Formula (I) wherein the variables have the meaning defined in the claims. Compounds according to the present invention have EF2K inhibitory activity and optionally also Vps34 inhibitory activity. The invention also relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament. |
| priorityDate |
2014-04-03^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |