abstract |
the present invention relates to compounds of formula (i): (i) and their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use and methods for their preparation. the compounds described herein are useful for inhibiting cytokine maturation of the il-1 family by inhibiting inflammasomes and can be used to treat disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers. |