| abstract |
ANTITUMOR AGENT, METHOD FOR TREATING OR PREVENTING TUMOR, AND USE OF A COMPOUND. An object of the present invention is to provide a medicinal drug greatly improved in antitumor activity and excellent in safety. According to the present invention there is provided a medicinal medicament containing a compound represented by the following general formula (I) or a salt thereof as an active ingredient: [Formula I] wherein X-1 ~ represents a nitrogen atom or a group -CH =, R ^ 1 ^ represents a group -ZR ^ 6 ^, where Z represents a group -CO-, a -CH (OH) - group or the like, R 6 'represents a 5- to 15-membered saturated or unsaturated heterocyclic, monocyclic, dicyclic or tricyclic group having from 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group -O-, a group -CO-, a group -CH (OH) - or a lower alkylene group and A represents wherein R3 ^ represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2 , R ^ 4 ^ represents a |