| abstract |
MONOCLONAL ANTIBODY FOR THE DIAGNOSIS AND TREATMENT OF CARDIOVASCULAR DISEASES, PHARMACEUTICAL COMPOSITION, SET OF REAGENTS USEFUL IN THE DIAGNOSIS OF ATHEROSCLEROTIC INJURIES, AND, USE OF AN ANTIBODY The present invention relates to the field of new technology and use, particularly human. The present invention provides new monoclonal antibodies that specifically and with high affinity recognize sulphatides and sulphated proteoglycans. Anti-sulfatide and anti-sulfate proteoglycan antibodies, described in this descriptive report, are important diagnostic and therapeutic agents to act on pathological processes associated with the appearance of atherosclerotic plaques. Accordingly, the invention provides pharmaceutical compositions comprising the monoclonal antibodies of the invention or fragments derived from these antibodies for therapeutic and diagnostic use in association with cardiovascular diseases. Additionally, the present invention relates to fragments of monoclonal antibodies which recognize sulphatides and sulphated proteoglycans, such that said fragments can be used in the treatment or diagnosis of this pathological condition. |