http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-1059528-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-76 |
| filingDate | 1978-02-06^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1979-07-31^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfe1f89342193fd2f6aeed955d2bc10d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77060370641f4adcaa3f3b7fc682c0fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfd1f8e406873a1031e2c352f29fcf83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db1060564ab9b6eb1c55e51789fd9e4e |
| publicationDate | 1979-07-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-1059528-A |
| titleOfInvention | Process for preparing 5-fluoro-2-methyl-1-indanone |
| abstract | ABSTRACT OF THE DISCLOSURE The invention relates to a novel process for preparing 5-fluoro-2-methyl-1-indanone by reacting under Friedel Crafts conditions fluorobenzene with a novel acid halide of the formula: wherein A is methyl or together with G forms methylidene; B is hydrogen, methyl or halo (Cl. Br. F. I); G is methyl. CH2R or together with A forms methylidene, wherein R is halo. hydroxy or -N-(C1-5 alkyl)2; Z is halo; and (1) when A and G together is methylidene. B is methyl; (2) when A and G are each methyl, B is halo; and (3) when A is methyl and B is hydrogen, G is CH2R. The 5-fluoro-2-methyl-1-indanone obtained is a useful intermediate in the preparation of 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indene-3-acetic acid which is known to possess anti-inflammatory activity. |
| priorityDate | 1973-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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