| abstract |
Abstract of the Disclosure The present invention is concerned with 1,1,1-triaryl-alkylamines. These compounds are pre-pared by reacting the appropriate amides with a suitable hydride reducing agent in an organic solvent to give the compounds of the instant invention. Alter-nately, the compounds of the present invention can also be prepared by reacting the appropriate organometallic compounds with an haloalkylamine. The compounds of the instant invention possess potent anti-diarrheal utility as evidenced by their ability to inhibit gastrointestinal motility. These subject compounds also possess a very low degree of analgesia. |