| abstract |
A Pt(IV) complex of the formula <see Fig.1> wherein A and A' are NH3 or an amino group; R and R1 are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally. |