abstract |
Abstract of the disclosure: Pyrimidine-4,6-dicarboxylic acid diamides, processes for their preparation and the use thereof, and pharmaceuti-cals based on these compounds The invention relates to pyrimidine-4,6-dicarboxylic acid diamides of the formula I (I) in which R1 and R2 have the meanings given. The compounds according to the invention inhibit proline hydroxylase and lysine hydroxylase and can be employed as fibro-suppressants and immunosuppressants. |