| abstract |
The present invention relates to compounds of the general formula I in which R is hydrogen or (C1-C6)-alkyl, R1 is -(CH2)n-NH-X where n is an integer from 1 to 6 and X is, for example, hydrogen or (C1-C6)-alkyl, R2, R3 and R4 are each, for example, hydrogen, r is an integer. from 0 to 3, Y is -(CH2)m-CO- where m is an integer from 1 to 4, Z is oxygen or sulphur and W is, for example, hydroxyl. The compounds of the invention inhibit platelet aggregation, the metastasis of carcinoma cells and osteoclast binding to the bone surfaces. They are therefore useful in therapy and prophylaxis of vascular diseases, cancer and osteoporosis. |