http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2116640-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-828 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 1994-02-28^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0da3fd40ae87b4a926c4400c0c6409f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fe2b4200e03845650df1b734b31d03d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d18c2673daa478e474d1babfa0710ec7 |
publicationDate | 1994-09-26^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2116640-A1 |
titleOfInvention | Carcinoembryonic antigen derivatives |
abstract | Abstract The present invention provides recombinant CEA glycoprotein derivatives and to methods for their production. These recombinant CEA glycoprotein derivatives are characterized in that they are free from cross-reactive CEA-like antigens, antigenically indistingiushable from the soluble form of CEA shed from tumor cells and devoid of ethanolamine. Said derivatives preferably have the amino acid sequence [SEQ ID NO: 1]. The said CEA glycoprotein derivatives may be used as reagents in an immunoassay for the diagnosis of neoplastic diseases. The invention also relates to a DNA encoding a said recombinant CEA glycoprotein derivative such as the DNA having the nucleotide sequence [SEQ ID NO: 2] or a functional equivalent sequence thereof. The present invention also relates to recombinant vectors comprising a said DNA, which recombinant vector is capable of directing the expression of the said DNA in a compatible host cell and to transformed host cells containing such a recombinant vector. The recombinant CEA glycoprotein derivative of the present invention, preferably integrated in a test-kit may be used for determining the presence of tumor cells in a sample of body fluid. |
priorityDate | 1993-03-25^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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