| abstract |
A drug for ameliorating brain diseases which comprises as the active ingredient a compound represented by general formula (1) or a salt thereof wherein R1 represents H, OH, lower alkoxy or lower alkyl; R2 and R3 represent H, optionally substituted lower alkyl, lower alkenyl, optionally substituted phenyl or optionally substituted styryl; and X represents O or N optionally substituted by lower alkyl. Because of inhibiting a decrease in brain neurons and promoting the branching of neurites, this drug is efficacious in the prevention and treatment of dementia, etc. in association with the degeneration and sloughing of brain neurons. |