| abstract |
The subject of the invention is the use of nucleotide sequences coding for antibodies directed against any molecule involved in a phenomenon of transplant rejection (also referred to below as anti-molecule antibodies), for preparation of transgenic cells, or transgenic organs, of mammals non-human, within which said molecules form wholly or in part of the immune complexes with said anti-molecule antibodies, such so that the activity of said molecules in transplant rejection phenomena either totally or partially inhibited, said cells or organs transgenics of non-human mammals intended to be transplanted into a patient. |