http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2432976-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2001-12-21^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c7e02d71d59533abb822a11557be191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0a141fed59a7f5602d571ceb5ec85d |
| publicationDate | 2002-08-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2432976-A1 |
| titleOfInvention | Reagents and methods for identifying and modulating expression of tumor senescence genes |
| abstract | This invention identifies tumor senescence genes induced by treatment with cytotoxic agents. The invention provides reagents and methods for identifyin g compounds that induce expression of these cellular genes and produce cellula r senescence, particularly senescence in tumor cells. The invention also provides reagents that are recombinant mammalian cells containing recombinan t expression constructs that express a reporter gene under the transcriptional control of a promoter for a gene the expression of which is modulated in senescent cells, and methods for using such cells to identify compounds that modulate expression of these cellular genes. |
| priorityDate | 2000-12-21^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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