http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2466129-A1

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filingDate 2002-11-01^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22fb84ee43777285312171b2e6f244e1
publicationDate 2003-05-08^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2466129-A1
titleOfInvention Methods for genetically modifying a target population of an organism
abstract A method for genetically modifying a target population of an organism, comprising the steps of 1. providing a modified organism, wherein the modified organism is capable of sexually reproducing with an organism of the target population, and wherein a selected gene in the germline of the modified organism is disrupted by having inserted into it a sequence-specific nonMendelian selfish gene; 2. introducing the modified organism into the target population. A method for genetically modifying a target population of an organism, comprising the steps of 1. Introducing a homing endonuclease gene (HEG) into the germline of an organism which is capable of sexually reproducing with organisms of the target population; 2. introducing the modified organism into the target population. The HEG may encode a recombinant endonuclease, for example an endonuclease with a zinc-finger DNA binding domain and a sequence non-specific nuclease domain.
priorityDate 2001-11-01^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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