| abstract |
Compound of formula (I): in which: R1 represents an aryl group, heteroaryl, optionally substituted alkyl, or a group of formula -(CO) -CR6R7NR8R9 in which R6, R7, R8 and R9 are as defined in description, R2 represents a hydrogen atom or an alkyl group, R3 represents a hydrogen atom or an alkyl group optionally substituted, R4 represents a hydrogen atom or an alkyl group optionally substituted, or else R3 and R4 form together, with the atom of carbon carrying them, a mono-, bi- or tricyclic, saturated or unsaturated, from 3 to 18 links, possibly including one or more heteroatoms chosen from O, S and N, and optionally substituted, n represents zero, 1 or 2, Ar represents an aryl or heteroaryl group, R5 represents an amino, guanidino, cyano or amidino group optionally substituted, its optical isomers as well as its addition salts with an acid pharmaceutically acceptable. |