abstract |
A phosphodiesterase 10A inhibitor which contains as an active ingredient a quinoline derivative represented by the following formula (I) or a pharmacologically acceptable salt of the derivative. (I) [In the formula, n is an integer of 1 to 4; R1 represents (un)substituted lower alkyl, -C(=Y)R9, etc.; R2 represents hydrogen, (un)substituted lower alkyl, etc.; R3 represen ts (un)substituted lower alkyl, (un)substituted aryl, (un)substituted heterocyclic group, etc.; and R4 represents halogeno, etc.] |