http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2507811-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3561edb5c93a789a3a54fb949beab38
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6421
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64
filingDate 2003-12-08^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc69a2a489057f5a2674b614d6accc15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_877fb28724d6449fe9edf763513fd5dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d7ec0f6ac1323a73650debe12ee1125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_221c7f93a3acef376dd82d0bf4411f63
publicationDate 2004-06-24^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2507811-A1
titleOfInvention Process for the determination of the primary structure of the messenger rna coding for the human recombinant endooligopeptidase a (heopa) [af217798]
abstract This invention refers to the recombinant human endooligopeptidase (hEOPA), polynucleotide which codes for the hEOPA, polynucleotide which allow the expression of the EOPA in prokaryotes and eukaryotes, including the human beings; use of the synthetic substrates for the determination of the proteolytic activity of the hEOPA, or of its chaperon activity or its activi ty as soluble peptide receptor; obtaining and using of the specific antibodies and inhibitors of its oligopeptide binding activity, as agonists, competitor s and antagonists, which are able to disturb its interaction and the complex formation with other proteins. The invention also refers to the application of the natural and recombinant protein, chemically or genetically modified whic h aim is the diagnosis and/or the application in congenital, infectious and degenerative pathologic conditions of the central nervous system, and for psychiatric and behavioral dysfunctions. It is also proposed the application of the inhibitors and competitors for the interaction of EOPA with ligands, including antibodies or their derivatives, for the treatment of tissular and neurodegenerative pathologies.
priorityDate 2002-12-09^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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