http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2512310-C

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filingDate 2003-12-24^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-09-25^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5eae712a26ede5da67cae0e5eb2b3df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67eb2c8460f325a56fb8b0fcc1412589
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c11a20cdb30ad4e1f004a4d4013c3037
publicationDate 2012-09-25^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2512310-C
titleOfInvention Improved linkers for radiopharmaceutical compounds
abstract A new and improved method for extending the half life of pharmaceutical compounds for use in diagnostic imaging or therapy uses a novel linker to attach a diagnostic or therapeutic moiety to a targeting peptide or another diagnostic or therapeutic moiety. The resulting compound may have the general formula M-N-O-P-Q, wherein M is the diagnostic or therapeutic moiety, N-O-P is the linker of the present invention, and Q is the targeting peptide. In another embodiment the compounds may have the formula M-N-O-P-M, wherein M is independently a diagnostic or therapeutic moiety and N-O-P is the linker of the invention. Methods for imaging or treating a patient using the compounds of the invention are also provided. Methods and kits for preparing a diagnostic imaging agent from the compound are further provided. Methods for radiotherapy of a patient using the compounds are further provided, as are methods for preparing a radiotherapeutic agent from the compounds.
priorityDate 2003-01-13^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6P4N0
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426259643
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID154113627
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6750
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419503663
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415967719
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419534614
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO73909
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419507775
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419507729
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45845
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419493326
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100009181
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID44965
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCE3YBA4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ3T478
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4025
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ864S7
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID236702
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP79885
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396279
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID11846228
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP01308
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21704
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04667
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID8369
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ64191

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