abstract |
The present invention provides a carbamoyl-type benzofuran derivative of the formula [1]: See formula I wherein Ring Z is a group of the formula: See formula II etc. ; A is a single bond, and the like; Y is a cycloalkanediyl group, etc.; R4 and R5 are the same or different and each is an optionally substituted lower alkyl group, etc.; R1 is a halogen atom, etc.; Ring B of the formula: See formula III is an optionally substituted benzene ring; and R3 is a hydrogen atom. etc., or a pharmaceutically acceptable salt thereof, which is useful as an FXa inhibitor. |