http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2545119-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47f079fed01315e7f0429c70e359a9b7
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-20
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-20
filingDate 2003-11-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fd39cb4669fd6b16eb8b50a0660526a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e108ab81fd4e40dd993f9956d4fe9ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6283bebaf09a6c4cb0aa7eafae71943c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8e574171dc2210ce0e5728d5c39092e
publicationDate 2005-05-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2545119-A1
titleOfInvention A process for the manufacture of zonisamide
abstract The present invention describes an improved process for the preparation of 1,2Benzisoxazole-3-methanesulphonamide (Zonisamide), a well known anti-epileptic agent which possesses anti-convulsant and anti-neurotoxic effects. Other aspect of this invention are isolation of a key intermediate, viz., crystalline sodium chloride associated 1,2Benzisoxazole-3-methane sodium sulfonate (BOS-Na:NaCl). The isolated crude BOSNa:NaCl is directly converted to Zonisamide using controlled molar ratio of chlorosulfonic acid to avoid the disulfonated side products. The analytical characteristics like IR and XRD data of the BOS-Na:NaCl are also reported to confirm its nature.
priorityDate 2003-11-11^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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