| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 |
| filingDate |
2006-09-22^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60048b77a5657a17bf17ee38bb50d29b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11c45c7922c99062e2e34c17b2c55803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c170c16e700cc5b37659fe44122d2d80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1318682d0fdec0badd63dfe0d49aa96d |
| publicationDate |
2007-09-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2643078-A1 |
| titleOfInvention |
Method and apparatus for avalanche-mediated transfer of agents into cells |
| abstract |
The present invention provides a method and apparatus for transferring an agent into a cell. The method includes the steps of providing an agent outside of a cell and generating a vapor bubble and a plasma discharge between an avalanche electrode and a conductive fluid surrounding the cell. The vapor bubble and plasma discharge generate a mechanical stress wave and an electric field, respectively. The combination of this mechanical stress wave and electric field results in permeabilization of the cell, which in turn results in transfer of the agent into the cell. |
| priorityDate |
2006-02-22^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |