http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2673791-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acb995eb22f9306adb4ab9027d8fda8f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1024 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 2007-12-27^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eb313e986c1405913c3d43d41020a8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c653be6480a50385a4a56e75848c751 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf513faea44988335f5abf0554b44593 |
| publicationDate | 2008-07-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2673791-A1 |
| titleOfInvention | Cecropin b and hb-107 derived short bio-active peptides for cellular immune modulation |
| abstract | Peptides having four to fourteen residues are disclosed that possess biological activity. These peptides constitute short fragments of the peptide HB-107 (SEQ ID NO:1), which itself is a fragment of the antimicrobial protein cecropin B, and exhibit cell stimulatory, migratory and anti-inflammatory properties. As keratinocytes are especially sensitive to these effects, the disclosed peptides comprise a useful agent for the medical treatment of injury to the skin, such as from diabetic ulcers. The peptides also are effective in preventing and reversing skin surface damage resulting from various environmental insults. Importantly, the therapeutic effects of the peptides manifest at concentrations equal to or greater than those of peptide HB-107, and thus represent a less expensive, more versatile means for developing effective therapies. Methods for the production and use of these peptides are also disclosed. |
| priorityDate | 2007-01-05^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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