Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a366865e43e09246f6aed992535dfd28 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y111-01007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01011 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-54 |
filingDate |
2008-01-23^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc9908c04e9b4ac9019c0b287947bec5 |
publicationDate |
2009-01-15^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2692791-A1 |
titleOfInvention |
Use of hydrolytic and oxidative enzymes to dissolve biofilm in airway passages |
abstract |
A composition for removal of biofilm in the airway passage is useful for the treatment of infections such as pneumonia caused by Mycoplasma pneumoniae. In general, the composition comprises: (1 ) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the airway; and (2) a pharmaceutically acceptable carrier suitable for administration into the airway The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an infection based on the ability of the composition to dissolve biofilm in the airway. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019142864-A1 |
priorityDate |
2007-07-06^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |