http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2692791-A1

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publicationDate 2009-01-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2692791-A1
titleOfInvention Use of hydrolytic and oxidative enzymes to dissolve biofilm in airway passages
abstract A composition for removal of biofilm in the airway passage is useful for the treatment of infections such as pneumonia caused by Mycoplasma pneumoniae. In general, the composition comprises: (1 ) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the airway; and (2) a pharmaceutically acceptable carrier suitable for administration into the airway The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an infection based on the ability of the composition to dissolve biofilm in the airway.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019142864-A1
priorityDate 2007-07-06^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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