http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2836827-C

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4bb2b15ee842821e2028150cbf93813
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-02
filingDate 2006-05-04^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-05-03^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_950d9736d1561b2affd35df43776ebf3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33c263ab707fb43b2819527c7f2bad1c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ad50252143fab64a8b647789717c4ea
publicationDate 2016-05-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2836827-C
titleOfInvention Alpha amino acid ester-drug conjugates hydrolysable by carboxylesterases
abstract Covalent conjugation of an alpha amino acid ester to a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid, leads to accumulation of the carboxylic acid hydrolysis product in the cell and enables improved or more prolonged enzyme or receptor modulation relative to the unconjugated modulator.
priorityDate 2005-05-05^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID22646562
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP12705
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO88444
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4GCL1
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57820957
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP17402
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414558479
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ289M4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP12704
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID282457
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID421210319
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414633492
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC1D0Z6
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11677
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414633486
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4GBY0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP86325
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57820516
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57642699
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25589
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7000049
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID75555
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP25274
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6714
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68243
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID382053
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9IGQ6
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID886358
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5770
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1487307
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID56965201

Showing number of triples: 1 to 1000 of 1270.

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