Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78941ed5a01bfbcd48376e1fdb485b19 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
filingDate |
2015-01-02^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-06-21^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74aa7f7a53501ebde667599387eb6630 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_740f8c7b90490f8dabf6a4a110c80f83 |
publicationDate |
2022-06-21^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2935717-C |
titleOfInvention |
Uracil isostere and pharmaceutical compositions thereof useful as deoxyuridine triphosphatase inhibitors |
abstract |
Provided herein are dUTPase inhibitors of formula: and compositions comprising such compounds. The use of such compounds and compositions for inhibiting dUTPase, enhancing the efficacy of a dUTPase directed therapy, and reversing resistance to a dUTPase directed therapy, in the treatment of a disease such as cancer, are provided. |
priorityDate |
2014-01-03^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |