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filingDate 2015-01-02^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-21^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74aa7f7a53501ebde667599387eb6630
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_740f8c7b90490f8dabf6a4a110c80f83
publicationDate 2022-06-21^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2935717-C
titleOfInvention Uracil isostere and pharmaceutical compositions thereof useful as deoxyuridine triphosphatase inhibitors
abstract Provided herein are dUTPase inhibitors of formula: and compositions comprising such compounds. The use of such compounds and compositions for inhibiting dUTPase, enhancing the efficacy of a dUTPase directed therapy, and reversing resistance to a dUTPase directed therapy, in the treatment of a disease such as cancer, are provided.
priorityDate 2014-01-03^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB5EI65
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ0HSH8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ4UR35
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID67519
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8Y0U6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07606
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA9M7H5
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7298
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA6UB24
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ1LK81
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID126941
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0TYI1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6A761
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4TCR4
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419596966
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID425115491
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1181692
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8DUI4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ3YY33
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID22171
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID58308596
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB7KQG2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID172149
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0U1I2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA1WZE9
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419552265
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB0U0Z5
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414858317
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB3H338
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45539123
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135398635
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID169371
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID454051202
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB8E4J3
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1854
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA9M657
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414008313
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9221
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9548687
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1186967
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4YJH3
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419552392
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57203323
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16790
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8K9C3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ603S2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC1CJD5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA3CMU9
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID56906756
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID13712
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC3K3Q8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC4L1C9
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID2048
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7108
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA9MKN5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ07PP0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA5FZ98
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1682482
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID58026964

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